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$382+ Cheap flights from South America to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
BOG — TYS
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from South America to Knoxville

Keep the following information in mind while searching for South America to Knoxville flight deals. Data was last updated March 31, 2025.

Round-trip from

$717
(American Airlines)

One-way from

$382
(Kiwi.com)
From South America to Knoxville McGhee Tyson
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One-way flight from South America to Knoxville McGhee Tyson
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Find flight deals from South America to Knoxville

Cheapest flights from South America to Knoxville
Explore the most affordable flight options available from South America to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/39:00 pmSCL - TYS
1 stop25h 20mAmerican Airlines
Fri 6/276:04 amTYS - SCL
1 stop24h 56mAmerican Airlines
Deal found 3/30$717
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:35 amGYE - TYS
1 stop15h 46mAmerican Airlines
Thu 12/47:01 amTYS - GYE
1 stop15h 04mAmerican Airlines
Deal found 3/30$746
This eDestinos deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/411:05 pmSCL - TYS
2 stops19h 55mLATAM Airlines
Tue 12/232:32 pmTYS - SCL
2 stops13h 28mLATAM Airlines
Deal found 3/30$879
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2012:17 pmGYE - TYS
2 stops30h 49mUnited Airlines
Sun 4/277:00 amTYS - GYE
2 stops31h 46mUnited Airlines
Deal found 3/30$962
This Ovago deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/233:30 amGYE - TYS
2 stops18h 53mAvianca
Thu 12/45:50 amTYS - GYE
2 stops20h 55mAvianca
Deal found 3/30$1,230
This Ovago deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/193:35 amGYE - TYS
2 stops19h 18mMultiple Airlines
Mon 11/107:10 pmTYS - GYE
2 stops22h 26mMultiple Airlines
Deal found 3/30$1,550

Cheapflights Fare Finder

Customize your flight search to find flights from South America to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from South America to Knoxville that are best for you.

Fly from

South America

Fly to

Knoxville

Route

Depart

Return

Price

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Tue 6/3

9:00 pm-10:20 pm

1 stop25h 20m

Knoxville McGhee Tyson

Fri 6/27

6:04 am-7:00 am

1 stop24h 56m

$717

SantiagoKnoxville

SCL - TYS

SCLTYS

Santiago Arturo Merino Benitez

Mon 8/4

11:05 pm-7:00 pm

2 stops19h 55m

Knoxville McGhee Tyson

Tue 12/23

2:32 pm-6:00 am

2 stops13h 28m

$879

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Sun 4/20

12:17 pm-8:06 pm

2 stops30h 49m

Knoxville McGhee Tyson

Sun 4/27

7:00 am-1:46 pm

2 stops31h 46m

$962

GuayaquilKnoxville

GYE - TYS

GYETYS

Guayaquil Jose Joaquin de Olmedo

Sun 4/20

6:00 am-11:29 pm

1 stop16h 29m

Knoxville McGhee Tyson

Sun 4/27

6:55 am-8:53 pm

1 stop14h 58m

$1,695

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Mon 4/7

11:30 am-6:32 pm

2 stops30h 02m

$382

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sun 4/6

3:15 am-10:05 am

2 stops29h 50m

$562

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Sun 4/6

12:35 am-11:15 pm

1 stop21h 40m

$641

QuitoKnoxville

UIO - TYS

UIOTYS

Quito Mariscal Sucr

Mon 4/7

6:00 am-11:29 pm

1 stop16h 29m

$645

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Best time to book a flight from South America to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from South America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South America to Knoxville

What is the cheapest month to book a flight from South America to Knoxville?

Currently, January is the cheapest month in which you can book a flight from South America to Knoxville (average of $296). Flying from South America to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SA to TYS?

Find hourly flight availability from South America to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

When flying from South America to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 31, 2025.
LATAM Airlines
7.5
Good
1,754 reviews

Crew

8.1

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
LATAM Airlines
7.5
Good
1,754 reviews
LATAM Airlines
7.5
Good
1,754 reviews

Crew

8.1

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
United Airlines
7.4
Good
8,614 reviews
LATAM Airlines
7.5
Good
1,754 reviews

Crew

8.1

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
American Airlines
7.2
Good
10,000 reviews
LATAM Airlines
7.5
Good
1,754 reviews

Crew

8.1

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.
Avianca
6.7
Okay
2,301 reviews
LATAM Airlines
7.5
Good
1,754 reviews

Crew

8.1

Boarding

7.6

Entertainment

7.0

Comfort

7.4

Food

6.7

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

Find useful and relevant information for your journey from South America to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from South America?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from South America to Knoxville.

  • What are the cheapest airlines to fly from South America to Knoxville one-way?

    $562 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $641 and $645, respectively.

  • What are the most popular routes from South America to Knoxville?

    When deciding which route to take from South America to Knoxville consider Quito Mariscal Sucr - Knoxville McGhee Tyson, Santiago Arturo Merino Benitez - Knoxville McGhee Tyson or Guayaquil Jose Joaquin de Olmedo - Knoxville McGhee Tyson as they are the most popular.

  • Can I find deals for flights from South America to Knoxville that include hotel bookings?

    Yes. In addition to deals on South America to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South America to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South America to Knoxville.

  • Can I find deals for business class flights from South America to Knoxville?

    Yes. Cheapflights offers flight deals from South America to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South America to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from South America to Knoxville (average of $296). Flying from South America to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South America?

Book flights to South America if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for South America to Knoxville

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Top airline flying from South America to Knoxville

Discover the top airline that operate flights from South America to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$447Average$834FlexibilityNo cancel feeOn-timeN/A
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