HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$259+ Cheap flights from Sioux Falls to Knoxville (FSD - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — TYS
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Sioux Falls to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Sioux Falls to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$259
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$343
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Knoxville McGhee Tyson flights.
Search Deals
From Sioux Falls Joe Foss Field to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($119 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Sioux Falls to Knoxville

Cheapest flights from Sioux Falls to Knoxville
Explore the most affordable flight options available from Sioux Falls to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/25:30 pmFSD - TYS
1 stop5h 25mAmerican Airlines
Tue 5/612:34 pmTYS - FSD
1 stop5h 31mAmerican Airlines
Deal found 4/16$259
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/24:20 pmFSD - TYS
1 stop5h 39mDelta
Tue 5/65:30 amTYS - FSD
2 stops7h 14mDelta
Deal found 4/16$264
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2411:45 amFSD - TYS
2 stops10h 20mUnited Airlines
Fri 5/305:38 pmTYS - FSD
1 stop5h 14mUnited Airlines
Deal found 4/17$483
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/217:17 pmFSD - TYS
1 stop19h 05mMultiple Airlines
Thu 4/247:15 amTYS - FSD
2 stops26h 55mMultiple Airlines
Deal found 4/17$505
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/217:17 pmFSD - TYS
1 stop19h 05mAllegiant Air
Thu 4/241:55 pmTYS - FSD
1 stop30h 42mAllegiant Air
Deal found 4/17$715

Cheapflights Fare Finder

Customize your flight search to find flights from Sioux Falls to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Sioux Falls to Knoxville that are best for you.

Fly from

Sioux Falls

Fly to

Knoxville

Route

Depart

Return

Price

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Fri 5/2

5:30 pm-11:55 pm

1 stop5h 25m

Knoxville McGhee Tyson

Tue 5/6

12:34 pm-5:05 pm

1 stop5h 31m

$259

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Fri 5/2

4:20 pm-10:59 pm

1 stop5h 39m

Knoxville McGhee Tyson

Tue 5/6

5:30 am-11:44 am

2 stops7h 14m

$264

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Sat 5/24

11:45 am-11:05 pm

2 stops10h 20m

Knoxville McGhee Tyson

Fri 5/30

5:38 pm-9:52 pm

1 stop5h 14m

$483

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Mon 4/21

7:17 pm-3:22 pm

1 stop19h 05m

Knoxville McGhee Tyson

Thu 4/24

7:15 am-9:10 am

2 stops26h 55m

$505

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Mon 4/21

7:17 pm-3:22 pm

1 stop19h 05m

Knoxville McGhee Tyson

Thu 4/24

1:55 pm-7:37 pm

1 stop30h 42m

$715

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Compare providers for flights from Sioux Falls to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Sioux Falls-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Sioux Falls-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Knoxville

What is the cheapest month to book a flight from Sioux Falls to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Sioux Falls to Knoxville (average of $296). Flying from Sioux Falls to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FSD to TYS?

Find hourly flight availability from Sioux Falls to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

It’s optimal to fly from Sioux Falls to Knoxville at noon. By choosing this option you can save up to 39% on the cost of your flight, compared to a flight in the morning.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 17, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from Sioux Falls to Knoxville. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Sioux Falls to Knoxville round-trip?

    Cheapflights users have booked flights from Sioux Falls to Knoxville round-trip from $259. Other airlines that can offer you cheap pricing are Delta, from $264, and United Airlines, from $483. American Airlines is priced at 38% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Sioux Falls to Knoxville that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Knoxville.

  • Can I find deals for business class flights from Sioux Falls to Knoxville?

    Yes. Cheapflights offers flight deals from Sioux Falls to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Sioux Falls to Knoxville (average of $296). Flying from Sioux Falls to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Sioux Falls to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Sioux Falls to Nashville flights
Rapid City to Nashville flights
Rapid City to Knoxville flights
Sioux Falls to Memphis flights
Aberdeen to Nashville flights
Rapid City to Chattanooga flights

Top 3 airlines flying from Sioux Falls to Knoxville

Discover the top 3 airlines that operate flights from Sioux Falls to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$221Average$343FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$393FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$520FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.