HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$85+ Cheap flights from San Francisco to Knoxville (SFO - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — TYS
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Francisco to Knoxville with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

The best prices from San Francisco to Knoxville McGhee Tyson are usually found in August or February, booked 57 days in advance, depart on a Tuesday or Wednesday and return on a Tuesday

Cheap flight deals from San Francisco to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated febrero 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$170
(Frontier)

One-way from

$85
(Frontier)

Popular in

December

Cheapest in

August

Average price

$438
Provider with most accurate pricing for San Francisco-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Knoxville McGhee Tyson flights.
Search Deals
From San Francisco to Knoxville McGhee Tyson
Search Deals
One-way flight from San Francisco to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($36 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals

Find flight deals from San Francisco to Knoxville

Cheapest flights from San Francisco to Knoxville
Explore the most affordable flight options available from San Francisco to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/276:00 amSFO - TYS
1 stop6h 23mFrontier
jue. 4/104:31 pmTYS - SFO
1 stop11h 13mFrontier
Deal found 2/20$170
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/262:19 pmSFO - TYS
1 stop6h 23mDelta
mar. 4/86:45 amTYS - SFO
1 stop9h 30mDelta
Deal found 2/20$309
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/1112:21 amSFO - TYS
1 stop7h 17mAmerican Airlines
sáb. 4/196:21 pmTYS - SFO
1 stop7h 15mAmerican Airlines
Deal found 2/19$339
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/1712:08 amSFO - TYS
1 stop7h 07mUnited Airlines
mié. 4/2310:40 amTYS - SFO
1 stop9h 32mUnited Airlines
Deal found 2/19$382
This Orbitz deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/258:25 amSFO - TYS
1 stop10h 32mMultiple Airlines
jue. 3/274:23 pmTYS - SFO
1 stop11h 20mMultiple Airlines
Deal found 2/18$391
This Alaska Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/48:20 amSFO - TYS
1 stop7h 52mAlaska Airlines
vie. 3/76:50 pmTYS - SFO
1 stop30h 20mAlaska Airlines
Deal found 2/19$569

Find flights from San Francisco to Knoxville within your budget

Customize your flight search to find flights from San Francisco to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

San Francisco

Fly to

Knoxville

Route

Depart

Return

Price

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

jue. 3/27

6:00 am-3:23 pm

1 stop6h 23m

Knoxville McGhee Tyson

jue. 4/10

4:31 pm-12:44 am

1 stop11h 13m

$170

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

mié. 3/26

2:19 pm-11:42 pm

1 stop6h 23m

Knoxville McGhee Tyson

mié. 4/9

12:55 pm-6:53 pm

1 stop8h 58m

$309

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

vie. 4/11

12:21 am-10:38 am

1 stop7h 17m

Knoxville McGhee Tyson

sáb. 4/19

6:21 pm-10:36 pm

1 stop7h 15m

$339

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

jue. 4/17

12:08 am-10:15 am

1 stop7h 07m

Knoxville McGhee Tyson

mié. 4/23

10:40 am-5:12 pm

1 stop9h 32m

$382

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

mar. 3/25

8:25 am-9:57 pm

1 stop10h 32m

Knoxville McGhee Tyson

jue. 3/27

4:23 pm-12:43 am

1 stop11h 20m

$391

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

mar. 3/4

8:20 am-7:12 pm

1 stop7h 52m

Knoxville McGhee Tyson

vie. 3/7

6:50 pm-10:10 pm

1 stop30h 20m

$569

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

jue. 3/27

6:00 am-3:23 pm

1 stop6h 23m

$85

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

lun. 4/14

11:59 pm-2:38 pm

1 stop11h 39m

$198

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

lun. 4/14

11:05 pm-3:51 pm

2 stops13h 46m

$234

San FranciscoKnoxville

SFO - TYS

SFOTYS

San Francisco

mié. 4/2

8:25 am-9:57 pm

1 stop10h 32m

$284

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 11 results
1
2

Compare providers for flights from San Francisco to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Knoxville in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from San Francisco to Knoxville

Get recent, data-driven insights about flights from San Francisco to Knoxville including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from San Francisco to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Knoxville. Price data was last updated on February 14, 2025.

Booking 57 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Francisco to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Francisco to Knoxville?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Knoxville (average of $296). Flying from San Francisco to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to TYS?

Find hourly flight availability from San Francisco to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

It’s optimal to fly from San Francisco to Knoxville in the afternoon. By choosing this option you can save up to 12% on the cost of your flight, compared to a flight at noon.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated febrero 20, 2025.
Read through reviews of airlines operating flights from San Francisco to Knoxville, such as Alaska Airlines, Delta and United Airlines. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,697 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Alaska Airlines
8.0
Very good
9,697 reviews
Alaska Airlines
8.0
Very good
9,697 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Delta
8.0
Very good
8,219 reviews
Alaska Airlines
8.0
Very good
9,697 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

United Airlines
7.4
Good
8,765 reviews
Alaska Airlines
8.0
Very good
9,697 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,697 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Frontier
6.0
Okay
3,355 reviews
Alaska Airlines
8.0
Very good
9,697 reviews

Comfort

7.9

Entertainment

7.1

Food

7.1

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from San Francisco to Knoxville round-trip?

    Flying on Frontier is currently your cheapest option to Knoxville, with prices starting at $170. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $309 and $339, respectively. Users have found that Frontier is 65% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from San Francisco to Knoxville one-way?

    One-way options have recently been found by users for as low as $85 on Frontier. Other airlines that offer cheap prices include American Airlines from $198 and United Airlines from $234 one-way.

  • Where are the most common layover locations when flying from San Francisco to Knoxville?

    San Francisco to Knoxville flights have a layover in Dallas most often.

  • What are some popular things to do or see while on a layover in Dallas?

    Most Dallas visitors opt to spend their time experiencing American Airlines Center, Dos Equis Pavilion, and Majestic Theatre. Those on a layover in Dallas interested in visiting American Airlines Center, Dos Equis Pavilion, or Majestic Theatre can do so by traveling 15.0 mi, 18.3 mi, and 16.1 mi, respectively from Dallas/Fort Worth. Those looking to explore during their layover in Dallas can rent a car from Dallas/Fort Worth for about $50 per day.

  • Where are the least popular layover locations for San Francisco to Knoxville flights?

    Flights departing from San Francisco and landing in Knoxville layover in Charlotte least frequently.

  • Can I find deals for flights from San Francisco to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Francisco to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Knoxville.

  • Can I find deals for business class flights from San Francisco to Knoxville?

    Yes. Cheapflights offers flight deals from San Francisco to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from San Francisco to Knoxville (average of $296). Flying from San Francisco to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Nashville flights
San Francisco to Nashville flights
Ontario to Nashville flights
Burbank to Nashville flights
Santa Ana to Nashville flights
Sacramento to Nashville flights
San Diego to Nashville flights
San Jose to Nashville flights
Las Vegas to Nashville flights
Oakland to Nashville flights
Los Angeles to Memphis flights
Long Beach to Nashville flights
San Francisco to Memphis flights
Fresno to Nashville flights
Palm Springs to Nashville flights
Ontario to Memphis flights
Ontario to Knoxville flights
Los Angeles to Knoxville flights
Monterey to Nashville flights
Sacramento to Knoxville flights
San Diego to Knoxville flights
Burbank to Memphis flights
Burbank to Knoxville flights
San Jose to Knoxville flights
Santa Ana to Knoxville flights
Los Angeles to Chattanooga flights
San Luis Obispo to Nashville flights
Las Vegas to Memphis flights
Bakersfield to Nashville flights
Las Vegas to Knoxville flights
Santa Ana to Memphis flights
Reno to Nashville flights
Medford to Nashville flights
San Jose to Memphis flights
San Diego to Memphis flights
Ontario to Chattanooga flights
Oakland to Memphis flights
Santa Barbara to Nashville flights
Los Angeles to Blountville flights
San Diego to Chattanooga flights
Sacramento to Chattanooga flights
Santa Ana to Chattanooga flights
Long Beach to Memphis flights
Palm Springs to Knoxville flights
Sacramento to Memphis flights
San Francisco to Chattanooga flights
Oakland to Knoxville flights
San Francisco to Blountville flights
Reno to Memphis flights

Top 4 airlines flying from San Francisco to Knoxville

Discover the top 4 airlines that operate flights from San Francisco to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$149Average$226FlexibilityNo cancel feeOn-time62%
DeltaCheapest$286Average$483FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$308Average$478FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$326Average$577FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.