Knoxville

$99+ Cheap flights from San Diego to Knoxville (SAN - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — TYS
Apr 15 — Apr 221
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Cheapflights Tip: The best prices from San Diego to Knoxville McGhee Tyson are usually found in January or April, booked 21 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from San Diego to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 10, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$240
(Frontier)

One-way from

$99
(Frontier)

Popular in

December

Cheapest in

January

Average price

$383
Provider with most accurate pricing for San Diego-Knoxville McGhee Tyson flight deals.
Provider most trusted by Cheapflights users for San Diego-Knoxville McGhee Tyson flights.
From San Diego to Knoxville McGhee Tyson
One-way flight from San Diego to Knoxville McGhee Tyson
Highest demand for flights based on searches. 2% potential increase in price ($12 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from San Diego to Knoxville

Cheapest flights from San Diego to Knoxville
Explore the most affordable flight options available from San Diego to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2025.

This Frontier deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/176:25 amSAN - TYS
1 stop6h 16mFrontier
Sun 4/204:43 pmTYS - SAN
1 stop10h 31mFrontier
Deal found 4/9$240
This Mytrip deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/249:08 pmSAN - TYS
1 stop21h 51mMultiple Airlines
Mon 4/2810:53 amTYS - SAN
2 stops36h 01mMultiple Airlines
Deal found 4/9$246
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/510:39 pmSAN - TYS
1 stop9h 31mAmerican Airlines
Sat 5/107:50 pmTYS - SAN
1 stop7h 09mAmerican Airlines
Deal found 4/9$270
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/110:10 pmSAN - TYS
1 stop8h 53mDelta
Wed 8/137:30 amTYS - SAN
1 stop9h 29mDelta
Deal found 4/9$283
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2210:54 amSAN - TYS
2 stops9h 50mUnited Airlines
Sat 7/267:00 amTYS - SAN
1 stop7h 33mUnited Airlines
Deal found 4/9$296
This Alaska Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:15 amSAN - TYS
1 stop8h 16mAlaska Airlines
Sun 6/15:05 amTYS - SAN
2 stops10h 59mAlaska Airlines
Deal found 4/9$529

Cheapflights Fare Finder

Customize your flight search to find flights from San Diego to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2025.
Use the filters below to find and compare flights from San Diego to Knoxville that are best for you.

Fly from

San Diego

Fly to

Knoxville

Route

Depart

Return

Price

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Thu 4/24

6:15 am-4:25 pm

2 stops31h 10m

Knoxville McGhee Tyson

Mon 4/28

10:53 am-12:42 am

2 stops40h 49m

$240

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Mon 5/5

10:39 pm-11:10 am

1 stop9h 31m

Knoxville McGhee Tyson

Sat 5/10

7:50 pm-11:59 pm

1 stop7h 09m

$270

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Fri 8/1

10:10 pm-10:03 am

1 stop8h 53m

Knoxville McGhee Tyson

Wed 8/13

7:30 am-1:59 pm

1 stop9h 29m

$283

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Tue 7/22

10:54 am-11:44 pm

2 stops9h 50m

Knoxville McGhee Tyson

Sat 7/26

7:00 am-11:33 am

1 stop7h 33m

$296

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Thu 5/22

6:41 am-4:35 pm

1 stop6h 54m

Knoxville McGhee Tyson

Sun 5/25

5:30 pm-11:59 pm

1 stop9h 29m

$330

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Wed 5/28

6:15 am-5:31 pm

1 stop8h 16m

Knoxville McGhee Tyson

Sun 6/1

5:05 am-1:04 pm

2 stops10h 59m

$529

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Thu 4/17

6:25 am-3:41 pm

1 stop6h 16m

$99

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Thu 5/22

8:48 pm-1:24 pm

1 stop13h 36m

$111

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Sat 4/19

12:24 pm-11:29 pm

1 stop8h 05m

$115

San DiegoKnoxville

SAN - TYS

SANTYS

San Diego

Sat 5/31

6:15 am-5:30 pm

1 stop8h 15m

$139

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/9

Showing 1-10 of 12 results
1
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Compare providers for flights from San Diego to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Diego-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Diego-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Diego to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Knoxville

How far ahead should I book a flight from San Diego to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Knoxville. Price data was last updated on April 4, 2025.

Booking 21 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Diego to Knoxville?

Currently, January is the cheapest month in which you can book a flight from San Diego to Knoxville (average of $296). Flying from San Diego to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to TYS?

Find hourly flight availability from San Diego to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 10, 2025.

It’s typically best to fly out from San Diego to Knoxville at noon. Doing so could potentially save you 22% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from San Diego to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from San Diego to Knoxville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their San Diego to Knoxville flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 10, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Delta and United Airlines from San Diego to Knoxville by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
8.0
Very good

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Overall

8.0

Crew

8.5

Boarding

8.2

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from San Diego to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from San Diego to Knoxville round-trip?

    Cheapflights users have booked flights from San Diego to Knoxville round-trip from $240. Other airlines that can offer you cheap pricing are American Airlines, from $270, and Delta, from $289. These flights start at 43% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from San Diego to Knoxville one-way?

    One-way options have recently been found by users for as low as $99 on Frontier. Other airlines that offer cheap prices include American Airlines from $115 and Delta from $139 one-way.

  • Can I find deals for flights from San Diego to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Diego to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Knoxville.

  • Can I find deals for business class flights from San Diego to Knoxville?

    Yes. Cheapflights offers flight deals from San Diego to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from San Diego to Knoxville (average of $296). Flying from San Diego to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for San Diego to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from San Diego to Knoxville

Discover the top 5 airlines that operate flights from San Diego to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$84Average$238FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$255Average$442FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$264Average$458FlexibilityNo cancel feeOn-time71%
DeltaCheapest$275Average$396FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$503Average$798FlexibilityNo cancel feeOn-time75%

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