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$179+ Cheap flights from Portland, ME to Knoxville (PWM - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — TYS
Mar 31 — Apr 71
Mon 3/31
Mon 4/7
1 adult, Economy
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Cheapflights Tip: The best prices from Portland to Knoxville McGhee Tyson are usually found in December or September, booked 63 days in advance, depart on a Saturday or Wednesday and return on a Wednesday

Cheap flight deals from Portland to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 26, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$259
(American Airlines)

One-way from

$179
(American Airlines)

Popular in

May

Cheapest in

December

Average price

$483
Provider with most accurate pricing for Portland-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Portland-Knoxville McGhee Tyson flights.
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From Portland to Knoxville McGhee Tyson
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One-way flight from Portland to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 21% potential increase in price ($105 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Portland to Knoxville

Cheapest flights from Portland to Knoxville
Explore the most affordable flight options available from Portland to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/74:01 pmPWM - TYS
1 stop4h 54mAmerican Airlines
Sat 5/106:09 pmTYS - PWM
1 stop4h 56mAmerican Airlines
Deal found 3/25$259
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/117:26 pmPWM - TYS
1 stop4h 31mUnited Airlines
Mon 9/155:45 amTYS - PWM
1 stop4h 18mUnited Airlines
Deal found 3/24$271
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/95:30 amPWM - TYS
1 stop5h 42mDelta
Tue 4/156:44 amTYS - PWM
1 stop6h 28mDelta
Deal found 3/25$274
This Mytrip deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/316:18 pmPWM - TYS
2 stops29h 13mMultiple Airlines
Wed 4/27:15 amTYS - PWM
2 stops12h 17mMultiple Airlines
Deal found 3/24$580

Cheapflights Fare Finder

Customize your flight search to find flights from Portland to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

Fly from

Portland

Fly to

Knoxville

Route

Depart

Return

Price

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Wed 5/7

4:01 pm-8:55 pm

1 stop4h 54m

Knoxville McGhee Tyson

Sat 5/10

6:09 pm-11:05 pm

1 stop4h 56m

$259

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 9/11

7:26 pm-11:57 pm

1 stop4h 31m

Knoxville McGhee Tyson

Mon 9/15

5:45 am-10:03 am

1 stop4h 18m

$271

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Wed 4/9

5:30 am-11:12 am

1 stop5h 42m

Knoxville McGhee Tyson

Tue 4/15

6:44 am-1:12 pm

1 stop6h 28m

$274

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 7/3

12:32 pm-5:20 pm

2 stops28h 48m

Knoxville McGhee Tyson

Sun 7/6

8:00 am-11:35 am

2 stops27h 35m

$581

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Wed 5/7

12:08 pm-10:07 pm

1 stop9h 59m

$179

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 5/8

11:33 am-9:17 pm

2 stops9h 44m

$324

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Fri 9/5

11:47 am-10:28 am

3 stops22h 41m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Compare providers for flights from Portland to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland, Maine-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Knoxville

How far ahead should I book a flight from Portland, Maine to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Knoxville. Price data was last updated on March 21, 2025.

The best time to book flights from Portland, Maine to Knoxville is 59 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland, Maine to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Knoxville (average of $295). Flying from Portland, Maine to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to TYS?

Find hourly flight availability from Portland to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2025.

It’s optimal to fly from Portland, Maine to Knoxville at noon. By choosing this option you can save up to 10% on the cost of your flight, compared to a flight in the morning.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 26, 2025.
See what other customers who have flown with Delta, United Airlines and American Airlines from Portland to Knoxville have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,891 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,891 reviews
Delta
8.0
Very good
7,891 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,608 reviews
Delta
8.0
Very good
7,891 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,891 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Portland to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Portland, Maine to Knoxville round-trip?

    Cheapflights users have booked flights from Portland, Maine to Knoxville round-trip from $259. Other airlines that can offer you cheap pricing are United Airlines, from $271, and Delta, from $274. You may be able to fly from Portland, Maine to Knoxville for 32% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Portland, Maine to Knoxville one-way?

    $179 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $324 and $329, respectively.

  • Can I find deals for flights from Portland to Knoxville that include hotel bookings?

    Yes. In addition to deals on Portland to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Knoxville.

  • Can I find deals for business class flights from Portland to Knoxville?

    Yes. Cheapflights offers flight deals from Portland to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Portland, Maine to Knoxville (average of $295). Flying from Portland, Maine to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 3 airlines flying from Portland to Knoxville

Discover the top 3 airlines that operate flights from Portland to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$229Average$359FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$343FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$363FlexibilityNo cancel feeOn-time69%
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