What are the cheapest airlines to fly from Orange County to Knoxville one-way?

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $117. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Orange County to Knoxville for a low price.

What are the most popular airlines that fly from Orange County to Knoxville?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Orange County to Knoxville.

How far in advance should I book a flight from Orange County to Knoxville?

To save on the cost of your flight from Orange County to Knoxville, book at least 58 days before your planned departure. Booking around this time can save you about 45% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $453 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $628.

What is the cheapest month to fly from Orange County to Knoxville?

The best pricing can be found in the month of September. Prices to Knoxville from Orange County average $519. You can even find prices in September for less than $519, as users have found deals to Knoxville from as low as $238. The month of January appears to be one of the more expensive times to travel to Knoxville from Orange County. Flying in the targeted month can save you up to 37%.

What airport do you fly into for flights to Knoxville from Orange County?

Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Orange County. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

Can I find deals for flights from Orange County to Knoxville that include hotel bookings?

Yes. In addition to deals on Orange County to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Orange County to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Orange County to Knoxville.

Can I find deals for business class flights from Orange County to Knoxville?

Yes. Cheapflights offers flight deals from Orange County to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$106+ Flights from Orange County to Knoxville

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Cheap flight deals from Orange County to Knoxville

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$251 (United Airlines)
One-way from	$106 (Mytrip)
Popular in	January
Cheapest in	September
Average price	$547

Provider with most accurate pricing for Los Angeles-Knoxville McGhee Tyson flight deals.

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Provider most trusted by Cheapflights users for Los Angeles-Knoxville McGhee Tyson flights.

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From Orange County to Knoxville McGhee Tyson

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One-way flight from Orange County to Knoxville McGhee Tyson

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Highest demand for flights based on searches. 19% potential increase in price ($123 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Find flight deals from Orange County to Knoxville

Cheapest flights from Orange County to Knoxville
Explore the most affordable flight options available from Orange County to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

Wed 5/2112:01 pmSNA - TYS

1 stop25h 34mFrontier

Sun 5/255:30 pmTYS - SNA

1 stop20h 41mFrontier

Deal found 4/17

$231

Tue 7/1511:28 amSNA - TYS

1 stop7h 06mAmerican Airlines

Sat 7/262:57 pmTYS - SNA

1 stop9h 25mAmerican Airlines

Deal found 4/17

$251

Thu 5/224:27 pmSNA - TYS

1 stop17h 57mMultiple Airlines

Sun 5/257:30 amTYS - SNA

2 stops39h 04mMultiple Airlines

Deal found 4/17

$282

Tue 7/155:05 pmSNA - TYS

2 stops13h 58mDelta

Sat 7/265:30 amTYS - SNA

2 stops13h 47mDelta

Deal found 4/17

$318

Fri 5/210:50 amSNA - TYS

1 stop8h 55mUnited Airlines

Tue 5/64:14 pmTYS - SNA

1 stop7h 41mUnited Airlines

Deal found 4/17

$339

Mon 11/37:00 amSNA - TYS

2 stops25h 19mAlaska Airlines

Fri 11/74:33 pmTYS - SNA

2 stops19h 17mAlaska Airlines

Deal found 4/17

$499

Wed 6/255:07 pmLGB - TYS

2 stops13h 46mDelta

Mon 6/308:35 amTYS - LGB

2 stops16h 06mDelta

Deal found 4/17

$675

Best flights from Orange County to Knoxville
Discover carefully curated flight deals from Orange County to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2025.

Sat 5/1010:27 amSNA - TYS

1 stop6h 39mUnited Airlines

Wed 5/144:14 pmTYS - SNA

1 stop8h 46mUnited Airlines

Deal found 4/16

$251

Sat 5/106:45 amSNA - TYS

1 stop7h 46mAmerican Airlines

Thu 5/155:05 amTYS - SNA

1 stop10h 34mAmerican Airlines

Deal found 4/16

$270

Tue 5/1312:17 pmSNA - TYS

1 stop8h 34mDelta

Wed 5/142:04 pmTYS - SNA

1 stop6h 28mDelta

Deal found 4/16

$277

Sun 5/187:58 pmSNA - TYS

1 stop14h 46mMultiple Airlines

Wed 5/217:10 amTYS - SNA

2 stops17h 07mMultiple Airlines

Deal found 4/16

$300

Fri 5/98:05 amSNA - TYS

2 stops11h 02mAlaska Airlines

Mon 5/127:50 pmTYS - SNA

2 stops20h 17mAlaska Airlines

Deal found 4/16

$389

Sat 6/1412:01 pmSNA - TYS

1 stop25h 28mFrontier

Thu 6/195:25 pmTYS - SNA

1 stop20h 51mFrontier

Deal found 4/17

$513

Wed 6/255:07 pmLGB - TYS

2 stops13h 46mDelta

Mon 6/308:35 amTYS - LGB

2 stops16h 06mDelta

Deal found 4/17

$675

Last-minute flights from Orange County to Knoxville
Discover last-minute flight deals from Orange County to Knoxville. Data last updated April 17, 2025 and is based on user searches.

Thu 4/175:00 pmLGB - TYS

2 stops13h 21mDelta

Sun 4/209:30 amTYS - LGB

2 stops9h 46mDelta

Deal found 4/17

$3,020

Wed 4/237:46 amSNA - TYS

2 stops12h 44mAlaska Airlines

Mon 4/285:24 amTYS - SNA

2 stops14h 11mAlaska Airlines

Deal found 4/17

$664

Thu 4/2411:34 amSNA - TYS

1 stop8h 56mAmerican Airlines

Mon 4/285:24 amTYS - SNA

1 stop7h 10mAmerican Airlines

Deal found 4/17

$419

Thu 4/246:50 amSNA - TYS

1 stop12h 40mUnited Airlines

Thu 5/14:14 pmTYS - SNA

1 stop8h 46mUnited Airlines

Deal found 4/17

$622

Fri 5/98:05 amSNA - TYS

2 stops11h 02mAlaska Airlines

Mon 5/127:50 pmTYS - SNA

2 stops20h 17mAlaska Airlines

Deal found 4/16

$389

Sat 5/1010:27 amSNA - TYS

1 stop6h 39mUnited Airlines

Wed 5/144:14 pmTYS - SNA

1 stop8h 46mUnited Airlines

Deal found 4/16

$251

Sat 5/106:45 amSNA - TYS

1 stop7h 46mAmerican Airlines

Thu 5/155:05 amTYS - SNA

1 stop10h 34mAmerican Airlines

Deal found 4/16

$270

Tue 5/1312:17 pmSNA - TYS

1 stop8h 34mDelta

Wed 5/142:04 pmTYS - SNA

1 stop6h 28mDelta

Deal found 4/16

$277

Sun 5/187:58 pmSNA - TYS

1 stop14h 46mMultiple Airlines

Wed 5/217:10 amTYS - SNA

2 stops17h 07mMultiple Airlines

Deal found 4/16

$300

One-way flights from Orange County to Knoxville
Search for one-way flight options from Orange County to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 17, 2025.

Thu 5/84:27 pmSNA - TYS

1 stop26h 32mMultiple Airlines

Deal found 4/15

$106

Wed 5/2112:01 pmSNA - TYS

1 stop25h 34mFrontier

Deal found 4/17

$117

Wed 5/216:45 amSNA - TYS

2 stops7h 46mAmerican Airlines

Deal found 4/17

$205

Wed 4/235:10 pmSNA - TYS

2 stops13h 11mDelta

Deal found 4/16

$206

Wed 4/3010:49 amSNA - TYS

1 stop8h 33mUnited Airlines

Deal found 4/16

$250

Thu 4/246:45 amSNA - TYS

2 stops13h 45mAlaska Airlines

Deal found 4/16

$450

Wed 4/235:00 pmLGB - TYS

2 stops13h 21mDelta

Deal found 4/16

$504

Cheapflights Fare Finder

Use the filters below to find and compare flights from Orange County to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sat 5/10

10:27 am-8:06 pm

1 stop6h 39m

Knoxville McGhee Tyson

Wed 5/14

4:14 pm-10:00 pm

1 stop8h 46m

$251

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sat 5/10

6:45 am-5:31 pm

1 stop7h 46m

Knoxville McGhee Tyson

Thu 5/15

5:05 am-12:39 pm

1 stop10h 34m

$270

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Tue 5/13

12:17 pm-11:51 pm

1 stop8h 34m

Knoxville McGhee Tyson

Wed 5/14

2:04 pm-5:32 pm

1 stop6h 28m

$277

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sun 5/18

7:58 pm-1:44 pm

1 stop14h 46m

Knoxville McGhee Tyson

Wed 5/21

7:10 am-9:17 pm

2 stops17h 07m

$300

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Fri 5/9

8:05 am-10:07 pm

2 stops11h 02m

Knoxville McGhee Tyson

Mon 5/12

7:50 pm-1:07 pm

2 stops20h 17m

$389

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Sat 6/14

12:01 pm-4:29 pm

1 stop25h 28m

Knoxville McGhee Tyson

Thu 6/19

5:25 pm-11:16 am

1 stop20h 51m

$513

Long BeachKnoxville

LGB - TYS

LGBTYS

Long Beach Municipal

Wed 6/25

5:07 pm-9:53 am

2 stops13h 46m

Knoxville McGhee Tyson

Mon 6/30

8:35 am-9:41 pm

2 stops16h 06m

$675

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Thu 5/8

4:27 pm-9:59 pm

1 stop26h 32m

$106

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Wed 5/21

12:01 pm-4:35 pm

1 stop25h 34m

$117

Santa AnaKnoxville

SNA - TYS

SNATYS

Santa Ana J. Wayne/Orange Cnty

Wed 5/21

6:45 am-5:31 pm

2 stops7h 46m

$205

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 14 results

Best time to book a flight from Orange County to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Orange County with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Orange County to Knoxville

What is the cheapest month to book a flight from Orange County to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Orange County to Knoxville (average of $296). Flying from Orange County to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KFI to TYS?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Orange County to Knoxville as you normally would.

Rainfall in Knoxville by month

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get a feel of what it's like to fly with Alaska Airlines, Delta and United Airlines from Orange County to Knoxville by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,887 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Alaska Airlines

8.0

Very good

9,887 reviews

Alaska Airlines

8.0

Very good

9,887 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Delta

8.0

Very good

7,916 reviews

Alaska Airlines

8.0

Very good

9,887 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

United Airlines

7.4

Good

8,667 reviews

Alaska Airlines

8.0

Very good

9,887 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

American Airlines

7.2

Good

10,000 reviews

Alaska Airlines

8.0

Very good

9,887 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Frontier

6.0

Okay

3,281 reviews

Alaska Airlines

8.0

Very good

9,887 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

What airport do you fly into for flights to Knoxville from Orange County?
Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Orange County. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.
What are the cheapest airlines to fly from Orange County to Knoxville one-way?
The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $117. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Orange County to Knoxville for a low price.
Can I find deals for flights from Orange County to Knoxville that include hotel bookings?
Yes. In addition to deals on Orange County to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Orange County to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Orange County to Knoxville.
Can I find deals for business class flights from Orange County to Knoxville?
Yes. Cheapflights offers flight deals from Orange County to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Orange County to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Orange County to Knoxville (average of $296). Flying from Orange County to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Morristown

Cherokee

Corbin

Maryville

Oak Ridge

Alcoa

Murphy

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Orange County to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$228	Average$505	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$261	Average$433	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$276	Average$397	FlexibilityNo cancel fee	On-timeN/A

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$106+ Cheap flights from Orange County to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Orange County to Knoxville with Cheapflights

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Cheap flight deals from Orange County to Knoxville

Keep the following information in mind while searching for Orange County to Knoxville flight deals. Data was last updated April 17, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Orange County to Knoxville

Cheapest flights from Orange County to KnoxvilleExplore the most affordable flight options available from Orange County to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

Explore the most affordable flight options available from Orange County to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Orange County to Knoxville that are best for you.

Best time to book a flight from Orange County to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Orange County with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Orange County to Knoxville

What is the cheapest month to book a flight from Orange County to Knoxville?

What is the cheapest time of day to fly from KFI to TYS?

Find hourly flight availability from Orange County to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

Reviews of airlines servicing Knoxville

Get a feel of what it's like to fly with Alaska Airlines, Delta and United Airlines from Orange County to Knoxville by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Orange County to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Knoxville from Orange County?

What are the cheapest airlines to fly from Orange County to Knoxville one-way?

Can I find deals for flights from Orange County to Knoxville that include hotel bookings?

How can I find direct flights from Orange County to Knoxville?

Can I find deals for business class flights from Orange County to Knoxville?

What is the cheapest month to book a flight from Orange County to Knoxville?

Traveling to a place near Orange County?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Orange County to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Orange County to Knoxville

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Cheapest flights from Orange County to Knoxville
Explore the most affordable flight options available from Orange County to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.