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Knoxville

$96+ Cheap flights from Ohio to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — TYS
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Ohio to Knoxville

Keep the following information in mind while searching for Ohio to Knoxville flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$198
(Mytrip)

One-way from

$96
(Mytrip)

Popular in

March

Cheapest in

February

Average price

$383
Provider with most accurate pricing for Cleveland Hopkins Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Knoxville McGhee Tyson flights.
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From Ohio to Knoxville McGhee Tyson
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One-way flight from Ohio to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Ohio to Knoxville

Cheapest flights from Ohio to Knoxville
Explore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Mytrip deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/146:15 amCVG - TYS
1 stop15h 00mAllegiant Air
Fri 4/184:12 pmTYS - CVG
1 stop19h 59mAllegiant Air
Deal found 3/29$198
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/227:15 amCMH - TYS
1 stop3h 52mDelta
Wed 7/305:30 amTYS - CMH
1 stop3h 29mDelta
Deal found 3/30$199
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/196:20 pmPIT - TYS
1 stop5h 28mDelta
Sat 4/265:30 amTYS - PIT
1 stop4h 38mDelta
Deal found 3/29$199
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/196:53 pmCLE - TYS
1 stop4h 52mAmerican Airlines
Sat 4/267:23 amTYS - CLE
1 stop6h 39mAmerican Airlines
Deal found 3/31$199
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2811:55 amCMH - TYS
1 stop5h 17mAmerican Airlines
Sat 7/56:05 pmTYS - CMH
1 stop3h 59mAmerican Airlines
Deal found 3/30$203
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/299:00 amCLE - TYS
1 stop4h 22mUnited Airlines
Tue 5/65:50 amTYS - CLE
2 stops8h 53mUnited Airlines
Deal found 3/30$204
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/145:15 amCMH - TYS
1 stop12h 44mMultiple Airlines
Fri 4/181:29 pmTYS - CMH
1 stop21h 17mMultiple Airlines
Deal found 3/30$206
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/88:39 pmCLE - TYS
1 stop17h 24mMultiple Airlines
Fri 4/114:12 pmTYS - CLE
1 stop26h 01mMultiple Airlines
Deal found 3/30$217
This Mytrip deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/289:09 pmDTW - TYS
2 stops22h 36mMultiple Airlines
Sat 5/318:10 amTYS - DTW
2 stops11h 51mMultiple Airlines
Deal found 3/29$218
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/257:56 pmPIT - TYS
1 stop15h 59mMultiple Airlines
Sun 9/281:20 pmTYS - PIT
1 stop25h 09mMultiple Airlines
Deal found 3/30$221
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/214:20 pmCMH - TYS
1 stop6h 45mUnited Airlines
Mon 6/235:45 amTYS - CMH
1 stop3h 47mUnited Airlines
Deal found 3/31$223
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/202:35 pmCLE - TYS
1 stop3h 42mDelta
Sun 8/247:25 pmTYS - CLE
1 stop3h 43mDelta
Deal found 3/30$224

Cheapflights Fare Finder

Customize your flight search to find flights from Ohio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Ohio to Knoxville that are best for you.

Fly from

Ohio

Fly to

Knoxville

Route

Depart

Return

Price

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Mon 4/14

6:15 am-9:15 pm

1 stop15h 00m

Knoxville McGhee Tyson

Fri 4/18

4:12 pm-12:11 pm

1 stop19h 59m

$198

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Tue 7/22

7:15 am-11:07 am

1 stop3h 52m

Knoxville McGhee Tyson

Wed 7/30

5:30 am-8:59 am

1 stop3h 29m

$199

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sat 4/19

6:53 pm-11:45 pm

1 stop4h 52m

Knoxville McGhee Tyson

Sat 4/26

7:23 am-2:02 pm

1 stop6h 39m

$199

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sat 4/19

6:20 pm-11:48 pm

1 stop5h 28m

Knoxville McGhee Tyson

Sun 4/20

7:48 am-1:27 pm

1 stop5h 39m

$199

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Sat 6/28

11:55 am-5:12 pm

1 stop5h 17m

Knoxville McGhee Tyson

Sat 7/5

6:05 pm-10:04 pm

1 stop3h 59m

$203

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Tue 4/29

9:00 am-1:22 pm

1 stop4h 22m

Knoxville McGhee Tyson

Tue 5/6

5:50 am-2:43 pm

2 stops8h 53m

$204

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Mon 4/14

5:15 am-5:59 pm

1 stop12h 44m

Knoxville McGhee Tyson

Fri 4/18

1:29 pm-10:46 am

1 stop21h 17m

$206

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Tue 4/8

8:39 pm-2:03 pm

1 stop17h 24m

Knoxville McGhee Tyson

Fri 4/11

4:12 pm-6:13 pm

1 stop26h 01m

$217

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 5/28

9:09 pm-7:45 pm

2 stops22h 36m

Knoxville McGhee Tyson

Sat 5/31

8:10 am-8:01 pm

2 stops11h 51m

$218

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Thu 4/17

6:00 am-9:21 am

1 stop3h 21m

Knoxville McGhee Tyson

Sun 4/20

5:30 am-9:34 am

1 stop4h 04m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 46 results
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Best time to book a flight from Ohio to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Knoxville

What is the cheapest month to book a flight from Ohio to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $296). Flying from Ohio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to TYS?

Find hourly flight availability from Ohio to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Ohio to Knoxville as you normally would.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 31, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from Ohio to Knoxville. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,614 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
731 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,276 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Ohio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Ohio?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Ohio.

  • What are the cheapest airlines to fly from Ohio to Knoxville one-way?

    The cheapest airlines for a one-way flight from Ohio to Knoxville are Frontier ($96), Delta ($100), and American Airlines ($100).

  • What are the most popular routes from Ohio to Knoxville?

    Most travelers choose Detroit Metropolitan Wayne County - Knoxville McGhee Tyson, Cleveland Hopkins Intl - Knoxville McGhee Tyson or Pittsburgh - Knoxville McGhee Tyson when deciding on the best route from Ohio to Knoxville.

  • Can I find deals for flights from Ohio to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ohio to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Knoxville.

  • Can I find deals for business class flights from Ohio to Knoxville?

    Yes. Cheapflights offers flight deals from Ohio to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $296). Flying from Ohio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Ohio?

Book flights to Ohio if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Ohio to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Ohio to Knoxville

Discover the top 3 airlines that operate flights from Ohio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$303FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$284FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$198Average$315FlexibilityNo cancel feeOn-time69%
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