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$77+ Cheap flights from Ohio to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — TYS
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Ohio to Knoxville

Keep the following information in mind while searching for Ohio to Knoxville flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$175
(Mytrip)

One-way from

$90
(Mytrip)

Popular in

March

Cheapest in

February

Average price

$238
Provider with most accurate pricing for Cleveland Hopkins Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Knoxville McGhee Tyson flights.
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From Ohio to Knoxville McGhee Tyson
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One-way flight from Ohio to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 5% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Ohio to Knoxville

Cheapest flights from Ohio to Knoxville
Explore the most affordable flight options available from Ohio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/26:00 amCLE - TYS
1 stop8h 03mMultiple Airlines
Thu 4/36:00 amTYS - CLE
1 stop13h 34mMultiple Airlines
Deal found 2/20$175
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/165:00 amDTW - TYS
1 stop12h 53mMultiple Airlines
Sat 4/196:00 amTYS - DTW
1 stop15h 12mMultiple Airlines
Deal found 2/19$192
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:30 amCVG - TYS
1 stop11h 24mAllegiant Air
Mon 3/103:18 pmTYS - CVG
1 stop20h 56mAllegiant Air
Deal found 2/19$194
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/23:39 pmCMH - TYS
1 stop5h 48mAmerican Airlines
Sat 4/57:49 amTYS - CMH
1 stop4h 48mAmerican Airlines
Deal found 2/20$199
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/56:00 amPIT - TYS
1 stop3h 40mDelta
Tue 4/86:45 amTYS - PIT
1 stop5h 27mDelta
Deal found 2/19$199
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/105:13 pmCLE - TYS
1 stop6h 07mAmerican Airlines
Sat 5/176:09 pmTYS - CLE
1 stop6h 30mAmerican Airlines
Deal found 2/18$199
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/56:03 pmPIT - TYS
1 stop4h 19mUnited Airlines
Tue 4/87:00 amTYS - PIT
2 stops7h 00mUnited Airlines
Deal found 2/19$205
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/36:55 pmCLE - TYS
1 stop4h 47mDelta
Tue 4/85:45 amTYS - CLE
1 stop6h 14mDelta
Deal found 2/18$214
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/76:30 amPIT - TYS
1 stop5h 30mMultiple Airlines
Tue 3/111:35 pmTYS - PIT
1 stop27h 34mMultiple Airlines
Deal found 2/19$216
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/175:35 amCVG - TYS
1 stop5h 03mAmerican Airlines
Sun 4/206:59 amTYS - CVG
1 stop5h 57mAmerican Airlines
Deal found 2/19$219
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:30 amCVG - TYS
2 stops35h 05mMultiple Airlines
Mon 3/103:18 pmTYS - CVG
1 stop20h 56mMultiple Airlines
Deal found 2/19$235
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/124:24 pmCLE - TYS
1 stop5h 58mUnited Airlines
Sun 4/137:00 amTYS - CLE
1 stop6h 06mUnited Airlines
Deal found 2/19$236

Find flights from Ohio to Knoxville within your budget

Customize your flight search to find flights from Ohio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Ohio

Fly to

Knoxville

Route

Depart

Return

Price

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Wed 4/2

6:00 am-2:03 pm

1 stop8h 03m

Knoxville McGhee Tyson

Thu 4/3

6:00 am-7:34 pm

1 stop13h 34m

$175

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Wed 4/16

5:00 am-5:53 pm

1 stop12h 53m

Knoxville McGhee Tyson

Sat 4/19

6:00 am-9:12 pm

1 stop15h 12m

$192

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Thu 3/6

6:30 am-5:54 pm

1 stop11h 24m

Knoxville McGhee Tyson

Mon 3/10

3:18 pm-12:14 pm

1 stop20h 56m

$194

ColumbusKnoxville

CMH - TYS

CMHTYS

Columbus

Wed 4/2

3:39 pm-9:27 pm

1 stop5h 48m

Knoxville McGhee Tyson

Sat 4/5

7:49 am-12:37 pm

1 stop4h 48m

$199

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sat 4/5

6:00 am-9:40 am

1 stop3h 40m

Knoxville McGhee Tyson

Tue 4/8

6:45 am-12:12 pm

1 stop5h 27m

$199

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Sat 5/10

5:13 pm-11:20 pm

1 stop6h 07m

Knoxville McGhee Tyson

Sat 5/17

7:50 pm-12:30 am

1 stop4h 40m

$199

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Sat 4/5

6:03 pm-10:22 pm

1 stop4h 19m

Knoxville McGhee Tyson

Tue 4/8

7:00 am-2:00 pm

2 stops7h 00m

$205

ClevelandKnoxville

CLE - TYS

CLETYS

Cleveland Hopkins Intl

Thu 4/3

6:55 pm-11:42 pm

1 stop4h 47m

Knoxville McGhee Tyson

Tue 4/8

5:45 am-11:59 am

1 stop6h 14m

$214

PittsburghKnoxville

PIT - TYS

PITTYS

Pittsburgh

Fri 3/7

6:30 am-12:00 pm

1 stop5h 30m

Knoxville McGhee Tyson

Tue 3/11

1:35 pm-5:09 pm

1 stop27h 34m

$216

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Thu 4/17

5:35 am-10:38 am

1 stop5h 03m

Knoxville McGhee Tyson

Sun 4/20

6:59 am-12:56 pm

1 stop5h 57m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 44 results
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Best time to book a flight from Ohio to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Ohio to Knoxville

Get recent, data-driven insights about flights from Ohio to Knoxville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Ohio to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $296). Flying from Ohio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from OH to TYS?

Find hourly flight availability from Ohio to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Ohio to Knoxville as you normally would.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 20, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from Ohio to Knoxville. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,220 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,766 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.3
Good
765 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

8.0

Overall

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Ohio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Ohio?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Ohio.

  • What are the cheapest airlines to fly from Ohio to Knoxville one-way?

    The cheapest airlines for a one-way flight from Ohio to Knoxville are Delta ($100), Allegiant Air ($109), and United Airlines ($135).

  • What are the most popular routes from Ohio to Knoxville?

    Most travelers choose Detroit Metropolitan Wayne County - Knoxville McGhee Tyson, Cleveland Hopkins Intl - Knoxville McGhee Tyson or Pittsburgh - Knoxville McGhee Tyson when deciding on the best route from Ohio to Knoxville.

  • Can I find deals for flights from Ohio to Knoxville that include hotel bookings?

    Yes. In addition to deals on Ohio to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Knoxville.

  • Can I find deals for business class flights from Ohio to Knoxville?

    Yes. Cheapflights offers flight deals from Ohio to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ohio to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Ohio to Knoxville (average of $296). Flying from Ohio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Ohio?

Book flights to Ohio if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Ohio to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Ohio to Knoxville

Discover the top 3 airlines that operate flights from Ohio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$197Average$313FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$303FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$198Average$345FlexibilityNo cancel feeOn-time69%
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