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Knoxville

$100+ Cheap flights from North Carolina to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — TYS
Apr 21 — Apr 281
Mon 4/21
Mon 4/28
1 adult, Economy
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Cheap flight deals from North Carolina to Knoxville

Keep the following information in mind while searching for North Carolina to Knoxville flight deals. Data was last updated April 16, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$205
(Mytrip)

One-way from

$100
(American Airlines)

Popular in

June

Cheapest in

May

Average price

$506

Good one-way deal

$320 or less
Provider with most accurate pricing for Charlotte Douglas-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Knoxville McGhee Tyson flights.
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From North Carolina to Knoxville McGhee Tyson
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One-way flight from North Carolina to Knoxville McGhee Tyson
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High demand for flights, 2% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a one-way flight from North Carolina to Knoxville McGhee Tyson.
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Find flight deals from North Carolina to Knoxville

Cheapest flights from North Carolina to Knoxville
Explore the most affordable flight options available from North Carolina to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 16, 2025.

This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/29:19 pmORF - TYS
1 stop23h 49mAllegiant Air
Sun 5/412:34 pmTYS - ORF
1 stop26h 19mAllegiant Air
Deal found 4/15$205
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2412:50 pmRDU - TYS
1 stop4h 31mAmerican Airlines
Tue 5/277:54 pmTYS - RDU
1 stop4h 04mAmerican Airlines
Deal found 4/15$209
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/305:25 amRDU - TYS
1 stop5h 58mDelta
Fri 6/65:45 amTYS - RDU
1 stop5h 33mDelta
Deal found 4/14$218
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/211:45 amRDU - TYS
1 stop10h 33mMultiple Airlines
Sun 5/43:52 pmTYS - RDU
1 stop18h 48mMultiple Airlines
Deal found 4/16$222
This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/26:58 amCLT - TYS
1 stop15h 20mMultiple Airlines
Mon 5/510:00 amTYS - CLT
1 stop24h 12mMultiple Airlines
Deal found 4/15$225
This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/99:19 pmORF - TYS
1 stop23h 53mMultiple Airlines
Mon 5/198:00 amTYS - ORF
1 stop26h 29mMultiple Airlines
Deal found 4/15$226
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/37:00 amORF - TYS
1 stop4h 07mDelta
Mon 9/87:15 pmTYS - ORF
1 stop3h 35mDelta
Deal found 4/16$229
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/96:00 amMYR - TYS
1 stop3h 40mDelta
Wed 5/145:45 amTYS - MYR
1 stop4h 23mDelta
Deal found 4/16$229
This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/157:25 pmMYR - TYS
1 stop26h 14mMultiple Airlines
Sun 5/188:59 pmTYS - MYR
1 stop24h 06mMultiple Airlines
Deal found 4/15$230
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/296:14 pmILM - TYS
1 stop5h 31mAmerican Airlines
Tue 5/65:58 pmTYS - ILM
1 stop6h 00mAmerican Airlines
Deal found 4/15$234
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:00 amOAJ - TYS
1 stop3h 24mAmerican Airlines
Mon 6/27:54 pmTYS - OAJ
1 stop4h 11mAmerican Airlines
Deal found 4/16$249
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2712:06 pmILM - TYS
2 stops20h 11mMultiple Airlines
Sun 6/299:08 pmTYS - ILM
1 stop26h 42mMultiple Airlines
Deal found 4/16$277

Cheapflights Fare Finder

Customize your flight search to find flights from North Carolina to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 16, 2025.
Use the filters below to find and compare flights from North Carolina to Knoxville that are best for you.

Fly from

North Carolina

Fly to

Knoxville

Route

Depart

Return

Price

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

Fri 5/2

9:19 pm-9:08 pm

1 stop23h 49m

Knoxville McGhee Tyson

Sun 5/4

12:34 pm-2:53 pm

1 stop26h 19m

$205

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Sat 5/31

12:50 pm-5:21 pm

1 stop4h 31m

Knoxville McGhee Tyson

Sat 6/7

8:13 pm-11:59 pm

1 stop3h 46m

$209

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Fri 5/2

11:45 am-10:18 pm

1 stop10h 33m

Knoxville McGhee Tyson

Sun 5/4

3:52 pm-10:40 am

1 stop18h 48m

$222

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

Fri 5/2

6:58 am-10:18 pm

1 stop15h 20m

Knoxville McGhee Tyson

Mon 5/5

10:00 am-10:12 am

1 stop24h 12m

$225

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

Fri 5/9

9:19 pm-9:12 pm

1 stop23h 53m

Knoxville McGhee Tyson

Mon 5/19

8:00 am-10:29 am

1 stop26h 29m

$226

NorfolkKnoxville

ORF - TYS

ORFTYS

Norfolk

Wed 9/3

7:00 am-11:07 am

1 stop4h 07m

Knoxville McGhee Tyson

Mon 9/8

7:15 pm-10:50 pm

1 stop3h 35m

$229

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Wed 4/30

5:20 am-9:21 am

1 stop4h 01m

Knoxville McGhee Tyson

Sun 5/4

5:30 am-8:54 am

1 stop3h 24m

$229

Myrtle BeachKnoxville

MYR - TYS

MYRTYS

Myrtle Beach Intl

Fri 5/9

6:00 am-9:40 am

1 stop3h 40m

Knoxville McGhee Tyson

Wed 5/14

5:45 am-10:08 am

1 stop4h 23m

$229

Myrtle BeachKnoxville

MYR - TYS

MYRTYS

Myrtle Beach Intl

Thu 5/15

7:25 pm-9:39 pm

1 stop26h 14m

Knoxville McGhee Tyson

Sun 5/18

8:59 pm-9:05 pm

1 stop24h 06m

$230

WilmingtonKnoxville

ILM - TYS

ILMTYS

Wilmington New Hanover County

Tue 4/29

6:14 pm-11:45 pm

1 stop5h 31m

Knoxville McGhee Tyson

Tue 5/6

5:58 pm-11:58 pm

1 stop6h 00m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 36 results
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Best time to book a flight from North Carolina to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to Knoxville

What is the cheapest month to book a flight from North Carolina to Knoxville?

Currently, January is the cheapest month in which you can book a flight from North Carolina to Knoxville (average of $296). Flying from North Carolina to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from NC to TYS?

Find hourly flight availability from North Carolina to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 16, 2025.

When flying from North Carolina to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 16, 2025.
Read through reviews of airlines operating flights from North Carolina to Knoxville, such as Delta, United Airlines and Allegiant Air. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,916 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,665 reviews
Delta
8.0
Very good
7,916 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,916 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.2

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from North Carolina to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from North Carolina?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from North Carolina. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines to fly from North Carolina to Knoxville one-way?

    The cheapest airlines for a one-way flight from North Carolina to Knoxville are American Airlines ($100), Allegiant Air ($101), and Delta ($126).

  • What are the most popular routes from North Carolina to Knoxville?

    The most popular flight routes from North Carolina to Knoxville are Norfolk - Knoxville McGhee Tyson, Raleigh-Durham - Knoxville McGhee Tyson and Myrtle Beach Intl - Knoxville McGhee Tyson.

  • Can I find deals for flights from North Carolina to Knoxville that include hotel bookings?

    Yes. In addition to deals on North Carolina to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to Knoxville.

  • Can I find deals for business class flights from North Carolina to Knoxville?

    Yes. Cheapflights offers flight deals from North Carolina to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from North Carolina to Knoxville (average of $296). Flying from North Carolina to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near North Carolina?

Book flights to North Carolina if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for North Carolina to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from North Carolina to Knoxville

Discover the top 3 airlines that operate flights from North Carolina to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$311FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$217Average$444FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$223Average$328FlexibilityNo cancel feeOn-time69%

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