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$369+ Cheap flights from Medford to Knoxville (MFR - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/18. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — TYS
Apr 9 — Apr 161
Wed 4/9
Wed 4/16
1 adult, Economy
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Cheap flight deals from Medford to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$369
(United Airlines)

Popular in

June

Cheapest in

December

Average price

$692
Provider with most accurate pricing for Medford-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Medford-Knoxville McGhee Tyson flights.
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From Medford to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 19% potential increase in price ($155 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Medford to Knoxville

Cheapest flights from Medford to Knoxville
Explore the most affordable flight options available from Medford to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2025.

This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/185:00 amMFR - TYS
1 stop6h 44mUnited Airlines
Tue 4/224:31 pmTYS - MFR
1 stop7h 55mUnited Airlines
Deal found 4/3$369
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/185:30 pmMFR - TYS
2 stops13h 12mDelta
Tue 4/2212:55 pmTYS - MFR
2 stops13h 46mDelta
Deal found 4/3$379
This Mytrip deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/224:07 pmMFR - TYS
2 stops18h 17mMultiple Airlines
Thu 5/296:00 amTYS - MFR
2 stops12h 22mMultiple Airlines
Deal found 4/3$393

Cheapflights Fare Finder

Customize your flight search to find flights from Medford to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
Use the filters below to find and compare flights from Medford to Knoxville that are best for you.

Fly from

Medford

Fly to

Knoxville

Route

Depart

Return

Price

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Fri 4/18

5:00 am-2:44 pm

1 stop6h 44m

Knoxville McGhee Tyson

Tue 4/22

4:31 pm-9:26 pm

1 stop7h 55m

$369

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Fri 4/18

5:30 pm-9:42 am

2 stops13h 12m

Knoxville McGhee Tyson

Tue 4/22

12:55 pm-11:41 pm

2 stops13h 46m

$379

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Thu 5/22

4:07 pm-1:24 pm

2 stops18h 17m

Knoxville McGhee Tyson

Thu 5/29

6:00 am-3:22 pm

2 stops12h 22m

$393

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/3

Compare providers for flights from Medford to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Knoxville

What is the cheapest month to book a flight from Medford to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Medford to Knoxville (average of $296). Flying from Medford to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 4, 2025.
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,618 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Overall

8.0

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Medford to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Medford to Knoxville round-trip?

    United Airlines, at $369, was found to be the cheapest airline from Medford to Knoxville. An alternate airline flying to your destination would be Delta. These flights start at 43% lower than the current average price 3 months from now.

  • Can I find deals for flights from Medford to Knoxville that include hotel bookings?

    Yes. In addition to deals on Medford to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Knoxville.

  • Can I find deals for business class flights from Medford to Knoxville?

    Yes. Cheapflights offers flight deals from Medford to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Medford to Knoxville (average of $296). Flying from Medford to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Medford to Knoxville

Discover the top airline that operate flights from Medford to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$388Average$609FlexibilityNo cancel feeOn-time69%

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