HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$218+ Cheap flights from Key West to Knoxville (EYW - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — TYS
Feb 26 — Mar 51
Wed 2/26
Wed 3/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Key West to Knoxville with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Key West to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 21, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$218
(Mytrip)

Popular in

May

Cheapest in

August

Average price

$313
Provider with most accurate pricing for Key West-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Knoxville McGhee Tyson flights.
Search Deals
From Key West to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals

Find flight deals from Key West to Knoxville

Cheapest flights from Key West to Knoxville
Explore the most affordable flight options available from Key West to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2025.

This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:08 pmEYW - TYS
1 stop5h 22mAllegiant Air
Sun 3/99:54 pmTYS - EYW
1 stop11h 08mAllegiant Air
Deal found 2/20$218
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:20 pmEYW - TYS
1 stop6h 39mAmerican Airlines
Tue 3/112:43 pmTYS - EYW
1 stop4h 16mAmerican Airlines
Deal found 2/20$259
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:08 pmEYW - TYS
1 stop5h 22mMultiple Airlines
Sun 3/96:00 amTYS - EYW
3 stops34h 18mMultiple Airlines
Deal found 2/20$384
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/71:54 pmEYW - TYS
2 stops10h 00mUnited Airlines
Tue 3/117:00 amTYS - EYW
3 stops26h 15mUnited Airlines
Deal found 2/20$421

Find flights from Key West to Knoxville within your budget

Customize your flight search to find flights from Key West to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2025.

Fly from

Key West

Fly to

Knoxville

Route

Depart

Return

Price

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

Fri 3/7

5:08 pm-10:30 pm

1 stop5h 22m

Knoxville McGhee Tyson

Sun 3/9

9:54 pm-9:02 am

1 stop11h 08m

$218

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

Fri 3/7

5:20 pm-11:59 pm

1 stop6h 39m

Knoxville McGhee Tyson

Tue 3/11

2:43 pm-6:59 pm

1 stop4h 16m

$259

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

Fri 3/7

5:08 pm-10:30 pm

1 stop5h 22m

Knoxville McGhee Tyson

Sun 3/9

6:00 am-4:18 pm

3 stops34h 18m

$384

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

Fri 3/7

1:54 pm-11:54 pm

2 stops10h 00m

Knoxville McGhee Tyson

Tue 3/11

7:00 am-9:15 am

3 stops26h 15m

$421

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

Mon 7/14

1:27 pm-7:00 pm

1 stop5h 33m

$295

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

Mon 7/14

7:40 pm-1:21 pm

2 stops17h 41m

$338

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Compare providers for flights from Key West to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Knoxville in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Key West-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Key West-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Key West to Knoxville

Get recent, data-driven insights about flights from Key West to Knoxville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Key West to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Key West to Knoxville (average of $296). Flying from Key West to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from EYW to TYS?

Find hourly flight availability from Key West to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 21, 2025.

It’s optimal to fly from Key West to Knoxville in the morning. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight in the afternoon.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 21, 2025.
United Airlines
7.4
Good
8,759 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.7

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

United Airlines
7.4
Good
8,759 reviews
United Airlines
7.4
Good
8,759 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.7

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Allegiant Air
7.3
Good
765 reviews
United Airlines
7.4
Good
8,759 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.7

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,759 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.7

Reviews

1 / 20

2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Key West to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Key West to Knoxville round-trip?

    Allegiant Air, at $218, was found to be the cheapest airline from Key West to Knoxville.Alternate airlines to your destination round-trip include American Airlines and United Airlines. You may be able to fly from Key West to Knoxville for 52% less than the average price by searching for these airlines.

  • Can I find deals for flights from Key West to Knoxville that include hotel bookings?

    Yes. In addition to deals on Key West to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Knoxville.

  • Can I find deals for business class flights from Key West to Knoxville?

    Yes. Cheapflights offers flight deals from Key West to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Key West to Knoxville (average of $296). Flying from Key West to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Key West?

Book flights to Key West if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Key West to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to Nashville flights
Fort Lauderdale to Nashville flights
Miami to Nashville flights
Tampa to Nashville flights
Jacksonville to Nashville flights
Fort Myers to Nashville flights
West Palm Beach to Nashville flights
Orlando to Memphis flights
Fort Lauderdale to Knoxville flights
Orlando Sanford Intl to Knoxville flights
Orlando to Chattanooga flights
Tampa to Memphis flights
Tampa to Knoxville flights
Sarasota to Nashville flights
Orlando to Knoxville flights
Fort Myers to Knoxville flights
Miami to Knoxville flights
Jacksonville to Memphis flights
Fort Lauderdale to Chattanooga flights
St Petersburg to Knoxville flights
West Palm Beach to Knoxville flights
Panama City to Nashville flights
Pensacola to Nashville flights
Fort Myers to Chattanooga flights
Fort Lauderdale to Memphis flights
West Palm Beach to Chattanooga flights
Miami to Memphis flights
Pensacola to Knoxville flights
Tallahassee to Nashville flights
Miami to Chattanooga flights
Melbourne to Nashville flights
Daytona Beach to Nashville flights
Melbourne to Memphis flights
Daytona Beach to Memphis flights
Tampa to Chattanooga flights
Sarasota to Memphis flights
Pensacola to Chattanooga flights
Sarasota to Knoxville flights
Valparaiso to Nashville flights
Tampa to Blountville flights
Jacksonville to Knoxville flights
Gainesville to Nashville flights
Fort Myers to Memphis flights
Daytona Beach to Knoxville flights
Orlando to Blountville flights
Gainesville to Memphis flights
Punta Gorda to Nashville flights
Jacksonville to Chattanooga flights
Miami to Blountville flights
Pensacola to Memphis flights

Top airline flying from Key West to Knoxville

Discover the top airline that operate flights from Key West to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$583FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.