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$136+ Cheap flights from Key Largo, FL to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — TYS
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheapflights Tip: The best prices from Key Largo to Knoxville McGhee Tyson are usually found in July or October, booked 36 days in advance, depart on a Wednesday or Tuesday and return on a Tuesday

Cheap flight deals from Key Largo to Knoxville

Keep the following information in mind while searching for Key Largo to Knoxville flight deals. Data was last updated April 17, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$214
(Mytrip)

One-way from

$136
(Mytrip)

Popular in

March

Cheapest in

July

Average price

$305
Provider with most accurate pricing for Miami-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Miami-Knoxville McGhee Tyson flights.
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From Key Largo to Knoxville McGhee Tyson
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One-way flight from Key Largo to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 3% potential increase in price ($11 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Key Largo to Knoxville

Cheapest flights from Key Largo to Knoxville
Explore the most affordable flight options available from Key Largo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/610:29 amMIA - TYS
1 stop11h 34mMultiple Airlines
Sat 6/78:10 amTYS - MIA
1 stop11h 48mMultiple Airlines
Deal found 4/17$214
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/309:16 pmMIA - TYS
Nonstop2h 13mAmerican Airlines
Wed 5/77:10 amTYS - MIA
Nonstop2h 05mAmerican Airlines
Deal found 4/16$224
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/308:10 amMIA - TYS
1 stop5h 38mDelta
Wed 5/72:04 pmTYS - MIA
1 stop4h 21mDelta
Deal found 4/16$244
This Frontier deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/16:00 amMIA - TYS
1 stop10h 29mFrontier
Sun 6/85:25 pmTYS - MIA
1 stop13h 05mFrontier
Deal found 4/16$320
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/14:16 pmMIA - TYS
1 stop6h 19mUnited Airlines
Tue 8/195:45 amTYS - MIA
2 stops8h 43mUnited Airlines
Deal found 4/17$500

Cheapflights Fare Finder

Customize your flight search to find flights from Key Largo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Key Largo to Knoxville that are best for you.

Fly from

Key Largo

Fly to

Knoxville

Route

Depart

Return

Price

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Fri 6/6

10:29 am-10:03 pm

1 stop11h 34m

Knoxville McGhee Tyson

Sat 6/7

8:10 am-7:58 pm

1 stop11h 48m

$214

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Wed 4/30

9:16 pm-11:29 pm

Nonstop2h 13m

Knoxville McGhee Tyson

Wed 5/7

7:10 am-9:15 am

Nonstop2h 05m

$224

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Wed 4/30

8:10 am-1:48 pm

1 stop5h 38m

Knoxville McGhee Tyson

Wed 5/7

2:04 pm-6:25 pm

1 stop4h 21m

$244

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Sun 6/1

6:00 am-4:29 pm

1 stop10h 29m

Knoxville McGhee Tyson

Sun 6/8

5:25 pm-6:30 am

1 stop13h 05m

$320

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Fri 7/4

12:20 pm-6:38 pm

1 stop6h 18m

Knoxville McGhee Tyson

Mon 7/7

5:45 am-11:49 am

1 stop6h 04m

$503

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Tue 5/13

2:29 pm-4:12 pm

2 stops25h 43m

$136

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Sun 4/20

6:30 am-3:46 pm

1 stop9h 16m

$150

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Sat 6/14

10:11 pm-12:24 am

Nonstop2h 13m

$212

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Tue 6/17

11:20 am-11:59 pm

2 stops12h 39m

$215

MiamiKnoxville

MIA - TYS

MIATYS

Miami

Mon 5/12

1:29 pm-10:45 pm

2 stops9h 16m

$283

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 11 results
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Best time to book a flight from Key Largo to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Knoxville

How far ahead should I book a flight from Key Largo to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to Knoxville. Price data was last updated on April 11, 2025.

Booking 36 days in advance of your planned departure date is, on average, the best time to get cheap flights from Key Largo to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Key Largo to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Key Largo to Knoxville (average of $296). Flying from Key Largo to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to TYS?

Find hourly flight availability from Key Largo to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Key Largo to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Key Largo to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Knoxville. Price data was last updated on May 12, 2024.

Travelers seeking maximum savings on their Key Largo to Knoxville flight should consider departing on Sunday mornings when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to Knoxville

Explore weekly flight availability from Key Largo to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 17, 2025.

The most flights from KE9 to TYS are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 17, 2025.
See what other customers who have flown with Delta, United Airlines and American Airlines from Key Largo to Knoxville have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Frontier
6.0
Okay
3,281 reviews
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Key Largo?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Key Largo. On average, McGhee Tyson has 2 inbound flights from Key Largo per day from 3 airlines. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines to fly from Key Largo to Knoxville one-way?

    $191 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $212 and $215, respectively.

  • What are the most reliable airlines from Key Largo to Knoxville?

    Consider Finnair (73%), Envoy Air (68%) or American Airlines (60%) when booking your flight. These represent the most reliable airlines when flying from Key Largo to Knoxville.

  • What are the cheapest flights from Key Largo to Knoxville?

    The cheapest flight price from Key Largo to Knoxville is $149. On average you can expect to pay $269. The most popular route, (Miami - Knoxville McGhee Tyson), can usually be booked for $244.

  • Can I find deals for flights from Key Largo to Knoxville that include hotel bookings?

    Yes. In addition to deals on Key Largo to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Knoxville.

  • Can I find deals for business class flights from Key Largo to Knoxville?

    Yes. Cheapflights offers flight deals from Key Largo to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Key Largo to Knoxville (average of $296). Flying from Key Largo to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Key Largo?

Book flights to Key Largo if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 3 airlines flying from Key Largo to Knoxville

Discover the top 3 airlines that operate flights from Key Largo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$91Average$185FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$183Average$390FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$308FlexibilityNo cancel feeOn-timeN/A

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