Knoxville

$116+ Cheap flights from Irvine, CA to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — TYS
Apr 27 — May 41
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Cheapflights Tip: The best prices from Irvine to Knoxville McGhee Tyson are usually found in September or August, booked 89 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

Cheap flight deals from Irvine to Knoxville

Keep the following information in mind while searching for Irvine to Knoxville flight deals. Data was last updated April 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$357
(Mytrip)

One-way from

$116
(Mytrip)

Popular in

January

Cheapest in

September

Average price

$550
Provider with most accurate pricing for Los Angeles-Knoxville McGhee Tyson flight deals.
Provider most trusted by Cheapflights users for Los Angeles-Knoxville McGhee Tyson flights.
From Irvine to Knoxville McGhee Tyson
One-way flight from Irvine to Knoxville McGhee Tyson
Highest demand for flights based on searches. 18% potential increase in price ($120 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from Irvine to Knoxville

Cheapest flights from Irvine to Knoxville
Explore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/301:04 pmLAX - TYS
2 stops28h 51mMultiple Airlines
Fri 5/910:00 amTYS - LAX
2 stops26h 56mMultiple Airlines
Deal found 4/21$360
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1412:40 pmLAX - TYS
1 stop7h 05mUnited Airlines
Tue 5/205:50 amTYS - LAX
1 stop8h 59mUnited Airlines
Deal found 4/22$432
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:15 amLAX - TYS
1 stop6h 02mDelta
Tue 5/205:45 amTYS - LAX
1 stop8h 05mDelta
Deal found 4/22$437
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/138:25 amLAX - TYS
2 stops12h 33mAmerican Airlines
Wed 5/145:20 amTYS - LAX
2 stops12h 58mAmerican Airlines
Deal found 4/21$479
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/266:15 amLAX - TYS
1 stop7h 14mFrontier
Sun 6/295:25 pmTYS - LAX
1 stop10h 04mFrontier
Deal found 4/21$482

Cheapflights Fare Finder

Customize your flight search to find flights from Irvine to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Irvine to Knoxville that are best for you.

Fly from

Irvine

Fly to

Knoxville

Route

Depart

Return

Price

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Wed 4/30

1:04 pm-8:55 pm

2 stops28h 51m

Knoxville McGhee Tyson

Fri 5/9

10:00 am-9:56 am

2 stops26h 56m

$360

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Wed 5/14

12:40 pm-10:45 pm

1 stop7h 05m

Knoxville McGhee Tyson

Tue 5/20

5:50 am-11:49 am

1 stop8h 59m

$432

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Wed 5/14

6:15 am-3:17 pm

1 stop6h 02m

Knoxville McGhee Tyson

Tue 5/20

5:45 am-10:50 am

1 stop8h 05m

$437

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Tue 5/13

8:25 am-11:58 pm

2 stops12h 33m

Knoxville McGhee Tyson

Wed 5/14

5:20 am-3:18 pm

2 stops12h 58m

$479

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Thu 6/26

6:15 am-4:29 pm

1 stop7h 14m

Knoxville McGhee Tyson

Sun 6/29

5:25 pm-12:29 am

1 stop10h 04m

$482

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Sun 5/18

6:52 pm-1:44 pm

1 stop15h 52m

$135

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Mon 4/28

6:30 am-5:13 pm

2 stops31h 43m

$171

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Sun 6/1

6:15 am-4:29 pm

1 stop7h 14m

$180

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Wed 5/14

5:35 am-5:36 pm

1 stop9h 01m

$219

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Fri 7/11

1:22 am-1:26 pm

1 stop9h 04m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 12 results
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Best time to book a flight from Irvine to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Knoxville

How far ahead should I book a flight from Irvine to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Knoxville. Price data was last updated on April 18, 2025.

To ensure you get the cheapest price possible for a flight from Irvine to Knoxville, you should look to book at least 78 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Irvine to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Irvine to Knoxville (average of $296). Flying from Irvine to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to TYS?

Find hourly flight availability from Irvine to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Knoxville as you normally would.

What is the cheapest day to fly from Irvine to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Irvine to Knoxville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Irvine to Knoxville flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 22, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta and United Airlines from Irvine to Knoxville to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
8.0
Very good

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Comfort

7.9

Food

7.1

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from Irvine to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Knoxville from Irvine?

    For a flight from Irvine to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city. McGhee Tyson is the only Knoxville airport and it handles 0 inbound flights from Irvine per day. 4 airlines have flights to Knoxville McGhee Tyson from Irvine on a regular basis.

  • What are the cheapest airlines to fly from Irvine to Knoxville one-way?

    One-way options have recently been found by users for as low as $121 on Frontier. Other airlines that offer cheap prices include Allegiant Air from $187 and American Airlines from $219 one-way.

  • Can I find deals for flights from Irvine to Knoxville that include hotel bookings?

    Yes. In addition to deals on Irvine to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Knoxville.

  • Can I find deals for business class flights from Irvine to Knoxville?

    Yes. Cheapflights offers flight deals from Irvine to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Irvine to Knoxville (average of $296). Flying from Irvine to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Irvine?

Book flights to Irvine if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Irvine to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Irvine to Knoxville

Discover the top 4 airlines that operate flights from Irvine to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$128Average$227FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$228Average$467FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$255Average$435FlexibilityNo cancel feeOn-time71%
DeltaCheapest$276Average$385FlexibilityNo cancel feeOn-timeN/A

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