$116+ Cheap flights from Irvine, CA to Knoxville (TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Irvine to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Irvine to Knoxville McGhee Tyson are usually found in September or August, booked 89 days in advance, depart on a Saturday or Tuesday and return on a Wednesday
Cheap flight deals from Irvine to Knoxville
Keep the following information in mind while searching for Irvine to Knoxville flight deals. Data was last updated April 22, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $357 (Mytrip) |
One-way from | $116 (Mytrip) |
Popular in | January |
Cheapest in | September |
Average price | $550 |
Find flight deals from Irvine to Knoxville
Cheapest flights from Irvine to KnoxvilleExplore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.
Explore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Frontier deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from Irvine to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Irvine to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Wed 4/30
1:04 pm-8:55 pm
2 stops28h 51m
Knoxville McGhee Tyson
Fri 5/9
10:00 am-9:56 am
2 stops26h 56m
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Wed 5/14
12:40 pm-10:45 pm
1 stop7h 05m
Knoxville McGhee Tyson
Tue 5/20
5:50 am-11:49 am
1 stop8h 59m
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Wed 5/14
6:15 am-3:17 pm
1 stop6h 02m
Knoxville McGhee Tyson
Tue 5/20
5:45 am-10:50 am
1 stop8h 05m
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Tue 5/13
8:25 am-11:58 pm
2 stops12h 33m
Knoxville McGhee Tyson
Wed 5/14
5:20 am-3:18 pm
2 stops12h 58m
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Thu 6/26
6:15 am-4:29 pm
1 stop7h 14m
Knoxville McGhee Tyson
Sun 6/29
5:25 pm-12:29 am
1 stop10h 04m
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Sun 5/18
6:52 pm-1:44 pm
1 stop15h 52m
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Mon 4/28
6:30 am-5:13 pm
2 stops31h 43m
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Sun 6/1
6:15 am-4:29 pm
1 stop7h 14m
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Wed 5/14
5:35 am-5:36 pm
1 stop9h 01m
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Fri 7/11
1:22 am-1:26 pm
1 stop9h 04m
Best time to book a flight from Irvine to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Irvine with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Irvine to Knoxville
How far ahead should I book a flight from Irvine to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from Irvine to Knoxville. Price data was last updated on April 18, 2025.
To ensure you get the cheapest price possible for a flight from Irvine to Knoxville, you should look to book at least 78 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Irvine to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Irvine to Knoxville (average of $296). Flying from Irvine to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IR9 to TYS?
Find hourly flight availability from Irvine to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Knoxville as you normally would.
What is the cheapest day to fly from Irvine to Knoxville?
Use this chart to determine the cheapest time to fly round-trip from Irvine to Knoxville. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their Irvine to Knoxville flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Rainfall in Knoxville by month
Plan your trip to Knoxville by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.
Temperature in Knoxville by month
Plan your trip to Knoxville by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 22, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta and United Airlines from Irvine to Knoxville to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
Food
Boarding
Overall
Crew
Entertainment
Reviews
Cheri,Jan 2025
FAT - SEA
Comfort
Food
Boarding
Overall
Crew
Entertainment
Reviews
Cheri,Jan 2025
FAT - SEA
Comfort
Food
Boarding
Overall
Crew
Entertainment
Reviews
Cheri,Jan 2025
FAT - SEA
Comfort
Food
Boarding
Overall
Crew
Entertainment
Reviews
Cheri,Jan 2025
FAT - SEA
Comfort
Food
Boarding
Overall
Crew
Entertainment
Reviews
Cheri,Jan 2025
FAT - SEA
Comfort
Food
Boarding
Overall
Crew
Entertainment
Reviews
Cheri,Jan 2025
FAT - SEA
Related info for your journey
Find useful and relevant information for your journey from Irvine to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Irvine to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from Irvine to Knoxville
Discover the top 4 airlines that operate flights from Irvine to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$128 | Average$227 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$228 | Average$467 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$255 | Average$435 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$276 | Average$385 | FlexibilityNo cancel fee | On-timeN/A |