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Knoxville

$83+ Cheap flights from Iowa to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TYS
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Iowa to Knoxville

Keep the following information in mind while searching for Iowa to Knoxville flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$224
(American Airlines)

One-way from

$83
(Mytrip)

Popular in

March

Cheapest in

January

Average price

$376
Provider with most accurate pricing for Des Moines-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Knoxville McGhee Tyson flights.
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From Iowa to Knoxville McGhee Tyson
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One-way flight from Iowa to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 13% potential increase in price ($57 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Iowa to Knoxville

Cheapest flights from Iowa to Knoxville
Explore the most affordable flight options available from Iowa to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:30 amCID - TYS
1 stop4h 53mDelta
Mon 6/27:10 pmTYS - CID
1 stop4h 50mDelta
Deal found 4/21$233
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/253:38 pmDSM - TYS
1 stop6h 02mUnited Airlines
Mon 6/305:46 pmTYS - DSM
1 stop6h 14mUnited Airlines
Deal found 4/23$249
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/165:55 amMLI - TYS
1 stop6h 31mDelta
Mon 7/217:25 pmTYS - MLI
1 stop4h 04mDelta
Deal found 4/22$249
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/236:00 amOMA - TYS
1 stop6h 24mAmerican Airlines
Wed 7/307:24 amTYS - OMA
1 stop6h 33mAmerican Airlines
Deal found 4/23$249
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/66:30 pmOMA - TYS
1 stop4h 18mDelta
Tue 5/205:45 amTYS - OMA
1 stop5h 38mDelta
Deal found 4/21$254
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/85:25 pmMLI - TYS
1 stop4h 20mUnited Airlines
Mon 5/127:00 amTYS - MLI
1 stop4h 11mUnited Airlines
Deal found 4/23$259
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/168:05 amCID - TYS
1 stop4h 16mUnited Airlines
Mon 7/215:46 pmTYS - CID
1 stop4h 40mUnited Airlines
Deal found 4/22$271
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/83:28 pmOMA - TYS
1 stop6h 17mUnited Airlines
Mon 5/124:14 pmTYS - OMA
1 stop8h 01mUnited Airlines
Deal found 4/23$273
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/35:00 amDSM - TYS
1 stop6h 36mAmerican Airlines
Mon 7/77:46 pmTYS - DSM
1 stop4h 15mAmerican Airlines
Deal found 4/23$274
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/186:14 pmCID - TYS
1 stop22h 58mAllegiant Air
Fri 5/239:30 pmTYS - CID
1 stop11h 51mAllegiant Air
Deal found 4/22$278
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/310:10 amSUX - TYS
1 stop5h 47mUnited Airlines
Tue 6/105:38 pmTYS - SUX
1 stop6h 02mUnited Airlines
Deal found 4/22$296
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1612:58 pmOMA - TYS
1 stop24h 44mAllegiant Air
Fri 8/89:50 amTYS - OMA
1 stop10h 11mAllegiant Air
Deal found 4/23$306

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Iowa to Knoxville that are best for you.

Fly from

Iowa

Fly to

Knoxville

Route

Depart

Return

Price

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Wed 5/28

5:30 am-11:23 am

1 stop4h 53m

Knoxville McGhee Tyson

Mon 6/2

7:10 pm-11:00 pm

1 stop4h 50m

$233

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 6/25

3:38 pm-10:40 pm

1 stop6h 02m

Knoxville McGhee Tyson

Mon 6/30

5:46 pm-11:00 pm

1 stop6h 14m

$249

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Wed 7/23

6:00 am-1:24 pm

1 stop6h 24m

Knoxville McGhee Tyson

Wed 7/30

7:24 am-12:57 pm

1 stop6h 33m

$249

MolineKnoxville

MLI - TYS

MLITYS

Moline Quad-City

Wed 7/16

5:55 am-1:26 pm

1 stop6h 31m

Knoxville McGhee Tyson

Mon 7/21

7:25 pm-10:29 pm

1 stop4h 04m

$249

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Tue 5/6

6:30 pm-11:48 pm

1 stop4h 18m

Knoxville McGhee Tyson

Tue 5/20

5:45 am-10:23 am

1 stop5h 38m

$254

MolineKnoxville

MLI - TYS

MLITYS

Moline Quad-City

Thu 5/8

5:25 pm-10:45 pm

1 stop4h 20m

Knoxville McGhee Tyson

Mon 5/12

7:00 am-10:11 am

1 stop4h 11m

$259

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Wed 7/16

8:05 am-1:21 pm

1 stop4h 16m

Knoxville McGhee Tyson

Mon 7/21

5:46 pm-9:26 pm

1 stop4h 40m

$271

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Thu 5/8

3:28 pm-10:45 pm

1 stop6h 17m

Knoxville McGhee Tyson

Mon 5/12

4:14 pm-11:15 pm

1 stop8h 01m

$273

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Thu 7/3

5:00 am-12:36 pm

1 stop6h 36m

Knoxville McGhee Tyson

Mon 7/7

7:46 pm-11:01 pm

1 stop4h 15m

$274

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Sun 5/18

6:14 pm-6:12 pm

1 stop22h 58m

Knoxville McGhee Tyson

Fri 5/23

9:30 pm-8:21 am

1 stop11h 51m

$278

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 34 results
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Best time to book a flight from Iowa to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Knoxville

What is the cheapest month to book a flight from Iowa to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Iowa to Knoxville (average of $296). Flying from Iowa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to TYS?

Find hourly flight availability from Iowa to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

When flying from Iowa to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 24, 2025.
Read reviews from past customers who have flown Alaska Airlines, Delta and United Airlines from Iowa to Knoxville. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,918 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,920 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,685 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Allegiant Air
7.3
Good
734 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.1

Overall

8.0

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Iowa to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Iowa?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Iowa. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines to fly from Iowa to Knoxville one-way?

    The cheapest airlines for a one-way flight from Iowa to Knoxville are Allegiant Air ($83), American Airlines ($105), and United Airlines ($126).

  • What are the most popular routes from Iowa to Knoxville?

    The most popular flight routes from Iowa to Knoxville are Omaha Eppley Airfield - Knoxville McGhee Tyson, Cedar Rapids - Knoxville McGhee Tyson and Des Moines - Knoxville McGhee Tyson.

  • Can I find deals for flights from Iowa to Knoxville that include hotel bookings?

    Yes. In addition to deals on Iowa to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Knoxville.

  • Can I find deals for business class flights from Iowa to Knoxville?

    Yes. Cheapflights offers flight deals from Iowa to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Knoxville (average of $296). Flying from Iowa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Iowa?

Book flights to Iowa if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Iowa to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Knoxville

Discover the top 3 airlines that operate flights from Iowa to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$321FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$358FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$465FlexibilityNo cancel feeOn-time69%

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