HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$100+ Cheap flights from Iowa to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TYS
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Iowa to Knoxville with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Iowa to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Iowa (USIA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$199
(United Airlines)

One-way from

$100
(American Airlines)
From Iowa to Knoxville McGhee Tyson
Search Deals
One-way flight from Iowa to Knoxville McGhee Tyson
Search Deals

Find flight deals from Iowa to Knoxville

Cheapest flights from Iowa to Knoxville
Explore the most affordable flight options available from Iowa to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/43:59 pmMLI - TYS
1 stop5h 42mUnited Airlines
Sat 2/85:47 pmTYS - MLI
1 stop4h 22mUnited Airlines
Deal found 1/20$199
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/45:32 pmCID - TYS
1 stop4h 09mUnited Airlines
Sat 2/87:00 amTYS - CID
1 stop4h 46mUnited Airlines
Deal found 1/20$199
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/47:50 amOMA - TYS
1 stop4h 28mUnited Airlines
Sat 2/87:00 amTYS - OMA
1 stop4h 35mUnited Airlines
Deal found 1/20$199
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/812:05 pmOMA - TYS
1 stop5h 16mAmerican Airlines
Sat 2/1511:04 amTYS - OMA
2 stops6h 42mAmerican Airlines
Deal found 1/20$203
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/412:55 pmMLI - TYS
2 stops10h 03mAmerican Airlines
Sat 2/86:51 pmTYS - MLI
1 stop4h 07mAmerican Airlines
Deal found 1/20$204
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/411:48 amCID - TYS
2 stops8h 39mAmerican Airlines
Sat 2/86:00 amTYS - CID
1 stop6h 40mAmerican Airlines
Deal found 1/20$204
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/147:25 amDSM - TYS
1 stop8h 21mAmerican Airlines
Sat 2/1512:09 pmTYS - DSM
1 stop8h 12mAmerican Airlines
Deal found 1/20$224
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/412:15 pmCID - TYS
2 stops10h 32mDelta
Sat 2/85:45 amTYS - CID
2 stops9h 15mDelta
Deal found 1/20$227
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/56:55 amOMA - TYS
1 stop8h 14mDelta
Mon 3/106:45 amTYS - OMA
1 stop9h 11mDelta
Deal found 1/20$233
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/46:30 amDSM - TYS
1 stop4h 44mDelta
Sat 2/85:45 amTYS - DSM
1 stop5h 55mDelta
Deal found 1/20$259
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/315:05 pmMLI - TYS
1 stop5h 42mDelta
Fri 2/77:17 pmTYS - MLI
1 stop4h 21mDelta
Deal found 1/20$289
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/58:00 amDSM - TYS
2 stops10h 36mUnited Airlines
Sun 2/95:45 amTYS - DSM
2 stops9h 59mUnited Airlines
Deal found 1/21$425

Find flights from Iowa to Knoxville within your budget

Customize your flight search to find flights from Iowa to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

MolineKnoxville

MLI - TYS

MLITYS

Moline Quad-City

Tue 2/4

3:59 pm-10:41 pm

1 stop5h 42m

Knoxville McGhee Tyson

Sat 2/8

5:47 pm-9:09 pm

1 stop4h 22m

$199

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Tue 2/4

5:32 pm-10:41 pm

1 stop4h 09m

Knoxville McGhee Tyson

Sat 2/8

7:00 am-10:46 am

1 stop4h 46m

$199

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Tue 2/4

7:50 am-1:18 pm

1 stop4h 28m

Knoxville McGhee Tyson

Sat 2/8

7:00 am-10:35 am

1 stop4h 35m

$199

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Sat 2/8

12:05 pm-6:21 pm

1 stop5h 16m

Knoxville McGhee Tyson

Sat 2/15

11:04 am-4:46 pm

2 stops6h 42m

$203

MolineKnoxville

MLI - TYS

MLITYS

Moline Quad-City

Tue 2/4

12:55 pm-11:58 pm

2 stops10h 03m

Knoxville McGhee Tyson

Sat 2/8

6:51 pm-9:58 pm

1 stop4h 07m

$204

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Tue 2/4

11:48 am-9:27 pm

2 stops8h 39m

Knoxville McGhee Tyson

Sat 2/8

6:00 am-11:40 am

1 stop6h 40m

$204

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Fri 2/14

7:25 am-4:46 pm

1 stop8h 21m

Knoxville McGhee Tyson

Sat 2/15

12:09 pm-7:21 pm

1 stop8h 12m

$224

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Tue 2/4

12:15 pm-11:47 pm

2 stops10h 32m

Knoxville McGhee Tyson

Sat 2/8

5:45 am-2:00 pm

2 stops9h 15m

$227

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Wed 3/5

6:55 am-4:09 pm

1 stop8h 14m

Knoxville McGhee Tyson

Mon 3/10

6:45 am-2:56 pm

1 stop9h 11m

$233

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Tue 2/4

6:30 am-12:14 pm

1 stop4h 44m

Knoxville McGhee Tyson

Sat 2/8

5:45 am-10:40 am

1 stop5h 55m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 15 results
1
2

Best time to book a flight from Iowa to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to Knoxville

Get recent, data-driven insights about flights from Iowa to Knoxville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Iowa to Knoxville (average of $297). Flying from Iowa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to TYS?

Find hourly flight availability from Iowa to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from Iowa to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated January 21, 2025.
Read reviews from past customers who have flown United Airlines, Delta and American Airlines from Iowa to Knoxville. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,521 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.6

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,521 reviews
Delta
8.0
Very good
8,521 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.6

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,984 reviews
Delta
8.0
Very good
8,521 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.6

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,521 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Food

7.3

Crew

8.6

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Iowa to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Iowa?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Iowa. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines to fly from Iowa to Knoxville one-way?

    The cheapest airlines for a one-way flight from Iowa to Knoxville are American Airlines ($100), Delta ($119), and United Airlines ($241).

  • What are the most popular routes from Iowa to Knoxville?

    The most popular flight routes from Iowa to Knoxville are Omaha Eppley Airfield - Knoxville McGhee Tyson, Des Moines - Knoxville McGhee Tyson and Cedar Rapids - Knoxville McGhee Tyson.

  • Can I find deals for flights from Iowa to Knoxville that include hotel bookings?

    Yes. In addition to deals on Iowa to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Knoxville.

  • Can I find deals for business class flights from Iowa to Knoxville?

    Yes. Cheapflights offers flight deals from Iowa to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Knoxville (average of $297). Flying from Iowa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Iowa?

Book flights to Iowa if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
LaGuardia to Nashville flights
John F Kennedy Intl to Nashville flights
Newark to Nashville flights
Los Angeles to Nashville flights
O'Hare Intl to Nashville flights
Boston to Nashville flights
Minneapolis to Nashville flights
Seattle to Nashville flights
Baltimore to Nashville flights
Dulles Intl to Nashville flights
Reagan-National to Nashville flights
San Francisco to Nashville flights
Philadelphia to Nashville flights
Dallas/Fort Worth to Nashville flights
Denver to Nashville flights
Orlando to Nashville flights
Raleigh to Nashville flights
Fort Lauderdale to Nashville flights
Hobby to Nashville flights
Ontario to Nashville flights
O'Hare Intl to Knoxville flights
Miami to Nashville flights
Sky Harbor Intl to Nashville flights
Tampa to Nashville flights
George Bush Intcntl to Nashville flights
San Diego to Nashville flights
Burbank to Nashville flights
Detroit to Nashville flights
Midway to Nashville flights
Salt Lake City to Nashville flights
Austin to Nashville flights
Charlotte to Nashville flights
Richmond to Nashville flights
Santa Ana to Nashville flights
Cleveland to Nashville flights
Sacramento to Nashville flights
Hartford to Nashville flights
Portland to Nashville flights
John F Kennedy Intl to Knoxville flights
Newark to Memphis flights
Dallas/Fort Worth to Knoxville flights
Atlanta to Nashville flights
LaGuardia to Knoxville flights
Los Angeles to Memphis flights
Milwaukee to Nashville flights
LaGuardia to Memphis flights
Pittsburgh to Nashville flights
Atlanta to Memphis flights
O'Hare Intl to Memphis flights
Jacksonville to Nashville flights

Top 3 airlines flying from Iowa to Knoxville

Discover the top 3 airlines that operate flights from Iowa to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$227Average$354FlexibilityNo cancel feeOn-time71%
DeltaCheapest$232Average$326FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$472FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.