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$113+ Cheap flights from Iowa to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TYS
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Iowa to Knoxville

Keep the following information in mind while searching for Iowa to Knoxville flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$204
(American Airlines)

One-way from

$113
(Mytrip)

Popular in

June

Cheapest in

January

Average price

$361
Provider with most accurate pricing for Des Moines-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Knoxville McGhee Tyson flights.
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From Iowa to Knoxville McGhee Tyson
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One-way flight from Iowa to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Iowa to Knoxville

Cheapest flights from Iowa to Knoxville
Explore the most affordable flight options available from Iowa to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:35 amCID - TYS
1 stop4h 49mAmerican Airlines
Sat 4/55:15 amTYS - CID
1 stop6h 41mAmerican Airlines
Deal found 2/19$199
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2011:55 amOMA - TYS
1 stop8h 20mDelta
Wed 3/266:45 amTYS - OMA
1 stop6h 50mDelta
Deal found 2/20$233
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/148:00 amDSM - TYS
1 stop11h 39mAllegiant Air
Fri 4/1811:13 amTYS - DSM
1 stop12h 08mAllegiant Air
Deal found 2/20$237
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/55:22 pmDSM - TYS
1 stop5h 20mDelta
Wed 4/95:45 amTYS - DSM
1 stop5h 52mDelta
Deal found 2/19$249
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/43:24 pmMLI - TYS
1 stop7h 31mAmerican Airlines
Mon 4/75:15 amTYS - MLI
1 stop6h 36mAmerican Airlines
Deal found 2/19$249
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/512:49 pmDSM - TYS
2 stops7h 34mAmerican Airlines
Wed 4/912:14 pmTYS - DSM
1 stop5h 29mAmerican Airlines
Deal found 2/19$254
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/305:45 amCID - TYS
1 stop4h 22mDelta
Mon 8/44:00 pmTYS - CID
1 stop6h 50mDelta
Deal found 2/19$254
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/610:24 amCID - TYS
1 stop27h 09mAllegiant Air
Mon 3/106:15 pmTYS - CID
1 stop23h 23mAllegiant Air
Deal found 2/18$257
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/141:31 pmDSM - TYS
2 stops28h 01mMultiple Airlines
Fri 4/1811:13 amTYS - DSM
1 stop12h 08mMultiple Airlines
Deal found 2/20$265
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/147:22 pmOMA - TYS
1 stop16h 17mAllegiant Air
Fri 4/1811:13 amTYS - OMA
1 stop8h 28mAllegiant Air
Deal found 2/20$266
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/58:14 amCID - TYS
1 stop4h 08mUnited Airlines
Wed 4/97:00 amTYS - CID
1 stop4h 36mUnited Airlines
Deal found 2/20$270
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/24:06 pmOMA - TYS
1 stop6h 31mAmerican Airlines
Thu 7/317:56 amTYS - OMA
1 stop6h 04mAmerican Airlines
Deal found 2/19$274

Find flights from Iowa to Knoxville within your budget

Customize your flight search to find flights from Iowa to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Iowa

Fly to

Knoxville

Route

Depart

Return

Price

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Tue 4/1

6:35 am-12:24 pm

1 stop4h 49m

Knoxville McGhee Tyson

Sat 4/5

5:15 am-10:56 am

1 stop6h 41m

$199

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Thu 3/20

11:55 am-9:15 pm

1 stop8h 20m

Knoxville McGhee Tyson

Wed 3/26

6:45 am-12:35 pm

1 stop6h 50m

$233

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Mon 4/14

8:00 am-8:39 pm

1 stop11h 39m

Knoxville McGhee Tyson

Fri 4/18

11:13 am-10:21 pm

1 stop12h 08m

$237

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sat 4/5

5:22 pm-11:42 pm

1 stop5h 20m

Knoxville McGhee Tyson

Wed 4/9

5:45 am-10:37 am

1 stop5h 52m

$249

MolineKnoxville

MLI - TYS

MLITYS

Moline Quad-City

Fri 4/4

3:24 pm-11:55 pm

1 stop7h 31m

Knoxville McGhee Tyson

Mon 4/7

5:15 am-10:51 am

1 stop6h 36m

$249

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sat 4/5

12:49 pm-9:23 pm

2 stops7h 34m

Knoxville McGhee Tyson

Wed 4/9

12:14 pm-4:43 pm

1 stop5h 29m

$254

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Thu 3/6

10:24 am-2:33 pm

1 stop27h 09m

Knoxville McGhee Tyson

Mon 3/10

6:15 pm-4:38 pm

1 stop23h 23m

$257

Cedar RapidsKnoxville

CID - TYS

CIDTYS

Cedar Rapids

Fri 3/7

4:19 pm-11:04 pm

1 stop5h 45m

Knoxville McGhee Tyson

Tue 3/11

5:45 am-3:37 pm

2 stops10h 52m

$264

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Mon 4/14

1:31 pm-6:32 pm

2 stops28h 01m

Knoxville McGhee Tyson

Fri 4/18

11:13 am-10:21 pm

1 stop12h 08m

$265

OmahaKnoxville

OMA - TYS

OMATYS

Omaha Eppley Airfield

Mon 4/14

7:22 pm-12:39 pm

1 stop16h 17m

Knoxville McGhee Tyson

Fri 4/18

11:13 am-6:41 pm

1 stop8h 28m

$266

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 22 results
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Best time to book a flight from Iowa to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to Knoxville

Get recent, data-driven insights about flights from Iowa to Knoxville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Iowa to Knoxville (average of $296). Flying from Iowa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to TYS?

Find hourly flight availability from Iowa to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Iowa to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 20, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from Iowa to Knoxville. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,220 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,766 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.3
Good
765 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,220 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Comfort

8.0

Boarding

8.2

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Iowa to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Iowa?

    Most people fly into Knoxville McGhee Tyson (TYS) if they book a flight to Knoxville from Iowa. McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the most popular routes from Iowa to Knoxville?

    The most popular flight routes from Iowa to Knoxville are Omaha Eppley Airfield - Knoxville McGhee Tyson, Cedar Rapids - Knoxville McGhee Tyson and Des Moines - Knoxville McGhee Tyson.

  • Can I find deals for flights from Iowa to Knoxville that include hotel bookings?

    Yes. In addition to deals on Iowa to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Knoxville.

  • Can I find deals for business class flights from Iowa to Knoxville?

    Yes. Cheapflights offers flight deals from Iowa to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Knoxville (average of $296). Flying from Iowa to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Iowa?

Book flights to Iowa if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Iowa to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Knoxville

Discover the top 3 airlines that operate flights from Iowa to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$227Average$357FlexibilityNo cancel feeOn-time71%
DeltaCheapest$232Average$324FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$471FlexibilityNo cancel feeOn-time69%
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