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Knoxville

$90+ Cheap flights from Indiana to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
IND — TYS
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Indiana to Knoxville

Keep the following information in mind while searching for Indiana to Knoxville flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$194
(Mytrip)

One-way from

$90
(American Airlines)

Popular in

April

Cheapest in

December

Average price

$347

Good round-trip deal

$90 or less

Good one-way deal

$46 or less
Provider with most accurate pricing for Indianapolis-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Knoxville McGhee Tyson flights.
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From Indiana to Knoxville McGhee Tyson
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One-way flight from Indiana to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 10% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Indiana to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Indiana to Knoxville McGhee Tyson.
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Find flight deals from Indiana to Knoxville

Cheapest flights from Indiana to Knoxville
Explore the most affordable flight options available from Indiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/157:50 pmSBN - TYS
Nonstop1h 20mAllegiant Air
Mon 8/185:37 pmTYS - SBN
Nonstop1h 23mAllegiant Air
Deal found 2/20$101
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:30 amCVG - TYS
1 stop11h 24mAllegiant Air
Mon 3/103:18 pmTYS - CVG
1 stop20h 56mAllegiant Air
Deal found 2/19$194
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/312:01 pmIND - TYS
1 stop5h 56mAmerican Airlines
Sat 5/106:09 pmTYS - IND
1 stop4h 06mAmerican Airlines
Deal found 2/20$199
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:45 amORD - TYS
1 stop4h 23mDelta
Sat 3/225:45 amTYS - ORD
1 stop3h 52mDelta
Deal found 2/20$199
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/88:10 pmORD - TYS
Nonstop1h 45mUnited Airlines
Mon 3/105:25 pmTYS - ORD
Nonstop2h 02mUnited Airlines
Deal found 2/20$200
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/11:04 pmSBN - TYS
1 stop5h 34mDelta
Tue 4/85:45 amTYS - SBN
1 stop6h 39mDelta
Deal found 2/19$209
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/112:57 pmMDW - TYS
1 stop5h 33mDelta
Tue 4/157:48 amTYS - MDW
1 stop5h 47mDelta
Deal found 2/19$209
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:45 amORD - TYS
1 stop7h 38mFrontier
Sun 3/94:43 pmTYS - ORD
1 stop8h 40mFrontier
Deal found 2/19$210
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:40 amMDW - TYS
1 stop7h 43mFrontier
Sun 3/94:43 pmTYS - MDW
1 stop8h 36mFrontier
Deal found 2/19$210
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/175:35 amCVG - TYS
1 stop5h 03mAmerican Airlines
Sun 4/206:59 amTYS - CVG
1 stop5h 57mAmerican Airlines
Deal found 2/19$219
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/244:45 pmORD - TYS
1 stop6h 00mAmerican Airlines
Tue 4/295:15 amTYS - ORD
Nonstop2h 07mAmerican Airlines
Deal found 2/20$224
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/274:40 pmORD - TYS
1 stop18h 35mMultiple Airlines
Mon 3/311:05 pmTYS - ORD
2 stops20h 39mMultiple Airlines
Deal found 2/19$226

Find flights from Indiana to Knoxville within your budget

Customize your flight search to find flights from Indiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Indiana

Fly to

Knoxville

Route

Depart

Return

Price

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Thu 3/6

6:30 am-5:54 pm

1 stop11h 24m

Knoxville McGhee Tyson

Mon 3/10

3:18 pm-12:14 pm

1 stop20h 56m

$194

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Sat 5/3

12:01 pm-5:57 pm

1 stop5h 56m

Knoxville McGhee Tyson

Sat 5/10

6:09 pm-10:15 pm

1 stop4h 06m

$199

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 3/18

6:45 am-12:08 pm

1 stop4h 23m

Knoxville McGhee Tyson

Sat 3/22

5:45 am-8:37 am

1 stop3h 52m

$199

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 3/8

8:10 pm-10:55 pm

Nonstop1h 45m

Knoxville McGhee Tyson

Mon 3/10

5:25 pm-6:27 pm

Nonstop2h 02m

$200

South BendKnoxville

SBN - TYS

SBNTYS

South Bend/Michiana

Tue 4/1

1:04 pm-6:38 pm

1 stop5h 34m

Knoxville McGhee Tyson

Tue 4/8

5:45 am-12:24 pm

1 stop6h 39m

$209

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 4/11

2:57 pm-9:30 pm

1 stop5h 33m

Knoxville McGhee Tyson

Tue 4/15

7:48 am-12:35 pm

1 stop5h 47m

$209

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 3/6

6:45 am-3:23 pm

1 stop7h 38m

Knoxville McGhee Tyson

Sun 3/9

4:43 pm-12:23 am

1 stop8h 40m

$210

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Thu 3/6

6:40 am-3:23 pm

1 stop7h 43m

Knoxville McGhee Tyson

Sun 3/9

4:43 pm-12:19 am

1 stop8h 36m

$210

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Thu 4/17

5:35 am-10:38 am

1 stop5h 03m

Knoxville McGhee Tyson

Sun 4/20

6:59 am-12:56 pm

1 stop5h 57m

$219

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 4/24

4:45 pm-11:45 pm

1 stop6h 00m

Knoxville McGhee Tyson

Sat 4/26

5:15 am-6:22 am

Nonstop2h 07m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 38 results
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Best time to book a flight from Indiana to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Indiana to Knoxville

Get recent, data-driven insights about flights from Indiana to Knoxville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Indiana to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Indiana to Knoxville (average of $296). Flying from Indiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to TYS?

Find hourly flight availability from Indiana to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indiana to Knoxville as you normally would.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 20, 2025.
See what other customers who have flown with Delta, United Airlines and Allegiant Air from Indiana to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.3
Good
765 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Frontier
6.0
Okay
3,355 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Indiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Indiana?

    If you book a flight to Knoxville from Indiana, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • What are the cheapest airlines to fly from Indiana to Knoxville one-way?

    The cheapest airlines for a one-way flight from Indiana to Knoxville are American Airlines ($90), Allegiant Air ($92), and Delta ($100).

  • What are the most popular routes from Indiana to Knoxville?

    Most travelers choose Chicago O'Hare Intl - Knoxville McGhee Tyson, Chicago Midway - Knoxville McGhee Tyson or South Bend/Michiana - Knoxville McGhee Tyson when deciding on the best route from Indiana to Knoxville.

  • Can I find deals for flights from Indiana to Knoxville that include hotel bookings?

    Yes. In addition to deals on Indiana to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Knoxville.

  • Can I find deals for business class flights from Indiana to Knoxville?

    Yes. Cheapflights offers flight deals from Indiana to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Indiana to Knoxville (average of $296). Flying from Indiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indiana?

Book flights to Indiana if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Indiana to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Indiana to Knoxville

Discover the top 4 airlines that operate flights from Indiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$75Average$83FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$184Average$373FlexibilityNo cancel feeOn-time71%
DeltaCheapest$197Average$326FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$208Average$345FlexibilityNo cancel feeOn-time69%
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