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Knoxville

$78+ Cheap flights from Indiana to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
IND — TYS
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Indiana to Knoxville

Keep the following information in mind while searching for Indiana to Knoxville flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$78
(Gotogate)

Popular in

March

Cheapest in

December

Average price

$368

Good round-trip deal

$81 or less
Provider with most accurate pricing for Indianapolis-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Knoxville McGhee Tyson flights.
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From Indiana to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 19% potential increase in price ($79 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Indiana to Knoxville McGhee Tyson.
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Find flight deals from Indiana to Knoxville

Cheapest flights from Indiana to Knoxville
Explore the most affordable flight options available from Indiana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Gotogate deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/267:50 pmSBN - TYS
Nonstop1h 20mAllegiant Air
Fri 5/301:31 pmTYS - SBN
Nonstop1h 23mAllegiant Air
Deal found 4/15$78
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3111:54 amORD - TYS
Nonstop1h 40mAmerican Airlines
Sat 6/71:06 pmTYS - ORD
Nonstop1h 53mAmerican Airlines
Deal found 4/16$186
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/207:52 pmORD - TYS
Nonstop1h 50mUnited Airlines
Sat 9/277:00 amTYS - ORD
Nonstop1h 55mUnited Airlines
Deal found 4/17$189
This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/232:54 pmMDW - TYS
Nonstop1h 28mAllegiant Air
Sun 5/258:00 amTYS - MDW
1 stop25h 22mAllegiant Air
Deal found 4/15$193
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/97:30 amIND - TYS
1 stop6h 57mMultiple Airlines
Sun 5/116:00 amTYS - IND
1 stop10h 36mMultiple Airlines
Deal found 4/16$199
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/297:05 amORD - TYS
1 stop5h 14mDelta
Mon 6/27:10 pmTYS - ORD
1 stop5h 48mDelta
Deal found 4/16$204
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:00 amMDW - TYS
1 stop4h 23mDelta
Sun 5/255:45 amTYS - MDW
1 stop4h 55mDelta
Deal found 4/16$204
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/105:25 pmSBN - TYS
1 stop6h 34mDelta
Sat 6/147:46 amTYS - SBN
1 stop5h 50mDelta
Deal found 4/15$209
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/36:05 amIND - TYS
1 stop3h 58mDelta
Fri 8/155:30 amTYS - IND
1 stop3h 27mDelta
Deal found 4/16$219
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1411:53 amCVG - TYS
1 stop5h 43mDelta
Wed 5/215:45 amTYS - CVG
1 stop3h 04mDelta
Deal found 4/16$219
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/207:45 amIND - TYS
1 stop14h 42mAllegiant Air
Mon 6/2312:55 pmTYS - IND
1 stop24h 15mAllegiant Air
Deal found 4/16$221
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/12:03 pmIND - TYS
1 stop6h 05mAmerican Airlines
Mon 5/57:54 pmTYS - IND
1 stop4h 09mAmerican Airlines
Deal found 4/16$229

Cheapflights Fare Finder

Customize your flight search to find flights from Indiana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Indiana to Knoxville that are best for you.

Fly from

Indiana

Fly to

Knoxville

Route

Depart

Return

Price

South BendKnoxville

SBN - TYS

SBNTYS

South Bend/Michiana

Mon 5/26

7:50 pm-9:10 pm

Nonstop1h 20m

Knoxville McGhee Tyson

Fri 5/30

1:31 pm-2:54 pm

Nonstop1h 23m

$78

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 5/31

11:54 am-2:34 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Sat 6/7

1:06 pm-1:59 pm

Nonstop1h 53m

$186

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 5/7

7:30 am-10:15 am

Nonstop1h 45m

Knoxville McGhee Tyson

Wed 5/21

7:00 am-7:57 am

Nonstop1h 57m

$189

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Fri 5/23

2:54 pm-5:22 pm

Nonstop1h 28m

Knoxville McGhee Tyson

Sun 5/25

8:00 am-8:22 am

1 stop25h 22m

$193

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Fri 5/9

7:30 am-2:27 pm

1 stop6h 57m

Knoxville McGhee Tyson

Sun 5/11

6:00 am-4:36 pm

1 stop10h 36m

$199

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 5/29

7:05 am-1:19 pm

1 stop5h 14m

Knoxville McGhee Tyson

Mon 6/2

7:10 pm-11:58 pm

1 stop5h 48m

$204

ChicagoKnoxville

MDW - TYS

MDWTYS

Chicago Midway

Wed 5/21

6:00 am-11:23 am

1 stop4h 23m

Knoxville McGhee Tyson

Sun 5/25

5:45 am-9:40 am

1 stop4h 55m

$204

South BendKnoxville

SBN - TYS

SBNTYS

South Bend/Michiana

Tue 6/10

5:25 pm-11:59 pm

1 stop6h 34m

Knoxville McGhee Tyson

Sat 6/14

7:46 am-1:36 pm

1 stop5h 50m

$209

IndianapolisKnoxville

IND - TYS

INDTYS

Indianapolis

Wed 5/14

6:00 am-10:23 am

1 stop4h 23m

Knoxville McGhee Tyson

Wed 5/21

5:45 am-10:12 am

1 stop4h 27m

$219

CincinnatiKnoxville

CVG - TYS

CVGTYS

Cincinnati Cinci./N. Kentucky

Wed 5/14

11:53 am-5:36 pm

1 stop5h 43m

Knoxville McGhee Tyson

Wed 5/21

5:45 am-8:49 am

1 stop3h 04m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 40 results
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Best time to book a flight from Indiana to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Knoxville

What is the cheapest month to book a flight from Indiana to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Indiana to Knoxville (average of $296). Flying from Indiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to TYS?

Find hourly flight availability from Indiana to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indiana to Knoxville as you normally would.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 17, 2025.
See what other customers who have flown with Delta, United Airlines and Allegiant Air from Indiana to Knoxville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,281 reviews
Delta
8.0
Very good
7,917 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Overall

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Indiana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Indiana?

    If you book a flight to Knoxville from Indiana, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville.

  • What are the cheapest airlines to fly from Indiana to Knoxville one-way?

    The cheapest airlines for a one-way flight from Indiana to Knoxville are Allegiant Air ($94), Delta ($100), and Frontier ($110).

  • What are the most popular routes from Indiana to Knoxville?

    Most travelers choose Chicago O'Hare Intl - Knoxville McGhee Tyson, Chicago Midway - Knoxville McGhee Tyson or South Bend/Michiana - Knoxville McGhee Tyson when deciding on the best route from Indiana to Knoxville.

  • Can I find deals for flights from Indiana to Knoxville that include hotel bookings?

    Yes. In addition to deals on Indiana to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Knoxville.

  • Can I find deals for business class flights from Indiana to Knoxville?

    Yes. Cheapflights offers flight deals from Indiana to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Indiana to Knoxville (average of $296). Flying from Indiana to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indiana?

Book flights to Indiana if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Indiana to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Indiana to Knoxville

Discover the top 4 airlines that operate flights from Indiana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$75Average$84FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$191Average$366FlexibilityNo cancel feeOn-time71%
DeltaCheapest$197Average$313FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$213Average$365FlexibilityNo cancel feeOn-time69%

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