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$75+ Cheap flights from Florida Keys to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — TYS
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from Florida Keys to Knoxville

Keep the following information in mind while searching for Florida Keys to Knoxville flight deals. Data was last updated febrero 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$218
(Mytrip)

One-way from

$75
(Cheapflightsfares)

Popular in

May

Cheapest in

August

Average price

$313
Provider with most accurate pricing for Key West-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Key West-Knoxville McGhee Tyson flights.
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From Florida Keys to Knoxville McGhee Tyson
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One-way flight from Florida Keys to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Florida Keys to Knoxville

Cheapest flights from Florida Keys to Knoxville
Explore the most affordable flight options available from Florida Keys to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/196:00 amMIA - TYS
1 stop5h 14mDelta
mié. 3/265:45 amTYS - MIA
1 stop3h 35mDelta
Deal found 2/18$209
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/75:08 pmEYW - TYS
1 stop5h 22mAllegiant Air
dom. 3/99:54 pmTYS - EYW
1 stop11h 08mAllegiant Air
Deal found 2/20$218
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/198:15 pmMIA - TYS
Nonstop2h 39mAmerican Airlines
mié. 3/266:53 amTYS - MIA
Nonstop2h 11mAmerican Airlines
Deal found 2/18$229
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/192:35 pmMIA - TYS
2 stops21h 28mMultiple Airlines
mié. 3/267:15 amTYS - MIA
1 stop8h 57mMultiple Airlines
Deal found 2/18$232
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/75:20 pmEYW - TYS
1 stop6h 39mAmerican Airlines
mar. 3/112:43 pmTYS - EYW
1 stop4h 16mAmerican Airlines
Deal found 2/20$259
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/75:08 pmEYW - TYS
1 stop5h 22mMultiple Airlines
dom. 3/96:00 amTYS - EYW
3 stops34h 18mMultiple Airlines
Deal found 2/20$384
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/71:54 pmEYW - TYS
2 stops10h 00mUnited Airlines
mar. 3/117:00 amTYS - EYW
3 stops26h 15mUnited Airlines
Deal found 2/20$421
This United deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/1010:14 amMIA - TYS
2 stops12h 53mUnited Airlines
mar. 5/137:00 amTYS - MIA
1 stop7h 56mUnited Airlines
Deal found 2/19$462

Find flights from Florida Keys to Knoxville within your budget

Customize your flight search to find flights from Florida Keys to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Florida Keys

Fly to

Knoxville

Route

Depart

Return

Price

MiamiKnoxville

MIA - TYS

MIATYS

Miami

mié. 3/19

6:00 am-11:14 am

1 stop5h 14m

Knoxville McGhee Tyson

mié. 3/26

5:45 am-9:20 am

1 stop3h 35m

$209

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

vie. 3/7

5:08 pm-10:30 pm

1 stop5h 22m

Knoxville McGhee Tyson

dom. 3/9

9:54 pm-9:02 am

1 stop11h 08m

$218

MiamiKnoxville

MIA - TYS

MIATYS

Miami

mié. 3/19

8:15 pm-10:54 pm

Nonstop2h 39m

Knoxville McGhee Tyson

mié. 3/26

6:53 am-9:04 am

Nonstop2h 11m

$229

MiamiKnoxville

MIA - TYS

MIATYS

Miami

mié. 3/19

2:35 pm-12:03 pm

2 stops21h 28m

Knoxville McGhee Tyson

mié. 3/26

7:15 am-4:12 pm

1 stop8h 57m

$232

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

vie. 3/7

5:20 pm-11:59 pm

1 stop6h 39m

Knoxville McGhee Tyson

mar. 3/11

2:43 pm-6:59 pm

1 stop4h 16m

$259

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

vie. 3/7

5:08 pm-10:30 pm

1 stop5h 22m

Knoxville McGhee Tyson

dom. 3/9

6:00 am-4:18 pm

3 stops34h 18m

$384

Key WestKnoxville

EYW - TYS

EYWTYS

Key West

vie. 3/7

1:54 pm-11:54 pm

2 stops10h 00m

Knoxville McGhee Tyson

mar. 3/11

7:00 am-9:15 am

3 stops26h 15m

$421

MiamiKnoxville

MIA - TYS

MIATYS

Miami

sáb. 5/10

10:14 am-11:07 pm

2 stops12h 53m

Knoxville McGhee Tyson

mar. 5/13

7:00 am-2:56 pm

1 stop7h 56m

$462

MiamiKnoxville

MIA - TYS

MIATYS

Miami

jue. 3/13

6:25 am-3:23 pm

1 stop8h 58m

$75

MiamiKnoxville

MIA - TYS

MIATYS

Miami

mié. 5/7

11:34 am-6:46 pm

3 stops31h 12m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 13 results
1
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Best time to book a flight from Florida Keys to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Florida Keys to Knoxville

Get recent, data-driven insights about flights from Florida Keys to Knoxville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Florida Keys to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Florida Keys to Knoxville (average of $296). Flying from Florida Keys to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from EOA to TYS?

Find hourly flight availability from Florida Keys to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida Keys to Knoxville as you normally would.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated febrero 20, 2025.
Read through reviews of airlines operating flights from Florida Keys to Knoxville, such as Delta, United Airlines and Allegiant Air. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Delta
8.0
Very good
8,220 reviews
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

United Airlines
7.4
Good
8,766 reviews
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Allegiant Air
7.3
Good
765 reviews
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Frontier
6.0
Okay
3,355 reviews
Delta
8.0
Very good
8,220 reviews

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Florida Keys?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from Florida Keys.

  • What are the cheapest airlines to fly from Florida Keys to Knoxville one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $75. Users have also found prices from $216 and $219 on United Airlines and American Airlines, respectively.

  • Can I find deals for flights from Florida Keys to Knoxville that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Knoxville.

  • Can I find deals for business class flights from Florida Keys to Knoxville?

    Yes. Cheapflights offers flight deals from Florida Keys to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Florida Keys to Knoxville (average of $296). Flying from Florida Keys to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florida Keys?

Book flights to Florida Keys if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Florida Keys to Knoxville

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Top airline flying from Florida Keys to Knoxville

Discover the top airline that operate flights from Florida Keys to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$583FlexibilityNo cancel feeOn-time71%
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