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$77+ Cheap flights from Durham, NC to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/25. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — TYS
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Durham to Knoxville

Keep the following information in mind while searching for Durham to Knoxville flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$199
(Delta)

One-way from

$77
(Mytrip)

Popular in

May

Cheapest in

July

Average price

$488
Provider with most accurate pricing for Raleigh-Durham-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Knoxville McGhee Tyson flights.
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From Durham to Knoxville McGhee Tyson
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One-way flight from Durham to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 9% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Durham to Knoxville

Cheapest flights from Durham to Knoxville
Explore the most affordable flight options available from Durham to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/265:00 amRDU - TYS
1 stop3h 59mAmerican Airlines
Sat 3/294:16 pmTYS - RDU
1 stop3h 10mAmerican Airlines
Deal found 2/20$199
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/51:24 pmRDU - TYS
2 stops22h 34mMultiple Airlines
Sat 4/125:18 pmTYS - RDU
1 stop27h 35mMultiple Airlines
Deal found 2/19$230
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/206:47 pmRDU - TYS
1 stop5h 00mDelta
Sun 2/235:45 amTYS - RDU
1 stop4h 17mDelta
Deal found 2/20$269
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/266:00 amRDU - TYS
1 stop4h 00mUnited Airlines
Wed 3/262:25 pmTYS - RDU
2 stops9h 17mUnited Airlines
Deal found 2/20$378

Find flights from Durham to Knoxville within your budget

Customize your flight search to find flights from Durham to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Durham

Fly to

Knoxville

Route

Depart

Return

Price

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Wed 3/26

5:00 am-8:59 am

1 stop3h 59m

Knoxville McGhee Tyson

Sat 3/29

4:16 pm-7:26 pm

1 stop3h 10m

$199

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Sat 4/5

1:24 pm-11:58 am

2 stops22h 34m

Knoxville McGhee Tyson

Sat 4/12

5:18 pm-8:53 pm

1 stop27h 35m

$230

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Fri 3/28

5:20 am-9:20 am

1 stop4h 00m

Knoxville McGhee Tyson

Sat 3/29

5:45 am-8:48 am

1 stop3h 03m

$269

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Thu 2/27

6:00 am-9:59 am

1 stop3h 59m

Knoxville McGhee Tyson

Sun 3/2

7:00 am-2:13 pm

1 stop7h 13m

$310

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Tue 3/25

10:58 am-11:31 pm

1 stop12h 33m

$77

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Wed 3/26

6:00 am-10:00 am

1 stop4h 00m

$100

RaleighKnoxville

RDU - TYS

RDUTYS

Raleigh-Durham

Sat 3/1

9:04 am-2:16 pm

1 stop5h 12m

$340

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Best time to book a flight from Durham to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Durham to Knoxville

Get recent, data-driven insights about flights from Durham to Knoxville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Durham to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Durham to Knoxville (average of $296). Flying from Durham to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to TYS?

Find hourly flight availability from Durham to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Durham to Knoxville as you normally would.

What is the cheapest day to fly from Durham to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Durham to Knoxville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Durham to Knoxville flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 20, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Durham to Knoxville. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,220 reviews

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,220 reviews
Delta
8.0
Very good
8,220 reviews

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,766 reviews
Delta
8.0
Very good
8,220 reviews

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,220 reviews

Comfort

8.0

Food

7.3

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Durham to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Durham?

    If you book a flight to Knoxville from Durham, you will be flying to McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 0 flights from Durham to McGhee Tyson per day from 3 different airlines.

  • Can I find deals for flights from Durham to Knoxville that include hotel bookings?

    Yes. In addition to deals on Durham to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Knoxville.

  • Can I find deals for business class flights from Durham to Knoxville?

    Yes. Cheapflights offers flight deals from Durham to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Durham to Knoxville (average of $296). Flying from Durham to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Durham?

Book flights to Durham if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Maryville
Oak Ridge
Alcoa
Murphy

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Top 3 airlines flying from Durham to Knoxville

Discover the top 3 airlines that operate flights from Durham to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$217Average$431FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$223Average$328FlexibilityNo cancel feeOn-time69%
DeltaCheapest$228Average$318FlexibilityNo cancel feeOn-timeN/A
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