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$69+ Cheap flights from Colorado to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
Feb 4 — Feb 111
Tue 2/4
Tue 2/11
1 adult, Economy
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Cheap flight deals from Colorado to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Colorado (USCO) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$98
(Cheapflightsfares)

One-way from

$69
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$302

Good round-trip deal

$100 or less

Good one-way deal

$74 or less
Provider with most accurate pricing for Denver Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Knoxville McGhee Tyson flights.
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From Colorado to Knoxville McGhee Tyson
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One-way flight from Colorado to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 12% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in January 2025
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Price to beat on a round-trip flight from Colorado to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Colorado to Knoxville McGhee Tyson.
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Find flight deals from Colorado to Knoxville

Cheapest flights from Colorado to Knoxville
Explore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/108:21 amDEN - TYS
Nonstop2h 44mAllegiant Air
Sun 4/136:20 amTYS - DEN
Nonstop3h 11mAllegiant Air
Deal found 1/30$98
This Frontier deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/3011:00 amDEN - TYS
Nonstop2h 43mFrontier
Thu 4/34:31 pmTYS - DEN
Nonstop3h 25mFrontier
Deal found 1/28$118
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/265:33 pmDEN - TYS
Nonstop2h 57mUnited Airlines
Wed 3/57:00 amTYS - DEN
1 stop5h 35mUnited Airlines
Deal found 1/29$239
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2811:59 pmDEN - TYS
1 stop7h 18mAmerican Airlines
Tue 3/42:43 pmTYS - DEN
1 stop7h 50mAmerican Airlines
Deal found 1/28$249
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/214:50 pmCOS - TYS
1 stop4h 59mAmerican Airlines
Tue 2/256:36 pmTYS - COS
1 stop5h 53mAmerican Airlines
Deal found 1/30$249
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/36:50 pmDEN - TYS
3 stops21h 49mMultiple Airlines
Thu 3/67:15 amTYS - DEN
Nonstop3h 11mMultiple Airlines
Deal found 1/28$255
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/26:00 amDEN - TYS
1 stop5h 40mDelta
Sat 4/57:50 amTYS - DEN
1 stop8h 03mDelta
Deal found 1/28$264
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/218:20 amCOS - TYS
2 stops12h 44mDelta
Tue 2/251:00 pmTYS - COS
2 stops10h 05mDelta
Deal found 1/30$358
This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/125:30 amGJT - TYS
1 stop7h 42mUnited Airlines
Sat 2/152:40 pmTYS - GJT
2 stops9h 38mUnited Airlines
Deal found 1/29$374
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/262:46 pmMTJ - TYS
1 stop7h 12mAmerican Airlines
Sun 3/305:51 amTYS - MTJ
1 stop7h 26mAmerican Airlines
Deal found 1/29$394
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/104:50 pmGJT - TYS
1 stop5h 15mAmerican Airlines
Sat 5/1712:35 pmTYS - GJT
2 stops10h 56mAmerican Airlines
Deal found 1/29$399
This United deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2110:45 amCOS - TYS
2 stops10h 15mUnited Airlines
Tue 2/257:05 amTYS - COS
2 stops11h 29mUnited Airlines
Deal found 1/29$414

Find flights from Colorado to Knoxville within your budget

Customize your flight search to find flights from Colorado to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 4/10

8:21 am-1:05 pm

Nonstop2h 44m

Knoxville McGhee Tyson

Sun 4/13

6:20 am-7:31 am

Nonstop3h 11m

$98

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 3/30

11:00 am-3:43 pm

Nonstop2h 43m

Knoxville McGhee Tyson

Thu 4/3

4:31 pm-5:56 pm

Nonstop3h 25m

$118

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 2/26

5:33 pm-10:30 pm

Nonstop2h 57m

Knoxville McGhee Tyson

Wed 3/5

7:00 am-10:35 am

1 stop5h 35m

$239

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 2/28

11:59 pm-9:17 am

1 stop7h 18m

Knoxville McGhee Tyson

Tue 3/4

2:43 pm-8:33 pm

1 stop7h 50m

$249

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Fri 2/21

4:50 pm-11:49 pm

1 stop4h 59m

Knoxville McGhee Tyson

Tue 2/25

6:36 pm-10:29 pm

1 stop5h 53m

$249

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 3/3

6:50 pm-6:39 pm

3 stops21h 49m

Knoxville McGhee Tyson

Thu 3/6

7:15 am-8:26 am

Nonstop3h 11m

$255

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Wed 4/2

6:00 am-1:40 pm

1 stop5h 40m

Knoxville McGhee Tyson

Sat 4/5

7:50 am-1:53 pm

1 stop8h 03m

$264

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Fri 2/21

8:20 am-11:04 pm

2 stops12h 44m

Knoxville McGhee Tyson

Tue 2/25

1:00 pm-9:05 pm

2 stops10h 05m

$358

Grand JunctionKnoxville

GJT - TYS

GJTTYS

Grand Junction Regnl

Wed 2/12

5:30 am-3:12 pm

1 stop7h 42m

Knoxville McGhee Tyson

Sat 2/15

2:40 pm-10:18 pm

2 stops9h 38m

$374

MontroseKnoxville

MTJ - TYS

MTJTYS

Montrose County

Wed 3/26

2:46 pm-11:58 pm

1 stop7h 12m

Knoxville McGhee Tyson

Sun 3/30

5:51 am-11:17 am

1 stop7h 26m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/29

Showing 1-10 of 29 results
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Best time to book a flight from Colorado to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Colorado to Knoxville

Get recent, data-driven insights about flights from Colorado to Knoxville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Colorado to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $296). Flying from Colorado to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to TYS?

Find hourly flight availability from Colorado to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 30, 2025.

When flying from Colorado to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Colorado to Knoxville

Explore weekly flight availability from Colorado to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 30, 2025.

The most flights from USCO to TYS are scheduled on a Thursday (4 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated January 30, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Delta and United Airlines from Colorado to Knoxville by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,686 reviews

Comfort

7.9

Entertainment

7.1

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Alaska Airlines
8.0
Very good
9,686 reviews
Alaska Airlines
8.0
Very good
9,686 reviews

Comfort

7.9

Entertainment

7.1

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Delta
8.0
Very good
8,450 reviews
Alaska Airlines
8.0
Very good
9,686 reviews

Comfort

7.9

Entertainment

7.1

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

United Airlines
7.4
Good
8,906 reviews
Alaska Airlines
8.0
Very good
9,686 reviews

Comfort

7.9

Entertainment

7.1

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Allegiant Air
7.3
Good
790 reviews
Alaska Airlines
8.0
Very good
9,686 reviews

Comfort

7.9

Entertainment

7.1

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,686 reviews

Comfort

7.9

Entertainment

7.1

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from Colorado to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Colorado?

    For a flight from Colorado to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How popular is this Colorado to Knoxville flight route?

    The Colorado to Knoxville McGhee Tyson flight path was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Colorado to Knoxville one-way?

    One-way options have recently been found by users for as low as $69 on Allegiant Air. Other airlines that offer cheap prices include Frontier from $107 and American Airlines from $178 one-way.

  • What are the most popular routes from Colorado to Knoxville?

    Most travelers choose Denver Intl - Knoxville McGhee Tyson, Colorado Springs - Knoxville McGhee Tyson or Grand Junction Regnl - Knoxville McGhee Tyson when deciding on the best route from Colorado to Knoxville.

  • What are the most reliable airlines from Colorado to Knoxville?

    Before booking your flight to Knoxville from Colorado, check out the most reliable airlines to get you to your destination on time: SkyWest Airlines (83%), Allegiant Air (79%), Frontier( 68%).

  • What are the cheapest flights from Colorado to Knoxville?

    Looking for the cheapest flight from Colorado to Knoxville? While on average our users pay $131, our data indicates the cheapest price to be $59. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $98.

  • Can I find deals for flights from Colorado to Knoxville that include hotel bookings?

    Yes. In addition to deals on Colorado to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Knoxville.

  • Can I find deals for business class flights from Colorado to Knoxville?

    Yes. Cheapflights offers flight deals from Colorado to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $296). Flying from Colorado to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Colorado?

Book flights to Colorado if you plan to visit one of these locations
Morristown
Corbin
Cherokee
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for Colorado to Knoxville

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Top 5 airlines flying from Colorado to Knoxville

Discover the top 5 airlines that operate flights from Colorado to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$68Average$147FlexibilityNo cancel feeOn-time88%
FrontierCheapest$75Average$161FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$155Average$397FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$324FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$224Average$517FlexibilityNo cancel feeOn-time69%
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