HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$59+ Cheap flights from Colorado to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — TYS
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Colorado to Knoxville with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Colorado to Knoxville

Keep the following information in mind while searching for Colorado to Knoxville flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$98
(Booking.com)

One-way from

$59
(Booking.com)

Popular in

March

Cheapest in

August

Average price

$348

Good round-trip deal

$134 or less

Good one-way deal

$109 or less
Provider with most accurate pricing for Denver Intl-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Knoxville McGhee Tyson flights.
Search Deals
From Colorado to Knoxville McGhee Tyson
Search Deals
One-way flight from Colorado to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
Search Deals
Price to beat on a round-trip flight from Colorado to Knoxville McGhee Tyson.
Search Deals
Price to beat on a one-way flight from Colorado to Knoxville McGhee Tyson.
Search Deals

Find flight deals from Colorado to Knoxville

Cheapest flights from Colorado to Knoxville
Explore the most affordable flight options available from Colorado to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Booking.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/248:21 amDEN - TYS
Nonstop2h 44mAllegiant Air
Sun 4/276:20 amTYS - DEN
Nonstop3h 11mAllegiant Air
Deal found 3/30$98
This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1710:56 amDEN - TYS
Nonstop2h 45mFrontier
Sun 4/204:43 pmTYS - DEN
Nonstop3h 25mFrontier
Deal found 3/30$115
This Mytrip deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/187:00 amDEN - TYS
Nonstop2h 46mMultiple Airlines
Sun 4/206:20 amTYS - DEN
Nonstop3h 11mMultiple Airlines
Deal found 3/29$127
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/116:00 amDEN - TYS
1 stop5h 22mUnited Airlines
Thu 5/294:52 pmTYS - DEN
Nonstop3h 16mUnited Airlines
Deal found 3/30$239
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/25:00 amDEN - TYS
1 stop6h 26mAmerican Airlines
Sat 8/96:36 pmTYS - DEN
1 stop6h 56mAmerican Airlines
Deal found 3/31$249
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1412:55 amDEN - TYS
1 stop6h 26mDelta
Wed 4/235:30 amTYS - DEN
1 stop5h 55mDelta
Deal found 3/30$264
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:20 amDRO - TYS
1 stop6h 45mAmerican Airlines
Sun 5/257:00 amTYS - DRO
1 stop7h 11mAmerican Airlines
Deal found 3/31$318
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/25:00 amCOS - TYS
1 stop6h 26mAmerican Airlines
Sat 8/96:36 pmTYS - COS
1 stop6h 48mAmerican Airlines
Deal found 3/29$324
This United deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/210:30 amCOS - TYS
2 stops10h 05mUnited Airlines
Sat 8/97:00 amTYS - COS
1 stop6h 08mUnited Airlines
Deal found 3/30$385
This United deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/301:31 pmGJT - TYS
1 stop6h 59mUnited Airlines
Sat 5/34:14 pmTYS - GJT
1 stop6h 17mUnited Airlines
Deal found 3/31$409
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/245:30 amGJT - TYS
1 stop5h 56mAmerican Airlines
Tue 7/12:48 pmTYS - GJT
2 stops11h 27mAmerican Airlines
Deal found 3/30$420
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/267:00 amDRO - TYS
1 stop5h 44mUnited Airlines
Mon 4/284:20 pmTYS - DRO
1 stop7h 50mUnited Airlines
Deal found 3/31$422

Cheapflights Fare Finder

Customize your flight search to find flights from Colorado to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Colorado to Knoxville that are best for you.

Fly from

Colorado

Fly to

Knoxville

Route

Depart

Return

Price

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 4/24

8:21 am-1:05 pm

Nonstop2h 44m

Knoxville McGhee Tyson

Sun 4/27

6:20 am-7:31 am

Nonstop3h 11m

$98

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Thu 4/17

10:56 am-3:41 pm

Nonstop2h 45m

Knoxville McGhee Tyson

Sun 4/20

4:43 pm-6:08 pm

Nonstop3h 25m

$115

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Fri 4/18

7:00 am-11:46 am

Nonstop2h 46m

Knoxville McGhee Tyson

Sun 4/20

6:20 am-7:31 am

Nonstop3h 11m

$127

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sun 5/11

6:00 am-1:22 pm

1 stop5h 22m

Knoxville McGhee Tyson

Thu 5/29

4:52 pm-6:08 pm

Nonstop3h 16m

$239

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Sat 8/2

5:00 am-1:26 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sat 8/9

6:36 pm-11:32 pm

1 stop6h 56m

$249

DenverKnoxville

DEN - TYS

DENTYS

Denver Intl

Mon 4/14

12:55 am-9:21 am

1 stop6h 26m

Knoxville McGhee Tyson

Thu 4/24

5:30 am-9:25 am

1 stop5h 55m

$264

DurangoKnoxville

DRO - TYS

DROTYS

Durango La Plata County

Tue 5/20

5:20 am-2:05 pm

1 stop6h 45m

Knoxville McGhee Tyson

Sun 5/25

7:00 am-12:11 pm

1 stop7h 11m

$318

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Sat 8/2

5:00 am-1:26 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sat 8/9

6:36 pm-11:24 pm

1 stop6h 48m

$324

Colorado SpringsKnoxville

COS - TYS

COSTYS

Colorado Springs

Sat 8/2

10:30 am-10:35 pm

2 stops10h 05m

Knoxville McGhee Tyson

Sat 8/9

7:00 am-11:08 am

1 stop6h 08m

$385

Grand JunctionKnoxville

GJT - TYS

GJTTYS

Grand Junction Regnl

Wed 4/30

1:31 pm-10:30 pm

1 stop6h 59m

Knoxville McGhee Tyson

Sat 5/3

4:14 pm-8:31 pm

1 stop6h 17m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/29

Showing 1-10 of 24 results
1
2
3

Best time to book a flight from Colorado to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Colorado with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Colorado to Knoxville

What is the cheapest month to book a flight from Colorado to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $296). Flying from Colorado to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CO to TYS?

Find hourly flight availability from Colorado to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

When flying from Colorado to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Colorado to Knoxville

Explore weekly flight availability from Colorado to Knoxville. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 31, 2025.

The most flights from USCO to TYS are scheduled on a Sunday (3 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 31, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and Allegiant Air from Colorado to Knoxville by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,614 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
731 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,275 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Colorado to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Colorado?

    For a flight from Colorado to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How popular is this Colorado to Knoxville flight route?

    The Colorado to Knoxville McGhee Tyson flight path was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Colorado to Knoxville one-way?

    One-way options have recently been found by users for as low as $59 on Allegiant Air. Other airlines that offer cheap prices include American Airlines from $174 and Frontier from $199 one-way.

  • What are the most popular routes from Colorado to Knoxville?

    Most travelers choose Denver Intl - Knoxville McGhee Tyson, Colorado Springs - Knoxville McGhee Tyson or Grand Junction Regnl - Knoxville McGhee Tyson when deciding on the best route from Colorado to Knoxville.

  • What are the most reliable airlines from Colorado to Knoxville?

    Before booking your flight to Knoxville from Colorado, check out the most reliable airlines to get you to your destination on time: Frontier (100%), Allegiant Air (94%), SkyWest Airlines( 85%).

  • What are the cheapest flights from Colorado to Knoxville?

    Looking for the cheapest flight from Colorado to Knoxville? While on average our users pay $211, our data indicates the cheapest price to be $67. The most popular route (Denver Intl - Knoxville McGhee Tyson), is priced around $98.

  • Can I find deals for flights from Colorado to Knoxville that include hotel bookings?

    Yes. In addition to deals on Colorado to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Colorado to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Colorado to Knoxville.

  • Can I find deals for business class flights from Colorado to Knoxville?

    Yes. Cheapflights offers flight deals from Colorado to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Colorado to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Colorado to Knoxville (average of $296). Flying from Colorado to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Colorado?

Book flights to Colorado if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Colorado to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Nashville flights
Newark to Nashville flights
LaGuardia to Nashville flights
Los Angeles to Nashville flights
Boston to Nashville flights
O'Hare Intl to Nashville flights
Dulles Intl to Nashville flights
Dallas/Fort Worth to Nashville flights
Seattle to Nashville flights
Reagan-National to Nashville flights
Denver to Nashville flights
San Francisco to Nashville flights
Minneapolis to Nashville flights
Philadelphia to Nashville flights
Detroit to Nashville flights
Baltimore to Nashville flights
Raleigh to Nashville flights
Ontario to Nashville flights
Portland to Nashville flights
Sky Harbor Intl to Nashville flights
LaGuardia to Knoxville flights
Salt Lake City to Nashville flights
O'Hare Intl to Knoxville flights
Hobby to Nashville flights
Orlando to Nashville flights
Rochester to Nashville flights
San Diego to Nashville flights
Burbank to Nashville flights
Fort Lauderdale to Nashville flights
Hartford to Nashville flights
Dallas/Fort Worth to Knoxville flights
Sacramento to Nashville flights
Newark to Memphis flights
John F Kennedy Intl to Knoxville flights
LaGuardia to Memphis flights
Las Vegas to Nashville flights
Miami to Nashville flights
Santa Ana to Nashville flights
George Bush Intcntl to Nashville flights
Philadelphia to Knoxville flights
Tampa to Nashville flights
Austin to Nashville flights
West Palm Beach to Nashville flights
Charlotte to Nashville flights
Hobby to Knoxville flights
Dulles Intl to Knoxville flights
O'Hare Intl to Memphis flights
Reagan-National to Memphis flights
John F Kennedy Intl to Memphis flights
Cleveland to Nashville flights

Top 5 airlines flying from Colorado to Knoxville

Discover the top 5 airlines that operate flights from Colorado to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$65Average$141FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$68Average$142FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$148Average$379FlexibilityNo cancel feeOn-time71%
DeltaCheapest$215Average$321FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$224Average$557FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.