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$165+ Cheap flights from Central America to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
SJO — TYS
Apr 9 — Apr 161
Wed 4/9
Wed 4/16
1 adult, Economy
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Cheap flight deals from Central America to Knoxville

Keep the following information in mind while searching for Central America to Knoxville flight deals. Data was last updated April 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$452
(American Airlines)

One-way from

$165
(Mytrip)
Provider with most accurate pricing for San Salvador El Salvador Intl-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for San Salvador El Salvador Intl-Knoxville McGhee Tyson flights.
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From Central America to Knoxville McGhee Tyson
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One-way flight from Central America to Knoxville McGhee Tyson
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Find flight deals from Central America to Knoxville

Cheapest flights from Central America to Knoxville
Explore the most affordable flight options available from Central America to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2025.

This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/246:00 amSAL - TYS
1 stop15h 29mAmerican Airlines
Mon 4/287:54 pmTYS - SAL
2 stops18h 34mAmerican Airlines
Deal found 4/4$452
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2012:23 pmSJO - TYS
1 stop20h 10mMultiple Airlines
Fri 10/248:15 amTYS - SJO
1 stop6h 25mMultiple Airlines
Deal found 4/4$457
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/202:25 pmSJO - TYS
1 stop6h 47mAmerican Airlines
Fri 10/248:46 pmTYS - SJO
2 stops18h 14mAmerican Airlines
Deal found 4/4$498
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/117:55 amSJO - TYS
1 stop27h 41mUnited Airlines
Sat 4/197:00 amTYS - SJO
1 stop7h 26mUnited Airlines
Deal found 4/4$629
This Mytrip deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/74:40 pmTGU - TYS
3 stops26h 15mMultiple Airlines
Thu 5/228:35 pmTYS - TGU
2 stops24h 30mMultiple Airlines
Deal found 4/3$864
This Air Canada deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/268:00 amSJO - TYS
2 stops31h 05mAir Canada
Sun 8/35:45 amTYS - SJO
2 stops16h 40mAir Canada
Deal found 4/3$1,785

Cheapflights Fare Finder

Customize your flight search to find flights from Central America to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
Use the filters below to find and compare flights from Central America to Knoxville that are best for you.

Fly from

Central America

Fly to

Knoxville

Route

Depart

Return

Price

San SalvadorKnoxville

SAL - TYS

SALTYS

San Salvador El Salvador Intl

Thu 4/24

6:00 am-11:29 pm

1 stop15h 29m

Knoxville McGhee Tyson

Mon 4/28

7:54 pm-12:28 pm

2 stops18h 34m

$452

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Thu 5/15

6:03 am-10:20 pm

1 stop14h 17m

Knoxville McGhee Tyson

Mon 6/2

7:10 am-6:35 pm

1 stop13h 25m

$509

TegucigalpaKnoxville

TGU - TYS

TGUTYS

Tegucigalpa Toncontin

Wed 5/7

4:40 pm-8:55 pm

3 stops26h 15m

Knoxville McGhee Tyson

Thu 5/22

8:35 pm-7:05 pm

2 stops24h 30m

$864

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Sat 7/26

8:00 am-5:05 pm

2 stops31h 05m

Knoxville McGhee Tyson

Sun 8/3

5:45 am-8:25 pm

2 stops16h 40m

$1,785

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Fri 7/11

7:55 am-10:35 pm

2 stops12h 40m

Knoxville McGhee Tyson

Sat 7/19

9:55 am-10:50 pm

2 stops14h 55m

$2,178

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Thu 5/1

12:55 am-10:18 pm

1 stop19h 23m

$165

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Fri 5/2

12:27 pm-11:29 pm

1 stop9h 02m

$323

TegucigalpaKnoxville

TGU - TYS

TGUTYS

Tegucigalpa Toncontin

Wed 6/4

9:25 am-8:44 pm

2 stops33h 19m

$342

San JoséKnoxville

SJO - TYS

SJOTYS

San José Juan Santamaria Intl

Thu 5/1

1:40 am-10:05 am

2 stops30h 25m

$726

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/4

Best time to book a flight from Central America to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Central America with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Central America to Knoxville

What is the cheapest month to book a flight from Central America to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Central America to Knoxville (average of $296). Flying from Central America to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CA to TYS?

Find hourly flight availability from Central America to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 4, 2025.

When flying from Central America to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 4, 2025.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Food

6.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Food

6.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
Air Canada
7.0
Good
9,040 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Food

6.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
Avianca
6.7
Okay
2,304 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Food

6.5

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Central America to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Central America?

    For a flight from Central America to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • What are the most popular routes from Central America to Knoxville?

    The most popular flight routes from Central America to Knoxville are San José Juan Santamaria Intl - Knoxville McGhee Tyson, San Salvador El Salvador Intl - Knoxville McGhee Tyson and Tegucigalpa Toncontin - Knoxville McGhee Tyson.

  • Can I find deals for flights from Central America to Knoxville that include hotel bookings?

    Yes. In addition to deals on Central America to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Central America to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Central America to Knoxville.

  • Can I find deals for business class flights from Central America to Knoxville?

    Yes. Cheapflights offers flight deals from Central America to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Central America to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Central America to Knoxville (average of $296). Flying from Central America to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Central America?

Book flights to Central America if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 3 airlines flying from Central America to Knoxville

Discover the top 3 airlines that operate flights from Central America to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$313Average$941FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$411Average$701FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$462Average$634FlexibilityNo cancel feeOn-time69%

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