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$135+ Cheap flights from Buffalo to Knoxville (BUF - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — TYS
mars 26 — avr. 21
mer. 3/26
mer. 4/2
1 adult, Economy
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Cheapflights Tip: The best prices from Buffalo to Knoxville McGhee Tyson are usually found in September or February, booked 32 days in advance, depart on a Tuesday or Sunday and return on a Wednesday

Cheap flight deals from Buffalo to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated mars 21, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$199
(American Airlines)

One-way from

$135

Popular in

May

Cheapest in

September

Average price

$318
Provider with most accurate pricing for Buffalo-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Knoxville McGhee Tyson flights.
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From Buffalo to Knoxville McGhee Tyson
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One-way flight from Buffalo to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 17% potential increase in price ($68 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Buffalo to Knoxville

Cheapest flights from Buffalo to Knoxville
Explore the most affordable flight options available from Buffalo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mars 21, 2025.

This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/157:19 pmBUF - TYS
1 stop4h 26mAmerican Airlines
mar. 4/225:30 pmTYS - BUF
1 stop5h 15mAmerican Airlines
Deal found 3/19$199
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 5/296:35 pmBUF - TYS
1 stop5h 16mDelta
jeu. 6/56:20 pmTYS - BUF
1 stop4h 53mDelta
Deal found 3/20$243
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 4/47:45 pmBUF - TYS
1 stop4h 14mUnited Airlines
mar. 4/87:00 amTYS - BUF
2 stops7h 05mUnited Airlines
Deal found 3/20$264
This Mytrip deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 7/2711:40 amBUF - TYS
2 stops34h 35mMultiple Airlines
dim. 8/103:54 pmTYS - BUF
2 stops18h 50mMultiple Airlines
Deal found 3/20$436

Cheapflights Fare Finder

Customize your flight search to find flights from Buffalo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 21, 2025.
Use the filters below to find and compare flights from Buffalo to Knoxville that are best for you.

Fly from

Buffalo

Fly to

Knoxville

Route

Depart

Return

Price

BuffaloKnoxville

BUF - TYS

BUFTYS

Buffalo

mar. 4/15

7:19 pm-11:45 pm

1 stop4h 26m

Knoxville McGhee Tyson

mar. 4/22

5:30 pm-10:45 pm

1 stop5h 15m

$199

BuffaloKnoxville

BUF - TYS

BUFTYS

Buffalo

jeu. 5/29

6:35 pm-11:51 pm

1 stop5h 16m

Knoxville McGhee Tyson

jeu. 6/5

6:20 pm-11:13 pm

1 stop4h 53m

$243

BuffaloKnoxville

BUF - TYS

BUFTYS

Buffalo

ven. 4/4

7:45 pm-11:59 pm

1 stop4h 14m

Knoxville McGhee Tyson

mar. 4/8

7:00 am-2:05 pm

2 stops7h 05m

$264

BuffaloKnoxville

BUF - TYS

BUFTYS

Buffalo

dim. 7/27

11:40 am-10:15 pm

2 stops34h 35m

Knoxville McGhee Tyson

dim. 8/10

3:54 pm-10:44 am

2 stops18h 50m

$436

BuffaloKnoxville

BUF - TYS

BUFTYS

Buffalo

mar. 4/15

5:51 pm-10:22 pm

1 stop4h 31m

$135

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/20

Compare providers for flights from Buffalo to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Knoxville

How far ahead should I book a flight from Buffalo to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to Knoxville. Price data was last updated on March 14, 2025.

Booking 32 days in advance of your planned departure date is, on average, the best time to get cheap flights from Buffalo to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Buffalo to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Knoxville (average of $295). Flying from Buffalo to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to TYS?

Find hourly flight availability from Buffalo to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mars 21, 2025.

It’s typically best to fly out from Buffalo to Knoxville in the evening. Doing so could potentially save you 29% on the flight price compared to flying at noon, which is usually more expensive.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated mars 21, 2025.
Delta
8.0
Very good
7,895 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,895 reviews
Delta
8.0
Very good
7,895 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,605 reviews
Delta
8.0
Very good
7,895 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,895 reviews

Comfort

8.0

Entertainment

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Buffalo to Knoxville round-trip?

    Our cheapest airline available from Buffalo to Knoxville is American Airlines. Our recent data shows that you can find tickets from as low as $199 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $243 and $264 round-trip. American Airlines is 38% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Buffalo to Knoxville that include hotel bookings?

    Yes. In addition to deals on Buffalo to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Knoxville.

  • Can I find deals for business class flights from Buffalo to Knoxville?

    Yes. Cheapflights offers flight deals from Buffalo to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Knoxville (average of $295). Flying from Buffalo to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 3 airlines flying from Buffalo to Knoxville

Discover the top 3 airlines that operate flights from Buffalo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$328FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$208Average$309FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$222Average$324FlexibilityNo cancel feeOn-time69%
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