What are the cheapest airlines flying from St. Louis to Key West round-trip?

Our cheapest airline available from St. Louis to Key West is Delta. Our recent data shows that you can find tickets from as low as $244 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $255 and $486 round-trip. Users have found that Delta is 47% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from St. Louis to Key West one-way?

To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $338. American Airlines flights start at $354 while deals on Delta start at $475 one-way.

What is the cheapest day to fly from St. Louis to Key West?

Travelers seeking maximum savings on their St. Louis to Key West flight should consider departing on Tuesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from St. Louis to Key West?

When booking a flight from St. Louis to Key West, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from St. Louis to Key West?

Flying to your destination on a Saturday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Key West. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from St. Louis to Key West?

To save up to 50% on this flight, we recommend booking at least 48 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from St. Louis to Key West from $378 1-2 weeks out and tickets from $554 for flights departing within the next 72 hours.

What is the cheapest month to fly from St. Louis to Key West?

The best pricing can be found in the month of February. Prices to Key West from St. Louis average $464. You can even find prices in February for less than $464, as users have found deals to Key West from as low as $249. The month of June appears to be one of the more expensive times to travel to Key West from St. Louis. Flying in the targeted month can save you up to 30%.

What is the cheapest time of day to fly from STL to EYW?

One of the essential ways to save on airfare from St. Louis to Key West is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight at noon could potentially save you up to 17% on airfare.

Most accurate provider : When it comes to deals on St. Louis-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Key West flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on St. Louis-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from St. Louis to Key West that include hotel bookings?

Yes. In addition to deals on St. Louis to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Key West?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Key West.

Can I find deals for business class flights from St. Louis to Key West?

Yes. Cheapflights offers flight deals from St. Louis to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$244+ Flights from St. Louis to Key West

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Lambert-St Louis to Key West are usually found in February or January, booked 63 days in advance, depart on a Friday or Tuesday and return on a Wednesday

Cheap flight deals from St. Louis to Key West

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$244 (Delta)
Popular in	June
Cheapest in	February
Average price	$428

Provider with most accurate pricing for Lambert-St Louis-Key West flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Key West flights.

Search Deals

From Lambert-St Louis to Key West

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($26 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

Search Deals

Find flight deals from St. Louis to Key West

Cheapest flights from St. Louis to Key West
Explore the most affordable flight options available from St. Louis to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

Sun 5/251:09 pmSTL - EYW

1 stop5h 58mDelta

Tue 6/36:25 pmEYW - STL

1 stop6h 13mDelta

Deal found 4/10

$244

Fri 8/225:30 amSTL - EYW

1 stop7h 03mAmerican Airlines

Wed 8/274:05 pmEYW - STL

1 stop7h 25mAmerican Airlines

Deal found 4/10

$255

Sat 5/249:50 amSTL - EYW

3 stops21h 13mMultiple Airlines

Sat 5/313:52 pmEYW - STL

3 stops27h 49mMultiple Airlines

Deal found 4/10

$435

Sun 7/278:00 amSTL - EYW

2 stops23h 00mUnited Airlines

Fri 8/16:45 pmEYW - STL

2 stops20h 52mUnited Airlines

Deal found 4/10

$486

Best flights from St. Louis to Key West
Discover carefully curated flight deals from St. Louis to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2025.

Sun 5/251:09 pmSTL - EYW

1 stop5h 58mDelta

Tue 6/36:25 pmEYW - STL

1 stop6h 13mDelta

Deal found 4/10

$244

Fri 8/225:30 amSTL - EYW

1 stop7h 03mAmerican Airlines

Wed 8/274:05 pmEYW - STL

1 stop7h 25mAmerican Airlines

Deal found 4/10

$255

Sat 5/2410:10 amSTL - EYW

2 stops20h 53mMultiple Airlines

Sat 5/313:52 pmEYW - STL

3 stops27h 49mMultiple Airlines

Deal found 4/10

$399

Sun 7/278:00 amSTL - EYW

2 stops23h 00mUnited Airlines

Fri 8/16:45 pmEYW - STL

2 stops20h 52mUnited Airlines

Deal found 4/10

$486

Last-minute flights from St. Louis to Key West
Discover last-minute flight deals from St. Louis to Key West. Data last updated April 11, 2025 and is based on user searches.

Sat 4/196:00 amSTL - EYW

1 stop7h 05mDelta

Wed 4/2312:25 pmEYW - STL

1 stop6h 37mDelta

Deal found 4/10

$263

Sat 4/199:41 amSTL - EYW

1 stop5h 35mAmerican Airlines

Wed 4/2312:59 pmEYW - STL

1 stop7h 24mAmerican Airlines

Deal found 4/10

$284

Sat 4/198:40 amSTL - EYW

2 stops8h 25mUnited Airlines

Wed 4/238:45 amEYW - STL

2 stops9h 38mUnited Airlines

Deal found 4/10

$654

Tue 5/65:12 amSTL - EYW

1 stop5h 58mAmerican Airlines

Tue 5/135:24 pmEYW - STL

2 stops7h 27mAmerican Airlines

Deal found 4/10

$256

Fri 5/94:50 pmSTL - EYW

2 stops14h 10mUnited Airlines

Mon 5/122:45 pmEYW - STL

2 stops26h 04mUnited Airlines

Deal found 4/10

$512

Sat 5/249:50 amSTL - EYW

3 stops21h 13mMultiple Airlines

Sat 5/313:52 pmEYW - STL

3 stops27h 49mMultiple Airlines

Deal found 4/10

$435

Sun 5/251:09 pmSTL - EYW

1 stop5h 58mDelta

Tue 6/36:25 pmEYW - STL

1 stop6h 13mDelta

Deal found 4/10

$244

One-way flights from St. Louis to Key West
Search for one-way flight options from St. Louis to Key West. Find affordable one-way fares based on user searches. Data last updated April 11, 2025.

Fri 4/188:48 amSTL - EYW

2 stops29h 16mUnited Airlines

Deal found 4/10

$338

Fri 4/186:21 pmSTL - EYW

1 stop15h 08mAmerican Airlines

Deal found 4/10

$354

Tue 4/157:10 amSTL - EYW

1 stop5h 55mDelta

Deal found 4/10

$475

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Key West that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 5/25

1:09 pm-8:07 pm

1 stop5h 58m

Key West

Tue 6/3

6:25 pm-11:38 pm

1 stop6h 13m

$244

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Fri 8/22

5:30 am-1:33 pm

1 stop7h 03m

Key West

Wed 8/27

4:05 pm-10:30 pm

1 stop7h 25m

$255

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sat 5/24

10:10 am-8:03 am

2 stops20h 53m

Key West

Sat 5/31

3:52 pm-6:41 pm

3 stops27h 49m

$399

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Sun 7/27

8:00 am-8:00 am

2 stops23h 00m

Key West

Fri 8/1

6:45 pm-2:37 pm

2 stops20h 52m

$486

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Fri 4/18

8:48 am-3:04 pm

2 stops29h 16m

$338

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Fri 4/18

6:21 pm-10:29 am

1 stop15h 08m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/10

Compare providers for flights from St. Louis to Key West

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Key West in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on St. Louis-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Key West flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on St. Louis-Key West flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Key West

How far ahead should I book a flight from St. Louis to Key West?

Booking 63 days in advance of your planned departure date is, on average, the best time to get cheap flights from St. Louis to Key West. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from St. Louis to Key West?

Currently, August is the cheapest month in which you can book a flight from St. Louis to Key West (average of $328). Flying from St. Louis to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Key West by month

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

See what other customers who have flown with Delta, United Airlines and American Airlines from St. Louis to Key West have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,910 reviews

Reviews

1 / 20

2.0

Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Delta

8.0

Very good

7,910 reviews

Delta

8.0

Very good

7,910 reviews

Reviews

1 / 20

2.0

Mediocre

Mark,Jun 2024

SGF - ATL

United Airlines

7.4

Good

8,636 reviews

Delta

8.0

Very good

7,910 reviews

Reviews

1 / 20

2.0

Mediocre

Mark,Jun 2024

SGF - ATL

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,910 reviews

Reviews

1 / 20

2.0

Mediocre

Mark,Jun 2024

SGF - ATL

Related info for your journey

What are the cheapest airlines flying from St. Louis to Key West round-trip?
Our cheapest airline available from St. Louis to Key West is Delta. Our recent data shows that you can find tickets from as low as $244 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $255 and $486 round-trip. Users have found that Delta is 47% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from St. Louis to Key West one-way?
To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $338. American Airlines flights start at $354 while deals on Delta start at $475 one-way.
Can I find deals for flights from St. Louis to Key West that include hotel bookings?
Yes. In addition to deals on St. Louis to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Key West?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Key West.
Can I find deals for business class flights from St. Louis to Key West?
Yes. Cheapflights offers flight deals from St. Louis to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Key West?
Currently, August is the cheapest month in which you can book a flight from St. Louis to Key West (average of $328). Flying from St. Louis to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Other flights to Key West

Top 3 airlines flying from St. Louis to Key West

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$222	Average$433	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$228	Average$470	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$268	Average$536	FlexibilityNo cancel fee	On-time69%

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$244+ Cheap flights from St. Louis to Key West (STL - EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Key West with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Lambert-St Louis to Key West are usually found in February or January, booked 63 days in advance, depart on a Friday or Tuesday and return on a Wednesday

Cheap flight deals from St. Louis to Key West

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from St. Louis to Key West

Cheapest flights from St. Louis to Key WestExplore the most affordable flight options available from St. Louis to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

Explore the most affordable flight options available from St. Louis to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Key West that are best for you.

Compare providers for flights from St. Louis to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Key West in April.

Best time to book a flight from St. Louis to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Key West

How far ahead should I book a flight from St. Louis to Key West?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Key West. Price data was last updated on April 4, 2025.

What is the cheapest month to book a flight from St. Louis to Key West?

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

Reviews of airlines servicing Key West

See what other customers who have flown with Delta, United Airlines and American Airlines from St. Louis to Key West have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from St. Louis to Key West round-trip?

What are the cheapest airlines to fly from St. Louis to Key West one-way?

Can I find deals for flights from St. Louis to Key West that include hotel bookings?

How can I find direct flights from St. Louis to Key West?

Can I find deals for business class flights from St. Louis to Key West?

What is the cheapest month to book a flight from St. Louis to Key West?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Key West

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from St. Louis to Key West

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Cheapest flights from St. Louis to Key West
Explore the most affordable flight options available from St. Louis to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2025.