$103+ Cheap flights from South Carolina to Key West (EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Apr 6 — Apr 131
1 adult, Economy
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Find cheap flights from South Carolina to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Key West
Keep the following information in mind while searching for South Carolina to Key West flight deals. Data was last updated April 1, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $199 (Delta) |
One-way from | $103 (Mytrip) |
Popular in | March |
Cheapest in | August |
Average price | $488 |
Find flight deals from South Carolina to Key West
Cheapest flights from South Carolina to Key WestExplore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.
Explore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1612:00 pmGSP - EYW
1 stop5h 15mDelta
Tue 8/197:00 amEYW - GSP
1 stop6h 13mDelta
Deal found 3/31![Delta logo]()
$199
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/255:00 amMYR - EYW
1 stop7h 10mAmerican Airlines
Tue 6/35:24 pmEYW - MYR
1 stop5h 07mAmerican Airlines
Deal found 3/31![American Airlines logo]()
$200
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1611:18 amGSP - EYW
2 stops7h 09mAmerican Airlines
Tue 8/1912:10 pmEYW - GSP
1 stop5h 17mAmerican Airlines
Deal found 3/31![American Airlines logo]()
$204
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/29:45 pmGSP - EYW
1 stop17h 11mAllegiant Air
Thu 5/84:24 pmEYW - GSP
2 stops22h 41mAllegiant Air
Deal found 3/31![Allegiant Air logo]()
$267
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/221:25 pmCAE - EYW
1 stop3h 50mDelta
Mon 8/257:00 amEYW - CAE
1 stop5h 32mDelta
Deal found 3/31![Delta logo]()
$294
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/81:23 pmCLT - EYW
1 stop26h 10mMultiple Airlines
Tue 4/152:34 pmEYW - CLT
2 stops33h 53mMultiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$296
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/29:45 pmGSP - EYW
1 stop17h 11mMultiple Airlines
Thu 5/810:23 amEYW - GSP
3 stops28h 42mMultiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:30 amCHS - EYW
1 stop5h 29mDelta
Sat 10/46:00 pmEYW - CHS
1 stop5h 41mDelta
Deal found 3/31![Delta logo]()
$337
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2711:13 amCHS - EYW
2 stops7h 18mAmerican Airlines
Sat 10/46:01 pmEYW - CHS
1 stop4h 51mAmerican Airlines
Deal found 3/31![American Airlines logo]()
$342
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/42:10 pmMYR - EYW
1 stop6h 16mDelta
Tue 4/87:00 amEYW - MYR
1 stop6h 25mDelta
Deal found 3/31![Delta logo]()
$344
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:10 amMYR - EYW
2 stops10h 06mMultiple Airlines
Mon 6/210:23 amEYW - MYR
1 stop27h 33mMultiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$351
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/167:30 pmCHS - EYW
2 stops21h 19mMultiple Airlines
Sat 4/193:04 pmEYW - CHS
2 stops24h 02mMultiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$358
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.
Fly from
South Carolina
Fly to
Key West
Route
Depart
Return
Price
GreenvilleKey West
GSP - EYW
GSPEYW
Greenville
Sat 8/16
12:00 pm-5:15 pm
1 stop5h 15m
Key West
Tue 8/19
7:00 am-1:13 pm
1 stop6h 13m
$199
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Sun 5/25
5:00 am-12:10 pm
1 stop7h 10m
Key West
Tue 6/3
5:24 pm-10:31 pm
1 stop5h 07m
$200
GreenvilleKey West
GSP - EYW
GSPEYW
Greenville
Sat 8/16
11:18 am-6:27 pm
2 stops7h 09m
Key West
Tue 8/19
12:10 pm-5:27 pm
1 stop5h 17m
$204
GreenvilleKey West
GSP - EYW
GSPEYW
Greenville
Fri 5/2
9:45 pm-2:56 pm
1 stop17h 11m
Key West
Thu 5/8
4:24 pm-3:05 pm
2 stops22h 41m
$267
ColumbiaKey West
CAE - EYW
CAEEYW
Columbia Metropolitan
Fri 8/22
1:25 pm-5:15 pm
1 stop3h 50m
Key West
Mon 8/25
7:00 am-12:32 pm
1 stop5h 32m
$294
CharlotteKey West
CLT - EYW
CLTEYW
Charlotte Douglas
Tue 4/8
1:23 pm-3:33 pm
1 stop26h 10m
Key West
Tue 4/15
2:34 pm-12:27 am
2 stops33h 53m
$296
GreenvilleKey West
GSP - EYW
GSPEYW
Greenville
Fri 5/2
9:45 pm-2:56 pm
1 stop17h 11m
Key West
Thu 5/8
10:23 am-3:05 pm
3 stops28h 42m
$309
CharlestonKey West
CHS - EYW
CHSEYW
Charleston
Sat 9/27
5:35 am-11:14 am
1 stop5h 39m
Key West
Sat 10/4
6:01 pm-10:52 pm
1 stop4h 51m
$337
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Thu 5/29
5:10 am-3:16 pm
2 stops10h 06m
Key West
Mon 6/2
10:23 am-1:56 pm
1 stop27h 33m
$351
CharlestonKey West
CHS - EYW
CHSEYW
Charleston
Wed 4/16
7:30 pm-4:49 pm
2 stops21h 19m
Key West
Sat 4/19
3:04 pm-3:06 pm
2 stops24h 02m
$358
Showing 1-10 of 39 results
Best time to book a flight from South Carolina to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Key West
What is the cheapest month to book a flight from South Carolina to Key West?
Currently, August is the cheapest month in which you can book a flight from South Carolina to Key West (average of $328). Flying from South Carolina to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to EYW?
Find hourly flight availability from South Carolina to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Key West as you normally would.
Rainfall in Key West by month
Plan your trip to Key West by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.
Temperature in Key West by month
Plan your trip to Key West by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated April 1, 2025.
See what other customers who have flown with Breeze Airways, Delta and United Airlines from South Carolina to Key West have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.2
Food
6.7
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Comfort
8.2
Food
6.7
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Comfort
8.2
Food
6.7
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Comfort
8.2
Food
6.7
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Comfort
8.2
Food
6.7
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Comfort
8.2
Food
6.7
Overall
8.1
Boarding
8.3
Crew
8.8
Entertainment
6.6
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Key West
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from South Carolina to Key West
Discover the top 2 airlines that operate flights from South Carolina to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$441 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$488 | FlexibilityNo cancel fee | On-time71% |