$110+ Cheap flights from South Carolina to Key West (EYW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Apr 27 — May 41
1 adult, Economy
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Find cheap flights from South Carolina to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Key West
Keep the following information in mind while searching for South Carolina to Key West flight deals. Data was last updated April 22, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $204 (Kiwi.com) |
One-way from | $110 (Mytrip) |
Popular in | March |
Cheapest in | August |
Average price | $488 |
Find flight deals from South Carolina to Key West
Cheapest flights from South Carolina to Key WestExplore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.
Explore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/129:36 pmCHS - EYW
1 stop11h 46mBreeze Airways
Mon 6/162:07 pmEYW - CHS
1 stop18h 21mBreeze Airways
Deal found 4/21![Breeze Airways logo]()
$204
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:42 pmGSP - EYW
1 stop4h 02mDelta
Mon 9/292:35 pmEYW - GSP
1 stop6h 46mDelta
Deal found 4/21![Delta logo]()
$249
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1712:49 pmCAE - EYW
1 stop5h 41mAmerican Airlines
Mon 12/225:25 pmEYW - CAE
1 stop6h 09mAmerican Airlines
Deal found 4/22![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/275:00 amMYR - EYW
1 stop7h 10mAmerican Airlines
Fri 5/303:17 pmEYW - MYR
1 stop7h 14mAmerican Airlines
Deal found 4/22![American Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/65:54 amGSP - EYW
1 stop4h 56mAmerican Airlines
Wed 6/251:00 pmEYW - GSP
1 stop6h 50mAmerican Airlines
Deal found 4/22![American Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/264:00 pmAGS - EYW
1 stop3h 46mDelta
Sun 8/317:00 amEYW - AGS
1 stop4h 00mDelta
Deal found 4/22![Delta logo]()
$289
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/13:56 pmCHS - EYW
1 stop18h 24mMultiple Airlines
Thu 5/1510:30 amEYW - CHS
3 stops25h 03mMultiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/111:20 pmCAE - EYW
1 stop6h 24mDelta
Tue 10/147:00 amEYW - CAE
1 stop5h 28mDelta
Deal found 4/22![Delta logo]()
$299
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/299:04 amCLT - EYW
1 stop24h 29mMultiple Airlines
Thu 7/35:35 pmEYW - CLT
2 stops23h 02mMultiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$301
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/292:56 pmCHS - EYW
1 stop24h 26mAllegiant Air
Sun 6/18:53 amEYW - CHS
2 stops26h 52mAllegiant Air
Deal found 4/22![Allegiant Air logo]()
$314
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/279:25 amCHS - EYW
1 stop5h 39mAmerican Airlines
Sat 10/46:01 pmEYW - CHS
1 stop4h 51mAmerican Airlines
Deal found 4/21![American Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/265:27 amAGS - EYW
2 stops7h 34mAmerican Airlines
Sun 8/311:27 pmEYW - AGS
1 stop5h 43mAmerican Airlines
Deal found 4/22![American Airlines logo]()
$344
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from South Carolina to Key West that are best for you.
Fly from
South Carolina
Fly to
Key West
Route
Depart
Return
Price
CharlestonKey West
CHS - EYW
CHSEYW
Charleston
Thu 6/12
9:36 pm-9:22 am
1 stop11h 46m
Key West
Mon 6/16
2:07 pm-8:28 am
1 stop18h 21m
$204
GreenvilleKey West
GSP - EYW
GSPEYW
Greenville
Fri 9/26
3:42 pm-7:44 pm
1 stop4h 02m
Key West
Mon 9/29
2:35 pm-9:21 pm
1 stop6h 46m
$249
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Tue 5/27
5:00 am-12:10 pm
1 stop7h 10m
Key West
Fri 5/30
3:17 pm-10:31 pm
1 stop7h 14m
$275
GreenvilleKey West
GSP - EYW
GSPEYW
Greenville
Tue 5/6
5:54 am-10:50 am
1 stop4h 56m
Key West
Wed 6/25
1:00 pm-7:50 pm
1 stop6h 50m
$284
Myrtle BeachKey West
MYR - EYW
MYREYW
Myrtle Beach Intl
Fri 5/2
2:30 pm-8:30 pm
1 stop6h 00m
Key West
Fri 5/9
6:25 pm-11:59 pm
1 stop5h 34m
$284
AugustaKey West
AGS - EYW
AGSEYW
Augusta Bush Field
Tue 8/26
4:00 pm-7:46 pm
1 stop3h 46m
Key West
Sun 8/31
7:00 am-11:00 am
1 stop4h 00m
$289
CharlestonKey West
CHS - EYW
CHSEYW
Charleston
Thu 5/1
3:56 pm-10:20 am
1 stop18h 24m
Key West
Thu 5/15
10:30 am-11:33 am
3 stops25h 03m
$298
ColumbiaKey West
CAE - EYW
CAEEYW
Columbia Metropolitan
Sat 10/11
1:20 pm-7:44 pm
1 stop6h 24m
Key West
Tue 10/14
7:00 am-12:28 pm
1 stop5h 28m
$299
CharlotteKey West
CLT - EYW
CLTEYW
Charlotte Douglas
Sun 6/29
9:04 am-9:33 am
1 stop24h 29m
Key West
Thu 7/3
5:35 pm-4:37 pm
2 stops23h 02m
$301
CharlestonKey West
CHS - EYW
CHSEYW
Charleston
Thu 5/29
2:56 pm-3:22 pm
1 stop24h 26m
Key West
Sun 6/1
8:53 am-11:45 am
2 stops26h 52m
$314
Showing 1-10 of 40 results
Best time to book a flight from South Carolina to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Key West
What is the cheapest month to book a flight from South Carolina to Key West?
Currently, August is the cheapest month in which you can book a flight from South Carolina to Key West (average of $328). Flying from South Carolina to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to EYW?
Find hourly flight availability from South Carolina to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Key West as you normally would.
Rainfall in Key West by month
Plan your trip to Key West by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.
Temperature in Key West by month
Plan your trip to Key West by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).
Reviews of airlines servicing Key West
Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated April 22, 2025.
See what other customers who have flown with Breeze Airways, Delta and United Airlines from South Carolina to Key West have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.6
Crew
8.8
Food
6.7
Comfort
8.2
Boarding
8.3
Overall
8.1
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Crew
8.8
Food
6.7
Comfort
8.2
Boarding
8.3
Overall
8.1
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Crew
8.8
Food
6.7
Comfort
8.2
Boarding
8.3
Overall
8.1
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Crew
8.8
Food
6.7
Comfort
8.2
Boarding
8.3
Overall
8.1
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Crew
8.8
Food
6.7
Comfort
8.2
Boarding
8.3
Overall
8.1
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Entertainment
6.6
Crew
8.8
Food
6.7
Comfort
8.2
Boarding
8.3
Overall
8.1
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Key West
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from South Carolina to Key West
Discover the top 2 airlines that operate flights from South Carolina to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$428 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$483 | FlexibilityNo cancel fee | On-time71% |