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Key West

$149+ Cheap flights from South Carolina to Key West (EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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Cheap flight deals from South Carolina to Key West

Discover tips and strategies to find the most affordable flight options for your journey from South Carolina (USSC) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$199
(American Airlines)

One-way from

$149
(Mytrip)
From South Carolina to Key West
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One-way flight from South Carolina to Key West
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Find flight deals from South Carolina to Key West

Cheapest flights from South Carolina to Key West
Explore the most affordable flight options available from South Carolina to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/117:45 amGSP - EYW
1 stop4h 32mAmerican Airlines
Sat 2/157:29 pmEYW - GSP
1 stop5h 01mAmerican Airlines
Deal found 1/20$199
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/192:20 pmCLT - EYW
1 stop5h 51mDelta
Wed 2/266:14 pmEYW - CLT
1 stop3h 56mDelta
Deal found 1/20$219
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/66:54 pmCLT - EYW
1 stop14h 39mMultiple Airlines
Mon 2/105:55 pmEYW - CLT
2 stops23h 11mMultiple Airlines
Deal found 1/20$222
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/192:55 pmGSP - EYW
1 stop5h 35mDelta
Thu 3/276:15 pmEYW - GSP
1 stop5h 18mDelta
Deal found 1/20$224
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/212:59 pmCAE - EYW
1 stop4h 47mDelta
Wed 10/297:00 amEYW - CAE
1 stop4h 16mDelta
Deal found 1/19$249
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/213:07 pmAGS - EYW
1 stop5h 04mDelta
Thu 2/277:00 amEYW - AGS
1 stop4h 22mDelta
Deal found 1/21$253
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/226:28 amCLT - EYW
1 stop9h 41mUnited Airlines
Wed 2/2612:12 pmEYW - CLT
1 stop6h 34mUnited Airlines
Deal found 1/20$269
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/295:10 amMYR - EYW
1 stop6h 56mAmerican Airlines
Tue 5/63:05 pmEYW - MYR
1 stop6h 00mAmerican Airlines
Deal found 1/21$274
This Mytrip deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/232:52 pmMYR - EYW
2 stops18h 41mMultiple Airlines
Sun 4/275:39 pmEYW - MYR
2 stops23h 34mMultiple Airlines
Deal found 1/21$334
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/46:19 amCHS - EYW
1 stop9h 11mAmerican Airlines
Sat 2/87:29 pmEYW - CHS
1 stop4h 30mAmerican Airlines
Deal found 1/20$358
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:00 amGSP - EYW
1 stop5h 41mUnited Airlines
Wed 3/1212:45 pmEYW - GSP
1 stop6h 06mUnited Airlines
Deal found 1/20$369
This Mytrip deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/237:00 amCHS - EYW
1 stop8h 33mMultiple Airlines
Sun 4/275:39 pmEYW - CHS
2 stops22h 20mMultiple Airlines
Deal found 1/21$387

Find flights from South Carolina to Key West within your budget

Customize your flight search to find flights from South Carolina to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Tue 2/11

7:45 am-12:17 pm

1 stop4h 32m

Key West

Sat 2/15

7:29 pm-12:30 am

1 stop5h 01m

$199

CharlotteKey West

CLT - EYW

CLTEYW

Charlotte Douglas

Wed 2/19

2:20 pm-8:11 pm

1 stop5h 51m

Key West

Wed 2/26

6:14 pm-10:10 pm

1 stop3h 56m

$219

CharlotteKey West

CLT - EYW

CLTEYW

Charlotte Douglas

Thu 2/6

6:54 pm-9:33 am

1 stop14h 39m

Key West

Mon 2/10

5:55 pm-5:06 pm

2 stops23h 11m

$222

GreenvilleKey West

GSP - EYW

GSPEYW

Greenville

Wed 3/19

2:55 pm-8:30 pm

1 stop5h 35m

Key West

Thu 3/27

6:15 pm-11:33 pm

1 stop5h 18m

$224

AugustaKey West

AGS - EYW

AGSEYW

Augusta Bush Field

Fri 2/21

3:07 pm-8:11 pm

1 stop5h 04m

Key West

Thu 2/27

7:00 am-11:22 am

1 stop4h 22m

$253

CharlotteKey West

CLT - EYW

CLTEYW

Charlotte Douglas

Sat 2/22

6:28 am-4:09 pm

1 stop9h 41m

Key West

Wed 2/26

12:12 pm-6:46 pm

1 stop6h 34m

$269

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Tue 4/29

5:10 am-12:06 pm

1 stop6h 56m

Key West

Tue 5/6

3:05 pm-9:05 pm

1 stop6h 00m

$274

Myrtle BeachKey West

MYR - EYW

MYREYW

Myrtle Beach Intl

Wed 4/23

2:52 pm-9:33 am

2 stops18h 41m

Key West

Sun 4/27

5:39 pm-5:13 pm

2 stops23h 34m

$334

ColumbiaKey West

CAE - EYW

CAEEYW

Columbia Metropolitan

Tue 4/1

3:06 pm-8:30 pm

1 stop5h 24m

Key West

Tue 4/8

2:45 pm-8:02 pm

1 stop5h 17m

$344

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Thu 2/27

9:31 pm-9:03 am

1 stop11h 32m

Key West

Sun 3/2

5:27 pm-12:05 pm

2 stops18h 38m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 35 results
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Best time to book a flight from South Carolina to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Key West

Get recent, data-driven insights about flights from South Carolina to Key West including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Key West?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Key West (average of $328). Flying from South Carolina to Key West in March is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to EYW?

Find hourly flight availability from South Carolina to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Key West as you normally would.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated January 21, 2025.
See what other customers who have flown with American Airlines, United Airlines and Delta from South Carolina to Key West have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

On time flights; courteous staff; efficient boarding system! Thank you!

Delta
8.0
Very good
8,521 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

On time flights; courteous staff; efficient boarding system! Thank you!

United Airlines
7.4
Good
8,984 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

On time flights; courteous staff; efficient boarding system! Thank you!

Allegiant Air
7.4
Good
801 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

On time flights; courteous staff; efficient boarding system! Thank you!

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,521 reviews

Comfort

8.0

Food

7.3

Crew

8.6

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 10

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from South Carolina?

    For a flight from South Carolina to Key West, you will be flying into Key West. Key West (EYW) is just 2.6 mi from the center of the city.

  • What are the cheapest airlines to fly from South Carolina to Key West one-way?

    $149 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $173 and $179, respectively.

  • What are the most popular routes from South Carolina to Key West?

    When deciding which route to take from South Carolina to Key West consider Charlotte Douglas - Key West, Charleston - Key West or Columbia Metropolitan - Key West as they are the most popular.

  • Can I find deals for flights from South Carolina to Key West that include hotel bookings?

    Yes. In addition to deals on South Carolina to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Key West.

  • Can I find deals for business class flights from South Carolina to Key West?

    Yes. Cheapflights offers flight deals from South Carolina to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Key West?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Key West (average of $328). Flying from South Carolina to Key West in March is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from South Carolina to Key West

Discover the top 2 airlines that operate flights from South Carolina to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$456FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$245Average$498FlexibilityNo cancel feeOn-time71%
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