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Key West

$214+ Cheap flights from Missouri to Key West (EYW)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Missouri to Key West

Keep the following information in mind while searching for Missouri to Key West flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$214
(American Airlines)

Popular in

June

Cheapest in

August

Average price

$428
Provider with most accurate pricing for Kansas City-Key West flight deals.
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Provider most trusted by Cheapflights users for Kansas City-Key West flights.
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From Missouri to Key West
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($60 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Missouri to Key West

Cheapest flights from Missouri to Key West
Explore the most affordable flight options available from Missouri to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/17:00 amMCI - EYW
1 stop8h 07mAmerican Airlines
Wed 7/21:24 pmEYW - MCI
2 stops10h 49mAmerican Airlines
Deal found 4/17$214
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/146:00 amSTL - EYW
1 stop6h 39mAmerican Airlines
Wed 5/215:24 pmEYW - STL
1 stop5h 02mAmerican Airlines
Deal found 4/16$251
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:51 amSTL - EYW
1 stop6h 53mDelta
Tue 12/22:35 pmEYW - STL
1 stop4h 27mDelta
Deal found 4/16$259
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/256:31 pmMCI - EYW
1 stop14h 02mAllegiant Air
Thu 5/298:53 amEYW - MCI
1 stop9h 48mAllegiant Air
Deal found 4/17$269
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1711:26 amMCI - EYW
2 stops28h 19mMultiple Airlines
Thu 5/228:53 amEYW - MCI
1 stop9h 48mMultiple Airlines
Deal found 4/17$279
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2612:04 pmMCI - EYW
1 stop6h 35mDelta
Fri 7/47:10 amEYW - MCI
1 stop5h 58mDelta
Deal found 4/17$308
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/185:00 amSGF - EYW
2 stops8h 40mAmerican Airlines
Sat 8/233:03 pmEYW - SGF
1 stop7h 37mAmerican Airlines
Deal found 4/17$355
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/146:00 amMCI - EYW
2 stops25h 00mUnited Airlines
Tue 6/172:12 pmEYW - MCI
1 stop8h 58mUnited Airlines
Deal found 4/17$388
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/24:55 pmSGF - EYW
2 stops14h 05mUnited Airlines
Tue 5/68:45 amEYW - SGF
2 stops30h 20mUnited Airlines
Deal found 4/16$483
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/108:44 amSTL - EYW
2 stops23h 49mMultiple Airlines
Fri 8/151:47 pmEYW - STL
3 stops43h 02mMultiple Airlines
Deal found 4/17$535
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/208:00 amSTL - EYW
1 stop6h 04mUnited Airlines
Sat 4/268:45 amEYW - STL
2 stops12h 19mUnited Airlines
Deal found 4/17$539
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/212:08 pmSGF - EYW
1 stop7h 22mDelta
Tue 5/67:00 amEYW - SGF
1 stop5h 23mDelta
Deal found 4/16$599

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Missouri to Key West that are best for you.

Fly from

Missouri

Fly to

Key West

Route

Depart

Return

Price

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

Tue 7/1

7:00 am-4:07 pm

1 stop8h 07m

Key West

Wed 7/2

1:24 pm-11:50 pm

2 stops11h 26m

$214

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Tue 9/30

5:29 am-1:34 pm

1 stop7h 05m

Key West

Sat 10/4

7:31 pm-11:01 pm

1 stop4h 30m

$251

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

Sun 5/25

6:31 pm-9:33 am

1 stop14h 02m

Key West

Thu 5/29

8:53 am-5:41 pm

1 stop9h 48m

$269

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

Thu 6/26

12:04 pm-7:39 pm

1 stop6h 35m

Key West

Fri 7/4

2:05 pm-7:07 pm

1 stop6h 02m

$308

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Thu 8/28

1:30 pm-7:46 pm

1 stop5h 16m

Key West

Sun 8/31

7:00 am-12:24 pm

1 stop6h 24m

$314

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

Sun 5/25

6:31 pm-9:33 am

1 stop14h 02m

Key West

Thu 5/29

10:42 am-8:12 pm

2 stops34h 30m

$325

SpringfieldKey West

SGF - EYW

SGFEYW

Springfield-Branson

Mon 8/18

5:00 am-2:40 pm

2 stops8h 40m

Key West

Sat 8/23

3:03 pm-9:40 pm

1 stop7h 37m

$355

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

Sat 6/14

6:00 am-8:00 am

2 stops25h 00m

Key West

Tue 6/17

2:12 pm-10:10 pm

1 stop8h 58m

$388

SpringfieldKey West

SGF - EYW

SGFEYW

Springfield-Branson

Fri 5/2

4:55 pm-8:00 am

2 stops14h 05m

Key West

Tue 5/6

8:45 am-2:05 pm

2 stops30h 20m

$483

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

Mon 7/14

8:00 am-6:05 pm

2 stops9h 05m

Key West

Mon 7/21

6:45 pm-10:45 pm

2 stops29h 00m

$533

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 15 results
1
2

Best time to book a flight from Missouri to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Key West

What is the cheapest month to book a flight from Missouri to Key West?

Currently, August is the cheapest month in which you can book a flight from Missouri to Key West (average of $328). Flying from Missouri to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to EYW?

Find hourly flight availability from Missouri to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Missouri to Key West, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated April 17, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and Allegiant Air from Missouri to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Mark,Jun 2024

SGF - ATL

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Related info for your journey

Find useful and relevant information for your journey from Missouri to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from Missouri?

    Key West (EYW) is the airport you will fly into if you book a flight from Missouri to Key West. It is only a 2.6 mi journey from Key West (EYW) to Key West’s city center.

  • What are the most popular routes from Missouri to Key West?

    When deciding which route to take from Missouri to Key West consider Lambert-St Louis - Key West, Kansas City - Key West or Springfield-Branson - Key West as they are the most popular.

  • Can I find deals for flights from Missouri to Key West that include hotel bookings?

    Yes. In addition to deals on Missouri to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Key West.

  • Can I find deals for business class flights from Missouri to Key West?

    Yes. Cheapflights offers flight deals from Missouri to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Key West?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Key West (average of $328). Flying from Missouri to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Key West

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Top 3 airlines flying from Missouri to Key West

Discover the top 3 airlines that operate flights from Missouri to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$189Average$403FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$428FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$497FlexibilityNo cancel feeOn-time69%

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