Key West

$100+ Cheap flights from Missouri to Key West (EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — EYW
janv. 26 — févr. 21
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Key West with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Missouri (USMO) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated janvier 21, 2025.

Round-trip from

$204
(American Airlines)

One-way from

$100
(American Airlines)
From Missouri to Key West
One-way flight from Missouri to Key West

Find flight deals from Missouri to Key West

Cheapest flights from Missouri to Key West
Explore the most affordable flight options available from Missouri to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on janvier 21, 2025.

This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/47:03 amSGF - EYW
1 stop7h 40mAmerican Airlines
mer. 2/128:09 amEYW - SGF
2 stops9h 26mAmerican Airlines
Deal found 1/21$204
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/256:21 amMCI - EYW
1 stop6h 57mAmerican Airlines
mar. 3/47:29 pmEYW - MCI
1 stop6h 03mAmerican Airlines
Deal found 1/20$209
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/1512:30 pmMCI - EYW
1 stop6h 59mDelta
mar. 4/226:00 pmEYW - MCI
1 stop6h 56mDelta
Deal found 1/21$217
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/412:15 pmSGF - EYW
1 stop6h 56mDelta
mer. 2/126:16 pmEYW - SGF
1 stop5h 15mDelta
Deal found 1/21$217
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/11:30 pmSTL - EYW
1 stop5h 16mDelta
jeu. 7/107:00 amEYW - STL
1 stop6h 24mDelta
Deal found 1/20$259
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/1811:55 amSTL - EYW
1 stop5h 51mAmerican Airlines
mar. 2/254:59 pmEYW - STL
1 stop7h 57mAmerican Airlines
Deal found 1/20$269
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 3/16:10 amMCI - EYW
1 stop8h 59mUnited Airlines
mer. 3/54:07 pmEYW - MCI
1 stop6h 25mUnited Airlines
Deal found 1/20$301
This Trip.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 2/55:05 pmSTL - EYW
1 stop20h 15mMultiple Airlines
ven. 2/73:05 pmEYW - STL
1 stop9h 26mMultiple Airlines
Deal found 1/20$321
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/248:40 amSTL - EYW
1 stop6h 29mUnited Airlines
sam. 3/112:12 pmEYW - STL
2 stops10h 34mUnited Airlines
Deal found 1/20$390
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 2/211:05 amMCI - EYW
3 stops21h 28mMultiple Airlines
dim. 2/95:52 pmEYW - MCI
2 stops22h 03mMultiple Airlines
Deal found 1/20$405
This United deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 2/195:30 amSGF - EYW
2 stops12h 25mUnited Airlines
dim. 2/237:40 pmEYW - SGF
2 stops27h 04mUnited Airlines
Deal found 1/21$547

Find flights from Missouri to Key West within your budget

Customize your flight search to find flights from Missouri to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janvier 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

SpringfieldKey West

SGF - EYW

SGFEYW

Springfield-Branson

mar. 2/4

7:03 am-3:43 pm

1 stop7h 40m

Key West

mer. 2/12

8:09 am-4:35 pm

2 stops9h 26m

$204

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

mar. 2/25

6:21 am-2:18 pm

1 stop6h 57m

Key West

mar. 3/4

7:29 pm-12:32 am

1 stop6h 03m

$209

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

mar. 4/15

12:30 pm-8:29 pm

1 stop6h 59m

Key West

mar. 4/22

6:00 pm-11:56 pm

1 stop6h 56m

$217

SpringfieldKey West

SGF - EYW

SGFEYW

Springfield-Branson

mar. 2/4

12:15 pm-8:11 pm

1 stop6h 56m

Key West

mer. 2/12

6:16 pm-10:31 pm

1 stop5h 15m

$217

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

mar. 7/1

1:30 pm-7:46 pm

1 stop5h 16m

Key West

jeu. 7/10

7:00 am-12:24 pm

1 stop6h 24m

$259

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

mar. 2/18

11:55 am-6:46 pm

1 stop5h 51m

Key West

mar. 2/25

4:59 pm-11:56 pm

1 stop7h 57m

$269

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

sam. 3/1

6:10 am-4:09 pm

1 stop8h 59m

Key West

mer. 3/5

4:07 pm-9:32 pm

1 stop6h 25m

$301

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

mer. 2/5

5:05 pm-2:20 pm

1 stop20h 15m

Key West

ven. 2/7

3:05 pm-11:31 pm

1 stop9h 26m

$321

St. LouisKey West

STL - EYW

STLEYW

Lambert-St Louis

lun. 2/24

8:40 am-4:09 pm

1 stop6h 29m

Key West

sam. 3/1

12:12 pm-9:46 pm

2 stops10h 34m

$390

Kansas CityKey West

MCI - EYW

MCIEYW

Kansas City

dim. 5/4

6:14 pm-9:01 am

1 stop13h 47m

Key West

dim. 5/11

8:53 am-5:24 pm

1 stop9h 31m

$403

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from Missouri to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Key West

Get recent, data-driven insights about flights from Missouri to Key West including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Key West?

Currently, August is the cheapest month in which you can book a flight from Missouri to Key West (average of $328). Flying from Missouri to Key West in March is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to EYW?

Find hourly flight availability from Missouri to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated janvier 21, 2025.

When flying from Missouri to Key West, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated janvier 21, 2025.
Get a feel of what it's like to fly with American Airlines, Delta and United Airlines from Missouri to Key West by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.6

Comfort

8.0

Food

7.3

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

8.0
Very good
8,521 reviews
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.6

Comfort

8.0

Food

7.3

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

7.4
Good
8,985 reviews
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.6

Comfort

8.0

Food

7.3

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

7.4
Good
801 reviews
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.6

Comfort

8.0

Food

7.3

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

7.2
Good
10,000 reviews
8.0
Very good
8,521 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.6

Comfort

8.0

Food

7.3

Overall

8.0

Reviews

1 / 10

One of the worst flights ever. I got to the airport early for my 6:48 pm flight and tried to get on the 4:30 ish flight. The gate agent was one of the worst customer service people in my 20 yrs of flying Delta. Very rude and wouldn’t even talk to me about riding standby. Then flight took off 3 hrs late and when Landed in Atlanta, the gate people wouldn’t even try to get me on the plane. It was still there but door was closed. For all of my almost 2 million miles, the worst experience from Delta. I am highly disappointed as it was not my fault I have to sleep in Atlanta and not Jacksonville Florida

Related info for your journey

Find useful and relevant information for your journey from Missouri to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Key West from Missouri?

    Key West (EYW) is the airport you will fly into if you book a flight from Missouri to Key West. It is only a 2.6 mi journey from Key West (EYW) to Key West’s city center.

  • What are the cheapest airlines to fly from Missouri to Key West one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $100. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Missouri to Key West for a low price.

  • What are the most popular routes from Missouri to Key West?

  • Can I find deals for flights from Missouri to Key West that include hotel bookings?

    Yes. In addition to deals on Missouri to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Key West.

  • Can I find deals for business class flights from Missouri to Key West?

    Yes. Cheapflights offers flight deals from Missouri to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Key West?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Key West (average of $328). Flying from Missouri to Key West in March is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Key West

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Missouri to Key West

Discover the top 3 airlines that operate flights from Missouri to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janvier 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$465FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$224Average$431FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$517FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.