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$126+ Cheap flights from Knoxville to Key West (TYS - EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — EYW
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Key West are usually found in August or March, booked 48 days in advance, depart on a Wednesday or Thursday and return on a Monday

Cheap flight deals from Knoxville to Key West

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Key West (EYW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$248
(Mytrip)

One-way from

$126
(Mytrip)

Popular in

June

Cheapest in

August

Average price

$438
Provider with most accurate pricing for Knoxville McGhee Tyson-Key West flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Key West flights.
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From Knoxville McGhee Tyson to Key West
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One-way flight from Knoxville McGhee Tyson to Key West
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Highest demand for flights based on searches. 8% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Knoxville to Key West

Cheapest flights from Knoxville to Key West
Explore the most affordable flight options available from Knoxville to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/206:08 pmTYS - EYW
1 stop21h 05mAllegiant Air
Wed 6/254:49 pmEYW - TYS
1 stop18h 20mAllegiant Air
Deal found 4/22$248
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1312:08 pmTYS - EYW
1 stop5h 22mDelta
Tue 5/206:25 pmEYW - TYS
1 stop5h 26mDelta
Deal found 4/22$249
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/67:10 amTYS - EYW
1 stop5h 41mAmerican Airlines
Sat 10/47:31 pmEYW - TYS
1 stop3h 54mAmerican Airlines
Deal found 4/22$254
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/117:00 amTYS - EYW
2 stops25h 00mUnited Airlines
Mon 7/146:45 pmEYW - TYS
2 stops26h 12mUnited Airlines
Deal found 4/22$416
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/228:35 pmTYS - EYW
3 stops20h 06mMultiple Airlines
Thu 5/295:47 pmEYW - TYS
2 stops23h 17mMultiple Airlines
Deal found 4/22$495

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Knoxville to Key West that are best for you.

Fly from

Knoxville

Fly to

Key West

Route

Depart

Return

Price

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 6/20

6:08 pm-3:13 pm

1 stop21h 05m

Key West

Wed 6/25

4:49 pm-11:09 am

1 stop18h 20m

$248

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Tue 5/13

12:08 pm-5:30 pm

1 stop5h 22m

Key West

Tue 5/20

6:25 pm-11:51 pm

1 stop5h 26m

$249

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Tue 5/6

7:10 am-12:51 pm

1 stop5h 41m

Key West

Sat 10/4

7:31 pm-11:25 pm

1 stop3h 54m

$254

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Fri 7/11

7:00 am-8:00 am

2 stops25h 00m

Key West

Mon 7/14

6:45 pm-8:57 pm

2 stops26h 12m

$416

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 5/22

8:35 pm-4:41 pm

3 stops20h 06m

Key West

Thu 5/29

5:47 pm-5:04 pm

2 stops23h 17m

$495

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Tue 5/27

3:21 pm-2:13 pm

1 stop22h 52m

$126

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 6/5

4:22 pm-8:07 pm

1 stop3h 45m

$220

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Tue 5/27

6:51 am-4:52 pm

2 stops10h 01m

$225

KnoxvilleKey West

TYS - EYW

TYSEYW

Knoxville McGhee Tyson

Thu 5/22

8:35 pm-4:41 pm

3 stops20h 06m

$370

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Compare providers for flights from Knoxville to Key West

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Key West in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Key West flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Key West flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Key West flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Key West flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Key West flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Key West

How far ahead should I book a flight from Knoxville to Key West?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Key West. Price data was last updated on April 18, 2025.

To ensure you get the cheapest price possible for a flight from Knoxville to Key West, you should look to book at least 48 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Knoxville to Key West?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Key West (average of $328). Flying from Knoxville to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to EYW?

Find hourly flight availability from Knoxville to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Key West at noon. If you’re flexible enough to do this you can expect to save up to 30% on your trip compared to booking a flight in the morning.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated April 22, 2025.
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,683 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Key West round-trip?

    According to our current data, Allegiant Air ($248), Delta ($249), and American Airlines ($254) offers the cheapest pricing from Knoxville to Key West. Allegiant Air is currently priced 42% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Knoxville to Key West one-way?

    $126 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $220 and $225, respectively.

  • Can I find deals for flights from Knoxville to Key West that include hotel bookings?

    Yes. In addition to deals on Knoxville to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Key West.

  • Can I find deals for business class flights from Knoxville to Key West?

    Yes. Cheapflights offers flight deals from Knoxville to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Key West?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Key West (average of $328). Flying from Knoxville to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Key West

Discover the top 3 airlines that operate flights from Knoxville to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$78Average$142FlexibilityNo cancel feeOn-time88%
DeltaCheapest$208Average$473FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$439FlexibilityNo cancel feeOn-time71%

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