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$181+ Cheap flights from Iowa to Key West (EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Iowa to Key West

Keep the following information in mind while searching for Iowa to Key West flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$217
(Delta)

One-way from

$181
(American Airlines)

Popular in

June

Cheapest in

April

Average price

$581
Provider with most accurate pricing for Des Moines-Key West flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Key West flights.
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From Iowa to Key West
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One-way flight from Iowa to Key West
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Highest demand for flights based on searches. 9% potential increase in price ($42 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Iowa to Key West

Cheapest flights from Iowa to Key West
Explore the most affordable flight options available from Iowa to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/257:20 amDSM - EYW
2 stops10h 29mAmerican Airlines
Fri 5/3012:49 pmEYW - DSM
1 stop5h 54mAmerican Airlines
Deal found 3/31$214
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/711:17 amOMA - EYW
1 stop5h 13mDelta
Tue 5/136:25 pmEYW - OMA
1 stop6h 33mDelta
Deal found 3/30$217
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/76:35 amOMA - EYW
2 stops9h 17mAmerican Airlines
Tue 5/1312:50 pmEYW - OMA
2 stops10h 47mAmerican Airlines
Deal found 3/30$219
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/307:11 amCID - EYW
1 stop6h 53mAmerican Airlines
Tue 10/75:16 pmEYW - CID
1 stop5h 16mAmerican Airlines
Deal found 3/30$244
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/276:00 amMLI - EYW
1 stop5h 56mDelta
Tue 6/36:25 pmEYW - MLI
1 stop5h 32mDelta
Deal found 3/30$268
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/146:30 amDSM - EYW
2 stops30h 14mAllegiant Air
Fri 4/185:10 pmEYW - DSM
1 stop21h 48mAllegiant Air
Deal found 3/30$288
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/255:00 amMLI - EYW
1 stop6h 10mAmerican Airlines
Tue 6/35:24 pmEYW - MLI
1 stop5h 50mAmerican Airlines
Deal found 3/31$289
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/262:15 pmDSM - EYW
1 stop5h 15mDelta
Wed 4/306:30 pmEYW - DSM
1 stop5h 08mDelta
Deal found 3/30$294
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/225:45 amCID - EYW
1 stop6h 24mDelta
Tue 7/296:00 pmEYW - CID
1 stop5h 55mDelta
Deal found 3/31$339
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/125:48 pmCID - EYW
1 stop13h 25mAllegiant Air
Tue 4/152:34 pmEYW - CID
2 stops18h 56mAllegiant Air
Deal found 3/31$340
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/296:30 amMLI - EYW
1 stop7h 34mUnited Airlines
Fri 5/26:45 pmEYW - MLI
3 stops23h 02mUnited Airlines
Deal found 3/30$399
This Mytrip deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/288:10 pmCID - EYW
3 stops19h 47mMultiple Airlines
Sun 6/18:53 amEYW - CID
1 stop10h 20mMultiple Airlines
Deal found 3/29$412

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Iowa to Key West that are best for you.

Fly from

Iowa

Fly to

Key West

Route

Depart

Return

Price

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Sun 5/25

7:20 am-6:49 pm

2 stops10h 29m

Key West

Fri 5/30

12:49 pm-5:43 pm

1 stop5h 54m

$214

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Wed 5/7

11:17 am-5:30 pm

1 stop5h 13m

Key West

Tue 5/13

6:25 pm-11:58 pm

1 stop6h 33m

$217

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Wed 5/7

6:35 am-4:52 pm

2 stops9h 17m

Key West

Tue 5/13

12:50 pm-10:37 pm

2 stops10h 47m

$219

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Tue 5/27

6:00 am-12:56 pm

1 stop5h 56m

Key West

Tue 6/3

6:25 pm-10:57 pm

1 stop5h 32m

$268

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Fri 5/9

7:11 am-2:37 pm

1 stop6h 26m

Key West

Tue 5/13

5:24 pm-10:03 pm

1 stop5h 39m

$274

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Mon 4/14

6:30 am-1:44 pm

2 stops30h 14m

Key West

Fri 4/18

5:10 pm-1:58 pm

1 stop21h 48m

$288

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Sun 5/25

5:00 am-12:10 pm

1 stop6h 10m

Key West

Tue 6/3

5:24 pm-10:14 pm

1 stop5h 50m

$289

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Sat 4/26

2:15 pm-8:30 pm

1 stop5h 15m

Key West

Wed 4/30

6:30 pm-10:38 pm

1 stop5h 08m

$294

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Sat 4/12

5:48 pm-8:13 am

1 stop13h 25m

Key West

Tue 4/15

2:34 pm-8:30 am

2 stops18h 56m

$340

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Tue 4/29

6:30 am-3:04 pm

1 stop7h 34m

Key West

Fri 5/2

6:45 pm-4:47 pm

3 stops23h 02m

$399

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 22 results
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Best time to book a flight from Iowa to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Key West

What is the cheapest month to book a flight from Iowa to Key West?

Currently, August is the cheapest month in which you can book a flight from Iowa to Key West (average of $328). Flying from Iowa to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to EYW?

Find hourly flight availability from Iowa to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

When flying from Iowa to Key West, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated March 31, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and Allegiant Air from Iowa to Key West by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,614 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
731 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.9

Comfort

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Iowa to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from Iowa?

    Located just 2.6 mi from the city center, Key West (EYW) is the airport most travelers will use when flying to Key West from Iowa.

  • What are the cheapest airlines to fly from Iowa to Key West one-way?

    $181 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Allegiant Air and Delta, with prices starting from $191 and $230, respectively.

  • What are the most popular routes from Iowa to Key West?

    While some choose either Omaha Eppley Airfield - Key West or Moline Quad-City - Key West, Des Moines - Key West is the most popular route from Iowa to Key West.

  • Can I find deals for flights from Iowa to Key West that include hotel bookings?

    Yes. In addition to deals on Iowa to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Key West.

  • Can I find deals for business class flights from Iowa to Key West?

    Yes. Cheapflights offers flight deals from Iowa to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Key West?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Key West (average of $328). Flying from Iowa to Key West in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Key West

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to Key West

Discover the top 4 airlines that operate flights from Iowa to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$96Average$254FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$238Average$409FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$444FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$281Average$554FlexibilityNo cancel feeOn-time69%
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