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$110+ Cheap flights from Iowa to Key West (EYW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — EYW
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Iowa to Key West

Keep the following information in mind while searching for Iowa to Key West flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$209
(American Airlines)

One-way from

$110
(American Airlines)

Popular in

June

Cheapest in

July

Average price

$478
Provider with most accurate pricing for Des Moines-Key West flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Key West flights.
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From Iowa to Key West
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One-way flight from Iowa to Key West
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Highest demand for flights based on searches. 9% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Iowa to Key West

Cheapest flights from Iowa to Key West
Explore the most affordable flight options available from Iowa to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/52:31 pmDSM - EYW
1 stop16h 32mAllegiant Air
Fri 3/75:08 pmEYW - DSM
1 stop6h 24mAllegiant Air
Deal found 2/20$252
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/222:09 pmDSM - EYW
1 stop5h 21mDelta
Wed 4/305:15 pmEYW - DSM
1 stop6h 32mDelta
Deal found 2/19$269
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:50 amOMA - EYW
1 stop7h 21mAmerican Airlines
Wed 11/122:23 pmEYW - OMA
1 stop6h 59mAmerican Airlines
Deal found 2/20$269
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/66:45 amCID - EYW
1 stop6h 22mAmerican Airlines
Sat 5/1011:28 amEYW - CID
2 stops12h 41mAmerican Airlines
Deal found 2/19$279
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/227:25 amDSM - EYW
2 stops10h 30mAmerican Airlines
Wed 4/3011:39 amEYW - DSM
2 stops11h 28mAmerican Airlines
Deal found 2/19$279
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/67:32 pmCID - EYW
1 stop12h 30mAllegiant Air
Mon 3/105:08 pmEYW - CID
1 stop24h 30mAllegiant Air
Deal found 2/19$309
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/95:55 amMLI - EYW
1 stop6h 14mDelta
Mon 5/126:00 pmEYW - MLI
1 stop5h 29mDelta
Deal found 2/20$379
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/53:46 pmDSM - EYW
3 stops24h 02mMultiple Airlines
Fri 3/75:08 pmEYW - DSM
1 stop6h 24mMultiple Airlines
Deal found 2/20$382
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/78:05 amCID - EYW
1 stop5h 58mUnited Airlines
Tue 3/113:59 pmEYW - CID
1 stop6h 37mUnited Airlines
Deal found 2/20$395
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:45 amCID - EYW
1 stop6h 24mDelta
Mon 12/86:00 pmEYW - CID
1 stop4h 50mDelta
Deal found 2/20$404
This United deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/910:55 amMLI - EYW
2 stops26h 25mUnited Airlines
Mon 5/1210:55 amEYW - MLI
2 stops29h 26mUnited Airlines
Deal found 2/20$455
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:00 amMLI - EYW
1 stop7h 13mAmerican Airlines
Mon 12/85:24 pmEYW - MLI
1 stop5h 21mAmerican Airlines
Deal found 2/20$459

Find flights from Iowa to Key West within your budget

Customize your flight search to find flights from Iowa to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Iowa

Fly to

Key West

Route

Depart

Return

Price

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Wed 3/5

2:31 pm-8:03 am

1 stop16h 32m

Key West

Fri 3/7

5:08 pm-10:32 pm

1 stop6h 24m

$252

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Tue 4/22

2:09 pm-8:30 pm

1 stop5h 21m

Key West

Wed 4/30

5:15 pm-10:47 pm

1 stop6h 32m

$269

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Tue 5/6

6:45 am-2:07 pm

1 stop6h 22m

Key West

Sat 5/10

11:28 am-11:09 pm

2 stops12h 41m

$279

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Tue 4/22

7:25 am-6:55 pm

2 stops10h 30m

Key West

Wed 4/30

11:39 am-10:07 pm

2 stops11h 28m

$279

OmahaKey West

OMA - EYW

OMAEYW

Omaha Eppley Airfield

Fri 4/4

7:05 am-6:55 pm

2 stops10h 50m

Key West

Wed 4/9

3:06 pm-10:31 pm

2 stops8h 25m

$304

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Thu 3/6

7:32 pm-9:02 am

1 stop12h 30m

Key West

Mon 3/10

5:08 pm-4:38 pm

1 stop24h 30m

$309

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Fri 5/9

5:55 am-1:09 pm

1 stop6h 14m

Key West

Mon 5/12

6:00 pm-10:29 pm

1 stop5h 29m

$379

Des MoinesKey West

DSM - EYW

DSMEYW

Des Moines

Wed 3/5

3:46 pm-4:48 pm

3 stops24h 02m

Key West

Fri 3/7

5:08 pm-10:32 pm

1 stop6h 24m

$382

Cedar RapidsKey West

CID - EYW

CIDEYW

Cedar Rapids

Fri 3/7

8:05 am-3:03 pm

1 stop5h 58m

Key West

Tue 3/11

3:59 pm-9:36 pm

1 stop6h 37m

$395

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Fri 5/9

10:55 am-2:20 pm

2 stops26h 25m

Key West

Mon 5/12

10:55 am-3:21 pm

2 stops29h 26m

$455

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 29 results
1
2
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Best time to book a flight from Iowa to Key West

Have a flexible travel schedule? Discover the best time to fly to Key West from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to Key West

Get recent, data-driven insights about flights from Iowa to Key West including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to Key West?

Currently, August is the cheapest month in which you can book a flight from Iowa to Key West (average of $328). Flying from Iowa to Key West in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to EYW?

Find hourly flight availability from Iowa to Key West. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Iowa to Key West, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Key West by month

Plan your trip to Key West by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key West ranges from 1.5 - 6.7 inches per month. September is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Key West when rainfall is around 1.5 in.

Temperature in Key West by month

Plan your trip to Key West by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key West, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Key West

Get insights into the airlines that provide service to Key West. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key West. Reviews last updated February 20, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and Allegiant Air from Iowa to Key West by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.3
Good
765 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Iowa to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Key West from Iowa?

    Located just 2.6 mi from the city center, Key West (EYW) is the airport most travelers will use when flying to Key West from Iowa.

  • What are the cheapest airlines to fly from Iowa to Key West one-way?

    $110 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Allegiant Air and Delta, with prices starting from $130 and $250, respectively.

  • What are the most popular routes from Iowa to Key West?

    While some choose either Omaha Eppley Airfield - Key West or Moline Quad-City - Key West, Des Moines - Key West is the most popular route from Iowa to Key West.

  • Can I find deals for flights from Iowa to Key West that include hotel bookings?

    Yes. In addition to deals on Iowa to Key West flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Key West?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Key West.

  • Can I find deals for business class flights from Iowa to Key West?

    Yes. Cheapflights offers flight deals from Iowa to Key West by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Key West?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Key West (average of $328). Flying from Iowa to Key West in March is currently the most expensive (average of $510). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Key West

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Key West

Discover the top 3 airlines that operate flights from Iowa to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$243Average$402FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$451FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$548FlexibilityNo cancel feeOn-time69%
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