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Key Largo

$64+ Cheap flights from Iowa to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MIA
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Iowa to Key Largo

Cheapest flights from Iowa to Key Largo
Explore the most affordable flight options available from Iowa to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Expedia deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:28 pmOMA - MIA
1 stop7h 18mFrontier
Mon 12/225:30 amMIA - OMA
1 stop11h 10mFrontier
Deal found 12/10$254
This Expedia deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:28 pmOMA - MIA
1 stop7h 18mFrontier
Fri 12/195:30 amMIA - OMA
1 stop11h 05mFrontier
Deal found 12/10$258
This Frontier deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:12 pmCID - MIA
1 stop8h 07mFrontier
Wed 12/246:05 amMIA - CID
1 stop13h 48mFrontier
Deal found 12/11$267
This Frontier deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:35 pmOMA - MIA
1 stop7h 16mFrontier
Fri 1/95:20 amMIA - OMA
1 stop12h 45mFrontier
Deal found 12/10$268
This Expedia deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:48 pmCID - MIA
1 stop8h 12mFrontier
Mon 12/296:05 amMIA - CID
1 stop13h 48mFrontier
Deal found 12/9$304
This eDestinos deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:35 pmOMA - MIA
1 stop17h 23mFrontier
Sat 1/105:20 amMIA - OMA
2 stops31h 56mFrontier
Deal found 12/10$305
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:27 pmCID - MIA
1 stop7h 18mAmerican Airlines
Wed 1/75:36 pmMIA - CID
1 stop6h 29mAmerican Airlines
Deal found 12/10$316
This eDestinos deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:35 pmOMA - MIA
1 stop17h 23mFrontier
Sat 12/2710:19 pmMIA - OMA
2 stops36h 57mFrontier
Deal found 12/11$323
This Frontier deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:35 pmOMA - MIA
1 stop7h 16mFrontier
Mon 12/295:30 amMIA - OMA
1 stop11h 10mFrontier
Deal found 12/10$333
This Frontier deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:35 pmOMA - MIA
1 stop7h 12mFrontier
Fri 12/265:30 amMIA - OMA
1 stop11h 05mFrontier
Deal found 12/11$343
This Trip.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:24 pmOMA - MIA
1 stop13h 55mFrontier
Thu 12/186:05 amMIA - OMA
1 stop14h 42mFrontier
Deal found 12/11$355
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:43 pmMLI - MIA
1 stop6h 04mAmerican Airlines
Sun 12/287:10 amMIA - MLI
1 stop8h 41mAmerican Airlines
Deal found 12/10$374

Find flight deals from Iowa to Key Largo

Keep the following information in mind while searching for Iowa to Key Largo flight deals. Data was last updated December 12, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$190
(Frontier)

One-way from

$64
(Priceline)

Popular in

March

Cheapest in

June

Average price

$355
Provider with most accurate pricing for Des Moines-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Miami flights.
Search Deals
From Iowa to Key Largo
Search Deals
One-way flight from Iowa to Key Largo
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Iowa to Key Largo that are best for you.

Fly from

Iowa

Fly to

Key Largo

Route

Depart

Return

Price

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 1/10

5:40 pm-12:58 am

1 stop6h 18m

Miami

Sat 1/17

9:00 pm-11:59 pm

Nonstop3h 59m

$247

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Wed 1/14

5:16 pm-12:51 am

1 stop6h 35m

Miami

Wed 1/21

11:33 am-7:34 pm

1 stop9h 01m

$257

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Thu 1/15

3:58 pm-11:12 pm

1 stop6h 14m

Miami

Wed 1/21

3:54 pm-9:58 pm

1 stop7h 04m

$257

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 1/20

5:16 pm-12:51 am

1 stop6h 35m

Miami

Tue 1/27

5:50 am-10:41 am

1 stop5h 51m

$257

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sat 2/28

10:56 am-9:10 pm

1 stop9h 14m

Miami

Sat 3/7

6:00 am-12:14 pm

1 stop7h 14m

$257

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 1/21

5:52 am-3:40 pm

2 stops8h 48m

Miami

Wed 1/28

9:00 am-2:25 pm

1 stop6h 25m

$262

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Wed 1/21

10:55 am-10:00 pm

2 stops10h 05m

Miami

Sat 1/24

6:45 am-1:55 pm

1 stop8h 10m

$262

OmahaMiami

OMA - MIA

OMAMIA

Omaha Eppley Airfield

Sat 2/7

11:26 am-10:20 pm

2 stops9h 54m

Miami

Sat 2/14

9:00 am-2:26 pm

1 stop6h 26m

$262

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Fri 1/30

5:11 pm-12:51 am

1 stop6h 40m

Miami

Thu 2/26

10:33 am-4:18 pm

1 stop6h 45m

$269

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Sat 1/31

5:20 pm-12:51 am

1 stop6h 31m

Miami

Thu 2/26

10:33 am-4:18 pm

1 stop6h 45m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 60 results
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Best time to book a flight from Iowa to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Key Largo

What is the cheapest month to book a flight from Iowa to Key Largo?

Currently, August is the cheapest month in which you can book a flight from Iowa to Key Largo (average of $66). Flying from Iowa to Key Largo in September is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to KE9?

Find hourly flight availability from Iowa to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

When flying from Iowa to Key Largo, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 37% versus a flight in the morning.

What is the cheapest day to fly from Iowa to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Iowa to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Iowa to Key Largo flight should consider departing on Thursday evenings when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Key Largo?

    Airlines like American Airlines, Delta, and United Airlines fly from Iowa to Key Largo in about 6h 18m. The time it takes to get you to your destination can typically vary by up to 2h 30m. Iowa and Key Largo are separated by a distance of 1393 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Iowa to Key Largo?

    The most popular flight routes from Iowa to Key Largo are Omaha Eppley Airfield - Miami, Des Moines - Miami and Cedar Rapids - Miami.

  • What are the most reliable airlines from Iowa to Key Largo?

    Before booking your flight to Key Largo from Iowa, check out the most reliable airlines to get you to your destination on time: American Airlines (82%), Qatar Airways (82%), Envoy Air( 82%).

  • What are the cheapest flights from Iowa to Key Largo?

    The cheapest flight price from Iowa to Key Largo is $235. On average you can expect to pay $592. The most popular route, (Omaha Eppley Airfield - Miami), can usually be booked for $245.

  • Can I find deals for flights from Iowa to Key Largo that include hotel bookings?

    Yes. In addition to deals on Iowa to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Key Largo.

  • Can I find deals for business class flights from Iowa to Key Largo?

    Yes. Cheapflights offers flight deals from Iowa to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Key Largo?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Key Largo (average of $66). Flying from Iowa to Key Largo in September is currently the most expensive (average of $204). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Key Largo

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Top 6 airlines flying from Iowa to Key Largo

Discover the top 6 airlines that operate flights from Iowa to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$76Average$177FlexibilityNo cancel feeOn-time88%
FrontierCheapest$109Average$244FlexibilityNo cancel feeOn-time62%
DeltaCheapest$203Average$376FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$221Average$469FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$228Average$446FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$259Average$444FlexibilityNo cancel feeOn-time71%

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