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Key Largo

$75+ Cheap flights from Des Moines (DSM) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MIA
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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The best prices from Des Moines to Key Largo are usually found in September or May, booked 14 days in advance, depart on a Monday or Wednesday and return on a Wednesday

Cheap flight deals from Des Moines to Key Largo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Key Largo (KE9). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$248
(American Airlines)

One-way from

$75
(Frontier)

Popular in

March

Cheapest in

September

Average price

$412
From Des Moines to Key Largo
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One-way flight from Des Moines to Key Largo
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Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in January 2025
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Find flight deals from Des Moines to Key Largo

Cheapest flights from Des Moines to Key Largo
Explore the most affordable flight options available from Des Moines to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/912:25 pmDSM - MIA
1 stop8h 17mDelta
Wed 2/196:00 amMIA - DSM
1 stop5h 40mDelta
Deal found 1/21$256
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/411:35 amDSM - MIA
2 stops11h 24mUnited Airlines
Tue 2/113:47 pmMIA - DSM
1 stop9h 12mUnited Airlines
Deal found 1/21$271
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/96:45 amDSM - MIA
Nonstop3h 30mAmerican Airlines
Sat 8/167:45 pmMIA - DSM
Nonstop3h 31mAmerican Airlines
Deal found 1/20$290
This Southwest deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/36:10 amDSM - MIA
2 stops10h 25mSouthwest
Wed 3/126:15 pmMIA - DSM
1 stop5h 15mSouthwest
Deal found 1/21$295
This Frontier deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/178:41 pmDSM - MIA
1 stop7h 35mFrontier
Fri 2/216:25 amMIA - DSM
1 stop14h 16mFrontier
Deal found 1/21$296
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/32:41 pmDSM - MIA
2 stops21h 19mMultiple Airlines
Wed 2/57:52 amMIA - DSM
2 stops31h 53mMultiple Airlines
Deal found 1/20$318

Find flights from Des Moines to Key Largo within your budget

Customize your flight search to find flights from Des Moines to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Thu 3/27

2:07 pm-8:54 pm

1 stop5h 47m

Miami

Tue 4/1

7:39 pm-10:33 pm

Nonstop3h 54m

$248

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Mon 2/24

8:41 pm-5:16 am

1 stop7h 35m

Miami

Fri 2/28

6:25 am-7:41 pm

1 stop14h 16m

$250

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Sun 2/9

12:25 pm-9:42 pm

1 stop8h 17m

Miami

Wed 2/19

6:00 am-10:40 am

1 stop5h 40m

$256

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 2/4

8:00 am-5:06 pm

1 stop8h 06m

Miami

Tue 2/11

7:30 am-4:11 pm

1 stop9h 41m

$266

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Mon 3/3

6:10 am-5:35 pm

2 stops10h 25m

Miami

Wed 3/12

6:15 pm-10:30 pm

1 stop5h 15m

$295

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Mon 3/3

7:00 am-8:53 am

2 stops24h 53m

Miami

Wed 3/12

7:15 am-10:33 pm

2 stops16h 18m

$326

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Mon 2/24

8:41 pm-5:16 am

1 stop7h 35m

$75

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 3/25

6:00 am-10:19 am

Nonstop3h 19m

$119

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 2/11

6:26 pm-12:51 am

1 stop5h 25m

$129

Des MoinesMiami

DSM - MIA

DSMMIA

Des Moines

Tue 2/11

11:35 am-11:59 pm

2 stops11h 24m

$134

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 12 results
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Best time to book a flight from Des Moines to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Key Largo

Get recent, data-driven insights about flights from Des Moines to Key Largo including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Des Moines to Key Largo?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Key Largo. Price data was last updated on January 17, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Key Largo, you should look to book at least 14 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Key Largo?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Key Largo (average of $230). Flying from Des Moines to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to KE9?

Find hourly flight availability from Des Moines to Key Largo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from Des Moines to Key Largo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Des Moines to Key Largo?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Key Largo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to Key Largo flight should consider departing on Friday evenings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Des Moines to Key Largo

Explore weekly flight availability from Des Moines to Key Largo. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 21, 2025.

The most flights from DSM to KE9 are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Key Largo by month

Plan your trip to Key Largo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key Largo ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Key Largo when rainfall is around 1.6 in.

Temperature in Key Largo by month

Plan your trip to Key Largo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key Largo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated January 21, 2025.
Read through reviews of airlines operating flights from Des Moines to Key Largo, such as American Airlines, Delta and United Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Crew

8.7

Food

7.2

Comfort

8.1

Overall

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,662 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Crew

8.7

Food

7.2

Comfort

8.1

Overall

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,521 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Crew

8.7

Food

7.2

Comfort

8.1

Overall

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,984 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Crew

8.7

Food

7.2

Comfort

8.1

Overall

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Crew

8.7

Food

7.2

Comfort

8.1

Overall

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Frontier
6.1
Okay
3,443 reviews
Southwest
8.1
Very good
4,662 reviews

Boarding

8.2

Crew

8.7

Food

7.2

Comfort

8.1

Overall

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Key Largo?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Key Largo. 6 airlines have flights from Des Moines to Key Largo on a regular basis. Booking flights from Des Moines to Key Largo should not be difficult; the airport handles an average of 2 outbound flights to Key Largo per day.

  • What are the cheapest airlines to fly from Des Moines to Key Largo one-way?

    One-way options have recently been found by users for as low as $75 on Frontier. Other airlines that offer cheap prices include American Airlines from $119 and Delta from $129 one-way.

  • What are the most reliable airlines from Des Moines to Key Largo?

    Consider American Airlines (82%), Envoy Air (82%) or Qatar Airways (81%) when booking your flight. These represent the most reliable airlines when flying from Des Moines to Key Largo.

  • What are the cheapest flights from Des Moines to Key Largo?

    The cheapest flight price from Des Moines to Key Largo is $191. On average you can expect to pay $451. The most popular route, (Des Moines - Miami), can usually be booked for $209.

  • Can I find deals for flights from Des Moines to Key Largo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Key Largo.

  • Can I find deals for business class flights from Des Moines to Key Largo?

    Yes. Cheapflights offers flight deals from Des Moines to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Des Moines to Key Largo (average of $230). Flying from Des Moines to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Des Moines to Key Largo

Discover the top 6 airlines that operate flights from Des Moines to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$115Average$239FlexibilityNo cancel feeOn-time88%
FrontierCheapest$188Average$271FlexibilityNo cancel feeOn-time62%
DeltaCheapest$226Average$427FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$246Average$425FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$257Average$478FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$305Average$528FlexibilityNo cancel feeOn-time63%
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