What are the cheapest airlines to fly from South Carolina to Italy one-way?

$324 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Lufthansa and KLM, with prices starting from $390 and $401, respectively.

What is the cheapest month to fly from South Carolina to Italy?

February can be a great time to fly to Italy from South Carolina with a flight ticket averaging about $1,150. Cheapflights users have found deals in the month of February for as cheap as $691. The most expensive prices can be found in the month of June.

Can I find deals for flights from South Carolina to Italy that include hotel bookings?

Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Italy?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.

Can I find deals for business class flights from South Carolina to Italy?

Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$611+ Flights from South Carolina to Italy

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Cheap flight deals from South Carolina to Italy

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$630 (Mytrip)
One-way from	$272 (Kiwi.com)
Popular in	June
Cheapest in	February
Average price	$1,090

Provider with most accurate pricing for Myrtle Beach Intl-Rome (ROM) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Myrtle Beach Intl-Rome (ROM) flights.

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From South Carolina to Italy

Search Deals

One-way flight from South Carolina to Italy

Search Deals

Highest demand for flights based on searches. 29% potential increase in price ($481 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($55 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Find flight deals from South Carolina to Italy

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

Thu 10/231:02 pmCHS - FCO

1 stop19h 28mMultiple Airlines

Sat 11/16:10 pmFCO - CHS

1 stop23h 57mMultiple Airlines

Deal found 3/31

$561

Wed 11/56:37 pmCHS - VCE

2 stops18h 43mAmerican Airlines

Wed 11/126:20 amVCE - CHS

2 stops20h 18mAmerican Airlines

Deal found 4/1

$592

Wed 11/510:00 amCHS - VCE

3 stops21h 00mUnited Airlines

Wed 11/126:30 amVCE - CHS

2 stops18h 24mUnited Airlines

Deal found 4/1

$618

Mon 10/206:45 pmCLT - NAP

1 stop21h 15mBritish Airways

Mon 11/36:40 pmNAP - CLT

2 stops31h 00mBritish Airways

Deal found 3/31

$622

Mon 10/201:57 pmCHS - FCO

1 stop11h 38mUnited Airlines

Mon 11/37:05 amFCO - CHS

2 stops43h 59mUnited Airlines

Deal found 4/1

$624

Sat 10/256:32 pmCHS - FCO

2 stops44h 18mBritish Airways

Mon 11/108:45 pmFCO - CHS

2 stops28h 27mBritish Airways

Deal found 4/1

$627

Wed 5/75:45 amCLT - FCO

1 stop26h 45mMultiple Airlines

Wed 5/147:05 pmFCO - CLT

1 stop21h 23mMultiple Airlines

Deal found 4/1

$630

Sun 4/2711:30 pmCLT - NAP

1 stop16h 30mAmerican Airlines

Sat 5/103:00 pmNAP - CLT

1 stop23h 07mAmerican Airlines

Deal found 4/1

$640

Mon 10/207:05 amCLT - NAP

1 stop22h 35mMultiple Airlines

Mon 11/36:15 pmNAP - CLT

1 stop28h 40mMultiple Airlines

Deal found 3/31

$641

Sun 4/276:14 amCLT - NAP

2 stops18h 46mUnited Airlines

Sat 5/106:00 amNAP - CLT

1 stop16h 45mUnited Airlines

Deal found 4/1

$648

Wed 10/226:40 pmCLT - FLR

1 stop12h 15mLufthansa

Fri 10/316:30 amFLR - CLT

1 stop16h 25mLufthansa

Deal found 3/31

$659

Wed 10/2210:40 amCLT - FLR

2 stops24h 05mUnited Airlines

Fri 10/316:30 amFLR - CLT

1 stop16h 25mUnited Airlines

Deal found 3/31

$664

Best flights from South Carolina to Italy
Discover carefully curated flight deals from South Carolina to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2025.

Wed 5/75:45 amCLT - FCO

1 stop26h 45mMultiple Airlines

Wed 5/147:05 pmFCO - CLT

1 stop21h 23mMultiple Airlines

Deal found 4/1

$630

Sun 4/2711:30 pmCLT - NAP

1 stop16h 30mAmerican Airlines

Sat 5/103:00 pmNAP - CLT

1 stop23h 07mAmerican Airlines

Deal found 4/1

$640

Sun 4/276:14 amCLT - NAP

2 stops18h 46mUnited Airlines

Sat 5/106:00 amNAP - CLT

1 stop16h 45mUnited Airlines

Deal found 4/1

$648

Tue 8/1211:31 amCLT - NAP

1 stop16h 29mBritish Airways

Tue 8/2612:00 pmNAP - CLT

1 stop16h 46mBritish Airways

Deal found 3/31

$649

Tue 5/66:40 pmCLT - NAP

1 stop22h 15mLufthansa

Sat 5/179:00 amNAP - CLT

1 stop13h 45mLufthansa

Deal found 4/1

$669

Fri 4/2510:43 amCLT - NAP

2 stops40h 02mSWISS

Fri 5/29:35 amNAP - CLT

2 stops37h 10mSWISS

Deal found 3/31

$689

Sun 4/2010:48 amCLT - MXP

2 stops21h 12mAustrian Airlines

Mon 5/198:30 pmMXP - CLT

2 stops30h 51mAustrian Airlines

Deal found 4/1

$703

Tue 9/234:15 pmCLT - MXP

1 stop13h 50mKLM

Sat 10/49:20 amMXP - CLT

1 stop15h 16mKLM

Deal found 4/1

$710

Tue 9/167:30 pmCLT - FLR

2 stops15h 50mDelta

Thu 9/256:25 amFLR - CLT

2 stops18h 10mDelta

Deal found 3/31

$721

Mon 4/76:40 pmCLT - FCO

Nonstop9h 10mIberia

Mon 4/148:25 pmFCO - CLT

1 stop25h 50mIberia

Deal found 3/31

$730

Thu 5/16:00 amCLT - FCO

2 stops30h 45mScandinavian Airlines

Thu 5/157:35 pmFCO - CLT

2 stops32h 30mScandinavian Airlines

Deal found 3/31

$736

Sat 4/195:48 pmCLT - MXP

1 stop30h 57mAir France

Mon 5/197:20 pmMXP - CLT

2 stops27h 49mAir France

Deal found 4/1

$753

Last-minute flights from South Carolina to Italy
Discover last-minute flight deals from South Carolina to Italy. Data last updated April 2, 2025 and is based on user searches.

Tue 4/12:48 pmCLT - FCO

1 stop11h 27mUnited Airlines

Tue 4/811:30 amFCO - CLT

2 stops32h 37mUnited Airlines

Deal found 3/31

$679

Tue 4/14:16 pmCLT - FCO

1 stop13h 04mBritish Airways

Tue 4/812:10 pmFCO - CLT

Nonstop10h 40mBritish Airways

Deal found 3/31

$691

Wed 4/26:55 pmCLT - FCO

Nonstop8h 55mFinnair

Wed 4/912:10 pmFCO - CLT

Nonstop10h 40mFinnair

Deal found 4/1

$677

Mon 4/79:20 amCLT - FCO

1 stop18h 55mMultiple Airlines

Mon 4/148:10 pmFCO - CLT

2 stops31h 16mMultiple Airlines

Deal found 3/31

$713

Mon 4/711:25 amCLT - FCO

1 stop14h 10mUnited Airlines

Mon 4/1412:50 pmFCO - CLT

1 stop33h 55mUnited Airlines

Deal found 3/31

$714

Mon 4/76:40 pmCLT - FCO

Nonstop9h 10mIberia

Mon 4/148:25 pmFCO - CLT

1 stop25h 50mIberia

Deal found 3/31

$730

Mon 4/710:43 amCLT - FCO

2 stops27h 57mAustrian Airlines

Mon 4/149:30 pmFCO - CLT

2 stops29h 56mAustrian Airlines

Deal found 3/31

$732

Mon 4/72:40 pmCHS - FCO

1 stop11h 35mAustrian Airlines

Mon 4/143:00 pmFCO - CHS

2 stops34h 01mAustrian Airlines

Deal found 4/1

$751

Mon 4/710:36 amCHS - FCO

1 stop14h 59mDelta

Mon 4/149:45 amFCO - CHS

1 stop20h 13mDelta

Deal found 4/1

$762

Mon 4/76:40 pmCLT - FCO

Nonstop9h 10mFinnair

Mon 4/1412:10 pmFCO - CLT

Nonstop10h 40mFinnair

Deal found 3/31

$762

Mon 4/710:28 amCHS - FCO

3 stops27h 37mMultiple Airlines

Wed 5/710:35 pmFCO - CHS

3 stops29h 34mMultiple Airlines

Deal found 3/31

$777

Tue 4/81:06 pmSAV - FCO

1 stop13h 09mUnited Airlines

Mon 4/219:45 amFCO - SAV

1 stop17h 34mUnited Airlines

Deal found 4/1

$762

One-way flights from South Carolina to Italy
Search for one-way flight options from South Carolina to Italy. Find affordable one-way fares based on user searches. Data last updated April 2, 2025.

Sat 4/510:01 pmCLT - FCO

3 stops59h 59mMultiple Airlines

Deal found 3/31

$272

Sun 9/211:02 pmCHS - VCE

2 stops20h 58mMultiple Airlines

Deal found 4/1

$299

Sun 5/46:00 amCLT - FLR

3 stops58h 30mMultiple Airlines

Deal found 4/1

$302

Thu 4/248:35 pmCLT - MXP

2 stops38h 15mMultiple Airlines

Deal found 4/1

$306

Mon 6/3010:12 amCLT - MXP

1 stop14h 53mDelta

Deal found 4/1

$324

Sat 4/56:49 amCHS - FCO

2 stops28h 06mMultiple Airlines

Deal found 4/1

$339

Mon 6/302:28 pmCLT - LIN

2 stops14h 52mDelta

Deal found 4/1

$341

Tue 5/135:45 amCLT - LIN

3 stops30h 55mMultiple Airlines

Deal found 4/1

$354

Mon 6/306:40 pmCLT - LIN

1 stop17h 10mLufthansa

Deal found 4/1

$390

Tue 5/131:21 pmCLT - MXP

1 stop11h 24mKLM

Deal found 4/1

$401

Sat 5/171:21 pmCLT - LIN

2 stops14h 44mKLM

Deal found 4/1

$423

Sat 5/108:05 pmCLT - LIN

1 stop12h 55mAmerican Airlines

Deal found 3/31

$449

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteRome

CLT - FCO

CLTFCO

Charlotte Douglas

Wed 5/7

5:45 am-2:30 pm

1 stop26h 45m

Rome Fiumicino

Wed 5/14

7:05 pm-10:28 am

1 stop21h 23m

$630

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Sun 4/27

11:30 pm-10:00 pm

1 stop16h 30m

Naples

Sat 5/10

3:00 pm-8:07 am

1 stop23h 07m

$640

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Sun 4/27

6:14 am-7:00 am

2 stops18h 46m

Naples

Sat 5/10

6:00 am-4:45 pm

1 stop16h 45m

$648

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Tue 5/6

7:40 pm-10:55 pm

2 stops21h 15m

Naples

Sat 5/17

11:35 am-2:31 pm

2 stops32h 56m

$651

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Sun 4/27

2:40 pm-10:00 pm

2 stops25h 20m

Naples

Sun 5/4

7:50 am-6:50 pm

1 stop17h 00m

$665

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Tue 5/6

6:40 pm-10:55 pm

1 stop22h 15m

Naples

Sat 5/17

9:00 am-4:45 pm

1 stop13h 45m

$669

CharlotteNaples

CLT - NAP

CLTNAP

Charlotte Douglas

Fri 4/25

10:43 am-8:45 am

2 stops40h 02m

Naples

Fri 5/2

9:35 am-4:45 pm

2 stops37h 10m

$689

CharlestonRome

CHS - FCO

CHSFCO

Charleston

Sat 5/17

6:00 am-12:30 pm

2 stops24h 30m

Rome Fiumicino

Sat 5/24

7:35 pm-10:09 pm

2 stops32h 34m

$689

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Sun 4/20

6:40 pm-5:50 pm

1 stop17h 10m

Milan Linate

Mon 5/19

6:30 pm-4:45 pm

1 stop28h 15m

$692

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Sun 4/20

6:40 pm-4:30 pm

1 stop15h 50m

Milan Malpensa

Mon 5/19

5:10 pm-4:45 pm

1 stop29h 35m

$692

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 60 results

...

Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Italy (average of $703). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IT?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Italy as you normally would.

Rainfall in Italy by month

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Read reviews from past customers who have flown Delta, KLM and Finnair from South Carolina to Italy. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,898 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

KLM

7.8

Good

1,323 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Finnair

7.6

Good

1,267 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Austrian Airlines

7.6

Good

771 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

SWISS

7.5

Good

1,572 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines to fly from South Carolina to Italy one-way?
$324 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Lufthansa and KLM, with prices starting from $390 and $401, respectively.
Can I find deals for flights from South Carolina to Italy that include hotel bookings?
Yes. In addition to deals on South Carolina to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Italy?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Italy.
Can I find deals for business class flights from South Carolina to Italy?
Yes. Cheapflights offers flight deals from South Carolina to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South Carolina to Italy?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Italy (average of $703). Flying from South Carolina to Italy in June is currently the most expensive (average of $1,273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 8 airlines flying from South Carolina to Italy

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$626	Average$1,194	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$628	Average$1,258	FlexibilityNo cancel fee	On-time71%
ITA Airways	Cheapest$642	Average$799	FlexibilityNo cancel fee	On-time81%
KLM	Cheapest$655	Average$1,143	FlexibilityNo cancel fee	On-time75%
United Airlines	Cheapest$665	Average$1,180	FlexibilityNo cancel fee	On-time69%
Lufthansa	Cheapest$782	Average$1,712	FlexibilityNo cancel fee	On-time76%
British Airways	Cheapest$811	Average$1,241	FlexibilityNo cancel fee	On-time70%
Air Canada	Cheapest$1,063	Average$1,188	FlexibilityNo cancel fee	On-time67%

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$272+ Cheap flights from South Carolina to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South Carolina to Italy with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from South Carolina to Italy

Keep the following information in mind while searching for South Carolina to Italy flight deals. Data was last updated April 2, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from South Carolina to Italy

Cheapest flights from South Carolina to ItalyExplore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Best time to book a flight from South Carolina to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Italy

What is the cheapest month to book a flight from South Carolina to Italy?

What is the cheapest time of day to fly from SC to IT?

Find hourly flight availability from South Carolina to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated April 2, 2025.

Read reviews from past customers who have flown Delta, KLM and Finnair from South Carolina to Italy. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines to fly from South Carolina to Italy one-way?

Can I find deals for flights from South Carolina to Italy that include hotel bookings?

How can I find direct flights from South Carolina to Italy?

Can I find deals for business class flights from South Carolina to Italy?

What is the cheapest month to book a flight from South Carolina to Italy?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Italy

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from South Carolina to Italy

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Travel Smart

Cheapest flights from South Carolina to Italy
Explore the most affordable flight options available from South Carolina to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.