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$540+ Cheap flights from Panama City (PTY) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
abr. 22 — abr. 291
mar. 4/22
mar. 4/29
1 adult, Economy
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Cheap flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated abril 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$680
(Mytrip)

One-way from

$540
(Air Europa)

Popular in

July

Cheapest in

March

Average price

$810
Provider with most accurate pricing for Panama City Tocumen Intl-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Rome (ROM) flights.
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From Panama City Tocumen Intl to Italy
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One-way flight from Panama City Tocumen Intl to Italy
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Highest demand for flights based on searches. 9% potential increase in price ($90 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 17, 2025.

This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/1611:05 amPTY - LIN
2 stops17h 15mMultiple Airlines
dom. 6/222:30 pmLIN - PTY
2 stops19h 10mMultiple Airlines
Deal found 4/17$680
This Turkish Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/219:55 pmPTY - MXP
1 stop33h 15mTurkish Airlines
mié. 5/286:50 amMXP - PTY
1 stop20h 10mTurkish Airlines
Deal found 4/16$691
This Turkish Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/289:55 pmPTY - FCO
1 stop37h 25mTurkish Airlines
vie. 6/67:00 amFCO - PTY
1 stop20h 00mTurkish Airlines
Deal found 4/17$729
This Condor deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Condor is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/1611:05 amPTY - MXP
1 stop13h 55mCondor
mié. 6/185:35 pmMXP - PTY
1 stop16h 05mCondor
Deal found 4/16$752
This Air Europa deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/198:25 pmPTY - MXP
1 stop13h 50mAir Europa
vie. 6/611:05 amMXP - PTY
1 stop14h 35mAir Europa
Deal found 4/16$766
This Air Europa deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/248:25 pmPTY - FCO
1 stop14h 00mAir Europa
jue. 6/126:25 pmFCO - PTY
1 stop31h 15mAir Europa
Deal found 4/17$784
This KLM deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/196:50 pmPTY - LIN
1 stop14h 05mKLM
dom. 6/86:40 amLIN - PTY
1 stop17h 10mKLM
Deal found 4/16$787
This Iberia deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/195:35 pmPTY - LIN
1 stop19h 00mIberia
jue. 5/298:20 pmLIN - PTY
1 stop26h 45mIberia
Deal found 4/17$808
This Turkish Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/49:55 pmPTY - TRN
1 stop37h 20mTurkish Airlines
mar. 6/1710:15 amTRN - PTY
2 stops39h 05mTurkish Airlines
Deal found 4/17$824
This KLM deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 6/17:55 pmPTY - NAP
1 stop15h 20mMultiple Airlines
sáb. 6/148:35 pmNAP - PTY
2 stops28h 10mMultiple Airlines
Deal found 4/17$850
This Air France deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/177:55 pmPTY - FCO
1 stop30h 00mMultiple Airlines
jue. 5/17:40 pmFCO - PTY
1 stop28h 10mMultiple Airlines
Deal found 4/17$862
This Air France deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/177:55 pmPTY - MXP
1 stop20h 05mAir France
vie. 6/2711:40 amMXP - PTY
1 stop38h 22mAir France
Deal found 4/17$864

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 17, 2025.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Panama City

Fly to

Italy

Route

Depart

Return

Price

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

lun. 6/16

11:05 am-11:20 am

2 stops17h 15m

Milan Linate

dom. 6/22

2:30 pm-2:40 am

2 stops19h 10m

$680

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

mié. 5/21

9:55 pm-2:10 pm

1 stop33h 15m

Milan Malpensa

mié. 5/28

6:50 am-8:00 pm

1 stop20h 10m

$691

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

mié. 5/28

9:55 pm-6:20 pm

1 stop37h 25m

Rome Fiumicino

vie. 6/6

7:00 am-8:00 pm

1 stop20h 00m

$729

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

lun. 6/16

11:05 am-8:00 am

1 stop13h 55m

Milan Malpensa

mié. 6/18

5:35 pm-2:40 am

1 stop16h 05m

$752

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

lun. 5/19

8:25 pm-5:15 pm

1 stop13h 50m

Milan Malpensa

mar. 6/10

11:05 am-6:40 pm

1 stop14h 35m

$766

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

sáb. 5/24

8:25 pm-5:25 pm

1 stop14h 00m

Rome Fiumicino

jue. 6/12

6:25 pm-6:40 pm

1 stop31h 15m

$784

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

lun. 5/19

6:50 pm-3:55 pm

1 stop14h 05m

Milan Linate

dom. 6/8

6:40 am-4:50 pm

1 stop17h 10m

$787

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

lun. 5/19

5:35 pm-7:35 pm

1 stop19h 00m

Milan Linate

jue. 5/29

8:20 pm-4:05 pm

1 stop26h 45m

$808

Panama CityTurin

PTY - TRN

PTYTRN

Panama City Tocumen Intl

mié. 6/4

9:55 pm-6:15 pm

1 stop37h 20m

Turin Citta Di Torino

mar. 6/17

10:15 am-6:20 pm

2 stops39h 05m

$824

Panama CityNaples

PTY - NAP

PTYNAP

Panama City Tocumen Intl

dom. 6/1

7:55 pm-6:15 pm

1 stop15h 20m

Naples

sáb. 6/14

8:35 pm-5:45 pm

2 stops28h 10m

$850

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 46 results
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Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City to Italy?

Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IT?

Find hourly flight availability from Panama City to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Italy as you normally would.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated abril 17, 2025.
Read through reviews of airlines operating flights from Panama City to Italy, such as Emirates, Delta and KLM. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Emirates
8.0
Very good
3,200 reviews

Comfort

8.0

Boarding

8.1

Crew

8.3

Food

7.8

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
Emirates
8.0
Very good
3,200 reviews
Emirates
8.0
Very good
3,200 reviews

Comfort

8.0

Boarding

8.1

Crew

8.3

Food

7.8

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
Delta
8.0
Very good
7,916 reviews
Emirates
8.0
Very good
3,200 reviews

Comfort

8.0

Boarding

8.1

Crew

8.3

Food

7.8

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
KLM
7.8
Good
1,327 reviews
Emirates
8.0
Very good
3,200 reviews

Comfort

8.0

Boarding

8.1

Crew

8.3

Food

7.8

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
Air France
7.5
Good
1,435 reviews
Emirates
8.0
Very good
3,200 reviews

Comfort

8.0

Boarding

8.1

Crew

8.3

Food

7.8

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.
United Airlines
7.4
Good
8,667 reviews
Emirates
8.0
Very good
3,200 reviews

Comfort

8.0

Boarding

8.1

Crew

8.3

Food

7.8

Entertainment

8.2

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Jun 2024

DXB - IAH

It was not a good experience the seats were small and uncomfortable the food was not good and they forgot to serve me my breakfast - there were 5 us in 2 rows that they just completely skipped us. Very disappointed.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Most people fly from Panama City Tocumen Intl (PTY) if they book a flight from Panama City to Italy. Panama City Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City to Italy one-way?

    For one-way options, check prices for Air Europa. According to our data, you can fly for as low as $540. Users have also found prices from $556 and $658 on Turkish Airlines and Iberia, respectively.

  • What are the most popular routes from Panama City to Italy?

    When deciding which route to take from Panama City to Italy consider Panama City Tocumen Intl - Milan Malpensa, Panama City Tocumen Intl - Rome Fiumicino or Panama City Tocumen Intl - Milan Linate as they are the most popular.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Italy?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Panama City to Italy

Discover the top 5 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
IberiaCheapest$696Average$882FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$709Average$937FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$763Average$880FlexibilityNo cancel feeOn-time69%
Air EuropaCheapest$771Average$903FlexibilityNo cancel feeOn-time83%
KLMCheapest$1,546Average$1,738FlexibilityNo cancel feeOn-time75%

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