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$539+ Cheap flights from Panama City (PTY) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — NAP
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Panama City to Italy

Keep the following information in mind while searching for Panama City to Italy flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$753
(Gotogate)

One-way from

$573
(Turkish Airlines)

Popular in

July

Cheapest in

March

Average price

$791
Provider with most accurate pricing for Panama City Tocumen Intl-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Rome (ROM) flights.
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From Panama City Tocumen Intl to Italy
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One-way flight from Panama City Tocumen Intl to Italy
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Highest demand for flights based on searches. 9% potential increase in price ($92 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Panama City to Italy

Cheapest flights from Panama City to Italy
Explore the most affordable flight options available from Panama City to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Gotogate deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/118:25 pmPTY - MXP
1 stop13h 50mAir Europa
Sun 5/1811:05 amMXP - PTY
1 stop14h 35mAir Europa
Deal found 3/27$753
This Gotogate deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/139:55 pmPTY - MXP
1 stop18h 50mTurkish Airlines
Thu 4/243:40 pmMXP - PTY
1 stop35h 20mTurkish Airlines
Deal found 3/27$763
This Air Europa deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:25 pmPTY - FCO
1 stop14h 00mAir Europa
Fri 10/176:25 pmFCO - PTY
1 stop31h 15mAir Europa
Deal found 3/27$780
This KLM deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:50 pmPTY - TRN
1 stop20h 50mMultiple Airlines
Tue 6/1710:35 amTRN - PTY
1 stop14h 10mMultiple Airlines
Deal found 3/27$780
This Air France deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/197:55 pmPTY - MXP
1 stop20h 05mAir France
Thu 5/296:50 amMXP - PTY
1 stop17h 55mAir France
Deal found 3/27$783
This KLM deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/276:50 pmPTY - LIN
1 stop32h 15mKLM
Tue 9/210:55 pmLIN - PTY
1 stop24h 55mKLM
Deal found 3/27$783
This KLM deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/177:55 pmPTY - FCO
1 stop16h 10mMultiple Airlines
Wed 5/2812:45 pmFCO - PTY
1 stop35h 05mMultiple Airlines
Deal found 3/27$791
This KLM deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:50 pmPTY - TRN
1 stop20h 50mKLM
Tue 6/176:35 amTRN - PTY
2 stops17h 15mKLM
Deal found 3/27$799
This KLM deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:55 pmPTY - LIN
1 stop16h 50mMultiple Airlines
Thu 6/1211:00 amLIN - PTY
1 stop36h 50mMultiple Airlines
Deal found 3/27$812
This Turkish Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/248:00 pmPTY - FCO
1 stop35h 20mTurkish Airlines
Sat 5/1010:45 amFCO - PTY
2 stops38h 35mTurkish Airlines
Deal found 3/27$817
This KLM deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/256:50 pmPTY - FCO
1 stop31h 35mKLM
Sun 6/86:30 amFCO - PTY
2 stops18h 15mKLM
Deal found 3/27$831
This KLM deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/27:55 pmPTY - NAP
1 stop19h 10mMultiple Airlines
Mon 6/167:15 pmNAP - PTY
2 stops28h 35mMultiple Airlines
Deal found 3/27$832

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Panama City to Italy that are best for you.

Fly from

Panama City

Fly to

Italy

Route

Depart

Return

Price

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Sun 5/11

8:25 pm-5:15 pm

1 stop13h 50m

Milan Malpensa

Sun 5/18

11:05 am-6:40 pm

1 stop14h 35m

$753

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Sun 4/13

9:55 pm-11:45 pm

1 stop18h 50m

Milan Malpensa

Thu 4/24

3:40 pm-8:00 pm

1 stop35h 20m

$763

Panama CityTurin

PTY - TRN

PTYTRN

Panama City Tocumen Intl

Wed 6/4

6:50 pm-10:40 pm

1 stop20h 50m

Turin Citta Di Torino

Tue 6/17

10:35 am-5:45 pm

1 stop14h 10m

$780

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Mon 5/19

7:55 pm-11:00 pm

1 stop20h 05m

Milan Malpensa

Thu 5/29

6:50 am-5:45 pm

1 stop17h 55m

$783

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Sun 7/27

6:50 pm-10:05 am

1 stop32h 15m

Milan Linate

Tue 9/2

10:55 pm-4:50 pm

1 stop24h 55m

$783

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sat 5/17

7:55 pm-7:05 pm

1 stop16h 10m

Rome Fiumicino

Wed 5/28

12:45 pm-4:50 pm

1 stop35h 05m

$791

Panama CityTurin

PTY - TRN

PTYTRN

Panama City Tocumen Intl

Wed 6/4

6:50 pm-10:40 pm

1 stop20h 50m

Turin Citta Di Torino

Tue 6/17

6:35 am-4:50 pm

2 stops17h 15m

$799

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Thu 5/8

7:55 pm-7:45 pm

1 stop16h 50m

Milan Linate

Thu 6/12

11:00 am-4:50 pm

1 stop36h 50m

$812

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Thu 4/24

8:00 pm-2:20 pm

1 stop35h 20m

Rome Fiumicino

Sat 5/10

10:45 am-6:20 pm

2 stops38h 35m

$817

Panama CityRome

PTY - FCO

PTYFCO

Panama City Tocumen Intl

Sun 5/25

6:50 pm-9:25 am

1 stop31h 35m

Rome Fiumicino

Sun 6/8

6:30 am-5:45 pm

2 stops18h 15m

$831

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 39 results
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Best time to book a flight from Panama City to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Italy

What is the cheapest month to book a flight from Panama City to Italy?

Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IT?

Find hourly flight availability from Panama City to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Italy as you normally would.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated March 28, 2025.
Read through reviews of airlines operating flights from Panama City to Italy, such as Delta, KLM and Air France. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Delta
8.0
Very good
7,896 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
KLM
7.8
Good
1,321 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Air France
7.4
Good
1,424 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.
Turkish Airlines
7.3
Good
3,744 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Santiago,Apr 2024

MCO - ATL

When I was going to board, one of the staff members told me that I could not board with my passport bag because it was tree items and I would need to check a bag. This was so stupid ! The bag was small. So I had to put my things in my pockets, put the funny bag inside the other bag. Then go throw it. Then in the plane put everything back again in my funny bag.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Italy?

    Most people fly from Panama City Tocumen Intl (PTY) if they book a flight from Panama City to Italy. Panama City Tocumen Intl is conveniently located just 11.4 mi from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City to Italy one-way?

    For one-way options, check prices for Turkish Airlines. According to our data, you can fly for as low as $573. Users have also found prices from $791 and $857 on United Airlines and KLM, respectively.

  • What are the most popular routes from Panama City to Italy?

    When deciding which route to take from Panama City to Italy consider Panama City Tocumen Intl - Rome Fiumicino, Panama City Tocumen Intl - Trieste Ronchi dei Legionari or Panama City Tocumen Intl - Milan Malpensa as they are the most popular.

  • Can I find deals for flights from Panama City to Italy that include hotel bookings?

    Yes. In addition to deals on Panama City to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Italy.

  • Can I find deals for business class flights from Panama City to Italy?

    Yes. Cheapflights offers flight deals from Panama City to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Italy?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Italy (average of $703). Flying from Panama City to Italy in June is currently the most expensive (average of $1,279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Panama City to Italy

Discover the top 5 airlines that operate flights from Panama City to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$603Average$893FlexibilityNo cancel feeOn-time83%
IberiaCheapest$696Average$882FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$709Average$930FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$763Average$880FlexibilityNo cancel feeOn-time69%
KLMCheapest$1,546Average$1,738FlexibilityNo cancel feeOn-time75%
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