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$400+ Cheap flights from Knoxville (TYS) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — NAP
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Knoxville to Italy

Keep the following information in mind while searching for Knoxville to Italy flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$778
(United Airlines)

One-way from

$400
(Kiwi.com)

Popular in

May

Cheapest in

November

Average price

$1,088
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
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From Knoxville McGhee Tyson to Italy
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One-way flight from Knoxville McGhee Tyson to Italy
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Highest demand for flights based on searches. 15% potential increase in price ($200 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($34 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Knoxville to Italy

Cheapest flights from Knoxville to Italy
Explore the most affordable flight options available from Knoxville to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:50 amTYS - FCO
2 stops22h 10mUnited Airlines
Fri 11/2112:15 pmFCO - TYS
2 stops41h 27mUnited Airlines
Deal found 4/17$621
This Finnair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:56 amTYS - FCO
1 stop19h 04mMultiple Airlines
Fri 11/211:10 pmFCO - TYS
1 stop13h 26mMultiple Airlines
Deal found 4/17$682
This Gurufare deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:01 amTYS - FCO
1 stop15h 59mBritish Airways
Wed 12/311:10 pmFCO - TYS
1 stop34h 31mBritish Airways
Deal found 4/17$733
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/177:00 amTYS - MXP
2 stops21h 00mUnited Airlines
Wed 9/2412:15 pmMXP - TYS
2 stops40h 20mUnited Airlines
Deal found 4/17$778
This Booking.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:45 amTYS - MXP
3 stops22h 15mMultiple Airlines
Wed 9/2412:45 pmMXP - TYS
2 stops17h 12mMultiple Airlines
Deal found 4/17$817
This Gurufare deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:39 pmTYS - LIN
2 stops16h 36mBritish Airways
Wed 9/247:25 amLIN - TYS
2 stops16h 02mBritish Airways
Deal found 4/17$829
This Air Canada deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:45 amTYS - MXP
3 stops22h 15mAir Canada
Sun 9/2812:15 pmMXP - TYS
3 stops32h 35mAir Canada
Deal found 4/17$851
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/157:54 pmTYS - MXP
2 stops21h 46mAmerican Airlines
Thu 5/2211:10 amMXP - TYS
2 stops16h 45mAmerican Airlines
Deal found 4/17$855
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/96:58 pmTYS - VCE
1 stop30h 57mUnited Airlines
Sat 8/239:40 amVCE - TYS
1 stop17h 16mUnited Airlines
Deal found 4/17$863
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/12:50 pmTYS - FLR
2 stops23h 05mMultiple Airlines
Sun 10/129:00 amFLR - TYS
3 stops32h 55mMultiple Airlines
Deal found 4/17$877
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/178:45 pmTYS - LIN
2 stops15h 55mAmerican Airlines
Sun 9/287:25 amLIN - TYS
2 stops16h 02mAmerican Airlines
Deal found 4/17$889
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/34:50 pmTYS - FLR
2 stops41h 55mUnited Airlines
Sun 5/1110:30 amFLR - TYS
2 stops18h 15mUnited Airlines
Deal found 4/17$901

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Knoxville to Italy that are best for you.

Fly from

Knoxville

Fly to

Italy

Route

Depart

Return

Price

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Wed 9/17

7:00 am-10:00 am

2 stops21h 00m

Milan Malpensa

Wed 9/24

12:15 pm-10:35 pm

2 stops40h 20m

$778

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Wed 9/17

5:45 am-10:00 am

3 stops22h 15m

Milan Malpensa

Wed 9/24

12:45 pm-11:57 pm

2 stops17h 12m

$817

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Wed 9/17

6:39 pm-5:15 pm

2 stops16h 36m

Milan Linate

Wed 9/24

7:25 am-5:27 pm

2 stops16h 02m

$829

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Wed 9/17

5:45 am-10:00 am

3 stops22h 15m

Milan Malpensa

Sun 9/28

12:15 pm-2:50 pm

3 stops32h 35m

$851

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Thu 5/15

7:54 pm-11:40 pm

2 stops21h 46m

Milan Malpensa

Thu 5/22

11:10 am-9:55 pm

2 stops16h 45m

$855

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Sat 8/9

6:58 pm-7:55 am

1 stop30h 57m

Venice Marco Polo

Sat 8/23

9:40 am-8:56 pm

1 stop17h 16m

$863

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/1

2:50 pm-7:55 pm

2 stops23h 05m

Florence Peretola

Sun 10/12

9:00 am-11:55 am

3 stops32h 55m

$877

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 8/9

6:58 pm-7:55 am

2 stops30h 57m

Rome Fiumicino

Sat 8/23

10:20 am-10:42 pm

2 stops18h 22m

$878

KnoxvilleMilan

TYS - LIN

TYSLIN

Knoxville McGhee Tyson

Wed 9/17

8:45 pm-6:40 pm

2 stops15h 55m

Milan Linate

Sun 9/28

7:25 am-5:27 pm

2 stops16h 02m

$889

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sat 5/3

4:50 pm-4:45 pm

2 stops41h 55m

Florence Peretola

Sun 5/11

10:30 am-10:45 pm

2 stops18h 15m

$901

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 35 results
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Best time to book a flight from Knoxville to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Italy

What is the cheapest month to book a flight from Knoxville to Italy?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Italy (average of $703). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IT?

Find hourly flight availability from Knoxville to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Knoxville to Italy, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated April 17, 2025.
To help decide which airline to fly from Knoxville to Italy, see what other customers have to say about Delta, KLM and Air France. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,917 reviews
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,329 reviews
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air France
7.5
Good
1,435 reviews
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Scandinavian Airlines
7.3
Good
1,335 reviews
Delta
8.0
Very good
7,917 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Italy?

    For a flight from Knoxville to Italy, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • What are the cheapest airlines to fly from Knoxville to Italy one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $608. However, be on the lookout for offers from British Airways and Lufthansa, as they are both options that can get you from Knoxville to Italy for a low price.

  • What are the most popular routes from Knoxville to Italy?

    The most popular flight routes from Knoxville to Italy are Knoxville McGhee Tyson - Milan Malpensa, Knoxville McGhee Tyson - Milan Linate and Knoxville McGhee Tyson - Rome Fiumicino.

  • Can I find deals for flights from Knoxville to Italy that include hotel bookings?

    Yes. In addition to deals on Knoxville to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Italy.

  • Can I find deals for business class flights from Knoxville to Italy?

    Yes. Cheapflights offers flight deals from Knoxville to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Italy?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Italy (average of $703). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Knoxville to Italy

Discover the top 5 airlines that operate flights from Knoxville to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$575Average$1,123FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$610Average$937FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$671Average$1,307FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$678Average$1,189FlexibilityNo cancel feeOn-time76%
DeltaCheapest$730Average$1,247FlexibilityNo cancel feeOn-timeN/A

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