HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Italy

$464+ Cheap flights from Knoxville (TYS) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — NAP
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Italy with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Italy

Keep the following information in mind while searching for Knoxville to Italy flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$647
(AirNGo)

Popular in

May

Cheapest in

November

Average price

$935
Provider with most accurate pricing for Knoxville McGhee Tyson-Rome (ROM) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Rome (ROM) flights.
Search Deals
From Knoxville McGhee Tyson to Italy
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($177 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
Search Deals

Find flight deals from Knoxville to Italy

Cheapest flights from Knoxville to Italy
Explore the most affordable flight options available from Knoxville to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This United deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1210:16 amTYS - FCO
1 stop16h 14mUnited Airlines
Fri 11/2112:15 pmFCO - TYS
2 stops41h 27mUnited Airlines
Deal found 3/28$619
This AirNGo deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/77:29 pmTYS - VCE
1 stop34h 26mMultiple Airlines
Wed 4/2311:20 amVCE - TYS
1 stop18h 28mMultiple Airlines
Deal found 3/27$647
This AirNGo deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/75:00 pmTYS - VCE
1 stop12h 55mAir France
Wed 4/236:15 amVCE - TYS
2 stops18h 41mAir France
Deal found 3/27$656
This Finnair deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:56 amTYS - FCO
1 stop19h 04mMultiple Airlines
Fri 11/211:10 pmFCO - TYS
1 stop13h 26mMultiple Airlines
Deal found 3/27$670
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/710:06 amTYS - VCE
2 stops17h 14mDelta
Wed 4/236:15 amVCE - TYS
2 stops18h 41mDelta
Deal found 3/27$676
This Air Canada deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:50 amTYS - FCO
2 stops21h 25mAir Canada
Fri 10/2411:45 amFCO - TYS
2 stops41h 57mAir Canada
Deal found 3/27$704
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/136:30 amTYS - CTA
1 stop19h 25mDelta
Thu 10/239:55 amCTA - TYS
1 stop16h 57mDelta
Deal found 3/27$707
This FlightHub deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/184:00 pmTYS - MXP
2 stops36h 30mScandinavian Airlines
Mon 10/68:05 pmMXP - TYS
2 stops31h 40mScandinavian Airlines
Deal found 3/27$708
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/29:09 amTYS - FCO
1 stop18h 41mAmerican Airlines
Wed 4/911:05 amFCO - TYS
1 stop18h 25mAmerican Airlines
Deal found 3/27$742
This Gurufare deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:01 amTYS - FCO
1 stop15h 59mBritish Airways
Wed 12/311:10 pmFCO - TYS
1 stop13h 34mBritish Airways
Deal found 3/28$750
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:00 pmTYS - FCO
1 stop31h 55mDelta
Thu 10/239:45 amFCO - TYS
1 stop14h 32mDelta
Deal found 3/27$752
This United deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/42:20 pmTYS - MXP
2 stops20h 10mUnited Airlines
Fri 5/1612:15 pmMXP - TYS
2 stops34h 39mUnited Airlines
Deal found 3/26$771

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Knoxville to Italy that are best for you.

Fly from

Knoxville

Fly to

Italy

Route

Depart

Return

Price

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Mon 4/7

7:29 pm-11:55 am

1 stop34h 26m

Venice Marco Polo

Wed 4/23

11:20 am-11:48 pm

1 stop18h 28m

$647

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Mon 4/7

5:00 pm-11:55 am

1 stop12h 55m

Venice Marco Polo

Wed 4/23

6:15 am-6:56 pm

2 stops18h 41m

$656

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Mon 4/7

10:06 am-9:20 am

2 stops17h 14m

Venice Marco Polo

Wed 4/23

6:15 am-6:56 pm

2 stops18h 41m

$676

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Sun 5/4

2:20 pm-4:30 pm

2 stops20h 10m

Milan Malpensa

Fri 5/16

12:15 pm-4:54 pm

2 stops34h 39m

$771

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Fri 4/18

5:00 pm-11:55 am

1 stop12h 55m

Venice Marco Polo

Fri 4/25

11:20 am-9:29 pm

1 stop16h 09m

$786

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 4/21

1:57 pm-7:55 am

1 stop11h 58m

Rome Fiumicino

Tue 4/29

12:25 pm-10:22 pm

2 stops39h 57m

$795

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 9/3

4:00 pm-6:45 pm

2 stops20h 45m

Rome Fiumicino

Tue 9/16

7:35 pm-11:47 pm

2 stops34h 12m

$798

KnoxvilleVenice

TYS - VCE

TYSVCE

Knoxville McGhee Tyson

Fri 4/18

5:45 am-9:05 am

2 stops21h 20m

Venice Marco Polo

Fri 4/25

6:30 am-11:59 pm

2 stops23h 29m

$809

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Tue 4/29

6:25 pm-5:15 pm

2 stops16h 50m

Rome Fiumicino

Wed 5/21

11:05 am-7:25 pm

1 stop14h 20m

$816

KnoxvilleMilan

TYS - MXP

TYSMXP

Knoxville McGhee Tyson

Fri 5/9

9:55 am-10:00 am

2 stops42h 05m

Milan Malpensa

Tue 5/20

12:15 pm-2:35 pm

3 stops32h 20m

$823

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 38 results
1
2
3
4

Best time to book a flight from Knoxville to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Italy

What is the cheapest month to book a flight from Knoxville to Italy?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Italy (average of $703). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IT?

Find hourly flight availability from Knoxville to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Knoxville to Italy, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated March 28, 2025.
To help decide which airline to fly from Knoxville to Italy, see what other customers have to say about Delta, KLM and Finnair. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,896 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
KLM
7.8
Good
1,321 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Finnair
7.6
Good
1,267 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air France
7.4
Good
1,424 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Italy?

    For a flight from Knoxville to Italy, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • What are the cheapest airlines to fly from Knoxville to Italy one-way?

    The cheapest airline one-way is Lufthansa, with whom users have recently found tickets for as low as $1,511. However, be on the lookout for offers from Delta and British Airways, as they are both options that can get you from Knoxville to Italy for a low price.

  • What are the most popular routes from Knoxville to Italy?

    The most popular flight routes from Knoxville to Italy are Knoxville McGhee Tyson - Rome Fiumicino, Knoxville McGhee Tyson - Milan Malpensa and Knoxville McGhee Tyson - Milan Linate.

  • Can I find deals for flights from Knoxville to Italy that include hotel bookings?

    Yes. In addition to deals on Knoxville to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Italy.

  • Can I find deals for business class flights from Knoxville to Italy?

    Yes. Cheapflights offers flight deals from Knoxville to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Italy?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Italy (average of $703). Flying from Knoxville to Italy in June is currently the most expensive (average of $1,279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Italy

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Heathrow flights
Nashville to Gatwick flights
Nashville to Dublin flights
Nashville to Leonardo da Vinci/Fiumicino flights
Nashville to Frankfurt flights
Nashville to Charles de Gaulle flights
Nashville to Keflavik Intl flights
Nashville to London City flights
Nashville to Amsterdam flights
Nashville to Barcelona-El Prat flights
Nashville to Athens flights
Knoxville to Heathrow flights
Nashville to Orly flights
Memphis to Charles de Gaulle flights
Nashville to Lisbon flights
Nashville to Munich flights
Memphis to Heathrow flights
Nashville to Malpensa flights
Nashville to Stansted flights
Nashville to Vicenza flights
Memphis to Dublin flights
Nashville to Linate flights
Nashville to Florence flights
Knoxville to Dublin flights
Nashville to Zurich flights
Knoxville to London City flights
Nashville to Arlanda flights
Nashville to Madrid flights
Nashville to Naples flights
Memphis to Zurich flights
Memphis to Gatwick flights
Blountville to Amsterdam flights
Nashville to Edinburgh flights
Knoxville to Charles de Gaulle flights
Knoxville to Gatwick flights
Knoxville to Leonardo da Vinci/Fiumicino flights
Memphis to Athens flights
Nashville to Istanbul flights
Memphis to Frankfurt flights
Memphis to Barcelona-El Prat flights
Memphis to Copenhagen flights
Knoxville to Amsterdam flights
Knoxville to Athens flights
Nashville to Copenhagen flights
Nashville to Bruxelles-National flights
Knoxville to Edinburgh flights
Knoxville to Lisbon flights
Knoxville to Keflavik Intl flights
Nashville to Glasgow Intl flights
Chattanooga to Heathrow flights

Top 5 airlines flying from Knoxville to Italy

Discover the top 5 airlines that operate flights from Knoxville to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$575Average$1,154FlexibilityNo cancel feeOn-time69%
British AirwaysCheapest$610Average$1,098FlexibilityNo cancel feeOn-time70%
LufthansaCheapest$678Average$1,252FlexibilityNo cancel feeOn-time76%
DeltaCheapest$730Average$1,239FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$783Average$1,432FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.