What are the cheapest airlines to fly from Des Moines to Italy one-way?

The cheapest airline one-way is Aer Lingus, with whom users have recently found tickets for as low as $500. However, be on the lookout for offers from KLM and American Airlines, as they are both options that can get you from Des Moines to Italy for a low price.

What are the most popular routes from Des Moines to Italy?

While some choose either Des Moines - Venice Marco Polo or Des Moines - Milan Malpensa, Des Moines - Rome Fiumicino is the most popular route from Des Moines to Italy.

What is the cheapest month to fly from Des Moines to Italy?

November is one of the best times of the year to fly to Italy from Des Moines. Prices for November average $1,132 per person but you can even find prices for as low as $609. The most expensive prices can be found in the month of June. Opting for a November flight can save you 51% on your journey compared to booking in June

What airport do you fly from for flights from Des Moines to Italy?

For a flight from Des Moines to Italy, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

Can I find deals for flights from Des Moines to Italy that include hotel bookings?

Yes. In addition to deals on Des Moines to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Italy?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Italy.

Can I find deals for business class flights from Des Moines to Italy?

Yes. Cheapflights offers flight deals from Des Moines to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$871+ Flights from Des Moines to Italy

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Cheap flight deals from Des Moines to Italy

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$711 (United Airlines)
One-way from	$301 (Kiwi.com)
Popular in	June
Cheapest in	November
Average price	$1,039

Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.

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Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.

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From Des Moines to Italy

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One-way flight from Des Moines to Italy

Search Deals

Highest demand for flights based on searches. 25% potential increase in price ($377 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($54 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Find flight deals from Des Moines to Italy

Cheapest flights from Des Moines to Italy
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Sun 11/236:45 pmDSM - MXP

1 stop11h 05mUnited Airlines

Thu 12/1112:20 pmMXP - DSM

2 stops32h 51mUnited Airlines

Deal found 4/24

$548

Sun 11/236:45 pmDSM - MXP

2 stops32h 35mMultiple Airlines

Fri 12/121:05 pmMXP - DSM

3 stops35h 28mMultiple Airlines

Deal found 4/24

$555

Sat 11/226:45 pmDSM - MXP

3 stops56h 20mAir Canada

Fri 12/121:05 pmMXP - DSM

2 stops32h 06mAir Canada

Deal found 4/24

$560

Sun 11/236:45 pmDSM - LIN

2 stops15h 15mMultiple Airlines

Fri 12/126:15 amLIN - DSM

2 stops18h 18mMultiple Airlines

Deal found 4/24

$618

Sun 11/238:00 amDSM - FCO

1 stop16h 45mUnited Airlines

Wed 12/1012:15 pmFCO - DSM

2 stops29h 05mUnited Airlines

Deal found 4/24

$621

Sun 11/236:30 amDSM - VCE

1 stop21h 45mDelta

Thu 12/111:15 pmVCE - DSM

2 stops27h 07mDelta

Deal found 4/24

$632

Sun 11/236:45 pmDSM - LIN

2 stops16h 15mLufthansa

Mon 12/1510:35 amLIN - DSM

2 stops37h 58mLufthansa

Deal found 4/24

$634

Mon 11/248:00 amDSM - FCO

2 stops20h 05mAir Canada

Tue 12/91:15 pmFCO - DSM

2 stops31h 56mAir Canada

Deal found 4/24

$635

Sun 11/236:45 pmDSM - LIN

2 stops15h 15mUnited Airlines

Sat 12/136:15 amLIN - DSM

2 stops14h 56mUnited Airlines

Deal found 4/24

$638

Wed 11/265:45 amDSM - FCO

1 stop19h 10mDelta

Fri 12/129:20 amFCO - DSM

1 stop17h 38mDelta

Deal found 4/24

$644

Sun 11/238:00 amDSM - TRN

3 stops19h 05mAir Canada

Sat 12/136:00 amTRN - DSM

3 stops22h 36mAir Canada

Deal found 4/24

$659

Mon 10/275:45 amDSM - FCO

1 stop19h 10mKLM

Wed 11/510:00 amFCO - DSM

2 stops17h 50mKLM

Deal found 4/23

$660

Best flights from Des Moines to Italy
Discover carefully curated flight deals from Des Moines to Italy that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2025.

Wed 10/156:15 amDSM - FCO

2 stops18h 20mUnited Airlines

Fri 10/2411:45 amFCO - DSM

2 stops29h 54mUnited Airlines

Deal found 4/23

$711

Wed 10/156:00 amDSM - FCO

1 stop19h 20mAmerican Airlines

Fri 10/241:10 pmFCO - DSM

1 stop14h 22mAmerican Airlines

Deal found 4/23

$730

Wed 9/246:09 pmDSM - MXP

2 stops19h 41mMultiple Airlines

Tue 10/710:30 pmMXP - DSM

2 stops26h 33mMultiple Airlines

Deal found 4/22

$768

Wed 9/242:00 pmDSM - FCO

1 stop12h 10mIberia

Tue 10/76:25 amFCO - DSM

2 stops18h 38mIberia

Deal found 4/22

$773

Wed 9/246:00 amDSM - MXP

3 stops21h 00mAir Canada

Tue 10/712:15 pmMXP - DSM

3 stops31h 06mAir Canada

Deal found 4/22

$791

Tue 9/235:45 amDSM - FCO

1 stop18h 50mKLM

Tue 10/711:35 amFCO - DSM

1 stop17h 48mKLM

Deal found 4/22

$814

Tue 9/236:09 pmDSM - FCO

2 stops18h 46mBritish Airways

Thu 10/211:05 amFCO - DSM

1 stop13h 34mBritish Airways

Deal found 4/22

$818

Wed 9/242:14 pmDSM - MXP

2 stops35h 21mScandinavian Airlines

Mon 10/63:30 pmMXP - DSM

2 stops37h 53mScandinavian Airlines

Deal found 4/22

$827

Wed 9/249:32 amDSM - FCO

2 stops25h 28mFinnair

Mon 10/66:55 pmFCO - DSM

2 stops30h 32mFinnair

Deal found 4/22

$842

Tue 9/231:10 pmDSM - FCO

2 stops13h 50mLufthansa

Mon 10/66:55 pmFCO - DSM

2 stops29h 19mLufthansa

Deal found 4/22

$860

Thu 5/85:35 amDSM - FCO

2 stops19h 20mDelta

Thu 5/159:00 amFCO - DSM

1 stop14h 49mDelta

Deal found 4/23

$879

Thu 9/255:35 pmDSM - FCO

2 stops14h 15mAir France

Mon 10/69:45 amFCO - DSM

1 stop14h 54mAir France

Deal found 4/22

$1,003

Last-minute flights from Des Moines to Italy
Discover last-minute flight deals from Des Moines to Italy. Data last updated April 24, 2025 and is based on user searches.

Wed 4/2311:38 amDSM - FCO

1 stop13h 17mLufthansa

Tue 5/69:45 amFCO - DSM

1 stop15h 05mLufthansa

Deal found 4/23

$1,256

Thu 5/16:45 pmDSM - FLR

2 stops21h 00mLufthansa

Mon 5/55:25 pmFLR - DSM

2 stops31h 25mLufthansa

Deal found 4/23

$1,308

Thu 5/18:07 amDSM - FLR

3 stops18h 33mAir Canada

Mon 5/56:40 amFLR - DSM

3 stops22h 12mAir Canada

Deal found 4/23

$1,407

Thu 5/111:54 amDSM - FLR

2 stops16h 36mMultiple Airlines

Mon 5/52:40 pmFLR - DSM

3 stops34h 10mMultiple Airlines

Deal found 4/23

$3,343

Sun 5/42:15 pmDSM - FCO

1 stop13h 50mDelta

Fri 5/169:45 amFCO - DSM

1 stop15h 05mDelta

Deal found 4/23

$1,675

Sun 5/412:49 pmDSM - FCO

2 stops22h 11mFinnair

Wed 5/1410:00 amFCO - DSM

1 stop19h 50mFinnair

Deal found 4/23

$2,070

Wed 5/75:45 amDSM - FCO

1 stop23h 35mUnited Airlines

Wed 5/1411:30 amFCO - DSM

2 stops41h 22mUnited Airlines

Deal found 4/23

$792

Wed 5/78:07 amDSM - FCO

2 stops18h 08mMultiple Airlines

Wed 5/147:00 amFCO - DSM

3 stops17h 50mMultiple Airlines

Deal found 4/23

$924

Thu 5/85:45 amDSM - FCO

2 stops21h 30mAir Canada

Tue 5/1311:30 amFCO - DSM

2 stops43h 09mAir Canada

Deal found 4/23

$858

Thu 5/85:35 amDSM - FCO

1 stop22h 30mKLM

Wed 5/1411:35 amFCO - DSM

1 stop17h 55mKLM

Deal found 4/23

$875

Thu 5/85:35 amDSM - FCO

2 stops19h 20mDelta

Thu 5/159:00 amFCO - DSM

1 stop14h 49mDelta

Deal found 4/23

$879

Thu 5/81:12 pmDSM - FCO

1 stop35h 53mFinnair

Fri 5/1610:40 amFCO - DSM

2 stops19h 16mFinnair

Deal found 4/23

$1,163

One-way flights from Des Moines to Italy
Search for one-way flight options from Des Moines to Italy. Find affordable one-way fares based on user searches. Data last updated April 24, 2025.

Mon 9/228:00 amDSM - FCO

2 stops32h 45mMultiple Airlines

Deal found 4/23

$301

Tue 9/2310:03 amDSM - FCO

2 stops21h 27mAer Lingus

Deal found 4/23

$500

Tue 9/235:45 amDSM - FCO

1 stop18h 50mKLM

Deal found 4/23

$608

Sun 5/186:13 pmDSM - FCO

2 stops14h 42mAmerican Airlines

Deal found 4/23

$611

Sat 9/206:51 pmDSM - FCO

1 stop30h 04mUnited Airlines

Deal found 4/23

$620

Tue 9/238:00 amDSM - FCO

3 stops17h 50mAir Canada

Deal found 4/23

$634

Fri 5/1611:53 amDSM - VCE

2 stops18h 47mBritish Airways

Deal found 4/23

$637

Fri 5/168:07 amDSM - VCE

3 stops18h 43mAir Canada

Deal found 4/23

$659

Fri 5/211:54 amDSM - FLR

2 stops27h 26mBritish Airways

Deal found 4/23

$893

Fri 5/28:07 amDSM - FLR

3 stops18h 33mAir Canada

Deal found 4/23

$921

Fri 5/1611:26 amDSM - VCE

1 stop17h 29mKLM

Deal found 4/23

$1,375

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 10/15

6:15 am-7:35 am

2 stops18h 20m

Rome Fiumicino

Fri 10/24

11:45 am-10:39 am

2 stops29h 54m

$711

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 10/15

6:00 am-8:20 am

1 stop19h 20m

Rome Fiumicino

Fri 10/24

1:10 pm-8:32 pm

1 stop14h 22m

$730

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 9/24

6:09 pm-8:50 pm

2 stops19h 41m

Milan Malpensa

Tue 10/7

10:30 pm-6:03 pm

2 stops26h 33m

$768

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 9/24

2:00 pm-9:10 am

1 stop12h 10m

Rome Fiumicino

Tue 10/7

6:25 am-6:03 pm

2 stops18h 38m

$773

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 9/24

11:35 am-1:20 pm

1 stop18h 45m

Milan Malpensa

Tue 10/7

12:15 pm-5:14 pm

2 stops35h 59m

$778

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Wed 9/24

6:00 am-10:00 am

3 stops21h 00m

Milan Malpensa

Tue 10/7

12:15 pm-12:21 pm

3 stops31h 06m

$791

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 9/22

8:25 am-2:30 pm

1 stop23h 05m

Rome Fiumicino

Sun 10/5

7:05 pm-2:50 pm

1 stop26h 45m

$804

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 9/23

5:45 am-7:35 am

1 stop18h 50m

Rome Fiumicino

Tue 10/7

11:35 am-10:23 pm

1 stop17h 48m

$814

Des MoinesMilan

DSM - LIN

DSMLIN

Des Moines

Wed 9/24

6:09 pm-5:15 pm

2 stops16h 06m

Milan Linate

Tue 10/7

11:40 am-11:41 pm

2 stops19h 01m

$817

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 9/23

6:09 pm-7:55 pm

2 stops18h 46m

Rome Fiumicino

Thu 10/2

11:05 am-5:39 pm

1 stop13h 34m

$818

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 41 results

...

Best time to book a flight from Des Moines to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Italy

What is the cheapest month to book a flight from Des Moines to Italy?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $703). Flying from Des Moines to Italy in June is currently the most expensive (average of $1,273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IT?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Italy as you normally would.

Rainfall in Italy by month

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

To help decide which airline to fly from Des Moines to Italy, see what other customers have to say about Delta, KLM and Finnair. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,920 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

KLM

7.8

Good

1,333 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Finnair

7.6

Good

1,272 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Air France

7.4

Good

1,442 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,685 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly from for flights from Des Moines to Italy?
For a flight from Des Moines to Italy, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.
What are the cheapest airlines to fly from Des Moines to Italy one-way?
The cheapest airline one-way is Aer Lingus, with whom users have recently found tickets for as low as $500. However, be on the lookout for offers from KLM and American Airlines, as they are both options that can get you from Des Moines to Italy for a low price.
What are the most popular routes from Des Moines to Italy?
While some choose either Des Moines - Venice Marco Polo or Des Moines - Milan Malpensa, Des Moines - Rome Fiumicino is the most popular route from Des Moines to Italy.
Can I find deals for flights from Des Moines to Italy that include hotel bookings?
Yes. In addition to deals on Des Moines to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Italy?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Italy.
Can I find deals for business class flights from Des Moines to Italy?
Yes. Cheapflights offers flight deals from Des Moines to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Italy?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $703). Flying from Des Moines to Italy in June is currently the most expensive (average of $1,273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

Naples Airport car rentals

Venice Marco Polo Airport car rentals

Rome Fiumicino Airport car rentals

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Milan Malpensa Airport car rentals

Bologna Guglielmo Marconi Airport car rentals

Florence Peretola Airport car rentals

Palermo Punta Raisi Airport car rentals

Top 5 airlines flying from Des Moines to Italy

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$631	Average$1,174	FlexibilityNo cancel fee	On-timeN/A
KLM	Cheapest$668	Average$1,090	FlexibilityNo cancel fee	On-time75%
American Airlines	Cheapest$671	Average$1,219	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$688	Average$1,114	FlexibilityNo cancel fee	On-time69%
Lufthansa	Cheapest$811	Average$1,372	FlexibilityNo cancel fee	On-time76%

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$301+ Cheap flights from Des Moines (DSM) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Italy with Cheapflights

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Cheap flight deals from Des Moines to Italy

Keep the following information in mind while searching for Des Moines to Italy flight deals. Data was last updated April 24, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Italy

Cheapest flights from Des Moines to ItalyExplore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Italy that are best for you.

Best time to book a flight from Des Moines to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Italy

What is the cheapest month to book a flight from Des Moines to Italy?

What is the cheapest time of day to fly from DSM to IT?

Find hourly flight availability from Des Moines to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated April 24, 2025.

To help decide which airline to fly from Des Moines to Italy, see what other customers have to say about Delta, KLM and Finnair. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Italy?

What are the cheapest airlines to fly from Des Moines to Italy one-way?

What are the most popular routes from Des Moines to Italy?

Can I find deals for flights from Des Moines to Italy that include hotel bookings?

How can I find direct flights from Des Moines to Italy?

Can I find deals for business class flights from Des Moines to Italy?

What is the cheapest month to book a flight from Des Moines to Italy?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Italy

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Des Moines to Italy

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Cheapest flights from Des Moines to Italy
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.