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$602+ Cheap flights from Des Moines (DSM) to Italy

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — NAP
Mar 8 — Mar 151
Sat 3/8
Sat 3/15
1 adult, Economy
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Cheap flight deals from Des Moines to Italy

Keep the following information in mind while searching for Des Moines to Italy flight deals. Data was last updated March 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$638
(Gotogate)

One-way from

$602
(American Airlines)

Popular in

June

Cheapest in

November

Average price

$957
Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.
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From Des Moines to Italy
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One-way flight from Des Moines to Italy
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($428 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($52 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Des Moines to Italy

Cheapest flights from Des Moines to Italy
Explore the most affordable flight options available from Des Moines to Italy. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2025.

This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:45 pmDSM - FCO
2 stops32h 15mUnited Airlines
Wed 11/1912:15 pmFCO - DSM
2 stops42h 24mUnited Airlines
Deal found 3/2$617
This Gotogate deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:47 pmDSM - FCO
2 stops31h 28mAir Canada
Mon 4/711:30 amFCO - DSM
2 stops43h 12mAir Canada
Deal found 3/3$638
This Flighttix deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/88:00 amDSM - MXP
2 stops19h 00mAir Canada
Tue 4/1512:15 pmMXP - DSM
2 stops29h 25mAir Canada
Deal found 3/2$638
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/911:04 amDSM - FCO
1 stop13h 51mDelta
Wed 11/1910:15 amFCO - DSM
1 stop19h 07mDelta
Deal found 3/2$640
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2410:22 amDSM - FLR
2 stops23h 58mDelta
Mon 3/3112:10 pmFLR - DSM
2 stops37h 59mDelta
Deal found 3/3$645
This United deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/207:45 amDSM - TRN
2 stops22h 50mUnited Airlines
Thu 3/276:00 amTRN - DSM
2 stops21h 38mUnited Airlines
Deal found 3/2$653
This Booking.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:47 pmDSM - FCO
2 stops31h 28mMultiple Airlines
Mon 4/76:55 pmFCO - DSM
2 stops33h 57mMultiple Airlines
Deal found 3/2$653
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/711:38 amDSM - MXP
1 stop18h 42mUnited Airlines
Wed 4/2312:15 pmMXP - DSM
2 stops40h 37mUnited Airlines
Deal found 3/3$653
This Air Canada deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/78:00 amDSM - MXP
3 stops19h 00mMultiple Airlines
Wed 4/2312:15 pmMXP - DSM
2 stops29h 25mMultiple Airlines
Deal found 3/2$659
This KLM deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/111:27 amDSM - FCO
1 stop13h 08mKLM
Mon 4/79:45 amFCO - DSM
1 stop20h 14mKLM
Deal found 3/3$677
This KLM deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/85:45 amDSM - VCE
1 stop23h 10mKLM
Tue 4/156:00 amVCE - DSM
2 stops17h 38mKLM
Deal found 3/2$678
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/88:00 amDSM - VCE
2 stops18h 05mUnited Airlines
Tue 4/1511:05 amVCE - DSM
2 stops17h 47mUnited Airlines
Deal found 3/3$679

Find flights from Des Moines to Italy within your budget

Customize your flight search to find flights from Des Moines to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2025.

Fly from

Des Moines

Fly to

Italy

Route

Depart

Return

Price

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 4/1

6:47 pm-9:15 am

2 stops31h 28m

Rome Fiumicino

Mon 4/7

11:30 am-11:42 pm

2 stops43h 12m

$638

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Tue 4/8

8:00 am-10:00 am

2 stops19h 00m

Milan Malpensa

Tue 4/15

12:15 pm-10:40 am

2 stops29h 25m

$638

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 3/24

10:22 am-4:20 pm

2 stops23h 58m

Florence Peretola

Mon 3/31

12:10 pm-7:09 pm

2 stops37h 59m

$645

Des MoinesTurin

DSM - TRN

DSMTRN

Des Moines

Thu 3/20

7:45 am-12:35 pm

2 stops22h 50m

Turin Citta Di Torino

Thu 3/27

6:00 am-9:38 pm

2 stops21h 38m

$653

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 4/1

6:47 pm-9:15 am

2 stops31h 28m

Rome Fiumicino

Mon 4/7

6:55 pm-9:52 pm

2 stops33h 57m

$653

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Mon 4/7

6:47 pm-10:00 am

2 stops32h 13m

Milan Malpensa

Wed 4/23

12:15 pm-9:52 pm

2 stops40h 37m

$653

Des MoinesMilan

DSM - MXP

DSMMXP

Des Moines

Mon 4/7

8:00 am-10:00 am

3 stops19h 00m

Milan Malpensa

Wed 4/23

12:15 pm-10:40 am

2 stops29h 25m

$659

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 4/1

8:00 am-7:55 am

1 stop16h 55m

Rome Fiumicino

Mon 4/7

12:50 pm-6:06 pm

2 stops36h 16m

$662

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 4/1

11:56 am-9:10 am

1 stop14h 14m

Rome Fiumicino

Mon 4/7

8:30 pm-10:17 pm

2 stops32h 47m

$665

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 4/1

11:27 am-7:35 am

1 stop13h 08m

Rome Fiumicino

Mon 4/7

9:45 am-10:59 pm

1 stop20h 14m

$677

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/2

Showing 1-10 of 44 results
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Best time to book a flight from Des Moines to Italy

Have a flexible travel schedule? Discover the best time to fly to Italy from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Italy

Get recent, data-driven insights about flights from Des Moines to Italy including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to Italy?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $703). Flying from Des Moines to Italy in June is currently the most expensive (average of $1,286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IT?

Find hourly flight availability from Des Moines to Italy. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Italy as you normally would.

Rainfall in Italy by month

Plan your trip to Italy by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Italy ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Italy when rainfall is around 0.6 in.

Temperature in Italy by month

Plan your trip to Italy by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Italy, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Italy

Get insights into the airlines that provide service to Italy. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Italy. Reviews last updated March 3, 2025.
To help decide which airline to fly from Des Moines to Italy, see what other customers have to say about Delta, KLM and Austrian Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,068 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,068 reviews
Delta
8.0
Very good
8,068 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

KLM
7.8
Good
1,323 reviews
Delta
8.0
Very good
8,068 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Austrian Airlines
7.6
Good
768 reviews
Delta
8.0
Very good
8,068 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Air France
7.4
Good
1,437 reviews
Delta
8.0
Very good
8,068 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,679 reviews
Delta
8.0
Very good
8,068 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Italy. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Italy?

    For a flight from Des Moines to Italy, you will be flying from Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • What are the cheapest airlines to fly from Des Moines to Italy one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $602. However, be on the lookout for offers from Scandinavian Airlines and British Airways, as they are both options that can get you from Des Moines to Italy for a low price.

  • What are the most popular routes from Des Moines to Italy?

    While some choose either Des Moines - Venice Marco Polo or Des Moines - Milan Malpensa, Des Moines - Rome Fiumicino is the most popular route from Des Moines to Italy.

  • Can I find deals for flights from Des Moines to Italy that include hotel bookings?

    Yes. In addition to deals on Des Moines to Italy flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Italy?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Italy.

  • Can I find deals for business class flights from Des Moines to Italy?

    Yes. Cheapflights offers flight deals from Des Moines to Italy by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Italy?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Italy (average of $703). Flying from Des Moines to Italy in June is currently the most expensive (average of $1,286). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Italy

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Des Moines to Italy

Discover the top 5 airlines that operate flights from Des Moines to Italy. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$564Average$1,104FlexibilityNo cancel feeOn-time69%
KLMCheapest$668Average$1,100FlexibilityNo cancel feeOn-time75%
DeltaCheapest$690Average$1,311FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$719Average$1,143FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$891Average$1,464FlexibilityNo cancel feeOn-time76%
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