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$80+ Cheap flights from Des Moines (DSM) to Irvine, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LAX
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Irvine are usually found in May or January, booked 80 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Irvine

Cheapest flights from Des Moines to Irvine
Explore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:31 amDSM - LAX
2 stops25h 11mMultiple Airlines
Mon 12/295:59 pmLAX - DSM
1 stop19h 32mMultiple Airlines
Deal found 12/11$305
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:54 pmDSM - LAX
1 stop18h 34mMultiple Airlines
Thu 1/156:14 pmLAX - DSM
1 stop21h 10mMultiple Airlines
Deal found 12/11$326
This Frontier deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:29 pmDSM - LAX
1 stop6h 01mFrontier
Mon 1/126:26 amLAX - DSM
1 stop10h 56mFrontier
Deal found 12/10$362
This Frontier deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:29 pmDSM - LAX
1 stop6h 01mFrontier
Mon 1/56:34 amLAX - DSM
1 stop11h 10mFrontier
Deal found 12/11$363
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/193:15 pmDSM - LAX
Nonstop4h 07mAmerican Airlines
Thu 1/159:15 amLAX - DSM
Nonstop3h 35mAmerican Airlines
Deal found 12/11$373
This eDestinos deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:17 amDSM - LAX
3 stops31h 57mMultiple Airlines
Sun 12/2810:03 pmLAX - DSM
1 stop11h 53mMultiple Airlines
Deal found 12/11$377
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:00 pmDSM - LAX
1 stop7h 31mMultiple Airlines
Sun 1/43:30 pmLAX - DSM
2 stops26h 14mMultiple Airlines
Deal found 12/9$379
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:54 pmDSM - LAX
1 stop13h 24mMultiple Airlines
Mon 1/126:26 amLAX - DSM
1 stop10h 56mMultiple Airlines
Deal found 12/9$381
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:29 pmDSM - LAX
2 stops15h 44mFrontier
Sun 1/182:11 pmLAX - DSM
1 stop27h 12mFrontier
Deal found 12/11$385
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:06 pmDSM - LAX
1 stop7h 49mUnited Airlines
Sat 1/1712:30 amLAX - DSM
1 stop8h 25mUnited Airlines
Deal found 12/11$392

Find flight deals from Des Moines to Irvine

Keep the following information in mind while searching for Des Moines to Irvine flight deals. Data was last updated December 12, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$275
(American Airlines)

One-way from

$80
(Kiwi.com)

Popular in

March

Cheapest in

May

Average price

$434
Provider with most accurate pricing for Des Moines-Los Angeles flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Los Angeles flights.
Search Deals
From Des Moines to Irvine
Search Deals
One-way flight from Des Moines to Irvine
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($25 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Irvine that are best for you.

Fly from

Des Moines

Fly to

Irvine

Route

Depart

Return

Price

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Mon 1/26

8:30 am-3:12 pm

1 stop8h 42m

Los Angeles

Thu 1/29

8:20 am-9:21 pm

3 stops35h 01m

$288

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Fri 5/8

3:20 pm-5:45 pm

Nonstop4h 25m

Los Angeles

Tue 5/12

9:05 am-2:45 pm

Nonstop3h 40m

$294

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 1/21

12:25 pm-9:00 pm

1 stop10h 35m

Los Angeles

Sat 1/24

10:20 pm-9:41 am

1 stop9h 21m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 1/24

6:24 am-2:46 pm

1 stop10h 22m

Los Angeles

Sat 1/31

10:20 pm-9:41 am

1 stop9h 21m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 1/6

8:35 am-4:15 pm

2 stops9h 40m

Los Angeles

Sat 1/10

5:25 am-12:15 pm

1 stop4h 50m

$300

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 1/21

3:25 pm-5:26 pm

Nonstop4h 01m

Los Angeles

Sun 1/25

6:38 am-1:48 pm

1 stop5h 10m

$304

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 1/21

10:30 am-4:49 pm

1 stop8h 19m

Los Angeles

Sun 1/25

10:55 pm-10:41 am

1 stop9h 46m

$314

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 3/7

8:21 pm-12:17 am

1 stop5h 56m

$91

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Mon 3/9

8:21 pm-12:17 am

1 stop5h 56m

$91

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Fri 1/9

8:17 pm-8:28 pm

1 stop26h 11m

$104

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 17 results
1
2

Best time to book a flight from Des Moines to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Irvine

How far ahead should I book a flight from Des Moines to Irvine?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Irvine. Price data was last updated on December 5, 2025.

The price you pay for your flight from Des Moines to Irvine may vary depending on when you book. For the best chance of a lower fare, look to book 80 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Irvine?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $101). Flying from Des Moines to Irvine in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IR9?

Find hourly flight availability from Des Moines to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Irvine in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Des Moines to Irvine?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Irvine. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to Irvine flight should consider departing on Friday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Des Moines to Irvine

Explore weekly flight availability from Des Moines to Irvine. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 12, 2025.

The most flights from DSM to IR9 are scheduled on a Tuesday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing Irvine

Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Irvine. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
9,095 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,084 reviews
Southwest
7.9
Good
4,253 reviews

Food

7.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Irvine?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Irvine from Des Moines. Booking flights from Des Moines (DSM) to Irvine should be relatively easy as there is 1 daily outbound flight to Irvine from 6 different airlines.

  • How popular is this Des Moines to Irvine flight route?

    Flights from Des Moines to Irvine have been viewed 2 times in the past calendar month.

  • How long is the flight from Des Moines to Irvine?

    American Airlines and Delta can get you from Des Moines to Irvine in just under 4h 25m. Your travel time can differ by up to 6h 10m. Airlines will cover a distance of 1443 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Des Moines to Irvine one-way?

    To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $60. Frontier flights start at $73 while deals on Delta start at $110 one-way.

  • What are the cheapest flights from Des Moines to Irvine?

    While on average a flight from Des Moines to Irvine is generally $325, our data shows the cheapest flight currently is $122. When looking at the most popular route, (Des Moines - Los Angeles), you can expect to pay $217 for that flight.

  • Can I find deals for flights from Des Moines to Irvine that include hotel bookings?

    Yes. In addition to deals on Des Moines to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Irvine?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Irvine.

  • Can I find deals for business class flights from Des Moines to Irvine?

    Yes. Cheapflights offers flight deals from Des Moines to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Irvine?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $101). Flying from Des Moines to Irvine in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Des Moines to Irvine

Discover the top 6 airlines that operate flights from Des Moines to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$108Average$187FlexibilityNo cancel feeOn-time88%
FrontierCheapest$149Average$234FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$213Average$433FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$222Average$411FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$238Average$391FlexibilityNo cancel feeOn-time71%
DeltaCheapest$239Average$342FlexibilityNo cancel feeOn-timeN/A

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