HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$118+ Cheap flights from Spartanburg, SC to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
Apr 27 — May 41
Sun 4/27
Sun 5/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Spartanburg to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Spartanburg to Iowa

Keep the following information in mind while searching for Spartanburg to Iowa flight deals. Data was last updated April 22, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$204
(Mytrip)

One-way from

$118
(Mytrip)

Popular in

June

Cheapest in

March

Average price

$447
Provider with most accurate pricing for Charlotte Douglas-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Des Moines flights.
Search Deals
From Spartanburg to Iowa
Search Deals
One-way flight from Spartanburg to Iowa
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Spartanburg to Iowa

Cheapest flights from Spartanburg to Iowa
Explore the most affordable flight options available from Spartanburg to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:33 pmCLT - DSM
1 stop4h 51mMultiple Airlines
Sun 6/156:32 pmDSM - CLT
1 stop21h 05mMultiple Airlines
Deal found 4/22$204
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1212:45 pmCLT - OMA
1 stop4h 45mSouthwest
Tue 7/1510:50 amOMA - CLT
1 stop4h 15mSouthwest
Deal found 4/21$316
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/78:15 amCLT - SUX
1 stop7h 13mUnited Airlines
Sun 5/113:26 pmSUX - CLT
1 stop6h 19mUnited Airlines
Deal found 4/22$344
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/79:15 pmCLT - MLI
Nonstop2h 09mAmerican Airlines
Sun 6/85:02 amMLI - CLT
Nonstop2h 07mAmerican Airlines
Deal found 4/21$347
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/219:00 pmCLT - OMA
Nonstop2h 39mAmerican Airlines
Wed 5/282:39 pmOMA - CLT
Nonstop2h 36mAmerican Airlines
Deal found 4/21$357
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/77:00 amCLT - DSM
1 stop4h 14mDelta
Mon 9/82:14 pmDSM - CLT
1 stop7h 06mDelta
Deal found 4/22$363
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/102:52 pmCLT - DSM
Nonstop2h 23mAmerican Airlines
Sat 6/145:32 pmDSM - CLT
Nonstop2h 21mAmerican Airlines
Deal found 4/20$373
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/35:24 pmCLT - OMA
1 stop4h 32mDelta
Sun 9/75:35 amOMA - CLT
1 stop4h 31mDelta
Deal found 4/21$378
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/168:50 amCLT - CID
1 stop10h 18mMultiple Airlines
Sun 5/186:14 pmCID - CLT
2 stops19h 46mMultiple Airlines
Deal found 4/22$391
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/253:40 pmCLT - DSM
1 stop7h 30mSouthwest
Tue 4/295:40 amDSM - CLT
1 stop6h 40mSouthwest
Deal found 4/21$411
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/107:59 pmCLT - MLI
1 stop3h 58mDelta
Fri 5/236:00 amMLI - CLT
1 stop5h 34mDelta
Deal found 4/22$423
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2110:51 pmCLT - CID
1 stop15h 19mAmerican Airlines
Mon 5/262:00 pmCID - CLT
1 stop17h 07mAmerican Airlines
Deal found 4/21$423

Cheapflights Fare Finder

Customize your flight search to find flights from Spartanburg to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from Spartanburg to Iowa that are best for you.

Fly from

Spartanburg

Fly to

Iowa

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 6/13

5:33 pm-9:24 pm

1 stop4h 51m

Des Moines

Sun 6/15

6:32 pm-4:37 pm

1 stop21h 05m

$204

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Sat 7/12

12:45 pm-4:30 pm

1 stop4h 45m

Omaha Eppley Airfield

Tue 7/15

10:50 am-4:05 pm

1 stop4h 15m

$316

CharlotteSioux City

CLT - SUX

CLTSUX

Charlotte Douglas

Wed 5/7

8:15 am-2:28 pm

1 stop7h 13m

Sioux City Sioux Gateway

Sun 5/11

3:26 pm-10:45 pm

1 stop6h 19m

$344

CharlotteMoline

CLT - MLI

CLTMLI

Charlotte Douglas

Sat 6/7

9:15 pm-10:24 pm

Nonstop2h 09m

Moline Quad-City

Sun 6/8

5:02 am-8:09 am

Nonstop2h 07m

$347

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Wed 5/21

9:00 pm-10:39 pm

Nonstop2h 39m

Omaha Eppley Airfield

Wed 5/28

2:39 pm-6:15 pm

Nonstop2h 36m

$357

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 5/23

3:41 pm-9:06 pm

1 stop6h 25m

Des Moines

Sun 5/25

2:15 pm-8:16 pm

1 stop5h 01m

$363

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Tue 6/10

2:52 pm-4:15 pm

Nonstop2h 23m

Des Moines

Sat 6/14

5:32 pm-8:53 pm

Nonstop2h 21m

$373

CharlotteOmaha

CLT - OMA

CLTOMA

Charlotte Douglas

Wed 9/3

5:24 pm-8:56 pm

1 stop4h 32m

Omaha Eppley Airfield

Sun 9/7

5:35 am-11:06 am

1 stop4h 31m

$378

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

Fri 5/16

8:50 am-6:08 pm

1 stop10h 18m

Cedar Rapids

Sun 5/18

6:14 pm-3:00 pm

2 stops19h 46m

$391

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

Fri 4/25

3:40 pm-10:10 pm

1 stop7h 30m

Des Moines

Tue 4/29

5:40 am-1:20 pm

1 stop6h 40m

$411

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 42 results
1
2
3
...
5

Best time to book a flight from Spartanburg to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Iowa

What is the cheapest month to book a flight from Spartanburg to Iowa?

Currently, August is the cheapest month in which you can book a flight from Spartanburg to Iowa (average of $336). Flying from Spartanburg to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to IA?

Find hourly flight availability from Spartanburg to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

When flying from Spartanburg to Iowa, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Spartanburg to Iowa

Explore weekly flight availability from Spartanburg to Iowa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 22, 2025.

The most flights from SB1 to USIA are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in Iowa by month

Plan your trip to Iowa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Iowa ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Iowa when rainfall is around 1.0 in.

Temperature in Iowa by month

Plan your trip to Iowa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Iowa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated April 22, 2025.
To help decide which airline to fly from Spartanburg to Iowa, see what other customers have to say about Southwest, Delta and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,286 reviews

Food

7.1

Overall

8.0

Boarding

8.2

Entertainment

7.6

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,286 reviews
Southwest
8.0
Very good
4,286 reviews

Food

7.1

Overall

8.0

Boarding

8.2

Entertainment

7.6

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,920 reviews
Southwest
8.0
Very good
4,286 reviews

Food

7.1

Overall

8.0

Boarding

8.2

Entertainment

7.6

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,683 reviews
Southwest
8.0
Very good
4,286 reviews

Food

7.1

Overall

8.0

Boarding

8.2

Entertainment

7.6

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,286 reviews

Food

7.1

Overall

8.0

Boarding

8.2

Entertainment

7.6

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Frontier
6.0
Okay
3,283 reviews
Southwest
8.0
Very good
4,286 reviews

Food

7.1

Overall

8.0

Boarding

8.2

Entertainment

7.6

Comfort

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Spartanburg to Iowa one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $126. However, be on the lookout for offers from Southwest and Delta, as they are both options that can get you from Spartanburg to Iowa for a low price.

  • What are the most popular routes from Spartanburg to Iowa?

    When deciding which route to take from Spartanburg to Iowa consider Charlotte Douglas - Des Moines, Charlotte Douglas - Omaha Eppley Airfield or Charlotte Douglas - Cedar Rapids as they are the most popular.

  • What are the cheapest flights from Spartanburg to Iowa?

    On average you can expect to pay $315 for a flight from Spartanburg to Iowa. The cheapest flight overall is $121 while the most popular route, (Charlotte Douglas - Des Moines) is currently priced at $218.

  • Can I find deals for flights from Spartanburg to Iowa that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Iowa.

  • Can I find deals for business class flights from Spartanburg to Iowa?

    Yes. Cheapflights offers flight deals from Spartanburg to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Iowa?

    Currently, August is the cheapest month in which you can book a flight from Spartanburg to Iowa (average of $336). Flying from Spartanburg to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Spartanburg to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Charlotte to Newark flights
Charlotte to LaGuardia flights
Charlotte to Denver flights
Charlotte to Hobby flights
Charlotte to O'Hare Intl flights
Charlotte to Orlando flights
Charlotte to Seattle flights
Charlotte to Boston flights
Charlotte to Las Vegas flights
Charlotte to George Bush Intcntl flights
Charlotte to Fort Lauderdale flights
Charlotte to Miami flights
Charlotte to Dulles Intl flights
Charlotte to Dallas/Fort Worth flights
Charlotte to Salt Lake City flights
Charleston to O'Hare Intl flights
Charlotte to San Francisco flights
Charlotte to Detroit flights
Charleston to Seattle flights
Charleston to John F Kennedy Intl flights
Charlotte to Sky Harbor Intl flights
Charleston to Las Vegas flights
Savannah to Newark flights
Charlotte to Reagan-National flights
Charlotte to Honolulu flights
Savannah to John F Kennedy Intl flights
Charleston to Newark flights
Savannah to O'Hare Intl flights
Greenville to Denver flights
Charleston to Denver flights
Charlotte to San Diego flights
Charlotte to Minneapolis flights
Savannah to LaGuardia flights
Charleston to Fort Lauderdale flights
Charleston to LaGuardia flights
Charlotte to Atlanta flights
Greenville to Newark flights
Charlotte to Love Field flights
Charlotte to Los Angeles flights
Greenville to LaGuardia flights
Charlotte to New Orleans flights
Greenville to John F Kennedy Intl flights
Charlotte to Baltimore flights
Charlotte to Buffalo flights
Charlotte to Nashville flights
Charleston to Miami flights
Greenville to Seattle flights
Charleston to Boston flights
Charlotte to Midway flights

Top 3 airlines flying from Spartanburg to Iowa

Discover the top 3 airlines that operate flights from Spartanburg to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$155Average$345FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$216Average$458FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$223Average$432FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.