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$100+ Cheap flights from South Carolina to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
abr. 7 — abr. 141
lun. 4/7
lun. 4/14
1 adult, Economy
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Cheap flight deals from South Carolina to Iowa

Keep the following information in mind while searching for South Carolina to Iowa flight deals. Data was last updated abril 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$213
(Mytrip)

One-way from

$100
(Mytrip)

Popular in

January

Cheapest in

April

Average price

$258
Provider with most accurate pricing for Myrtle Beach Intl-Des Moines flight deals.
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From South Carolina to Iowa
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One-way flight from South Carolina to Iowa
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Highest demand for flights based on searches. 19% potential increase in price ($88 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from South Carolina to Iowa

Cheapest flights from South Carolina to Iowa
Explore the most affordable flight options available from South Carolina to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 2, 2025.

This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/89:02 pmCLT - CID
1 stop20h 55mMultiple Airlines
lun. 5/125:47 pmCID - CLT
1 stop27h 13mMultiple Airlines
Deal found 4/1$213
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/78:30 pmCHS - CID
1 stop4h 27mAmerican Airlines
mié. 6/117:15 amCID - CHS
1 stop6h 34mAmerican Airlines
Deal found 4/2$249
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/244:21 pmGSP - CID
1 stop7h 47mAmerican Airlines
mar. 5/271:36 pmCID - GSP
1 stop8h 07mAmerican Airlines
Deal found 4/1$254
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/2211:58 amCLT - DSM
1 stop25h 48mMultiple Airlines
lun. 5/265:25 pmDSM - CLT
2 stops27h 35mMultiple Airlines
Deal found 4/1$259
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/105:34 pmCLT - DSM
1 stop27h 19mFrontier
sáb. 6/148:38 pmDSM - CLT
1 stop18h 56mFrontier
Deal found 3/31$263
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/146:00 amGSP - OMA
1 stop6h 53mAmerican Airlines
mar. 5/209:34 amOMA - GSP
1 stop5h 01mAmerican Airlines
Deal found 4/1$271
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/235:46 amGSP - DSM
1 stop5h 55mDelta
mar. 4/294:45 pmDSM - GSP
1 stop4h 38mDelta
Deal found 4/1$271
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/226:08 pmCHS - OMA
1 stop5h 15mAmerican Airlines
mar. 4/296:25 amOMA - CHS
1 stop6h 41mAmerican Airlines
Deal found 4/1$285
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/76:00 amGSP - DSM
2 stops9h 38mUnited Airlines
sáb. 5/103:20 pmDSM - GSP
1 stop5h 55mUnited Airlines
Deal found 4/1$289
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/78:56 pmCLT - MLI
Nonstop2h 18mAmerican Airlines
sáb. 5/174:25 pmMLI - CLT
Nonstop2h 09mAmerican Airlines
Deal found 4/1$301
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/35:28 amGSP - DSM
2 stops7h 27mAmerican Airlines
sáb. 5/106:45 amDSM - GSP
1 stop4h 44mAmerican Airlines
Deal found 4/1$302
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/145:40 amCLT - DSM
1 stop6h 01mDelta
mié. 5/215:35 amDSM - CLT
1 stop5h 59mDelta
Deal found 3/31$307

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2025.
Use the filters below to find and compare flights from South Carolina to Iowa that are best for you.

Fly from

South Carolina

Fly to

Iowa

Route

Depart

Return

Price

CharlotteCedar Rapids

CLT - CID

CLTCID

Charlotte Douglas

jue. 5/8

9:02 pm-4:57 pm

1 stop20h 55m

Cedar Rapids

lun. 5/12

5:47 pm-10:00 pm

1 stop27h 13m

$213

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

sáb. 6/7

8:30 pm-11:57 pm

1 stop4h 27m

Cedar Rapids

mié. 6/11

7:15 am-2:49 pm

1 stop6h 34m

$249

GreenvilleCedar Rapids

GSP - CID

GSPCID

Greenville

sáb. 5/24

4:21 pm-11:08 pm

1 stop7h 47m

Cedar Rapids

mar. 5/27

1:36 pm-10:43 pm

1 stop8h 07m

$254

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

jue. 5/22

11:58 am-12:46 pm

1 stop25h 48m

Des Moines

lun. 5/26

5:25 pm-10:00 pm

2 stops27h 35m

$259

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mar. 6/10

5:34 pm-7:53 pm

1 stop27h 19m

Des Moines

sáb. 6/14

8:38 pm-4:34 pm

1 stop18h 56m

$263

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

mié. 4/23

5:46 am-10:41 am

1 stop5h 55m

Des Moines

mar. 4/29

2:15 pm-9:45 pm

1 stop6h 30m

$271

GreenvilleOmaha

GSP - OMA

GSPOMA

Greenville

mié. 5/14

6:00 am-11:53 am

1 stop6h 53m

Omaha Eppley Airfield

mar. 5/20

9:34 am-3:35 pm

1 stop5h 01m

$271

CharlestonOmaha

CHS - OMA

CHSOMA

Charleston

mar. 4/22

6:08 pm-10:23 pm

1 stop5h 15m

Omaha Eppley Airfield

mar. 4/29

6:25 am-2:06 pm

1 stop6h 41m

$285

GreenvilleDes Moines

GSP - DSM

GSPDSM

Greenville

mié. 5/7

6:00 am-2:38 pm

2 stops9h 38m

Des Moines

sáb. 5/10

3:20 pm-10:15 pm

1 stop5h 55m

$289

CharlotteMoline

CLT - MLI

CLTMLI

Charlotte Douglas

mié. 5/7

8:56 pm-10:14 pm

Nonstop2h 18m

Moline Quad-City

sáb. 5/17

4:25 pm-7:34 pm

Nonstop2h 09m

$301

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 59 results
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Best time to book a flight from South Carolina to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Iowa

What is the cheapest month to book a flight from South Carolina to Iowa?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $336). Flying from South Carolina to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IA?

Find hourly flight availability from South Carolina to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Iowa as you normally would.

Rainfall in Iowa by month

Plan your trip to Iowa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Iowa ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Iowa when rainfall is around 1.0 in.

Temperature in Iowa by month

Plan your trip to Iowa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Iowa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated abril 2, 2025.
Read through reviews of airlines operating flights from South Carolina to Iowa, such as Southwest, Delta and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,275 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,897 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,616 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Allegiant Air
7.3
Good
731 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,275 reviews

Food

7.1

Entertainment

7.6

Overall

8.0

Boarding

8.2

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Iowa one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $110. American Airlines flights start at $136 while deals on Delta start at $152 one-way.

  • Can I find deals for flights from South Carolina to Iowa that include hotel bookings?

    Yes. In addition to deals on South Carolina to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Iowa.

  • Can I find deals for business class flights from South Carolina to Iowa?

    Yes. Cheapflights offers flight deals from South Carolina to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Iowa?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Iowa (average of $336). Flying from South Carolina to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Iowa

Discover the top 3 airlines that operate flights from South Carolina to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$188Average$405FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$386FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$418FlexibilityNo cancel feeOn-time69%

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