HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$49+ Cheap flights from Missouri to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Iowa

Keep the following information in mind while searching for Missouri to Iowa flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$180
(Southwest)

One-way from

$49
(Southwest)

Good round-trip deal

$145 or less

Good one-way deal

$102 or less
Provider with most accurate pricing for Kansas City-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Kansas City-Des Moines flights.
Search Deals
From Missouri to Iowa
Search Deals
One-way flight from Missouri to Iowa
Search Deals
Price to beat on a round-trip flight from Missouri to Iowa.
Search Deals
Price to beat on a one-way flight from Missouri to Iowa.
Search Deals

Find flight deals from Missouri to Iowa

Cheapest flights from Missouri to Iowa
Explore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/99:55 pmSTL - DSM
Nonstop1h 10mSouthwest
Mon 5/125:30 pmDSM - STL
Nonstop1h 05mSouthwest
Deal found 4/16$180
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/91:09 pmSTL - DSM
1 stop4h 41mDelta
Mon 5/126:35 pmDSM - STL
1 stop5h 03mDelta
Deal found 4/16$225
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/13:20 pmSGF - MLI
1 stop6h 15mUnited Airlines
Mon 5/53:56 pmMLI - SGF
1 stop6h 05mUnited Airlines
Deal found 4/16$239
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/89:55 pmSTL - OMA
Nonstop1h 15mSouthwest
Tue 5/134:40 pmOMA - STL
Nonstop1h 15mSouthwest
Deal found 4/16$256
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1811:38 amMCI - MLI
1 stop5h 09mUnited Airlines
Mon 4/213:50 pmMLI - MCI
1 stop6h 10mUnited Airlines
Deal found 4/17$259
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:10 pmSTL - DSM
1 stop27h 48mMultiple Airlines
Mon 5/52:28 pmDSM - STL
1 stop26h 47mMultiple Airlines
Deal found 4/16$265
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/86:00 amSTL - OMA
1 stop4h 06mAmerican Airlines
Sun 5/115:00 amOMA - STL
1 stop4h 49mAmerican Airlines
Deal found 4/17$273
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/128:03 pmMCI - OMA
1 stop23h 02mMultiple Airlines
Mon 6/1611:36 amOMA - MCI
1 stop7h 19mMultiple Airlines
Deal found 4/17$369
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/95:25 amMCI - OMA
1 stop4h 05mSouthwest
Fri 5/165:25 pmOMA - MCI
1 stop5h 10mSouthwest
Deal found 4/16$375
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/95:46 pmMCI - OMA
1 stop25h 05mAmerican Airlines
Sun 5/115:00 amOMA - MCI
1 stop11h 45mAmerican Airlines
Deal found 4/16$403
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/166:00 amSTL - DSM
1 stop5h 13mAmerican Airlines
Sun 5/185:32 amDSM - STL
1 stop4h 17mAmerican Airlines
Deal found 4/17$414
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:10 pmSTL - OMA
2 stops16h 38mMultiple Airlines
Sun 5/411:16 amOMA - STL
3 stops31h 25mMultiple Airlines
Deal found 4/16$463

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Missouri to Iowa that are best for you.

Fly from

Missouri

Fly to

Iowa

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 5/9

9:55 pm-11:05 pm

Nonstop1h 10m

Des Moines

Mon 5/12

5:30 pm-6:35 pm

Nonstop1h 05m

$180

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Fri 5/9

1:09 pm-5:50 pm

1 stop4h 41m

Des Moines

Mon 5/12

6:35 pm-11:38 pm

1 stop5h 03m

$225

SpringfieldMoline

SGF - MLI

SGFMLI

Springfield-Branson

Thu 5/1

3:20 pm-9:35 pm

1 stop6h 15m

Moline Quad-City

Mon 5/5

3:56 pm-10:01 pm

1 stop6h 05m

$239

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Thu 5/8

9:55 pm-11:10 pm

Nonstop1h 15m

Omaha Eppley Airfield

Tue 5/13

4:40 pm-5:55 pm

Nonstop1h 15m

$256

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 5/1

6:10 pm-9:58 pm

1 stop27h 48m

Des Moines

Mon 5/5

2:28 pm-5:15 pm

1 stop26h 47m

$265

St. LouisOmaha

STL - OMA

STLOMA

Lambert-St Louis

Thu 5/8

6:00 am-10:06 am

1 stop4h 06m

Omaha Eppley Airfield

Sun 5/11

5:00 am-9:49 am

1 stop4h 49m

$273

Kansas CityOmaha

MCI - OMA

MCIOMA

Kansas City

Thu 6/12

8:03 pm-7:05 pm

1 stop23h 02m

Omaha Eppley Airfield

Mon 6/16

11:36 am-6:55 pm

1 stop7h 19m

$369

Kansas CityOmaha

MCI - OMA

MCIOMA

Kansas City

Fri 5/9

5:25 am-9:30 am

1 stop4h 05m

Omaha Eppley Airfield

Fri 5/16

5:25 pm-10:35 pm

1 stop5h 10m

$375

Kansas CityOmaha

MCI - OMA

MCIOMA

Kansas City

Fri 5/9

5:46 pm-6:51 pm

1 stop25h 05m

Omaha Eppley Airfield

Sun 5/11

5:00 am-4:45 pm

1 stop11h 45m

$403

Kansas CityMoline

MCI - MLI

MCIMLI

Kansas City

Fri 5/2

6:40 pm-10:11 am

1 stop15h 31m

Moline Quad-City

Tue 5/6

5:25 pm-9:47 pm

1 stop4h 22m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 38 results
1
2
3
4

Best time to book a flight from Missouri to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Iowa

What is the cheapest month to book a flight from Missouri to Iowa?

Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IA?

Find hourly flight availability from Missouri to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Iowa as you normally would.

Rainfall in Iowa by month

Plan your trip to Iowa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Iowa ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Iowa when rainfall is around 1.0 in.

Temperature in Iowa by month

Plan your trip to Iowa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Iowa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated April 17, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Missouri to Iowa to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,882 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.5

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,882 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.5

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Southwest
8.0
Very good
4,280 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.5

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,917 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.5

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,667 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.5

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Allegiant Air
7.3
Good
734 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.5

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Missouri to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to Iowa flight route?

    The Missouri to Iowa flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Missouri to Iowa one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from American Airlines and Frontier, as they are both options that can get you from Missouri to Iowa for a low price.

  • Can I find deals for flights from Missouri to Iowa that include hotel bookings?

    Yes. In addition to deals on Missouri to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Iowa.

  • Can I find deals for business class flights from Missouri to Iowa?

    Yes. Cheapflights offers flight deals from Missouri to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Iowa?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Iowa (average of $336). Flying from Missouri to Iowa in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Fort Lauderdale flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to Los Angeles flights
Newark to Orlando flights
John F Kennedy Intl to Miami flights
Newark to Los Angeles flights
LaGuardia to Miami flights
Newark to Miami flights
San Francisco to John F Kennedy Intl flights
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Dallas/Fort Worth flights
John F Kennedy Intl to Fort Lauderdale flights
Dallas/Fort Worth to LaGuardia flights
Dallas/Fort Worth to John F Kennedy Intl flights
Dallas/Fort Worth to Seattle flights
John F Kennedy Intl to Las Vegas flights
O'Hare Intl to Las Vegas flights
Newark to Las Vegas flights
John F Kennedy Intl to San Francisco flights
LaGuardia to Orlando flights
John F Kennedy Intl to O'Hare Intl flights
Los Angeles to Newark flights
LaGuardia to Dallas/Fort Worth flights
LaGuardia to O'Hare Intl flights
John F Kennedy Intl to Orlando flights
LaGuardia to Atlanta flights
Los Angeles to Boston flights
Dallas/Fort Worth to O'Hare Intl flights
Los Angeles to Honolulu flights
Newark to O'Hare Intl flights
Newark to Seattle flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to LaGuardia flights
Dallas/Fort Worth to Las Vegas flights
San Francisco to Newark flights
John F Kennedy Intl to Seattle flights
Newark to Tampa flights
Dallas/Fort Worth to Newark flights
O'Hare Intl to John F Kennedy Intl flights
Los Angeles to Seattle flights
John F Kennedy Intl to West Palm Beach flights
Newark to Dallas/Fort Worth flights
Seattle to Newark flights
Seattle to Los Angeles flights
Los Angeles to LaGuardia flights
LaGuardia to Los Angeles flights
Newark to San Francisco flights
Seattle to Las Vegas flights
Fort Lauderdale to Newark flights
LaGuardia to Hobby flights

Top 3 airlines flying from Missouri to Iowa

Discover the top 3 airlines that operate flights from Missouri to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Southern / MokuleleCheapest$51Average$78FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$167Average$310FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$208Average$403FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.