HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indianapolis

$49+ Cheap flights from South Carolina to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Indianapolis with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Indianapolis

Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$93
(Cheapflightsfares)

One-way from

$49
(Cheapflightsfares)

Popular in

March

Cheapest in

May

Average price

$443

Good one-way deal

$102 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From South Carolina to Indianapolis
Search Deals
One-way flight from South Carolina to Indianapolis
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($91 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals
Price to beat on a one-way flight from South Carolina to Indianapolis.
Search Deals

Find flight deals from South Carolina to Indianapolis

Cheapest flights from South Carolina to Indianapolis
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/72:05 pmSAV - IND
Nonstop1h 51mAllegiant Air
Mon 3/104:46 pmIND - SAV
Nonstop1h 48mAllegiant Air
Deal found 2/19$93
This Priceline deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/311:45 amCLT - IND
1 stop6h 18mSpirit Airlines
Wed 4/92:36 pmIND - CLT
1 stop5h 04mSpirit Airlines
Deal found 2/19$106
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/72:59 pmCHS - IND
1 stop27h 04mSpirit Airlines
Tue 3/117:02 pmIND - CHS
1 stop19h 02mSpirit Airlines
Deal found 2/20$110
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/18:41 amCLT - IND
1 stop5h 00mMultiple Airlines
Sun 5/49:18 amIND - CLT
1 stop7h 13mMultiple Airlines
Deal found 2/19$119
This Cheapflightsfares deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/306:00 amMYR - IND
1 stop6h 59mSpirit Airlines
Sat 5/1010:51 amIND - MYR
1 stop6h 46mSpirit Airlines
Deal found 2/20$152
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/72:05 pmSAV - IND
Nonstop1h 51mMultiple Airlines
Mon 3/1010:23 amIND - SAV
1 stop12h 51mMultiple Airlines
Deal found 2/19$155
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/165:55 pmCLT - IND
1 stop6h 33mDelta
Mon 4/218:10 amIND - CLT
1 stop6h 44mDelta
Deal found 2/19$167
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/271:03 pmCHS - IND
1 stop6h 32mMultiple Airlines
Thu 3/62:38 pmIND - CHS
1 stop19h 15mMultiple Airlines
Deal found 2/20$175
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/278:08 amCLT - IND
1 stop7h 12mFrontier
Sun 3/304:20 pmIND - CLT
1 stop14h 48mFrontier
Deal found 2/20$208
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/85:40 amCAE - IND
1 stop3h 15mDelta
Sun 4/137:58 pmIND - CAE
1 stop3h 41mDelta
Deal found 2/20$229
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/125:47 amGSP - IND
1 stop4h 57mDelta
Wed 3/196:00 amIND - GSP
1 stop3h 27mDelta
Deal found 2/20$247
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1212:35 pmGSP - IND
2 stops7h 10mSouthwest
Wed 3/196:05 amIND - GSP
1 stop4h 45mSouthwest
Deal found 2/20$252

Find flights from South Carolina to Indianapolis within your budget

Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

South Carolina

Fly to

Indianapolis

Route

Depart

Return

Price

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Fri 3/7

2:05 pm-3:56 pm

Nonstop1h 51m

Indianapolis

Mon 3/10

4:46 pm-6:34 pm

Nonstop1h 48m

$93

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 4/3

11:45 am-6:03 pm

1 stop6h 18m

Indianapolis

Wed 4/9

2:36 pm-7:40 pm

1 stop5h 04m

$106

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Fri 3/7

2:59 pm-6:03 pm

1 stop27h 04m

Indianapolis

Tue 3/11

7:02 pm-2:04 pm

1 stop19h 02m

$110

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 5/1

8:41 am-1:41 pm

1 stop5h 00m

Indianapolis

Sun 5/4

9:18 am-4:31 pm

1 stop7h 13m

$119

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Wed 4/30

6:00 am-12:59 pm

1 stop6h 59m

Indianapolis

Sat 5/10

10:51 am-5:37 pm

1 stop6h 46m

$152

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Fri 3/7

2:05 pm-3:56 pm

Nonstop1h 51m

Indianapolis

Mon 3/10

10:23 am-11:14 pm

1 stop12h 51m

$155

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Wed 4/16

5:55 pm-12:28 am

1 stop6h 33m

Indianapolis

Mon 4/21

8:10 am-2:54 pm

1 stop6h 44m

$167

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Tue 3/4

1:03 pm-7:35 pm

1 stop6h 32m

Indianapolis

Thu 3/6

2:38 pm-5:01 pm

3 stops26h 23m

$181

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 3/27

8:08 am-3:20 pm

1 stop7h 12m

Indianapolis

Sun 3/30

4:20 pm-7:08 am

1 stop14h 48m

$208

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Tue 4/8

5:40 am-8:55 am

1 stop3h 15m

Indianapolis

Sun 4/13

7:58 pm-11:39 pm

1 stop3h 41m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 57 results
1
2
3
...
6

Best time to book a flight from South Carolina to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Indianapolis

Get recent, data-driven insights about flights from South Carolina to Indianapolis including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IND?

Find hourly flight availability from South Carolina to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Indianapolis as you normally would.

Rainfall in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

Temperature in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated February 20, 2025.
Read through reviews of airlines operating flights from South Carolina to Indianapolis, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Overall

8.1

Food

7.1

Crew

8.7

Boarding

8.2

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from South Carolina?

    Indianapolis (IND) is the airport you will fly into if you book a flight from South Carolina to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How popular is this South Carolina to Indianapolis flight route?

    The South Carolina to Indianapolis flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from South Carolina to Indianapolis one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from Allegiant Air and Frontier, as they are both options that can get you from South Carolina to Indianapolis for a low price.

  • What are the most popular routes from South Carolina to Indianapolis?

    When deciding which route to take from South Carolina to Indianapolis consider Charlotte Douglas - Indianapolis, Greenville - Indianapolis or Myrtle Beach Intl - Indianapolis as they are the most popular.

  • Can I find deals for flights from South Carolina to Indianapolis that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indianapolis.

  • Can I find deals for business class flights from South Carolina to Indianapolis?

    Yes. Cheapflights offers flight deals from South Carolina to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Greenwood
Bloomington
Terre Haute
Noblesville
Fishers
Anderson
Carmel
Franklin
Plainfield
Crawfordsville
Kokomo
Muncie
Shelbyville
Speedway

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to O'Hare Intl flights
Dallas/Fort Worth to O'Hare Intl flights
Los Angeles to O'Hare Intl flights
Newark to O'Hare Intl flights
LaGuardia to O'Hare Intl flights
Dulles Intl to O'Hare Intl flights
Boston to O'Hare Intl flights
Seattle to O'Hare Intl flights
Baltimore to O'Hare Intl flights
San Francisco to O'Hare Intl flights
Reagan-National to O'Hare Intl flights
Newark to Midway flights
John F Kennedy Intl to Midway flights
Philadelphia to O'Hare Intl flights
Denver to O'Hare Intl flights
Sky Harbor Intl to O'Hare Intl flights
Minneapolis to O'Hare Intl flights
Dallas/Fort Worth to Midway flights
LaGuardia to Midway flights
Los Angeles to Midway flights
Baltimore to Midway flights
Austin to O'Hare Intl flights
Fort Lauderdale to O'Hare Intl flights
Ontario to O'Hare Intl flights
Santa Ana to O'Hare Intl flights
Atlanta to O'Hare Intl flights
Reagan-National to Midway flights
Raleigh to O'Hare Intl flights
Burbank to O'Hare Intl flights
San Diego to O'Hare Intl flights
John F Kennedy Intl to Indianapolis flights
Dulles Intl to Midway flights
Charlotte to O'Hare Intl flights
San Francisco to Midway flights
LaGuardia to Indianapolis flights
Orlando to O'Hare Intl flights
Love Field to O'Hare Intl flights
Miami to O'Hare Intl flights
Seattle to Midway flights
Atlanta to Midway flights
Newark to Indianapolis flights
Portland to O'Hare Intl flights
George Bush Intcntl to O'Hare Intl flights
Minneapolis to Midway flights
Philadelphia to Midway flights
Tampa to O'Hare Intl flights
LaGuardia to Cincinnati flights
Cleveland to O'Hare Intl flights
Hobby to O'Hare Intl flights
John F Kennedy Intl to Cincinnati flights

Top 6 airlines flying from South Carolina to Indianapolis

Discover the top 6 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$67Average$140FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$108Average$228FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$194Average$387FlexibilityNo cancel feeOn-time71%
DeltaCheapest$197Average$349FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$228Average$469FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$286Average$392FlexibilityNo cancel feeOn-time63%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.