HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indianapolis

$44+ Cheap flights from South Carolina to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Indianapolis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Indianapolis

Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$98
(Mytrip)

One-way from

$44
(Booking.com)

Popular in

March

Cheapest in

August

Average price

$477
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From South Carolina to Indianapolis
Search Deals
One-way flight from South Carolina to Indianapolis
Search Deals
Highest demand for flights based on searches. 34% potential increase in price ($194 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from South Carolina to Indianapolis

Cheapest flights from South Carolina to Indianapolis
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/910:00 amSAV - IND
Nonstop1h 54mAllegiant Air
Mon 5/1212:44 pmIND - SAV
Nonstop1h 48mAllegiant Air
Deal found 4/23$98
This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/85:32 pmMYR - IND
1 stop5h 43mSpirit Airlines
Mon 5/125:45 amIND - MYR
1 stop5h 14mSpirit Airlines
Deal found 4/23$148
This Frontier deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:36 pmCLT - IND
1 stop11h 05mFrontier
Sun 5/189:18 amIND - CLT
1 stop7h 21mFrontier
Deal found 4/23$160
This Cheapflightsfares deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:38 pmCLT - IND
Nonstop1h 41mSpirit Airlines
Sun 5/189:14 pmIND - CLT
Nonstop1h 45mSpirit Airlines
Deal found 4/23$168
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/910:00 amSAV - IND
Nonstop1h 54mMultiple Airlines
Mon 5/128:15 amIND - SAV
1 stop14h 58mMultiple Airlines
Deal found 4/23$175
This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1110:36 pmCLT - IND
1 stop11h 15mMultiple Airlines
Thu 5/159:14 pmIND - CLT
Nonstop1h 45mMultiple Airlines
Deal found 4/23$186
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/236:40 pmCHS - IND
Nonstop1h 52mMultiple Airlines
Sun 5/255:31 pmIND - CHS
2 stops18h 02mMultiple Airlines
Deal found 4/22$201
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/75:59 pmAGS - IND
1 stop5h 03mDelta
Tue 6/104:50 pmIND - AGS
1 stop4h 37mDelta
Deal found 4/24$227
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/56:05 amCAE - IND
1 stop5h 09mDelta
Tue 6/108:25 amIND - CAE
1 stop4h 33mDelta
Deal found 4/23$229
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:25 amCAE - IND
1 stop4h 48mAmerican Airlines
Tue 5/131:07 pmIND - CAE
1 stop4h 31mAmerican Airlines
Deal found 4/22$234
This Cheapflightsfares deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:00 amCHS - IND
1 stop5h 10mSpirit Airlines
Thu 5/2912:05 pmIND - CHS
1 stop10h 04mSpirit Airlines
Deal found 4/23$248
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/208:36 pmCLT - IND
Nonstop1h 38mAmerican Airlines
Tue 5/276:10 amIND - CLT
Nonstop1h 43mAmerican Airlines
Deal found 4/23$248

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.

Fly from

South Carolina

Fly to

Indianapolis

Route

Depart

Return

Price

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Fri 5/9

10:00 am-11:54 am

Nonstop1h 54m

Indianapolis

Mon 5/12

12:44 pm-2:32 pm

Nonstop1h 48m

$98

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 5/8

5:32 pm-11:15 pm

1 stop5h 43m

Indianapolis

Mon 5/12

5:45 am-10:59 am

1 stop5h 14m

$148

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 5/15

10:36 pm-9:41 am

1 stop11h 05m

Indianapolis

Sun 5/18

9:18 am-4:39 pm

1 stop7h 21m

$160

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 5/15

6:38 pm-8:19 pm

Nonstop1h 41m

Indianapolis

Sun 5/18

9:18 am-4:39 pm

1 stop7h 21m

$168

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Fri 5/9

10:00 am-11:54 am

Nonstop1h 54m

Indianapolis

Mon 5/12

8:15 am-11:13 pm

1 stop14h 58m

$175

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Sun 5/11

6:38 pm-8:19 pm

Nonstop1h 41m

Indianapolis

Thu 5/15

9:14 pm-10:59 pm

Nonstop1h 45m

$190

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Fri 5/23

6:40 pm-8:32 pm

Nonstop1h 52m

Indianapolis

Sun 5/25

5:31 pm-11:33 am

2 stops18h 02m

$201

AugustaIndianapolis

AGS - IND

AGSIND

Augusta Bush Field

Sat 6/7

5:59 pm-11:02 pm

1 stop5h 03m

Indianapolis

Tue 6/10

4:50 pm-9:27 pm

1 stop4h 37m

$227

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Thu 6/5

6:05 am-11:14 am

1 stop5h 09m

Indianapolis

Tue 6/10

8:25 am-12:58 pm

1 stop4h 33m

$229

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Thu 5/8

7:25 am-12:13 pm

1 stop4h 48m

Indianapolis

Tue 5/13

1:07 pm-5:38 pm

1 stop4h 31m

$234

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 55 results
1
2
3
...
6

Best time to book a flight from South Carolina to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indianapolis

What is the cheapest month to book a flight from South Carolina to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IND?

Find hourly flight availability from South Carolina to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Indianapolis as you normally would.

Rainfall in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

Temperature in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated April 24, 2025.
Read through reviews of airlines operating flights from South Carolina to Indianapolis, such as Alaska Airlines, Southwest and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,918 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.1

Boarding

8.2

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,918 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.1

Boarding

8.2

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.1

Boarding

8.2

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,920 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.1

Boarding

8.2

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,685 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.1

Boarding

8.2

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Allegiant Air
7.3
Good
734 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.1

Boarding

8.2

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from South Carolina?

    Indianapolis (IND) is the airport you will fly into if you book a flight from South Carolina to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How popular is this South Carolina to Indianapolis flight route?

    The South Carolina to Indianapolis flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from South Carolina to Indianapolis one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $44. However, be on the lookout for offers from Spirit Airlines and Frontier, as they are both options that can get you from South Carolina to Indianapolis for a low price.

  • What are the most popular routes from South Carolina to Indianapolis?

    When deciding which route to take from South Carolina to Indianapolis consider Charlotte Douglas - Indianapolis, Augusta Bush Field - Indianapolis or Charleston - Indianapolis as they are the most popular.

  • Can I find deals for flights from South Carolina to Indianapolis that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indianapolis.

  • Can I find deals for business class flights from South Carolina to Indianapolis?

    Yes. Cheapflights offers flight deals from South Carolina to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Greenwood
Bloomington
Terre Haute
Noblesville
Muncie
Fishers
Carmel
Anderson
Kokomo
Franklin
Plainfield
Crawfordsville
Shelbyville
Speedway

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to O'Hare Intl flights
LaGuardia to O'Hare Intl flights
Dallas/Fort Worth to O'Hare Intl flights
Newark to O'Hare Intl flights
Los Angeles to O'Hare Intl flights
Newark to Midway flights
San Francisco to O'Hare Intl flights
John F Kennedy Intl to Midway flights
Boston to O'Hare Intl flights
Dallas/Fort Worth to Midway flights
Philadelphia to O'Hare Intl flights
Seattle to O'Hare Intl flights
Reagan-National to O'Hare Intl flights
Dulles Intl to O'Hare Intl flights
Denver to O'Hare Intl flights
Ontario to O'Hare Intl flights
San Francisco to Midway flights
Baltimore to O'Hare Intl flights
Raleigh to O'Hare Intl flights
Sky Harbor Intl to O'Hare Intl flights
Santa Ana to O'Hare Intl flights
LaGuardia to Midway flights
Dulles Intl to Midway flights
John F Kennedy Intl to Indianapolis flights
Atlanta to O'Hare Intl flights
John F Kennedy Intl to Cincinnati flights
Hobby to O'Hare Intl flights
San Diego to O'Hare Intl flights
Atlanta to Midway flights
Portland to O'Hare Intl flights
Burbank to O'Hare Intl flights
George Bush Intcntl to O'Hare Intl flights
Orlando to O'Hare Intl flights
Austin to O'Hare Intl flights
Charlotte to O'Hare Intl flights
Newark to Cincinnati flights
Newark to Indianapolis flights
Fort Lauderdale to O'Hare Intl flights
Hartford to O'Hare Intl flights
LaGuardia to Indianapolis flights
Minneapolis to O'Hare Intl flights
Miami to O'Hare Intl flights
Reagan-National to Midway flights
Oakland to O'Hare Intl flights
San Jose to O'Hare Intl flights
Los Angeles to Midway flights
LaGuardia to Cincinnati flights
Tampa to O'Hare Intl flights
Dallas/Fort Worth to Cincinnati flights
Philadelphia to Midway flights

Top 6 airlines flying from South Carolina to Indianapolis

Discover the top 6 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$67Average$144FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$115Average$236FlexibilityNo cancel feeOn-time65%
DeltaCheapest$218Average$349FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$228Average$428FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$377FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$286Average$402FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.