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$45+ Cheap flights from South Carolina to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from South Carolina to Indianapolis

Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$103
(Gotogate)

One-way from

$45
(Booking.com)

Popular in

March

Cheapest in

August

Average price

$709
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
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From South Carolina to Indianapolis
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One-way flight from South Carolina to Indianapolis
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Highest demand for flights based on searches. 32% potential increase in price ($170 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from South Carolina to Indianapolis

Cheapest flights from South Carolina to Indianapolis
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This Gotogate deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/910:00 amSAV - IND
Nonstop1h 54mAllegiant Air
Sat 5/171:34 pmIND - SAV
Nonstop1h 48mAllegiant Air
Deal found 3/30$103
This Cheapflightsfares deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:38 pmCLT - IND
Nonstop1h 41mSpirit Airlines
Sun 5/189:14 pmIND - CLT
Nonstop1h 45mSpirit Airlines
Deal found 3/30$127
This Priceline deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:00 amCHS - IND
1 stop5h 10mSpirit Airlines
Sat 5/1712:05 pmIND - CHS
1 stop10h 04mSpirit Airlines
Deal found 3/30$144
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/912:34 pmSAV - IND
1 stop10h 41mMultiple Airlines
Sat 5/171:34 pmIND - SAV
Nonstop1h 48mMultiple Airlines
Deal found 3/30$145
This FlightHub deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:38 pmCLT - IND
Nonstop1h 41mMultiple Airlines
Sun 5/189:18 amIND - CLT
1 stop7h 21mMultiple Airlines
Deal found 3/30$149
This Booking.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/306:40 pmCHS - IND
Nonstop1h 52mAllegiant Air
Mon 6/23:58 pmIND - CHS
Nonstop1h 57mAllegiant Air
Deal found 3/30$157
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/810:36 pmCLT - IND
1 stop11h 05mFrontier
Sun 5/119:18 amIND - CLT
1 stop7h 21mFrontier
Deal found 3/31$158
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/110:25 amCHS - IND
1 stop10h 41mMultiple Airlines
Mon 5/52:36 pmIND - CHS
1 stop17h 34mMultiple Airlines
Deal found 3/30$169
This Cheapflightsfares deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2812:08 pmMYR - IND
1 stop5h 36mSpirit Airlines
Tue 4/295:35 amIND - MYR
1 stop7h 29mSpirit Airlines
Deal found 3/31$171
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/76:00 amSAV - IND
1 stop5h 14mDelta
Wed 5/146:00 amIND - SAV
1 stop3h 16mDelta
Deal found 3/30$201
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/305:05 pmCAE - IND
1 stop5h 19mDelta
Mon 6/96:00 amIND - CAE
1 stop4h 14mDelta
Deal found 3/29$214
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/75:59 pmAGS - IND
1 stop6h 16mDelta
Tue 6/101:44 pmIND - AGS
1 stop5h 30mDelta
Deal found 3/30$227

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.

Fly from

South Carolina

Fly to

Indianapolis

Route

Depart

Return

Price

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Fri 5/9

10:00 am-11:54 am

Nonstop1h 54m

Indianapolis

Sat 5/17

1:34 pm-3:22 pm

Nonstop1h 48m

$103

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 5/15

6:38 pm-8:19 pm

Nonstop1h 41m

Indianapolis

Sun 5/18

9:14 pm-10:59 pm

Nonstop1h 45m

$127

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Tue 5/13

6:00 am-11:10 am

1 stop5h 10m

Indianapolis

Sat 5/17

12:05 pm-10:09 pm

1 stop10h 04m

$144

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Fri 5/9

12:34 pm-11:15 pm

1 stop10h 41m

Indianapolis

Sat 5/17

1:34 pm-3:22 pm

Nonstop1h 48m

$145

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 5/15

6:38 pm-8:19 pm

Nonstop1h 41m

Indianapolis

Sun 5/18

9:18 am-4:39 pm

1 stop7h 21m

$149

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Fri 5/30

6:40 pm-8:32 pm

Nonstop1h 52m

Indianapolis

Mon 6/2

3:58 pm-5:55 pm

Nonstop1h 57m

$157

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 5/8

10:36 pm-9:41 am

1 stop11h 05m

Indianapolis

Sun 5/11

9:18 am-4:39 pm

1 stop7h 21m

$158

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Thu 5/1

10:25 am-9:06 pm

1 stop10h 41m

Indianapolis

Mon 5/5

2:36 pm-8:10 am

1 stop17h 34m

$169

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Mon 4/28

12:08 pm-5:44 pm

1 stop5h 36m

Indianapolis

Tue 4/29

5:35 am-1:04 pm

1 stop7h 29m

$171

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

Wed 5/7

6:00 am-11:14 am

1 stop5h 14m

Indianapolis

Wed 5/14

6:00 am-9:16 am

1 stop3h 16m

$201

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 54 results
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Best time to book a flight from South Carolina to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indianapolis

What is the cheapest month to book a flight from South Carolina to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IND?

Find hourly flight availability from South Carolina to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Indianapolis as you normally would.

Rainfall in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

Temperature in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated March 31, 2025.
Read through reviews of airlines operating flights from South Carolina to Indianapolis, such as Alaska Airlines, Southwest and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Alaska Airlines
8.0
Very good
9,818 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Southwest
8.0
Very good
4,276 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Delta
8.0
Very good
7,899 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
United Airlines
7.4
Good
8,614 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Allegiant Air
7.3
Good
731 reviews
Alaska Airlines
8.0
Very good
9,818 reviews

Food

7.1

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from South Carolina?

    Indianapolis (IND) is the airport you will fly into if you book a flight from South Carolina to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How popular is this South Carolina to Indianapolis flight route?

    The South Carolina to Indianapolis flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from South Carolina to Indianapolis one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $45. However, be on the lookout for offers from Spirit Airlines and Frontier, as they are both options that can get you from South Carolina to Indianapolis for a low price.

  • What are the most popular routes from South Carolina to Indianapolis?

    When deciding which route to take from South Carolina to Indianapolis consider Charlotte Douglas - Indianapolis, Greenville - Indianapolis or Charleston - Indianapolis as they are the most popular.

  • Can I find deals for flights from South Carolina to Indianapolis that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indianapolis.

  • Can I find deals for business class flights from South Carolina to Indianapolis?

    Yes. Cheapflights offers flight deals from South Carolina to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Greenwood
Bloomington
Terre Haute
Noblesville
Fishers
Carmel
Anderson
Kokomo
Franklin
Plainfield
Crawfordsville
Muncie
Shelbyville
Speedway

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Indianapolis

Discover the top 6 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$67Average$146FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$108Average$233FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$195Average$381FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$358FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$228Average$442FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$286Average$402FlexibilityNo cancel feeOn-time63%
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