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$125+ Cheap flights from Santa Fe (SAF) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
SAF — IND
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Santa Fe to Indiana

Cheapest flights from Santa Fe to Indiana
Explore the most affordable flight options available from Santa Fe to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:27 pmSAF - ORD
1 stop7h 49mAmerican Airlines
Sat 1/36:00 amORD - SAF
1 stop8h 00mAmerican Airlines
Deal found 12/11$364
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:30 pmSAF - ORD
Nonstop2h 58mAmerican Airlines
Mon 12/292:50 pmORD - SAF
1 stop8h 08mAmerican Airlines
Deal found 12/10$420
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/283:27 pmSAF - ORD
1 stop7h 49mAmerican Airlines
Sun 1/46:00 amORD - SAF
1 stop8h 00mAmerican Airlines
Deal found 12/11$424
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:30 pmSAF - ORD
Nonstop2h 58mAmerican Airlines
Thu 1/18:15 amORD - SAF
1 stop7h 42mAmerican Airlines
Deal found 12/11$442
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/241:30 pmSAF - ORD
Nonstop2h 58mAmerican Airlines
Wed 12/3110:29 amORD - SAF
1 stop6h 43mAmerican Airlines
Deal found 12/10$444
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:00 amSAF - ORD
1 stop4h 59mUnited Airlines
Wed 12/318:02 pmORD - SAF
2 stops14h 37mUnited Airlines
Deal found 12/10$494
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amSAF - SDF
2 stops10h 11mUnited Airlines
Mon 12/293:18 pmSDF - SAF
1 stop20h 21mUnited Airlines
Deal found 12/10$583
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:54 pmSAF - SDF
1 stop6h 40mAmerican Airlines
Mon 12/296:19 pmSDF - SAF
1 stop5h 39mAmerican Airlines
Deal found 12/10$599
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/291:30 pmSAF - CVG
1 stop6h 39mAmerican Airlines
Sat 1/35:40 amCVG - SAF
1 stop5h 55mAmerican Airlines
Deal found 12/10$628
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:02 pmSAF - CVG
2 stops17h 15mUnited Airlines
Sat 1/35:45 pmCVG - SAF
2 stops17h 54mUnited Airlines
Deal found 12/10$797
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/231:22 pmSAF - CVG
1 stop6h 50mUnited Airlines
Sun 12/283:18 pmCVG - SAF
1 stop20h 21mUnited Airlines
Deal found 12/11$838

Find flight deals from Santa Fe to Indiana

Keep the following information in mind while searching for Santa Fe to Indiana flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$254
(American Airlines)

One-way from

$125
(United Airlines)

Popular in

March

Cheapest in

February

Average price

$484
Provider with most accurate pricing for Santa Fe-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Fe-Indianapolis flights.
Search Deals
From Santa Fe to Indiana
Search Deals
One-way flight from Santa Fe to Indiana
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($38 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Fe to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Santa Fe to Indiana that are best for you.

Fly from

Santa Fe

Fly to

Indiana

Route

Depart

Return

Price

Santa FeLouisville

SAF - SDF

SAFSDF

Santa Fe

Sat 1/10

7:00 am-2:26 pm

1 stop5h 26m

Louisville Intl

Sat 1/17

9:00 am-12:39 pm

1 stop5h 39m

$274

Santa FeChicago

SAF - ORD

SAFORD

Santa Fe

Wed 3/25

2:33 pm-6:39 pm

Nonstop3h 06m

Chicago O'Hare Intl

Tue 3/31

11:43 am-2:03 pm

Nonstop3h 20m

$275

Santa FeLouisville

SAF - SDF

SAFSDF

Santa Fe

Sat 1/17

7:00 am-2:26 pm

1 stop5h 26m

Louisville Intl

Wed 1/21

9:00 am-12:39 pm

1 stop5h 39m

$334

Santa FeCincinnati

SAF - CVG

SAFCVG

Santa Fe

Sat 1/31

1:16 pm-10:23 pm

1 stop7h 07m

Cincinnati Cinci./N. Kentucky

Tue 2/3

3:29 pm-8:47 pm

1 stop7h 18m

$334

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Sat 1/17

7:00 am-2:39 pm

1 stop5h 39m

Indianapolis

Wed 1/21

9:00 am-2:54 pm

1 stop7h 54m

$334

Santa FeIndianapolis

SAF - IND

SAFIND

Santa Fe

Wed 1/7

10:45 am-8:02 pm

2 stops7h 17m

Indianapolis

Wed 1/14

9:00 am-12:39 pm

1 stop5h 39m

$344

Santa FeChicago

SAF - ORD

SAFORD

Santa Fe

Tue 12/23

3:27 pm-12:16 am

1 stop7h 49m

Chicago O'Hare Intl

Sat 1/3

6:00 am-1:00 pm

1 stop8h 00m

$364

Santa FeChicago

SAF - ORD

SAFORD

Santa Fe

Tue 3/24

2:33 pm-6:39 pm

Nonstop3h 06m

Chicago O'Hare Intl

Wed 4/1

6:00 am-1:09 pm

1 stop8h 09m

$365

Santa FeChicago

SAF - ORD

SAFORD

Santa Fe

Wed 3/25

2:33 pm-6:39 pm

Nonstop3h 06m

Chicago O'Hare Intl

Wed 4/1

6:00 am-1:09 pm

1 stop8h 09m

$365

Santa FeChicago

SAF - ORD

SAFORD

Santa Fe

Tue 3/24

3:33 pm-12:51 am

1 stop8h 18m

Chicago O'Hare Intl

Tue 3/31

6:00 am-1:09 pm

1 stop8h 09m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 29 results
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Best time to book a flight from Santa Fe to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Santa Fe with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Fe to Indiana

What is the cheapest month to book a flight from Santa Fe to Indiana?

Currently, January is the cheapest month in which you can book a flight from Santa Fe to Indiana (average of $175). Flying from Santa Fe to Indiana in December is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santa Fe to Indiana?

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with American Airlines from Santa Fe to Indiana by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Boarding

7.5

Food

6.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Boarding

7.5

Food

6.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Santa Fe to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Fe to Indiana?

    Santa Fe (SAF), located 9.8 mi from the city center, is the airport you fly out of when you book flights from Santa Fe to Indiana.

  • How long is the flight from Santa Fe to Indiana?

    For as low as $275, United Airlines can have you in Indiana from Santa Fe in 3h 06m. Airlines will cover a distance of 1070 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Santa Fe to Indiana?

    When deciding which route to take from Santa Fe to Indiana consider Santa Fe - Chicago O'Hare Intl, Santa Fe - Louisville Intl or Santa Fe - Cincinnati Cinci./N. Kentucky as they are the most popular.

  • Can I find deals for flights from Santa Fe to Indiana that include hotel bookings?

    Yes. In addition to deals on Santa Fe to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Fe to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Fe to Indiana.

  • Can I find deals for business class flights from Santa Fe to Indiana?

    Yes. Cheapflights offers flight deals from Santa Fe to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Fe to Indiana?

    Currently, January is the cheapest month in which you can book a flight from Santa Fe to Indiana (average of $175). Flying from Santa Fe to Indiana in December is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Santa Fe to Indiana

Discover the top airline that operate flights from Santa Fe to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$254Average$415FlexibilityNo cancel feeOn-time71%

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