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$49+ Cheap flights from Missouri to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — IND
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Missouri to Indiana

Keep the following information in mind while searching for Missouri to Indiana flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$102
(Southwest)

One-way from

$49
(Southwest)

Popular in

March

Cheapest in

August

Average price

$358

Good round-trip deal

$273 or less

Good one-way deal

$183 or less
Provider with most accurate pricing for Kansas City-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Kansas City-Indianapolis flights.
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From Missouri to Indiana
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One-way flight from Missouri to Indiana
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Highest demand for flights based on searches. 16% potential increase in price ($68 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Missouri to Indiana.
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Price to beat on a one-way flight from Missouri to Indiana.
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Find flight deals from Missouri to Indiana

Cheapest flights from Missouri to Indiana
Explore the most affordable flight options available from Missouri to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/105:15 amSTL - ORD
1 stop6h 35mSouthwest
Tue 6/101:50 pmORD - STL
2 stops9h 15mSouthwest
Deal found 4/23$102
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/158:55 pmSTL - MDW
Nonstop1h 05mSouthwest
Sat 5/178:35 pmMDW - STL
Nonstop1h 15mSouthwest
Deal found 4/23$114
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:00 amSTL - ORD
Nonstop1h 19mAmerican Airlines
Sat 5/1710:30 pmORD - STL
Nonstop1h 21mAmerican Airlines
Deal found 4/23$121
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/95:00 amSTL - ORD
Nonstop1h 30mUnited Airlines
Tue 8/122:23 pmORD - STL
Nonstop1h 24mUnited Airlines
Deal found 4/24$137
This Southern / Mokulele deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southern / Mokulele is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:15 pmSTL - ORD
1 stop14h 25mSouthern / Mokulele
Thu 5/298:25 amORD - STL
1 stop11h 45mSouthern / Mokulele
Deal found 4/23$140
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/46:33 pmMCI - IND
1 stop4h 30mAmerican Airlines
Tue 6/245:29 pmIND - MCI
1 stop4h 50mAmerican Airlines
Deal found 4/22$159
This Frontier deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:45 pmSTL - MDW
1 stop18h 39mFrontier
Mon 5/196:15 amMDW - STL
1 stop14h 50mFrontier
Deal found 4/23$160
This FlightHub deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2112:15 pmSTL - ORD
1 stop19h 25mMultiple Airlines
Wed 5/285:03 pmORD - STL
1 stop6h 41mMultiple Airlines
Deal found 4/23$167
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:30 amMCI - CVG
1 stop7h 30mAmerican Airlines
Tue 6/37:05 amCVG - MCI
1 stop10h 40mAmerican Airlines
Deal found 4/22$171
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/25:35 pmMCI - IND
1 stop4h 48mDelta
Tue 6/2410:20 amIND - MCI
1 stop4h 02mDelta
Deal found 4/22$177
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2111:32 amSTL - MDW
1 stop6h 13mDelta
Wed 5/289:16 amMDW - STL
1 stop4h 03mDelta
Deal found 4/23$177
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/912:10 pmSTL - ORD
1 stop4h 40mDelta
Tue 8/128:55 amORD - STL
1 stop4h 21mDelta
Deal found 4/24$177

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Missouri to Indiana that are best for you.

Fly from

Missouri

Fly to

Indiana

Route

Depart

Return

Price

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 6/10

5:15 am-11:50 am

1 stop6h 35m

Chicago O'Hare Intl

Tue 6/10

1:50 pm-11:05 pm

2 stops9h 15m

$102

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Thu 5/15

8:55 pm-10:00 pm

Nonstop1h 05m

Chicago Midway

Sat 5/17

8:35 pm-9:50 pm

Nonstop1h 15m

$114

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Thu 5/15

5:00 am-6:19 am

Nonstop1h 19m

Chicago O'Hare Intl

Sat 5/17

10:30 pm-11:51 pm

Nonstop1h 21m

$121

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Wed 7/9

5:00 am-6:30 am

Nonstop1h 30m

Chicago O'Hare Intl

Tue 8/12

2:23 pm-3:47 pm

Nonstop1h 24m

$137

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Thu 5/15

5:15 pm-7:40 am

1 stop14h 25m

Chicago O'Hare Intl

Thu 5/29

8:25 am-8:10 pm

1 stop11h 45m

$140

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Wed 6/4

6:33 pm-12:03 am

1 stop4h 30m

Indianapolis

Tue 6/24

5:29 pm-9:19 pm

1 stop4h 50m

$159

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Thu 5/15

5:45 pm-12:24 pm

1 stop18h 39m

Chicago Midway

Mon 5/19

6:15 am-9:05 pm

1 stop14h 50m

$160

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Wed 5/21

12:15 pm-7:40 am

1 stop19h 25m

Chicago O'Hare Intl

Wed 5/28

5:03 pm-11:44 pm

1 stop6h 41m

$167

Kansas CityCincinnati

MCI - CVG

MCICVG

Kansas City

Thu 5/29

5:30 am-2:00 pm

1 stop7h 30m

Cincinnati Cinci./N. Kentucky

Tue 6/3

7:05 am-4:45 pm

1 stop10h 40m

$171

Kansas CityIndianapolis

MCI - IND

MCIIND

Kansas City

Mon 6/2

5:35 pm-11:23 pm

1 stop4h 48m

Indianapolis

Wed 6/25

8:10 am-1:22 pm

1 stop6h 12m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Indiana

What is the cheapest month to book a flight from Missouri to Indiana?

Currently, August is the cheapest month in which you can book a flight from Missouri to Indiana (average of $297). Flying from Missouri to Indiana in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IN?

Find hourly flight availability from Missouri to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Indiana as you normally would.

Rainfall in Indiana by month

Plan your trip to Indiana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indiana ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indiana when rainfall is around 2.3 in.

Temperature in Indiana by month

Plan your trip to Indiana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated April 24, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Missouri to Indiana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Food

7.1

Boarding

8.2

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,918 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Food

7.1

Boarding

8.2

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Southwest
8.0
Very good
4,286 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Food

7.1

Boarding

8.2

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,920 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Food

7.1

Boarding

8.2

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,685 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Food

7.1

Boarding

8.2

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Allegiant Air
7.3
Good
734 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Crew

8.5

Food

7.1

Boarding

8.2

Entertainment

7.1

Overall

8.0

Comfort

7.9

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Missouri to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Indiana one-way?

    One-way options have recently been found by users for as low as $49 on Southwest. Other airlines that offer cheap prices include United Airlines from $69 and Southern / Mokulele from $78 one-way.

  • Can I find deals for flights from Missouri to Indiana that include hotel bookings?

    Yes. In addition to deals on Missouri to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Indiana.

  • Can I find deals for business class flights from Missouri to Indiana?

    Yes. Cheapflights offers flight deals from Missouri to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Indiana (average of $297). Flying from Missouri to Indiana in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Indiana

Discover the top 4 airlines that operate flights from Missouri to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$136Average$284FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$183Average$331FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$207Average$413FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$273Average$379FlexibilityNo cancel feeOn-time63%

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