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$55+ Cheap flights from Missouri to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — IND
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Missouri to Indiana

Keep the following information in mind while searching for Missouri to Indiana flight deals. Data was last updated February 20, 2025.

Round-trip from

$120
(American Airlines)

One-way from

$55
(Frontier)

Good round-trip deal

$391 or less

Good one-way deal

$254 or less
From Missouri to Indiana
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One-way flight from Missouri to Indiana
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Price to beat on a round-trip flight from Missouri to Indiana.
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Price to beat on a one-way flight from Missouri to Indiana.
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Find flight deals from Missouri to Indiana

Cheapest flights from Missouri to Indiana
Explore the most affordable flight options available from Missouri to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/136:00 amSTL - ORD
Nonstop1h 23mAmerican Airlines
Thu 5/1510:21 pmORD - STL
Nonstop1h 20mAmerican Airlines
Deal found 2/20$120
This eDestinos deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1312:15 pmSTL - ORD
1 stop3h 35mSouthern / Mokulele
Thu 5/158:25 amORD - STL
1 stop11h 45mSouthern / Mokulele
Deal found 2/20$123
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/64:00 pmSTL - MDW
1 stop6h 05mSouthwest
Mon 3/104:25 pmMDW - STL
Nonstop1h 15mSouthwest
Deal found 2/20$127
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1411:00 amSTL - ORD
Nonstop1h 17mMultiple Airlines
Mon 3/178:25 amORD - STL
1 stop11h 45mMultiple Airlines
Deal found 2/20$127
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/76:38 pmSTL - CVG
1 stop9h 31mFrontier
Wed 4/92:28 pmCVG - STL
1 stop10h 18mFrontier
Deal found 2/19$130
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/246:55 pmSTL - MDW
1 stop10h 36mFrontier
Mon 4/141:23 pmMDW - STL
1 stop10h 23mFrontier
Deal found 2/20$130
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/135:20 amSTL - ORD
2 stops8h 40mSouthwest
Thu 5/155:45 pmORD - STL
1 stop5h 00mSouthwest
Deal found 2/20$142
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:30 amSTL - ORD
Nonstop1h 31mUnited Airlines
Thu 3/201:01 pmORD - STL
Nonstop1h 22mUnited Airlines
Deal found 2/20$163
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/186:50 amSTL - MDW
1 stop5h 46mDelta
Fri 4/117:09 pmMDW - STL
1 stop3h 55mDelta
Deal found 2/20$177
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/410:30 amSTL - ORD
1 stop5h 41mDelta
Sat 4/196:45 amORD - STL
2 stops10h 01mDelta
Deal found 2/19$182
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/83:49 pmMCI - IND
1 stop5h 06mAmerican Airlines
Tue 4/158:20 amIND - MCI
1 stop7h 39mAmerican Airlines
Deal found 2/20$197
This FlightHub deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/314:21 pmMCI - SDF
1 stop29h 37mSpirit Airlines
Thu 4/312:48 pmSDF - MCI
1 stop28h 29mSpirit Airlines
Deal found 2/19$216

Find flights from Missouri to Indiana within your budget

Customize your flight search to find flights from Missouri to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Missouri

Fly to

Indiana

Route

Depart

Return

Price

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 5/13

6:00 am-7:23 am

Nonstop1h 23m

Chicago O'Hare Intl

Thu 5/15

10:21 pm-11:41 pm

Nonstop1h 20m

$120

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 5/13

12:15 pm-3:50 pm

1 stop3h 35m

Chicago O'Hare Intl

Thu 5/15

8:25 am-8:10 pm

1 stop11h 45m

$123

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Thu 3/6

4:00 pm-10:05 pm

1 stop6h 05m

Chicago Midway

Mon 3/10

4:25 pm-5:40 pm

Nonstop1h 15m

$127

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Fri 3/14

11:00 am-12:17 pm

Nonstop1h 17m

Chicago O'Hare Intl

Mon 3/17

8:25 am-8:10 pm

1 stop11h 45m

$127

St. LouisCincinnati

STL - CVG

STLCVG

Lambert-St Louis

Mon 4/7

6:38 pm-5:09 am

1 stop9h 31m

Cincinnati Cinci./N. Kentucky

Wed 4/9

2:28 pm-11:46 pm

1 stop10h 18m

$130

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Mon 3/24

6:55 pm-5:31 am

1 stop10h 36m

Chicago Midway

Mon 4/14

1:23 pm-11:46 pm

1 stop10h 23m

$130

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 5/13

5:20 am-2:00 pm

2 stops8h 40m

Chicago O'Hare Intl

Thu 5/15

5:45 pm-10:45 pm

1 stop5h 00m

$142

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 3/18

6:30 am-8:01 am

Nonstop1h 31m

Chicago O'Hare Intl

Thu 3/20

1:01 pm-2:23 pm

Nonstop1h 22m

$163

St. LouisChicago

STL - MDW

STLMDW

Lambert-St Louis

Tue 3/18

6:50 am-12:36 pm

1 stop5h 46m

Chicago Midway

Fri 4/11

7:09 pm-11:04 pm

1 stop3h 55m

$177

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Fri 4/4

10:30 am-4:11 pm

1 stop5h 41m

Chicago O'Hare Intl

Sat 4/19

6:45 am-4:46 pm

2 stops10h 01m

$182

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Indiana

Get recent, data-driven insights about flights from Missouri to Indiana including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Indiana?

Currently, August is the cheapest month in which you can book a flight from Missouri to Indiana (average of $297). Flying from Missouri to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to IN?

Find hourly flight availability from Missouri to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Indiana as you normally would.

Rainfall in Indiana by month

Plan your trip to Indiana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indiana ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indiana when rainfall is around 2.3 in.

Temperature in Indiana by month

Plan your trip to Indiana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated February 20, 2025.
Peruse reviews from past customers who have flown with Southwest, Alaska Airlines and Delta from Missouri to Indiana to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Alaska Airlines
8.0
Very good
9,692 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Indiana one-way?

    One-way options have recently been found by users for as low as $55 on Frontier. Other airlines that offer cheap prices include Southwest from $59 and American Airlines from $59 one-way.

  • Can I find deals for flights from Missouri to Indiana that include hotel bookings?

    Yes. In addition to deals on Missouri to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Indiana.

  • Can I find deals for business class flights from Missouri to Indiana?

    Yes. Cheapflights offers flight deals from Missouri to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Indiana (average of $297). Flying from Missouri to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Indiana

Discover the top 4 airlines that operate flights from Missouri to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$149Average$392FlexibilityNo cancel feeOn-time69%
DeltaCheapest$157Average$331FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$168Average$358FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$280Average$365FlexibilityNo cancel feeOn-time63%
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