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$75+ Cheap flights from Knoxville (TYS) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — IND
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Knoxville to Indiana

Keep the following information in mind while searching for Knoxville to Indiana flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$189
(American Airlines)

One-way from

$75
(Frontier)

Popular in

March

Cheapest in

August

Average price

$268
Provider with most accurate pricing for Knoxville McGhee Tyson-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Indianapolis flights.
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From Knoxville McGhee Tyson to Indiana
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One-way flight from Knoxville McGhee Tyson to Indiana
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Highest demand for flights based on searches. 9% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Knoxville to Indiana

Cheapest flights from Knoxville to Indiana
Explore the most affordable flight options available from Knoxville to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/118:07 pmTYS - ORD
Nonstop2h 07mAmerican Airlines
Mon 4/144:56 pmORD - TYS
Nonstop1h 42mAmerican Airlines
Deal found 2/19$189
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:00 amTYS - CVG
1 stop17h 04mAllegiant Air
Mon 3/106:30 amCVG - TYS
1 stop8h 03mAllegiant Air
Deal found 2/19$189
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/104:31 pmTYS - MDW
1 stop8h 50mFrontier
Sun 4/136:45 amMDW - TYS
1 stop8h 01mFrontier
Deal found 2/18$190
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/237:00 amTYS - ORD
Nonstop2h 03mUnited Airlines
Sun 3/302:31 pmORD - TYS
Nonstop1h 52mUnited Airlines
Deal found 2/20$190
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/127:15 amTYS - ORD
1 stop12h 11mMultiple Airlines
Tue 3/1812:31 pmORD - TYS
1 stop22h 29mMultiple Airlines
Deal found 2/18$194
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/85:45 amTYS - MDW
1 stop4h 22mDelta
Tue 4/84:59 pmMDW - TYS
1 stop5h 43mDelta
Deal found 2/20$199
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/195:00 pmTYS - ORD
1 stop4h 58mDelta
Wed 3/268:25 amORD - TYS
1 stop7h 29mDelta
Deal found 2/19$199
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/285:30 amTYS - CVG
1 stop4h 54mDelta
Mon 9/15:55 pmCVG - TYS
1 stop5h 52mDelta
Deal found 2/19$219
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:00 amTYS - CVG
2 stops32h 00mMultiple Airlines
Mon 3/106:30 amCVG - TYS
1 stop8h 03mMultiple Airlines
Deal found 2/19$243
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2712:03 pmTYS - IND
1 stop6h 24mAmerican Airlines
Sun 3/26:41 amIND - TYS
1 stop4h 35mAmerican Airlines
Deal found 2/20$249
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/257:17 pmTYS - IND
1 stop4h 42mDelta
Tue 3/46:20 amIND - TYS
1 stop5h 54mDelta
Deal found 2/20$259
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/204:23 pmTYS - ORD
1 stop9h 00mFrontier
Thu 3/276:45 amORD - TYS
1 stop7h 38mFrontier
Deal found 2/20$260

Find flights from Knoxville to Indiana within your budget

Customize your flight search to find flights from Knoxville to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Knoxville

Fly to

Indiana

Route

Depart

Return

Price

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Fri 4/11

8:07 pm-9:14 pm

Nonstop2h 07m

Chicago O'Hare Intl

Mon 4/14

4:56 pm-7:38 pm

Nonstop1h 42m

$189

KnoxvilleCincinnati

TYS - CVG

TYSCVG

Knoxville McGhee Tyson

Thu 3/6

6:00 am-11:04 pm

1 stop17h 04m

Cincinnati Cinci./N. Kentucky

Mon 3/10

6:30 am-2:33 pm

1 stop8h 03m

$189

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Thu 4/10

4:31 pm-12:21 am

1 stop8h 50m

Chicago Midway

Sun 4/13

6:45 am-3:46 pm

1 stop8h 01m

$190

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Sun 3/23

7:00 am-8:03 am

Nonstop2h 03m

Chicago O'Hare Intl

Sun 3/30

2:31 pm-5:23 pm

Nonstop1h 52m

$190

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 3/12

7:15 am-6:26 pm

1 stop12h 11m

Chicago O'Hare Intl

Tue 3/18

12:31 pm-12:00 pm

1 stop22h 29m

$194

KnoxvilleChicago

TYS - MDW

TYSMDW

Knoxville McGhee Tyson

Tue 4/8

5:45 am-9:07 am

1 stop4h 22m

Chicago Midway

Tue 4/8

4:59 pm-11:42 pm

1 stop5h 43m

$199

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Wed 3/19

5:00 pm-8:58 pm

1 stop4h 58m

Chicago O'Hare Intl

Wed 3/26

8:25 am-4:54 pm

1 stop7h 29m

$199

KnoxvilleCincinnati

TYS - CVG

TYSCVG

Knoxville McGhee Tyson

Thu 3/6

6:00 am-2:00 pm

2 stops32h 00m

Cincinnati Cinci./N. Kentucky

Mon 3/10

6:30 am-2:33 pm

1 stop8h 03m

$243

KnoxvilleChicago

TYS - ORD

TYSORD

Knoxville McGhee Tyson

Thu 3/20

4:23 pm-12:23 am

1 stop9h 00m

Chicago O'Hare Intl

Thu 3/27

6:45 am-3:23 pm

1 stop7h 38m

$260

KnoxvilleIndianapolis

TYS - IND

TYSIND

Knoxville McGhee Tyson

Sat 3/8

7:00 am-1:03 pm

1 stop6h 03m

Indianapolis

Wed 3/12

10:10 am-3:04 pm

1 stop4h 54m

$290

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Showing 1-10 of 33 results
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Best time to book a flight from Knoxville to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Indiana

Get recent, data-driven insights about flights from Knoxville to Indiana including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Indiana?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $297). Flying from Knoxville to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to IN?

Find hourly flight availability from Knoxville to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Knoxville to Indiana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Indiana by month

Plan your trip to Indiana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indiana ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indiana when rainfall is around 2.3 in.

Temperature in Indiana by month

Plan your trip to Indiana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated February 20, 2025.
See what other customers who have flown with Delta, United Airlines and Allegiant Air from Knoxville to Indiana have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.3
Good
765 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Frontier
6.0
Okay
3,355 reviews
Delta
8.0
Very good
8,219 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Indiana?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Indiana. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Indiana one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $75. American Airlines flights start at $90 while deals on Allegiant Air start at $99 one-way.

  • What are the most popular routes from Knoxville to Indiana?

    When deciding which route to take from Knoxville to Indiana consider Knoxville McGhee Tyson - Chicago O'Hare Intl, Knoxville McGhee Tyson - Chicago Midway or Knoxville McGhee Tyson - Indianapolis as they are the most popular.

  • Can I find deals for flights from Knoxville to Indiana that include hotel bookings?

    Yes. In addition to deals on Knoxville to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Indiana.

  • Can I find deals for business class flights from Knoxville to Indiana?

    Yes. Cheapflights offers flight deals from Knoxville to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Indiana (average of $297). Flying from Knoxville to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Knoxville to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Knoxville to Indiana

Discover the top 4 airlines that operate flights from Knoxville to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$65Average$79FlexibilityNo cancel feeOn-time88%
DeltaCheapest$217Average$278FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$217Average$302FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$223Average$257FlexibilityNo cancel feeOn-time69%
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