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$100+ Cheap flights from South Carolina to Harrisburg (MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDT
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from South Carolina to Harrisburg

Keep the following information in mind while searching for South Carolina to Harrisburg flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$101
(Booking.com)

One-way from

$100
(American Airlines)

Popular in

February

Cheapest in

June

Average price

$199
Provider with most accurate pricing for Myrtle Beach Intl-Harrisburg flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Harrisburg flights.
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From South Carolina to Harrisburg
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One-way flight from South Carolina to Harrisburg
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Highest demand for flights based on searches. 23% potential increase in price ($79 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from South Carolina to Harrisburg

Cheapest flights from South Carolina to Harrisburg
Explore the most affordable flight options available from South Carolina to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/266:55 pmMYR - MDT
Nonstop1h 32mAllegiant Air
Sat 6/284:32 pmMDT - MYR
Nonstop1h 31mAllegiant Air
Deal found 4/23$101
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/47:00 amGSP - MDT
1 stop4h 53mDelta
Sun 7/65:01 pmMDT - GSP
1 stop4h 40mDelta
Deal found 4/22$214
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/26:00 amMYR - MDT
1 stop5h 09mDelta
Sun 7/66:10 amMDT - MYR
1 stop4h 15mDelta
Deal found 4/23$214
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/307:31 amSAV - MDT
1 stop4h 06mAmerican Airlines
Sun 6/15:00 amMDT - SAV
1 stop5h 28mAmerican Airlines
Deal found 4/23$224
This Booking.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/309:01 pmCLT - MDT
1 stop22h 26mFrontier
Sun 6/111:26 amMDT - CLT
1 stop27h 01mFrontier
Deal found 4/23$230
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/158:51 pmMYR - MDT
1 stop3h 04mAmerican Airlines
Sat 8/231:57 pmMDT - MYR
2 stops4h 59mAmerican Airlines
Deal found 4/23$234
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/510:17 pmGSP - MDT
1 stop10h 04mAllegiant Air
Sun 6/86:53 pmMDT - GSP
1 stop25h 40mAllegiant Air
Deal found 4/21$246
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/168:43 pmCHS - MDT
1 stop3h 12mAmerican Airlines
Sun 5/185:00 amMDT - CHS
1 stop3h 24mAmerican Airlines
Deal found 4/23$249
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:30 amSAV - MDT
2 stops6h 27mDelta
Mon 10/65:58 pmMDT - SAV
1 stop6h 01mDelta
Deal found 4/23$254
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/59:43 amCHS - MDT
1 stop8h 20mMultiple Airlines
Sun 6/86:53 pmMDT - CHS
2 stops18h 15mMultiple Airlines
Deal found 4/22$258
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/256:20 pmGSP - MDT
1 stop3h 39mAmerican Airlines
Sun 4/275:00 amMDT - GSP
1 stop3h 26mAmerican Airlines
Deal found 4/21$289
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/64:59 pmCHS - MDT
1 stop6h 46mDelta
Sun 6/86:25 pmMDT - CHS
1 stop5h 34mDelta
Deal found 4/22$294

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Harrisburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from South Carolina to Harrisburg that are best for you.

Fly from

South Carolina

Fly to

Harrisburg

Route

Depart

Return

Price

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Thu 6/26

6:55 pm-8:27 pm

Nonstop1h 32m

Harrisburg

Sat 6/28

4:32 pm-6:03 pm

Nonstop1h 31m

$101

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Fri 7/4

7:00 am-11:53 am

1 stop4h 53m

Harrisburg

Sun 7/6

5:01 pm-9:41 pm

1 stop4h 40m

$214

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Wed 7/2

6:00 am-11:09 am

1 stop5h 09m

Harrisburg

Sun 7/6

6:10 am-10:25 am

1 stop4h 15m

$214

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Fri 5/30

7:31 am-11:37 am

1 stop4h 06m

Harrisburg

Sun 6/1

5:00 am-10:28 am

1 stop5h 28m

$224

CharlotteHarrisburg

CLT - MDT

CLTMDT

Charlotte Douglas

Fri 5/30

9:01 pm-7:27 pm

1 stop22h 26m

Harrisburg

Sun 6/1

11:26 am-2:27 pm

1 stop27h 01m

$230

Myrtle BeachHarrisburg

MYR - MDT

MYRMDT

Myrtle Beach Intl

Fri 8/15

8:51 pm-11:55 pm

1 stop3h 04m

Harrisburg

Sat 8/23

1:57 pm-6:56 pm

2 stops4h 59m

$234

GreenvilleHarrisburg

GSP - MDT

GSPMDT

Greenville

Thu 6/5

10:17 pm-8:21 am

1 stop10h 04m

Harrisburg

Sun 6/8

6:53 pm-8:33 pm

1 stop25h 40m

$246

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Fri 5/16

8:43 pm-11:55 pm

1 stop3h 12m

Harrisburg

Sun 5/18

5:00 am-8:24 am

1 stop3h 24m

$249

SavannahHarrisburg

SAV - MDT

SAVMDT

Savannah/Hilton Head

Wed 10/1

5:30 am-11:57 am

2 stops6h 27m

Harrisburg

Mon 10/6

5:58 pm-11:59 pm

1 stop6h 01m

$254

CharlestonHarrisburg

CHS - MDT

CHSMDT

Charleston

Thu 6/5

9:43 am-6:03 pm

1 stop8h 20m

Harrisburg

Sun 6/8

6:53 pm-1:08 pm

2 stops18h 15m

$258

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 39 results
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Best time to book a flight from South Carolina to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Harrisburg

What is the cheapest month to book a flight from South Carolina to Harrisburg?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $355). Flying from South Carolina to Harrisburg in June is currently the most expensive (average of $453). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDT?

Find hourly flight availability from South Carolina to Harrisburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

When flying from South Carolina to Harrisburg, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Harrisburg by month

Plan your trip to Harrisburg by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Harrisburg ranges from 2.7 - 4.1 inches per month. May is typically the wettest month, when rainfall can reach 4.1 in. February is typically the driest time to visit Harrisburg when rainfall is around 2.7 in.

Temperature in Harrisburg by month

Plan your trip to Harrisburg by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Harrisburg, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

Reviews of airlines servicing Harrisburg

Get insights into the airlines that provide service to Harrisburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Harrisburg. Reviews last updated April 24, 2025.
To help decide which airline to fly from South Carolina to Harrisburg, see what other customers have to say about Delta, United Airlines and Allegiant Air. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,685 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Frontier
6.0
Okay
3,283 reviews
Delta
8.0
Very good
7,920 reviews

Comfort

7.9

Crew

8.5

Overall

8.0

Entertainment

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Harrisburg from South Carolina?

    Harrisburg (MDT) is the airport you will fly into if you book a flight from South Carolina to Harrisburg. It is only a 8.5 mi journey from Harrisburg (MDT) to Harrisburg’s city center.

  • What are the cheapest airlines to fly from South Carolina to Harrisburg one-way?

    One-way options have recently been found by users for as low as $100 on American Airlines. Other airlines that offer cheap prices include Delta from $114 and Frontier from $121 one-way.

  • What are the most popular routes from South Carolina to Harrisburg?

    When deciding which route to take from South Carolina to Harrisburg consider Charlotte Douglas - Harrisburg, Charleston - Harrisburg or Myrtle Beach Intl - Harrisburg as they are the most popular.

  • Can I find deals for flights from South Carolina to Harrisburg that include hotel bookings?

    Yes. In addition to deals on South Carolina to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Harrisburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Harrisburg.

  • Can I find deals for business class flights from South Carolina to Harrisburg?

    Yes. Cheapflights offers flight deals from South Carolina to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Harrisburg?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Harrisburg (average of $355). Flying from South Carolina to Harrisburg in June is currently the most expensive (average of $453). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Carlisle
Hershey
Mechanicsburg
Camp Hill

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Alternative routes for South Carolina to Harrisburg

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to Harrisburg

Discover the top 4 airlines that operate flights from South Carolina to Harrisburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$106Average$134FlexibilityNo cancel feeOn-time88%
DeltaCheapest$198Average$303FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$352FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$318FlexibilityNo cancel feeOn-time69%

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