Guayaquil

$179+ Cheap flights from South Carolina to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GYE
Apr 7 — Apr 141
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Cheap flight deals from South Carolina to Guayaquil

Keep the following information in mind while searching for South Carolina to Guayaquil flight deals. Data was last updated April 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$467
(Avianca Connect)

One-way from

$179
(Avianca Connect)
Provider with most accurate pricing for Myrtle Beach Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Guayaquil Jose Joaquin de Olmedo flights.
From South Carolina to Guayaquil Jose Joaquin de Olmedo
One-way flight from South Carolina to Guayaquil Jose Joaquin de Olmedo

Find flight deals from South Carolina to Guayaquil

Cheapest flights from South Carolina to Guayaquil
Explore the most affordable flight options available from South Carolina to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

This Avianca Connect deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:58 amCLT - GYE
2 stops16h 42mMultiple Airlines
Wed 5/73:35 amGYE - CLT
2 stops15h 22mMultiple Airlines
Deal found 4/1$467
This United deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/3011:00 amCLT - GYE
2 stops25h 17mUnited Airlines
Sun 6/812:17 pmGYE - CLT
2 stops20h 29mUnited Airlines
Deal found 4/2$547
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/177:00 amCHS - GYE
2 stops29h 17mUnited Airlines
Sat 5/248:31 amGYE - CHS
2 stops23h 16mUnited Airlines
Deal found 4/1$599
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:35 amCLT - GYE
1 stop14h 25mAmerican Airlines
Sat 9/137:30 amGYE - CLT
1 stop12h 12mAmerican Airlines
Deal found 4/1$659
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/163:35 pmCHS - GYE
3 stops43h 20mMultiple Airlines
Thu 5/223:35 amGYE - CHS
3 stops28h 03mMultiple Airlines
Deal found 3/31$692
This oojo deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/116:00 amCLT - GYE
2 stops41h 40mAvianca
Fri 5/233:35 amGYE - CLT
2 stops29h 15mAvianca
Deal found 4/2$849
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/177:38 amCHS - GYE
2 stops14h 32mAmerican Airlines
Sat 5/246:00 amGYE - CHS
1 stop12h 08mAmerican Airlines
Deal found 4/1$872
This Copa Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/186:00 amCLT - GYE
2 stops18h 57mCopa Airlines
Mon 8/42:45 pmGYE - CLT
2 stops18h 03mCopa Airlines
Deal found 4/1$897
This LATAM Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/67:37 pmCLT - GYE
2 stops16h 33mLATAM Airlines
Wed 4/93:13 pmGYE - CLT
2 stops18h 53mLATAM Airlines
Deal found 3/31$1,165

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
Use the filters below to find and compare flights from South Carolina to Guayaquil that are best for you.

Fly from

South Carolina

Fly to

Guayaquil

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 5/1

6:58 am-10:40 pm

2 stops16h 42m

Guayaquil Jose Joaquin de Olmedo

Wed 5/7

3:35 am-7:57 pm

2 stops15h 22m

$467

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Fri 5/30

11:00 am-11:17 am

2 stops25h 17m

Guayaquil Jose Joaquin de Olmedo

Sun 6/8

12:17 pm-9:46 am

2 stops20h 29m

$547

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Sat 5/17

7:00 am-11:17 am

2 stops29h 17m

Guayaquil Jose Joaquin de Olmedo

Sat 5/24

8:31 am-8:47 am

2 stops23h 16m

$599

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Fri 9/5

5:35 am-7:00 pm

1 stop14h 25m

Guayaquil Jose Joaquin de Olmedo

Sat 9/13

7:30 am-8:42 pm

1 stop12h 12m

$659

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 5/16

3:35 pm-9:55 am

3 stops43h 20m

Guayaquil Jose Joaquin de Olmedo

Thu 5/22

3:35 am-8:38 am

3 stops28h 03m

$692

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sun 5/11

6:00 am-10:40 pm

2 stops41h 40m

Guayaquil Jose Joaquin de Olmedo

Fri 5/23

3:35 am-9:50 am

2 stops29h 15m

$849

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Sat 5/17

7:38 am-9:10 pm

2 stops14h 32m

Guayaquil Jose Joaquin de Olmedo

Sat 5/24

6:00 am-7:08 pm

1 stop12h 08m

$872

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Fri 7/18

6:00 am-11:57 pm

2 stops18h 57m

Guayaquil Jose Joaquin de Olmedo

Mon 8/4

2:45 pm-9:48 am

2 stops18h 03m

$897

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Wed 4/16

12:08 pm-11:20 pm

2 stops12h 12m

$179

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Fri 5/9

8:50 am-11:20 pm

2 stops15h 30m

$182

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 17 results
1
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Best time to book a flight from South Carolina to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Guayaquil

What is the cheapest time of day to fly from SC to GYE?

Find hourly flight availability from South Carolina to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

When flying from South Carolina to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

Temperature in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated April 2, 2025.
To help decide which airline to fly from South Carolina to Guayaquil, see what other customers have to say about Delta, Copa Airlines and LATAM Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good
8.0
Very good

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Overall

8.0

Boarding

8.2

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Guayaquil from South Carolina?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from South Carolina to Guayaquil.

  • What are the cheapest airlines to fly from South Carolina to Guayaquil one-way?

    One-way options have recently been found by users for as low as $374 on United Airlines. Other airlines that offer cheap prices include LATAM Airlines from $407 and Delta from $481 one-way.

  • What are the most popular routes from South Carolina to Guayaquil?

  • Can I find deals for flights from South Carolina to Guayaquil that include hotel bookings?

    Yes. In addition to deals on South Carolina to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Guayaquil.

  • Can I find deals for business class flights from South Carolina to Guayaquil?

    Yes. Cheapflights offers flight deals from South Carolina to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Guayaquil (average of $440). Flying from South Carolina to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from South Carolina to Guayaquil

Discover the top airline that operate flights from South Carolina to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$436Average$677FlexibilityNo cancel feeOn-time71%

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