Guayaquil

$187+ Cheap flights from South Carolina to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GYE
Apr 27 — May 41
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Guayaquil

Keep the following information in mind while searching for South Carolina to Guayaquil flight deals. Data was last updated April 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$539
(United Airlines)

One-way from

$187
(Avianca Connect)
Provider with most accurate pricing for Myrtle Beach Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Guayaquil Jose Joaquin de Olmedo flights.
From South Carolina to Guayaquil Jose Joaquin de Olmedo
One-way flight from South Carolina to Guayaquil Jose Joaquin de Olmedo

Find flight deals from South Carolina to Guayaquil

Cheapest flights from South Carolina to Guayaquil
Explore the most affordable flight options available from South Carolina to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

This United deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/17:00 amCLT - GYE
2 stops17h 20mMultiple Airlines
Wed 9/173:35 amGYE - CLT
2 stops17h 22mMultiple Airlines
Deal found 4/21$496
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1111:00 amCLT - GYE
2 stops25h 17mUnited Airlines
Wed 6/252:45 pmGYE - CLT
2 stops30h 12mUnited Airlines
Deal found 4/22$499
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:15 amCLT - GYE
1 stop14h 45mAmerican Airlines
Wed 10/157:30 amGYE - CLT
1 stop9h 54mAmerican Airlines
Deal found 4/21$609
This CheapOair deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/306:52 amCLT - GYE
2 stops38h 26mLATAM Airlines
Mon 7/73:35 pmGYE - CLT
2 stops16h 02mLATAM Airlines
Deal found 4/21$726
This Copa Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/87:40 pmCLT - GYE
2 stops19h 06mCopa Airlines
Tue 8/56:31 pmGYE - CLT
2 stops14h 17mCopa Airlines
Deal found 4/21$727
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1411:40 amCLT - GYE
2 stops27h 35mDelta
Mon 6/238:40 pmGYE - CLT
2 stops35h 20mDelta
Deal found 4/22$757
This Avianca deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/106:00 amCLT - GYE
2 stops21h 05mAvianca
Sat 6/283:15 amGYE - CLT
2 stops29h 33mAvianca
Deal found 4/22$849

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
Use the filters below to find and compare flights from South Carolina to Guayaquil that are best for you.

Fly from

South Carolina

Fly to

Guayaquil

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Mon 9/1

7:00 am-11:20 pm

2 stops17h 20m

Guayaquil Jose Joaquin de Olmedo

Wed 9/17

3:35 am-9:57 pm

2 stops17h 22m

$496

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 6/11

11:00 am-11:17 am

2 stops25h 17m

Guayaquil Jose Joaquin de Olmedo

Wed 6/25

2:45 pm-9:57 pm

2 stops30h 12m

$499

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Thu 10/9

5:15 am-7:00 pm

1 stop14h 45m

Guayaquil Jose Joaquin de Olmedo

Wed 10/15

7:30 am-6:24 pm

1 stop9h 54m

$609

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Mon 6/30

6:52 am-8:18 pm

2 stops38h 26m

Guayaquil Jose Joaquin de Olmedo

Mon 7/7

3:35 pm-8:37 am

2 stops16h 02m

$726

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 7/8

7:40 pm-1:46 pm

2 stops19h 06m

Guayaquil Jose Joaquin de Olmedo

Tue 8/5

6:31 pm-9:48 am

2 stops14h 17m

$727

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Sat 6/14

2:43 pm-2:15 pm

2 stops24h 32m

Guayaquil Jose Joaquin de Olmedo

Tue 6/24

8:40 pm-11:59 pm

2 stops26h 19m

$752

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 6/10

6:00 am-2:05 am

2 stops21h 05m

Guayaquil Jose Joaquin de Olmedo

Sat 6/28

3:15 am-9:48 am

2 stops29h 33m

$849

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Mon 6/16

11:28 am-11:20 pm

2 stops12h 52m

$187

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Wed 6/4

6:00 am-8:25 pm

2 stops15h 25m

$203

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Sat 5/3

6:59 pm-4:43 am

1 stop10h 44m

$287

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 15 results
1
2

Best time to book a flight from South Carolina to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Guayaquil

What is the cheapest time of day to fly from SC to GYE?

Find hourly flight availability from South Carolina to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

When flying from South Carolina to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

Temperature in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated April 22, 2025.
To help decide which airline to fly from South Carolina to Guayaquil, see what other customers have to say about LATAM Airlines, Copa Airlines and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.0

Crew

8.1

Food

6.7

Boarding

7.6

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Entertainment

7.0

Crew

8.1

Food

6.7

Boarding

7.6

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Entertainment

7.0

Crew

8.1

Food

6.7

Boarding

7.6

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Entertainment

7.0

Crew

8.1

Food

6.7

Boarding

7.6

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Entertainment

7.0

Crew

8.1

Food

6.7

Boarding

7.6

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Entertainment

7.0

Crew

8.1

Food

6.7

Boarding

7.6

Comfort

7.4

Overall

7.5

Reviews

1 / 20
6.0
Good

Anonymous,Mar 2025

MCO - BOG

The problem was the delayed departure for airport reason I understood it was not a Latam responsibility. The crew could give something to drink and not only a candy.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Guayaquil from South Carolina?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from South Carolina to Guayaquil.

  • What are the cheapest airlines to fly from South Carolina to Guayaquil one-way?

    One-way options have recently been found by users for as low as $287 on JetBlue. Other airlines that offer cheap prices include Avianca from $410 and United Airlines from $419 one-way.

  • What are the most popular routes from South Carolina to Guayaquil?

  • Can I find deals for flights from South Carolina to Guayaquil that include hotel bookings?

    Yes. In addition to deals on South Carolina to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Guayaquil.

  • Can I find deals for business class flights from South Carolina to Guayaquil?

    Yes. Cheapflights offers flight deals from South Carolina to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Guayaquil (average of $440). Flying from South Carolina to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from South Carolina to Guayaquil

Discover the top airline that operate flights from South Carolina to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$436Average$682FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.