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$161+ Cheap flights from Panama City (PTY) to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/14. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — GYE
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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The best prices from Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo are usually found in February or June, booked 44 days in advance, depart on a Tuesday or Monday and return on a Friday

Cheap flight deals from Panama City to Guayaquil

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Guayaquil (GYE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$314
(Copa Airlines)

One-way from

$161
(Copa Airlines)

Popular in

March

Cheapest in

February

Average price

$278

Good round-trip deal

$307 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Guayaquil Jose Joaquin de Olmedo flights.
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From Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo
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One-way flight from Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo
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Highest demand for flights based on searches. 0% potential increase in price ($3 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo.
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Find flight deals from Panama City to Guayaquil

Cheapest flights from Panama City to Guayaquil
Explore the most affordable flight options available from Panama City to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Copa Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/179:01 amPTY - GYE
Nonstop2h 18mCopa Airlines
Mon 3/246:30 pmGYE - PTY
Nonstop2h 11mCopa Airlines
Deal found 2/19$314
This Avianca deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/123:20 amPTY - GYE
1 stop5h 15mAvianca
Sat 4/199:45 amGYE - PTY
1 stop6h 45mAvianca
Deal found 2/19$315
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/56:35 pmPTY - GYE
1 stop12h 28mMultiple Airlines
Sat 4/128:31 amGYE - PTY
Nonstop2h 10mMultiple Airlines
Deal found 2/19$464
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2011:35 amPTY - GYE
2 stops15h 10mUnited Airlines
Tue 3/253:55 amGYE - PTY
2 stops39h 07mUnited Airlines
Deal found 2/19$1,342

Find flights from Panama City to Guayaquil within your budget

Customize your flight search to find flights from Panama City to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Panama City

Fly to

Guayaquil

Route

Depart

Return

Price

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Mon 3/17

9:01 am-11:19 am

Nonstop2h 18m

Guayaquil Jose Joaquin de Olmedo

Mon 3/24

6:30 pm-8:41 pm

Nonstop2h 11m

$314

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Sat 4/12

3:20 am-8:35 am

1 stop5h 15m

Guayaquil Jose Joaquin de Olmedo

Sat 4/19

9:45 am-4:30 pm

1 stop6h 45m

$315

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Sat 4/5

6:35 pm-7:03 am

1 stop12h 28m

Guayaquil Jose Joaquin de Olmedo

Sat 4/12

8:31 am-10:41 am

Nonstop2h 10m

$464

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Thu 3/20

11:35 am-2:45 am

2 stops15h 10m

Guayaquil Jose Joaquin de Olmedo

Tue 3/25

3:55 am-7:02 pm

2 stops39h 07m

$1,342

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Fri 3/14

3:19 am-12:45 pm

1 stop9h 26m

$161

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Sun 4/13

11:31 am-1:46 pm

Nonstop2h 15m

$222

Panama CityGuayaquil

PTY - GYE

PTYGYE

Panama City Tocumen Intl

Sun 3/2

11:25 am-7:31 pm

2 stops8h 06m

$245

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

  • Most accurate provider: When it comes to deals on Panama City-Guayaquil flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Guayaquil flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Guayaquil flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Guayaquil flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Guayaquil flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to Guayaquil

Get recent, data-driven insights about flights from Panama City to Guayaquil including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Panama City to Guayaquil?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Guayaquil. Price data was last updated on February 14, 2025.

Booking 44 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Guayaquil. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Panama City to Guayaquil (average of $440). Flying from Panama City to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to GYE?

Find hourly flight availability from Panama City to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City to Guayaquil in the morning. If you’re flexible enough to do this you can expect to save up to 40% on your trip compared to booking a flight in the afternoon.

Weekly flight availability from Panama City to Guayaquil

Explore weekly flight availability from Panama City to Guayaquil. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 20, 2025.

The most flights from PTY to GYE are scheduled on a Wednesday (12 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (9 on average).

Rainfall in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

Temperature in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated February 20, 2025.
See what other customers who have flown with Copa Airlines, United Airlines and Avianca from Panama City to Guayaquil have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,510 reviews

Entertainment

6.9

Food

6.9

Crew

8.1

Overall

7.6

Comfort

7.4

Boarding

7.8

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Copa Airlines
7.6
Good
1,510 reviews
Copa Airlines
7.6
Good
1,510 reviews

Entertainment

6.9

Food

6.9

Crew

8.1

Overall

7.6

Comfort

7.4

Boarding

7.8

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

United Airlines
7.4
Good
8,766 reviews
Copa Airlines
7.6
Good
1,510 reviews

Entertainment

6.9

Food

6.9

Crew

8.1

Overall

7.6

Comfort

7.4

Boarding

7.8

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Avianca
6.8
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,510 reviews

Entertainment

6.9

Food

6.9

Crew

8.1

Overall

7.6

Comfort

7.4

Boarding

7.8

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Guayaquil?

    You will need to book a flight from Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo if you want to fly from Panama City to Guayaquil. At least 2 different airlines have flights from Tocumen Intl (PTY) to Jose Joaquin de Olmedo (GYE) on a regular basis. There are 10 flights to Guayaquil from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to GYE to be around 2h 15m.

  • How popular is this Panama City to Guayaquil flight route?

    The Panama City Tocumen Intl to Guayaquil Jose Joaquin de Olmedo flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Panama City to Guayaquil round-trip?

    Flying on Copa Airlines is currently your cheapest option to Guayaquil, with prices starting at $314. Additional round-trip tickets that might be worth considering are offered by Avianca and United Airlines, with the lowest prices starting at $315 and $1,542, respectively.

  • What are the most reliable airlines from Panama City to Guayaquil?

    Consider United Airlines (92%), Copa Airlines (91%) or KLM (87%) when booking your flight. These represent the most reliable airlines when flying from Panama City to Guayaquil.

  • What are the cheapest flights from Panama City to Guayaquil?

    Looking for the cheapest flight from Panama City to Guayaquil? While on average our users pay $307, our data indicates the cheapest price to be $307. The most popular route (Panama City Tocumen Intl - Guayaquil Jose Joaquin de Olmedo), is priced around $332.

  • Can I find deals for flights from Panama City to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Panama City to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Guayaquil.

  • Can I find deals for business class flights from Panama City to Guayaquil?

    Yes. Cheapflights offers flight deals from Panama City to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Guayaquil (average of $440). Flying from Panama City to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to Guayaquil

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Top 2 airlines flying from Panama City to Guayaquil

Discover the top 2 airlines that operate flights from Panama City to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$265Average$304FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$267Average$317FlexibilityNo cancel feeOn-time70%
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