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Guayaquil

$141+ Cheap flights from Ohio to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
CVG — GYE
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Ohio to Guayaquil

Cheapest flights from Ohio to Guayaquil
Explore the most affordable flight options available from Ohio to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:06 pmCLE - GYE
2 stops42h 12mMultiple Airlines
Thu 1/81:26 amGYE - CLE
1 stop12h 19mMultiple Airlines
Deal found 12/11$432
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:43 amCLE - GYE
2 stops23h 35mMultiple Airlines
Thu 1/81:26 amGYE - CLE
1 stop12h 19mMultiple Airlines
Deal found 12/11$460
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:06 pmCLE - GYE
1 stop30h 47mMultiple Airlines
Fri 1/91:26 amGYE - CLE
2 stops21h 47mMultiple Airlines
Deal found 12/11$505
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:06 pmCLE - GYE
1 stop30h 47mMultiple Airlines
Sat 1/101:26 amGYE - CLE
2 stops54h 08mMultiple Airlines
Deal found 12/11$509
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:43 amCLE - GYE
2 stops23h 35mMultiple Airlines
Wed 1/71:26 amGYE - CLE
1 stop12h 19mMultiple Airlines
Deal found 12/11$533
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:43 amCLE - GYE
1 stop12h 10mMultiple Airlines
Sat 1/101:26 amGYE - CLE
2 stops54h 08mMultiple Airlines
Deal found 12/11$537
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:06 pmCLE - GYE
1 stop30h 47mMultiple Airlines
Wed 1/71:26 amGYE - CLE
1 stop12h 19mMultiple Airlines
Deal found 12/11$548
This FlightHub deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:14 amCMH - GYE
1 stop12h 39mSpirit Airlines
Thu 1/81:26 amGYE - CMH
2 stops21h 53mSpirit Airlines
Deal found 12/10$567
This Cheapflightsfares deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2111:43 amCLE - GYE
1 stop12h 10mSpirit Airlines
Wed 1/71:26 amGYE - CLE
1 stop16h 40mSpirit Airlines
Deal found 12/11$598
This KAYAK deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:28 pmCMH - GYE
2 stops29h 25mSpirit Airlines
Wed 1/71:26 amGYE - CMH
1 stop22h 01mSpirit Airlines
Deal found 12/11$605
This FlightHub deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:14 amCMH - GYE
1 stop12h 39mSpirit Airlines
Sun 1/111:26 amGYE - CMH
2 stops21h 53mSpirit Airlines
Deal found 12/10$737

Find flight deals from Ohio to Guayaquil

Keep the following information in mind while searching for Ohio to Guayaquil flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$345
(Kiwi.com)

One-way from

$141
(Kiwi.com)
Provider with most accurate pricing for Cleveland Hopkins Intl-Guayaquil Jose Joaquin de Olmedo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Guayaquil Jose Joaquin de Olmedo flights.
Search Deals
From Ohio to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Ohio to Guayaquil Jose Joaquin de Olmedo
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ohio to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Ohio to Guayaquil that are best for you.

Fly from

Ohio

Fly to

Guayaquil

Route

Depart

Return

Price

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sat 2/7

5:30 am-12:21 am

1 stop18h 51m

Guayaquil Jose Joaquin de Olmedo

Sun 2/22

12:59 am-1:30 pm

2 stops36h 31m

$345

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sat 2/7

5:00 am-12:21 am

2 stops19h 21m

Guayaquil Jose Joaquin de Olmedo

Sun 2/22

12:59 am-9:05 pm

2 stops20h 06m

$346

CincinnatiGuayaquil

CVG - GYE

CVGGYE

Cincinnati Cinci./N. Kentucky

Sat 1/24

9:00 am-12:21 am

2 stops15h 21m

Guayaquil Jose Joaquin de Olmedo

Fri 1/30

1:26 am-9:52 pm

1 stop20h 26m

$352

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sat 1/17

5:05 am-12:21 am

2 stops19h 16m

Guayaquil Jose Joaquin de Olmedo

Sun 1/18

1:26 am-10:08 pm

2 stops20h 42m

$361

CincinnatiGuayaquil

CVG - GYE

CVGGYE

Cincinnati Cinci./N. Kentucky

Wed 2/18

3:20 pm-12:04 am

2 stops32h 44m

Guayaquil Jose Joaquin de Olmedo

Sun 2/22

12:59 am-11:35 am

1 stop10h 36m

$364

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Fri 1/16

5:30 am-12:21 am

1 stop18h 51m

Guayaquil Jose Joaquin de Olmedo

Mon 1/19

6:50 pm-1:30 pm

2 stops18h 40m

$365

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Fri 1/16

5:30 am-12:21 am

1 stop18h 51m

Guayaquil Jose Joaquin de Olmedo

Sun 1/18

1:26 am-11:59 pm

1 stop22h 33m

$405

ClevelandGuayaquil

CLE - GYE

CLEGYE

Cleveland Hopkins Intl

Wed 1/7

11:43 am-11:53 pm

1 stop12h 10m

Guayaquil Jose Joaquin de Olmedo

Tue 2/24

12:59 am-7:14 pm

2 stops18h 15m

$421

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Fri 2/27

8:46 am-12:04 am

1 stop15h 18m

Guayaquil Jose Joaquin de Olmedo

Sat 3/7

6:50 pm-7:07 am

2 stops36h 17m

$425

DetroitGuayaquil

DTW - GYE

DTWGYE

Detroit Metropolitan Wayne County

Sun 2/15

5:45 am-12:04 am

1 stop18h 19m

Guayaquil Jose Joaquin de Olmedo

Fri 2/27

12:59 am-9:35 pm

2 stops20h 36m

$448

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 48 results
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Best time to book a flight from Ohio to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Ohio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ohio to Guayaquil
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Ohio to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Ohio?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from Ohio to Guayaquil.

  • How long is the flight from Ohio to Guayaquil?

    Spirit Airlines, United Airlines, and American Airlines can get you from Ohio to Guayaquil in just under 19h 21m. Your travel time can differ by up to 13h 59m. There are 3072 mi between Ohio and Guayaquil. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Ohio to Guayaquil?

    When deciding which route to take from Ohio to Guayaquil consider Detroit Metropolitan Wayne County - Guayaquil Jose Joaquin de Olmedo, Columbus - Guayaquil Jose Joaquin de Olmedo or Cincinnati Cinci./N. Kentucky - Guayaquil Jose Joaquin de Olmedo as they are the most popular.

  • Can I find deals for flights from Ohio to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Ohio to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ohio to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ohio to Guayaquil.

  • Can I find deals for business class flights from Ohio to Guayaquil?

    Yes. Cheapflights offers flight deals from Ohio to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Ohio to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Ohio to Guayaquil

Discover the top airline that operate flights from Ohio to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$682Average$908FlexibilityNo cancel feeOn-time71%

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