HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guayaquil

$164+ Cheap flights from Missouri to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GYE
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Guayaquil with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Guayaquil

Keep the following information in mind while searching for Missouri to Guayaquil flight deals. Data was last updated February 20, 2025.

Round-trip from

$630
(American Airlines)

One-way from

$398
(Kiwi.com)
From Missouri to Guayaquil Jose Joaquin de Olmedo
Search Deals
One-way flight from Missouri to Guayaquil Jose Joaquin de Olmedo
Search Deals

Find flight deals from Missouri to Guayaquil

Cheapest flights from Missouri to Guayaquil
Explore the most affordable flight options available from Missouri to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This United deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/154:20 pmSTL - GYE
2 stops42h 57mUnited Airlines
Sat 5/312:45 pmGYE - STL
2 stops26h 08mUnited Airlines
Deal found 2/20$630
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/275:37 amMCI - GYE
2 stops15h 16mAmerican Airlines
Tue 5/66:00 amGYE - MCI
2 stops15h 31mAmerican Airlines
Deal found 2/19$640
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/115:31 amSTL - GYE
1 stop15h 29mAmerican Airlines
Tue 9/161:45 pmGYE - STL
1 stop9h 16mAmerican Airlines
Deal found 2/20$657
This United deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/274:35 pmMCI - GYE
2 stops42h 42mUnited Airlines
Mon 5/53:15 amGYE - MCI
2 stops39h 24mUnited Airlines
Deal found 2/19$742
This oojo deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2010:18 amSTL - GYE
2 stops21h 42mAvianca
Sun 3/163:30 amGYE - STL
2 stops30h 38mAvianca
Deal found 2/19$2,378
This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/57:00 amSTL - GYE
3 stops19h 05mMultiple Airlines
Sat 9/1312:55 pmGYE - STL
2 stops43h 11mMultiple Airlines
Deal found 2/19$7,408

Find flights from Missouri to Guayaquil within your budget

Customize your flight search to find flights from Missouri to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Missouri

Fly to

Guayaquil

Route

Depart

Return

Price

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Tue 4/15

4:20 pm-11:17 am

2 stops42h 57m

Guayaquil Jose Joaquin de Olmedo

Sat 5/31

2:45 pm-4:53 pm

2 stops26h 08m

$630

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Sun 4/27

5:37 am-8:53 pm

2 stops15h 16m

Guayaquil Jose Joaquin de Olmedo

Tue 5/6

6:00 am-9:31 pm

2 stops15h 31m

$640

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Tue 4/15

5:35 am-8:53 pm

1 stop15h 18m

Guayaquil Jose Joaquin de Olmedo

Sat 5/31

6:00 am-11:41 pm

2 stops17h 41m

$678

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Sun 4/27

4:35 pm-11:17 am

2 stops42h 42m

Guayaquil Jose Joaquin de Olmedo

Mon 5/5

3:15 am-6:39 pm

2 stops39h 24m

$742

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Fri 4/25

4:59 pm-5:34 pm

2 stops48h 35m

$164

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Wed 5/28

9:50 am-11:20 pm

2 stops13h 30m

$303

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Tue 4/29

7:45 am-11:39 pm

2 stops15h 54m

$322

St. LouisGuayaquil

STL - GYE

STLGYE

Lambert-St Louis

Sat 5/31

7:37 pm-1:45 pm

2 stops42h 08m

$333

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Tue 4/22

2:31 pm-2:15 pm

2 stops23h 44m

$339

Kansas CityGuayaquil

MCI - GYE

MCIGYE

Kansas City

Sun 4/27

5:45 am-6:53 am

2 stops25h 08m

$364

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 15 results
1
2

Best time to book a flight from Missouri to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Guayaquil

Get recent, data-driven insights about flights from Missouri to Guayaquil including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Guayaquil?

Currently, April is the cheapest month in which you can book a flight from Missouri to Guayaquil (average of $440). Flying from Missouri to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to GYE?

Find hourly flight availability from Missouri to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Guayaquil as you normally would.

Rainfall in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Guayaquil ranges from 0.0 - 11.0 inches per month. March is typically the wettest month, when rainfall can reach 11.0 in. July is typically the driest time to visit Guayaquil when rainfall is around 0.0 in.

Temperature in Guayaquil by month

Plan your trip to Guayaquil by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Guayaquil, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 77.0 F).

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated February 20, 2025.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines and United Airlines from Missouri to Guayaquil to help guide your decision. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,220 reviews
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,795 reviews
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,766 reviews
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,220 reviews

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Guayaquil from Missouri?

    Most people fly into Guayaquil Jose Joaquin de Olmedo (GYE) if they book a flight to Guayaquil from Missouri. Jose Joaquin de Olmedo is conveniently located just 2.5 mi from Guayaquil’s city center.

  • Can I find deals for flights from Missouri to Guayaquil that include hotel bookings?

    Yes. In addition to deals on Missouri to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Guayaquil.

  • Can I find deals for business class flights from Missouri to Guayaquil?

    Yes. Cheapflights offers flight deals from Missouri to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from Missouri to Guayaquil (average of $440). Flying from Missouri to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Guayaquil flights
Miami to Quito flights
John F Kennedy Intl to Quito flights
Newark to Guayaquil flights
LaGuardia to Guayaquil flights
Miami to Guayaquil flights
Newark to Quito flights
LaGuardia to Quito flights
O'Hare Intl to Quito flights
Fort Lauderdale to Guayaquil flights
San Francisco to Quito flights
John F Kennedy Intl to Cuenca flights
Los Angeles to Quito flights
Dallas/Fort Worth to Guayaquil flights
Dallas/Fort Worth to Quito flights
O'Hare Intl to Guayaquil flights
Dulles Intl to Quito flights
Orlando to Quito flights
Midway to Quito flights
Atlanta to Quito flights
Los Angeles to Guayaquil flights
Denver to Quito flights
Orlando to Guayaquil flights
Reagan-National to Quito flights
Austin to Quito flights
Baltimore to Quito flights
Seattle to Quito flights
Boston to Guayaquil flights
Boston to Quito flights
Fort Lauderdale to Quito flights
John F Kennedy Intl to Manta flights
LaGuardia to Cuenca flights
Newark to Cuenca flights
Seattle to Guayaquil flights
Sky Harbor Intl to Quito flights
Minneapolis to Quito flights
Charlotte to Guayaquil flights
Raleigh to Quito flights
Hobby to Quito flights
Dulles Intl to Guayaquil flights
Charlotte to Quito flights
San Jose to Quito flights
George Bush Intcntl to Quito flights
Indianapolis to Quito flights
Love Field to Quito flights
Jacksonville to Quito flights
Miami to Cuenca flights
Portland to Quito flights
Baltimore to Guayaquil flights
John F Kennedy Intl to Baltra flights

Top airline flying from Missouri to Guayaquil

Discover the top airline that operate flights from Missouri to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$483Average$619FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.