What are the cheapest airlines to fly from South Carolina to Guatemala one-way?

To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $106. Delta flights start at $152 while deals on American Airlines start at $153 one-way.

What is the cheapest month to fly from South Carolina to Guatemala?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, June can be a great choice for travel to Guatemala. Flights to Guatemala from South Carolina in June are about $467 on average during June, but can be found for as low as $270.

Can I find deals for flights from South Carolina to Guatemala that include hotel bookings?

Yes. In addition to deals on South Carolina to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Guatemala?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Guatemala.

Can I find deals for business class flights from South Carolina to Guatemala?

Yes. Cheapflights offers flight deals from South Carolina to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$440+ Flights from South Carolina to Guatemala

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Cheap flight deals from South Carolina to Guatemala

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$217 (eDestinos)
One-way from	$106 (Cheapflightsfares)
Popular in	December
Cheapest in	June

Provider with most accurate pricing for Myrtle Beach Intl-Guatemala City La Aurora flight deals.

Search Deals

Provider most trusted by Cheapflights users for Myrtle Beach Intl-Guatemala City La Aurora flights.

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From South Carolina to Guatemala

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One-way flight from South Carolina to Guatemala

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($104 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 12% potential price decrease ($51 potential savings vs. average RT price).

Search Deals

Find flight deals from South Carolina to Guatemala

Cheapest flights from South Carolina to Guatemala
Explore the most affordable flight options available from South Carolina to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

Wed 4/237:30 pmCHS - GUA

1 stop6h 34mSpirit Airlines

Tue 4/2912:59 amGUA - CHS

1 stop15h 36mSpirit Airlines

Deal found 4/1

$217

Mon 4/285:43 pmCLT - GUA

1 stop8h 21mSpirit Airlines

Wed 5/1412:59 amGUA - CLT

1 stop10h 59mSpirit Airlines

Deal found 4/1

$237

Sat 5/176:00 amMYR - GUA

1 stop6h 16mSpirit Airlines

Sat 5/2412:33 pmGUA - MYR

1 stop6h 32mSpirit Airlines

Deal found 4/1

$285

Fri 5/23:55 pmGSP - GUA

1 stop10h 09mMultiple Airlines

Sun 5/1112:59 amGUA - GSP

1 stop12h 06mMultiple Airlines

Deal found 4/1

$310

Thu 5/16:30 pmCLT - GUA

1 stop7h 34mMultiple Airlines

Thu 5/1512:33 pmGUA - CLT

2 stops16h 21mMultiple Airlines

Deal found 4/1

$314

Wed 10/18:48 pmCHS - GUA

2 stops16h 02mAmerican Airlines

Sun 10/51:10 pmGUA - CHS

2 stops18h 51mAmerican Airlines

Deal found 4/1

$359

Sat 5/176:02 pmMYR - GUA

3 stops19h 31mMultiple Airlines

Fri 5/2312:59 amGUA - MYR

2 stops31h 03mMultiple Airlines

Deal found 4/1

$435

Wed 4/96:00 amGSP - GUA

1 stop7h 40mAmerican Airlines

Wed 4/166:25 amGUA - GSP

2 stops15h 13mAmerican Airlines

Deal found 4/1

$439

Fri 5/1610:00 amSAV - GUA

2 stops27h 33mMultiple Airlines

Thu 5/2212:59 amGUA - SAV

2 stops29h 49mMultiple Airlines

Deal found 4/1

$447

Tue 7/157:00 amCHS - GUA

1 stop13h 49mUnited Airlines

Tue 7/2211:55 pmGUA - CHS

1 stop8h 19mUnited Airlines

Deal found 4/1

$480

Sun 7/279:50 pmCAE - GUA

1 stop15h 37mMultiple Airlines

Fri 8/11:28 amGUA - CAE

1 stop9h 53mMultiple Airlines

Deal found 4/1

$507

Sun 6/228:15 pmCLT - GUA

1 stop16h 39mAmerican Airlines

Tue 7/11:03 pmGUA - CLT

1 stop17h 22mAmerican Airlines

Deal found 4/1

$524

Best flights from South Carolina to Guatemala
Discover carefully curated flight deals from South Carolina to Guatemala that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2025.

Wed 4/237:30 pmCHS - GUA

1 stop6h 34mSpirit Airlines

Tue 4/2912:59 amGUA - CHS

1 stop15h 36mSpirit Airlines

Deal found 4/1

$217

Fri 5/23:55 pmGSP - GUA

1 stop10h 09mMultiple Airlines

Sun 5/1112:59 amGUA - GSP

1 stop12h 06mMultiple Airlines

Deal found 4/1

$310

Wed 4/166:40 amGSP - GUA

2 stops9h 05mAmerican Airlines

Mon 5/512:45 pmGUA - GSP

2 stops17h 48mAmerican Airlines

Deal found 4/1

$449

Mon 4/285:43 pmCLT - GUA

1 stop8h 21mSpirit Airlines

Wed 5/1412:59 amGUA - CLT

1 stop10h 59mSpirit Airlines

Deal found 4/1

$237

Tue 7/157:00 amCHS - GUA

1 stop13h 49mUnited Airlines

Tue 7/2211:55 pmGUA - CHS

1 stop8h 19mUnited Airlines

Deal found 4/1

$480

Mon 4/286:00 amCLT - GUA

3 stops17h 41mCopa Airlines

Fri 5/165:39 amGUA - CLT

3 stops26h 06mCopa Airlines

Deal found 4/1

$530

Fri 5/25:46 amGSP - GUA

1 stop7h 55mDelta

Fri 5/161:00 pmGUA - GSP

1 stop8h 52mDelta

Deal found 4/1

$540

Sat 5/176:00 amMYR - GUA

1 stop6h 16mSpirit Airlines

Sat 5/2412:33 pmGUA - MYR

1 stop6h 32mSpirit Airlines

Deal found 4/1

$285

Thu 5/16:30 pmCLT - GUA

1 stop7h 34mMultiple Airlines

Thu 5/1512:33 pmGUA - CLT

2 stops16h 21mMultiple Airlines

Deal found 4/1

$314

Tue 5/67:30 amCHS - GUA

1 stop6h 15mAmerican Airlines

Sun 5/112:40 pmGUA - CHS

1 stop17h 12mAmerican Airlines

Deal found 4/1

$468

Sat 5/176:02 pmMYR - GUA

3 stops19h 31mMultiple Airlines

Fri 5/2312:59 amGUA - MYR

2 stops31h 03mMultiple Airlines

Deal found 4/1

$435

Thu 5/17:00 amGSP - GUA

1 stop13h 49mUnited Airlines

Mon 5/121:30 amGUA - GSP

1 stop12h 00mUnited Airlines

Deal found 4/1

$525

Last-minute flights from South Carolina to Guatemala
Discover last-minute flight deals from South Carolina to Guatemala. Data last updated April 2, 2025 and is based on user searches.

Mon 4/712:30 pmCHS - GUA

1 stop11h 23mJetBlue

Mon 4/711:53 pmGUA - CHS

1 stop9h 52mJetBlue

Deal found 4/1

$900

Wed 4/96:00 amGSP - GUA

1 stop7h 40mAmerican Airlines

Wed 4/166:25 amGUA - GSP

2 stops15h 13mAmerican Airlines

Deal found 4/1

$439

Wed 4/97:05 amGSP - GUA

1 stop6h 31mUnited Airlines

Sat 4/121:30 amGUA - GSP

1 stop19h 59mUnited Airlines

Deal found 4/1

$754

Sat 4/1210:01 pmCLT - GUA

2 stops26h 47mMultiple Airlines

Thu 4/2412:36 pmGUA - CLT

1 stop9h 51mMultiple Airlines

Deal found 4/1

$383

Sat 4/125:43 pmCLT - GUA

1 stop8h 21mSpirit Airlines

Thu 4/2412:36 pmGUA - CLT

1 stop9h 51mSpirit Airlines

Deal found 4/1

$388

Sat 4/126:00 amCLT - GUA

2 stops29h 20mCopa Airlines

Thu 4/241:12 pmGUA - CLT

2 stops18h 34mCopa Airlines

Deal found 4/1

$934

Wed 4/237:30 pmCHS - GUA

1 stop6h 34mSpirit Airlines

Tue 4/2912:59 amGUA - CHS

1 stop15h 36mSpirit Airlines

Deal found 4/1

$217

Mon 4/285:43 pmCLT - GUA

1 stop8h 21mSpirit Airlines

Wed 5/1412:59 amGUA - CLT

1 stop10h 59mSpirit Airlines

Deal found 4/1

$237

Mon 4/286:00 amCLT - GUA

2 stops18h 48mCopa Airlines

Fri 5/167:09 amGUA - CLT

2 stops24h 36mCopa Airlines

Deal found 4/1

$530

Thu 5/16:30 pmCLT - GUA

1 stop7h 34mMultiple Airlines

Thu 5/1512:33 pmGUA - CLT

2 stops16h 21mMultiple Airlines

Deal found 4/1

$314

Thu 5/17:00 amGSP - GUA

1 stop9h 20mUnited Airlines

Tue 5/131:30 amGUA - GSP

1 stop12h 00mUnited Airlines

Deal found 4/1

$525

Fri 5/23:55 pmGSP - GUA

1 stop10h 09mMultiple Airlines

Sun 5/1112:59 amGUA - GSP

1 stop12h 06mMultiple Airlines

Deal found 4/1

$310

One-way flights from South Carolina to Guatemala
Search for one-way flight options from South Carolina to Guatemala. Find affordable one-way fares based on user searches. Data last updated April 2, 2025.

Sat 4/266:58 amCLT - GUA

1 stop6h 36mSpirit Airlines

Deal found 4/1

$106

Thu 5/86:00 amCLT - GUA

2 stops19h 10mMultiple Airlines

Deal found 4/1

$127

Tue 5/65:35 amCHS - GUA

1 stop8h 06mDelta

Deal found 4/1

$152

Tue 5/65:07 amCHS - GUA

2 stops10h 33mAmerican Airlines

Deal found 4/1

$153

Tue 4/2212:08 pmMYR - GUA

1 stop25h 26mSpirit Airlines

Deal found 4/1

$160

Tue 4/811:02 amCHS - GUA

1 stop14h 57mSpirit Airlines

Deal found 4/1

$174

Fri 9/197:26 pmGSP - GUA

2 stops18h 01mMultiple Airlines

Deal found 4/1

$189

Tue 4/82:15 pmCHS - GUA

2 stops20h 40mMultiple Airlines

Deal found 4/1

$191

Thu 6/58:15 amSAV - GUA

2 stops29h 18mMultiple Airlines

Deal found 3/31

$223

Wed 4/235:28 amGSP - GUA

2 stops10h 17mAmerican Airlines

Deal found 4/1

$238

Tue 5/66:00 amCHS - GUA

3 stops17h 41mCopa Airlines

Deal found 4/1

$252

Sun 4/2711:03 amCLT - GUA

2 stops9h 27mAmerican Airlines

Deal found 3/31

$255

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Guatemala that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Wed 4/23

7:30 pm-12:04 am

1 stop6h 34m

Guatemala City La Aurora

Tue 4/29

12:59 am-6:35 pm

1 stop15h 36m

$217

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Mon 4/28

5:43 pm-12:04 am

1 stop8h 21m

Guatemala City La Aurora

Wed 5/14

12:59 am-1:58 pm

1 stop10h 59m

$237

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Sat 5/17

6:00 am-10:16 am

1 stop6h 16m

Guatemala City La Aurora

Sat 5/24

12:33 pm-9:05 pm

1 stop6h 32m

$285

GreenvilleGuatemala City

GSP - GUA

GSPGUA

Greenville

Fri 5/2

3:55 pm-12:04 am

1 stop10h 09m

Guatemala City La Aurora

Sun 5/11

12:59 am-3:05 pm

1 stop12h 06m

$310

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Thu 5/1

6:30 pm-12:04 am

1 stop7h 34m

Guatemala City La Aurora

Thu 5/15

12:33 pm-6:54 am

2 stops16h 21m

$314

Myrtle BeachGuatemala City

MYR - GUA

MYRGUA

Myrtle Beach Intl

Sat 5/17

6:02 pm-11:33 am

3 stops19h 31m

Guatemala City La Aurora

Fri 5/23

12:59 am-10:02 am

2 stops31h 03m

$435

SavannahGuatemala City

SAV - GUA

SAVGUA

Savannah/Hilton Head

Fri 5/16

10:00 am-11:33 am

2 stops27h 33m

Guatemala City La Aurora

Thu 5/22

12:59 am-8:48 am

2 stops29h 49m

$447

GreenvilleGuatemala City

GSP - GUA

GSPGUA

Greenville

Wed 4/16

6:40 am-1:45 pm

2 stops9h 05m

Guatemala City La Aurora

Mon 5/5

12:45 pm-8:33 am

2 stops17h 48m

$449

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Tue 7/15

7:00 am-6:49 pm

1 stop13h 49m

Guatemala City La Aurora

Tue 7/22

11:55 pm-10:14 am

1 stop8h 19m

$480

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Tue 7/15

8:51 pm-10:44 am

1 stop15h 53m

Guatemala City La Aurora

Mon 7/21

12:40 am-2:08 pm

1 stop11h 28m

$501

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 49 results

...

Best time to book a flight from South Carolina to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Guatemala

What is the cheapest month to book a flight from South Carolina to Guatemala?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Guatemala (average of $291). Flying from South Carolina to Guatemala in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to GT?

When flying from South Carolina to Guatemala, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Guatemala

See what other customers who have flown with Delta, Copa Airlines and United Airlines from South Carolina to Guatemala have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,898 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.6

Good

1,400 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,615 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Spirit Airlines

6.3

Okay

7,886 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines to fly from South Carolina to Guatemala one-way?
To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $106. Delta flights start at $152 while deals on American Airlines start at $153 one-way.
Can I find deals for flights from South Carolina to Guatemala that include hotel bookings?
Yes. In addition to deals on South Carolina to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Guatemala?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Guatemala.
Can I find deals for business class flights from South Carolina to Guatemala?
Yes. Cheapflights offers flight deals from South Carolina to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South Carolina to Guatemala?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Guatemala (average of $291). Flying from South Carolina to Guatemala in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for South Carolina to Guatemala

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Reagan-National to San José flights

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Atlanta to San Salvador flights

Top 4 airlines flying from South Carolina to Guatemala

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$274	Average$592	FlexibilityNo cancel fee	On-timeN/A
Spirit Airlines	Cheapest$300	Average$365	FlexibilityNo cancel fee	On-time65%
American Airlines	Cheapest$349	Average$682	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$482	Average$729	FlexibilityNo cancel fee	On-time69%

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$106+ Cheap flights from South Carolina to Guatemala

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from South Carolina to Guatemala

Keep the following information in mind while searching for South Carolina to Guatemala flight deals. Data was last updated April 2, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Find flight deals from South Carolina to Guatemala

Cheapest flights from South Carolina to GuatemalaExplore the most affordable flight options available from South Carolina to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

Explore the most affordable flight options available from South Carolina to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Guatemala that are best for you.

Best time to book a flight from South Carolina to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Guatemala

What is the cheapest month to book a flight from South Carolina to Guatemala?

What is the cheapest time of day to fly from SC to GT?

Find hourly flight availability from South Carolina to Guatemala. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

Reviews of airlines servicing Guatemala

See what other customers who have flown with Delta, Copa Airlines and United Airlines from South Carolina to Guatemala have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines to fly from South Carolina to Guatemala one-way?

Can I find deals for flights from South Carolina to Guatemala that include hotel bookings?

How can I find direct flights from South Carolina to Guatemala?

Can I find deals for business class flights from South Carolina to Guatemala?

What is the cheapest month to book a flight from South Carolina to Guatemala?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Guatemala

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from South Carolina to Guatemala

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Travel Smart

Cheapest flights from South Carolina to Guatemala
Explore the most affordable flight options available from South Carolina to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.