HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Guatemala

$84+ Cheap flights from South Carolina to Guatemala

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GUA
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Guatemala with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Guatemala

Keep the following information in mind while searching for South Carolina to Guatemala flight deals. Data was last updated April 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$209
(Cheapflightsfares)

One-way from

$84
(Cheapflightsfares)

Popular in

December

Cheapest in

June
Provider with most accurate pricing for Myrtle Beach Intl-Guatemala City La Aurora flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Guatemala City La Aurora flights.
Search Deals
From South Carolina to Guatemala
Search Deals
One-way flight from South Carolina to Guatemala
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($111 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 12% potential price decrease ($52 potential savings vs. average RT price).
Search Deals

Find flight deals from South Carolina to Guatemala

Cheapest flights from South Carolina to Guatemala
Explore the most affordable flight options available from South Carolina to Guatemala. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/104:46 pmCLT - GUA
1 stop9h 08mSpirit Airlines
Sat 5/1712:33 pmGUA - CLT
1 stop7h 27mSpirit Airlines
Deal found 4/17$209
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:50 amCLT - GUA
1 stop6h 37mMultiple Airlines
Sat 11/18:25 amGUA - CLT
2 stops13h 03mMultiple Airlines
Deal found 4/17$283
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/910:26 amCHS - GUA
1 stop11h 24mAmerican Airlines
Thu 7/176:00 amGUA - CHS
1 stop10h 48mAmerican Airlines
Deal found 4/17$350
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/14:33 pmGSP - GUA
2 stops21h 01mMultiple Airlines
Thu 5/812:33 pmGUA - GSP
1 stop24h 32mMultiple Airlines
Deal found 4/17$405
This CheapOair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/199:02 amCLT - GUA
1 stop9h 36mFrontier
Thu 7/35:58 pmGUA - CLT
2 stops46h 20mFrontier
Deal found 4/17$480
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/47:00 amCLT - GUA
1 stop6h 41mDelta
Thu 8/141:05 pmGUA - CLT
1 stop7h 20mDelta
Deal found 4/17$512
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:40 amCAE - GUA
1 stop8h 17mDelta
Mon 9/221:28 pmGUA - CAE
1 stop8h 26mDelta
Deal found 4/17$512
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:40 amCAE - GUA
1 stop11h 19mAmerican Airlines
Mon 9/221:10 pmGUA - CAE
2 stops19h 05mAmerican Airlines
Deal found 4/17$516
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/145:54 amGSP - GUA
1 stop9h 46mAmerican Airlines
Fri 6/61:03 pmGUA - GSP
1 stop8h 54mAmerican Airlines
Deal found 4/17$528
This Copa Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/286:00 amCLT - GUA
2 stops29h 20mCopa Airlines
Fri 5/165:39 amGUA - CLT
3 stops26h 06mCopa Airlines
Deal found 4/17$535
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/16:30 pmAGS - GUA
2 stops19h 15mAmerican Airlines
Sun 6/811:58 amGUA - AGS
2 stops18h 39mAmerican Airlines
Deal found 4/17$545
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:15 amCLT - GUA
1 stop9h 35mAmerican Airlines
Mon 10/272:40 pmGUA - CLT
1 stop15h 30mAmerican Airlines
Deal found 4/17$545

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from South Carolina to Guatemala that are best for you.

Fly from

South Carolina

Fly to

Guatemala

Route

Depart

Return

Price

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Sat 5/10

4:46 pm-11:54 pm

1 stop9h 08m

Guatemala City La Aurora

Sat 5/17

12:33 pm-10:00 pm

1 stop7h 27m

$209

CharlestonGuatemala City

CHS - GUA

CHSGUA

Charleston

Wed 7/9

10:26 am-7:50 pm

1 stop11h 24m

Guatemala City La Aurora

Thu 7/17

6:00 am-6:48 pm

1 stop10h 48m

$350

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Thu 7/3

9:02 am-4:38 pm

1 stop9h 36m

Guatemala City La Aurora

Tue 7/15

1:28 am-4:55 pm

1 stop13h 27m

$372

GreenvilleGuatemala City

GSP - GUA

GSPGUA

Greenville

Thu 5/1

4:33 pm-11:34 am

2 stops21h 01m

Guatemala City La Aurora

Thu 5/8

12:33 pm-3:05 pm

1 stop24h 32m

$405

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Thu 6/19

9:02 am-4:38 pm

1 stop9h 36m

Guatemala City La Aurora

Thu 7/3

5:58 pm-6:18 pm

2 stops46h 20m

$480

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Mon 8/4

7:00 am-11:41 am

1 stop6h 41m

Guatemala City La Aurora

Thu 8/14

1:05 pm-10:25 pm

1 stop7h 20m

$512

ColumbiaGuatemala City

CAE - GUA

CAEGUA

Columbia Metropolitan

Thu 9/18

5:40 am-11:57 am

1 stop8h 17m

Guatemala City La Aurora

Mon 9/22

1:28 pm-11:54 pm

1 stop8h 26m

$512

ColumbiaGuatemala City

CAE - GUA

CAEGUA

Columbia Metropolitan

Thu 9/18

7:40 am-4:59 pm

1 stop11h 19m

Guatemala City La Aurora

Mon 9/22

1:10 pm-10:15 am

2 stops19h 05m

$516

GreenvilleGuatemala City

GSP - GUA

GSPGUA

Greenville

Wed 5/14

5:54 am-6:52 pm

1 stop14h 58m

Guatemala City La Aurora

Thu 6/5

12:35 am-7:35 pm

1 stop17h 00m

$528

CharlotteGuatemala City

CLT - GUA

CLTGUA

Charlotte Douglas

Mon 4/28

6:00 am-9:20 am

2 stops29h 20m

Guatemala City La Aurora

Fri 5/16

5:39 am-9:45 am

3 stops26h 06m

$535

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 36 results
1
2
3
4

Best time to book a flight from South Carolina to Guatemala

Have a flexible travel schedule? Discover the best time to fly to Guatemala from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Guatemala

What is the cheapest month to book a flight from South Carolina to Guatemala?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Guatemala (average of $291). Flying from South Carolina to Guatemala in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to GT?

Find hourly flight availability from South Carolina to Guatemala. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from South Carolina to Guatemala, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Guatemala

Get insights into the airlines that provide service to Guatemala. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guatemala. Reviews last updated April 17, 2025.
See what other customers who have flown with Delta, Copa Airlines and United Airlines from South Carolina to Guatemala have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,409 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Air Canada
7.0
Good
9,143 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Guatemala. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Guatemala one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $84. Frontier flights start at $167 while deals on Delta start at $207 one-way.

  • Can I find deals for flights from South Carolina to Guatemala that include hotel bookings?

    Yes. In addition to deals on South Carolina to Guatemala flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Guatemala?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Guatemala.

  • Can I find deals for business class flights from South Carolina to Guatemala?

    Yes. Cheapflights offers flight deals from South Carolina to Guatemala by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Guatemala?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Guatemala (average of $291). Flying from South Carolina to Guatemala in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Guatemala

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to San José flights
John F Kennedy Intl to Panama City flights
Newark to San José flights
Los Angeles to San José flights
Los Angeles to San Salvador flights
Los Angeles to Guatemala City flights
Dulles Intl to San Salvador flights
Hobby to San Salvador flights
Newark to Panama City flights
Dallas/Fort Worth to San Salvador flights
John F Kennedy Intl to Guatemala City flights
John F Kennedy Intl to San Salvador flights
Newark to Liberia flights
John F Kennedy Intl to Liberia flights
George Bush Intcntl to San Salvador flights
LaGuardia to San José flights
Dulles Intl to Panama City flights
San Francisco to San José flights
Miami to Panama City flights
Dulles Intl to Guatemala City flights
Newark to Guatemala City flights
Los Angeles to Liberia flights
Los Angeles to Panama City flights
Ontario to San Salvador flights
Miami to San José flights
Fort Lauderdale to San José flights
Boston to San José flights
Atlanta to San José flights
Reagan-National to San Salvador flights
Baltimore to San Salvador flights
Hobby to San José flights
Orlando to San José flights
Orlando to Panama City flights
Dulles Intl to San José flights
Hobby to Guatemala City flights
LaGuardia to Panama City flights
Newark to San Salvador flights
LaGuardia to Liberia flights
Miami to Managua flights
Dallas/Fort Worth to San José flights
George Bush Intcntl to San José flights
Newark to Philip S.W.Goldson flights
George Bush Intcntl to Guatemala City flights
Dallas/Fort Worth to Panama City flights
Atlanta to Guatemala City flights
Atlanta to Panama City flights
Boston to Panama City flights
Ontario to Guatemala City flights
Los Angeles to Philip S.W.Goldson flights
LaGuardia to Guatemala City flights

Top 4 airlines flying from South Carolina to Guatemala

Discover the top 4 airlines that operate flights from South Carolina to Guatemala. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$274Average$624FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$300Average$355FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$349Average$595FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$349Average$652FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.