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$280+ Cheap flights from Panama City (PTY) to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — GSP
Mar 10 — Mar 171
Mon 3/10
Mon 3/17
1 adult, Economy
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Cheap flight deals from Panama City to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 5, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$417
(Delta)

One-way from

$280
(Delta)
Provider with most accurate pricing for Panama City Tocumen Intl-Greenville flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Greenville flights.
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From Panama City Tocumen Intl to Greenville
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One-way flight from Panama City Tocumen Intl to Greenville
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Find flight deals from Panama City to Greenville

Cheapest flights from Panama City to Greenville
Explore the most affordable flight options available from Panama City to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2025.

This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/32:23 pmPTY - GSP
1 stop8h 15mDelta
Tue 4/88:03 amGSP - PTY
1 stop5h 55mDelta
Deal found 3/4$417
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/123:30 pmPTY - GSP
1 stop7h 27mAmerican Airlines
Mon 3/178:38 pmGSP - PTY
2 stops16h 37mAmerican Airlines
Deal found 3/5$430
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/127:55 amPTY - GSP
1 stop14h 20mUnited Airlines
Mon 3/177:04 amGSP - PTY
1 stop10h 03mUnited Airlines
Deal found 3/5$436
This Avianca deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/113:19 amPTY - GSP
2 stops16h 27mAvianca
Mon 3/176:40 amGSP - PTY
2 stops18h 40mAvianca
Deal found 3/5$3,763

Find flights from Panama City to Greenville within your budget

Customize your flight search to find flights from Panama City to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2025.

Fly from

Panama City

Fly to

Greenville

Route

Depart

Return

Price

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 4/3

2:23 pm-11:38 pm

1 stop8h 15m

Greenville

Tue 4/8

8:03 am-12:58 pm

1 stop5h 55m

$417

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Wed 3/12

3:30 pm-11:57 pm

1 stop7h 27m

Greenville

Mon 3/17

8:38 pm-12:15 pm

2 stops16h 37m

$430

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Wed 3/12

7:55 am-11:15 pm

1 stop14h 20m

Greenville

Mon 3/17

7:04 am-4:07 pm

1 stop10h 03m

$436

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Tue 3/11

3:19 am-8:46 pm

2 stops16h 27m

Greenville

Mon 3/17

6:40 am-12:20 am

2 stops18h 40m

$3,763

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Fri 4/25

2:20 pm-11:53 pm

1 stop8h 33m

$280

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Fri 4/25

1:15 pm-11:37 am

2 stops21h 22m

$348

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 4/24

3:20 am-8:28 pm

3 stops16h 08m

$362

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Fri 4/25

10:00 am-11:29 pm

1 stop12h 29m

$699

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/4

Compare providers for flights from Panama City to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Greenville in March.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to Greenville

Get recent, data-driven insights about flights from Panama City to Greenville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City to Greenville?

Currently, January is the cheapest month in which you can book a flight from Panama City to Greenville (average of $329). Flying from Panama City to Greenville in March is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to GSP?

Find hourly flight availability from Panama City to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 5, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Greenville as you normally would.

Rainfall in Greenville by month

Plan your trip to Greenville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

Temperature in Greenville by month

Plan your trip to Greenville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated March 5, 2025.
Delta
8.0
Very good
8,044 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,044 reviews
Delta
8.0
Very good
8,044 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,655 reviews
Delta
8.0
Very good
8,044 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,044 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Comfort

8.0

Overall

8.0

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to Greenville round-trip?

    Our cheapest airline available from Panama City to Greenville is Delta. Our recent data shows that you can find tickets from as low as $417 on this airline. An additional option worth looking into is American Airlines, starting at $443.

  • What are the cheapest airlines to fly from Panama City to Greenville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $280. American Airlines flights start at $348 while deals on United Airlines start at $699 one-way.

  • Can I find deals for flights from Panama City to Greenville that include hotel bookings?

    Yes. In addition to deals on Panama City to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Greenville.

  • Can I find deals for business class flights from Panama City to Greenville?

    Yes. Cheapflights offers flight deals from Panama City to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Greenville (average of $329). Flying from Panama City to Greenville in March is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Simpsonville
Seneca
Anderson

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