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Greenville

$167+ Cheap flights from Missouri to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Missouri to Greenville

Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$272
(Delta)

One-way from

$167
(American Airlines)

Popular in

January

Cheapest in

September

Average price

$561
Provider with most accurate pricing for Kansas City-Greenville flight deals.
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Provider most trusted by Cheapflights users for Kansas City-Greenville flights.
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From Missouri to Greenville
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One-way flight from Missouri to Greenville
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Highest demand for flights based on searches. 13% potential increase in price ($67 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Missouri to Greenville

Cheapest flights from Missouri to Greenville
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/116:33 pmMCI - GSP
1 stop4h 13mAmerican Airlines
Tue 5/206:00 amGSP - MCI
1 stop5h 23mAmerican Airlines
Deal found 4/16$271
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:45 pmSTL - GSP
1 stop4h 21mDelta
Thu 5/225:25 amGSP - STL
1 stop4h 35mDelta
Deal found 4/17$272
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/175:45 amMCI - GSP
1 stop3h 51mDelta
Sat 5/245:30 amGSP - MCI
1 stop4h 55mDelta
Deal found 4/16$284
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/97:25 amMCI - GSP
1 stop6h 10mSouthwest
Sat 7/263:25 pmGSP - MCI
1 stop7h 55mSouthwest
Deal found 4/16$297
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/206:00 amSTL - GSP
1 stop8h 05mSouthwest
Thu 5/226:50 amGSP - STL
2 stops9h 10mSouthwest
Deal found 4/17$312
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/185:12 amSTL - GSP
1 stop4h 32mAmerican Airlines
Sat 6/146:26 pmGSP - STL
1 stop6h 28mAmerican Airlines
Deal found 4/17$317
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/98:00 amMCI - GSP
2 stops8h 03mUnited Airlines
Sat 7/264:25 pmGSP - MCI
1 stop8h 06mUnited Airlines
Deal found 4/16$328
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:56 pmSGF - GSP
1 stop3h 56mDelta
Sun 6/15:30 amGSP - SGF
1 stop6h 50mDelta
Deal found 4/16$338
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/810:10 amSTL - GSP
1 stop27h 55mMultiple Airlines
Sun 5/112:37 pmGSP - STL
3 stops29h 04mMultiple Airlines
Deal found 4/16$379
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/226:43 pmMCI - GSP
2 stops25h 09mMultiple Airlines
Mon 7/284:05 pmGSP - MCI
2 stops26h 33mMultiple Airlines
Deal found 4/17$388
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/46:35 amSTL - GSP
2 stops9h 30mUnited Airlines
Sun 9/76:03 amGSP - STL
1 stop5h 35mUnited Airlines
Deal found 4/17$392
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:15 amSGF - GSP
2 stops7h 31mAmerican Airlines
Sun 6/16:26 amGSP - SGF
1 stop5h 25mAmerican Airlines
Deal found 4/16$573

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.

Fly from

Missouri

Fly to

Greenville

Route

Depart

Return

Price

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Sun 5/11

6:33 pm-11:46 pm

1 stop4h 13m

Greenville

Tue 5/20

6:00 am-10:23 am

1 stop5h 23m

$271

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 5/20

5:45 pm-11:06 pm

1 stop4h 21m

Greenville

Thu 5/22

5:25 am-9:00 am

1 stop4h 35m

$272

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Sat 5/17

5:45 am-10:36 am

1 stop3h 51m

Greenville

Sat 5/24

5:30 am-9:25 am

1 stop4h 55m

$284

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Wed 7/9

7:25 am-2:35 pm

1 stop6h 10m

Greenville

Sat 7/26

3:25 pm-10:20 pm

1 stop7h 55m

$297

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 5/20

6:00 am-3:05 pm

1 stop8h 05m

Greenville

Thu 5/22

6:50 am-3:00 pm

2 stops9h 10m

$312

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sun 5/18

5:12 am-10:44 am

1 stop4h 32m

Greenville

Sat 6/14

6:26 pm-11:54 pm

1 stop6h 28m

$317

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Wed 7/9

8:00 am-5:03 pm

2 stops8h 03m

Greenville

Sat 7/26

4:25 pm-11:31 pm

1 stop8h 06m

$328

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Wed 5/28

6:56 pm-11:52 pm

1 stop3h 56m

Greenville

Sun 6/1

5:30 am-11:20 am

1 stop6h 50m

$338

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 5/8

10:10 am-3:05 pm

1 stop27h 55m

Greenville

Sun 5/11

2:37 pm-6:41 pm

3 stops29h 04m

$379

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 9/4

6:35 am-5:05 pm

2 stops9h 30m

Greenville

Sun 9/7

6:03 am-10:38 am

1 stop5h 35m

$392

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 23 results
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Best time to book a flight from Missouri to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Greenville

What is the cheapest month to book a flight from Missouri to Greenville?

Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $329). Flying from Missouri to Greenville in March is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to GSP?

Find hourly flight availability from Missouri to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Greenville as you normally would.

Rainfall in Greenville by month

Plan your trip to Greenville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

Temperature in Greenville by month

Plan your trip to Greenville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated April 17, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Missouri to Greenville to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,280 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,917 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,667 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Allegiant Air
7.3
Good
734 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,280 reviews

Boarding

8.2

Overall

8.0

Food

7.1

Crew

8.6

Comfort

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Missouri?

    Most people fly into Greenville (GSP) if they book a flight to Greenville from Missouri. Greenville is conveniently located just 10.4 mi from Greenville’s city center.

  • What are the cheapest airlines to fly from Missouri to Greenville one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $167. Southwest flights start at $192 while deals on Allegiant Air start at $195 one-way.

  • What are the most popular routes from Missouri to Greenville?

    The most popular flight routes from Missouri to Greenville are Lambert-St Louis - Greenville, Kansas City - Greenville and Springfield-Branson - Greenville.

  • Can I find deals for flights from Missouri to Greenville that include hotel bookings?

    Yes. In addition to deals on Missouri to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Greenville.

  • Can I find deals for business class flights from Missouri to Greenville?

    Yes. Cheapflights offers flight deals from Missouri to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $329). Flying from Missouri to Greenville in March is currently the most expensive (average of $384). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Simpsonville
Seneca
Duncan
Anderson

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Top 4 airlines flying from Missouri to Greenville

Discover the top 4 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$223Average$399FlexibilityNo cancel feeOn-time69%
DeltaCheapest$245Average$363FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$271Average$404FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$346Average$396FlexibilityNo cancel feeOn-time63%

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