Greenville

$144+ Cheap flights from Missouri to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Jan 26 — Feb 21
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Greenville with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Missouri (USMO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$287
(Delta)

One-way from

$144
(Delta)
From Missouri to Greenville
One-way flight from Missouri to Greenville

Find flight deals from Missouri to Greenville

Cheapest flights from Missouri to Greenville
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2510:30 amSTL - GSP
1 stop6h 03mDelta
Tue 4/15:13 pmGSP - STL
1 stop5h 27mDelta
Deal found 1/20$287
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/48:25 amSTL - GSP
1 stop4h 51mUnited Airlines
Tue 3/116:00 amGSP - STL
2 stops7h 12mUnited Airlines
Deal found 1/20$292
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/85:35 amMCI - GSP
1 stop4h 03mDelta
Sat 2/83:14 pmGSP - MCI
1 stop4h 04mDelta
Deal found 1/20$297
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/810:41 amMCI - GSP
2 stops7h 23mAmerican Airlines
Sat 2/158:10 amGSP - MCI
1 stop4h 27mAmerican Airlines
Deal found 1/20$302
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/25:33 amSGF - GSP
1 stop5h 27mAmerican Airlines
Fri 4/44:19 pmGSP - SGF
1 stop6h 45mAmerican Airlines
Deal found 1/21$319
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:55 amSTL - GSP
1 stop5h 07mAmerican Airlines
Fri 3/148:38 pmGSP - STL
1 stop4h 18mAmerican Airlines
Deal found 1/21$350
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/215:20 amSTL - GSP
1 stop5h 05mSouthwest
Sun 2/237:05 amGSP - STL
2 stops7h 10mSouthwest
Deal found 1/19$352
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/28:00 amSGF - GSP
2 stops10h 09mUnited Airlines
Fri 4/46:30 amGSP - SGF
1 stop5h 13mUnited Airlines
Deal found 1/21$361
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/89:55 amMCI - GSP
2 stops11h 43mUnited Airlines
Tue 2/112:55 pmGSP - MCI
1 stop6h 31mUnited Airlines
Deal found 1/20$372
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/298:50 amMCI - GSP
2 stops8h 40mSouthwest
Sat 4/510:15 amGSP - MCI
2 stops11h 20mSouthwest
Deal found 1/20$387
This Mytrip deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/165:15 pmSTL - GSP
3 stops19h 26mMultiple Airlines
Sun 3/29:51 pmGSP - STL
3 stops21h 50mMultiple Airlines
Deal found 1/21$554
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1311:52 amMCI - GSP
2 stops26h 13mMultiple Airlines
Thu 3/205:04 pmGSP - MCI
3 stops45h 43mMultiple Airlines
Deal found 1/20$666

Find flights from Missouri to Greenville within your budget

Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 3/25

10:30 am-5:33 pm

1 stop6h 03m

Greenville

Tue 4/1

5:13 pm-9:40 pm

1 stop5h 27m

$287

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 3/4

8:25 am-2:16 pm

1 stop4h 51m

Greenville

Tue 3/11

6:00 am-12:12 pm

2 stops7h 12m

$292

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Sat 2/8

7:00 am-2:19 pm

1 stop6h 19m

Greenville

Sat 2/15

5:40 am-11:15 am

1 stop6h 35m

$297

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Sat 2/8

10:41 am-7:04 pm

2 stops7h 23m

Greenville

Sat 2/15

8:10 am-11:37 am

1 stop4h 27m

$302

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Wed 4/2

5:33 am-12:00 pm

1 stop5h 27m

Greenville

Fri 4/4

4:19 pm-10:04 pm

1 stop6h 45m

$319

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Fri 3/7

5:55 am-12:02 pm

1 stop5h 07m

Greenville

Fri 3/14

8:38 pm-11:56 pm

1 stop4h 18m

$350

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Fri 2/21

5:20 am-11:25 am

1 stop5h 05m

Greenville

Sun 2/23

7:05 am-1:15 pm

2 stops7h 10m

$352

SpringfieldGreenville

SGF - GSP

SGFGSP

Springfield-Branson

Wed 4/2

8:00 am-7:09 pm

2 stops10h 09m

Greenville

Fri 4/4

6:30 am-10:43 am

1 stop5h 13m

$361

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Sat 2/8

9:55 am-10:38 pm

2 stops11h 43m

Greenville

Tue 2/11

2:55 pm-8:26 pm

1 stop6h 31m

$372

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Sat 3/29

8:50 am-6:30 pm

2 stops8h 40m

Greenville

Sat 4/5

10:15 am-8:35 pm

2 stops11h 20m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 16 results
1
2

Best time to book a flight from Missouri to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Greenville

Get recent, data-driven insights about flights from Missouri to Greenville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Greenville?

Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $329). Flying from Missouri to Greenville in March is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to GSP?

Find hourly flight availability from Missouri to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Greenville as you normally would.

Rainfall in Greenville by month

Plan your trip to Greenville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

Temperature in Greenville by month

Plan your trip to Greenville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 21, 2025.
Peruse reviews from past customers who have flown with Delta, Southwest and American Airlines from Missouri to Greenville to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.1
Very good
4,662 reviews

Crew

8.7

Comfort

8.1

Boarding

8.2

Overall

8.1

Food

7.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.1
Very good
4,662 reviews
8.1
Very good
4,662 reviews

Crew

8.7

Comfort

8.1

Boarding

8.2

Overall

8.1

Food

7.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

8.0
Very good
8,521 reviews
8.1
Very good
4,662 reviews

Crew

8.7

Comfort

8.1

Boarding

8.2

Overall

8.1

Food

7.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.4
Good
8,985 reviews
8.1
Very good
4,662 reviews

Crew

8.7

Comfort

8.1

Boarding

8.2

Overall

8.1

Food

7.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

7.2
Good
10,000 reviews
8.1
Very good
4,662 reviews

Crew

8.7

Comfort

8.1

Boarding

8.2

Overall

8.1

Food

7.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Greenville from Missouri?

    Most people fly into Greenville (GSP) if they book a flight to Greenville from Missouri. Greenville is conveniently located just 10.4 mi from Greenville’s city center.

  • What are the cheapest airlines to fly from Missouri to Greenville one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $144. Southwest flights start at $154 while deals on American Airlines start at $184 one-way.

  • What are the most popular routes from Missouri to Greenville?

  • Can I find deals for flights from Missouri to Greenville that include hotel bookings?

    Yes. In addition to deals on Missouri to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Greenville.

  • Can I find deals for business class flights from Missouri to Greenville?

    Yes. Cheapflights offers flight deals from Missouri to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $329). Flying from Missouri to Greenville in March is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Simpsonville
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Greenville

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Missouri to Greenville

Discover the top 4 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$245Average$361FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$441FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$303Average$399FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$346Average$396FlexibilityNo cancel feeOn-time63%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.