Greenville

$102+ Cheap flights from Missouri to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GSP
Feb 25 — Mar 41
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Cheap flight deals from Missouri to Greenville

Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated February 20, 2025.

Round-trip from

$212
(Mytrip)

One-way from

$102
(Mytrip)
From Missouri to Greenville
One-way flight from Missouri to Greenville

Find flight deals from Missouri to Greenville

Cheapest flights from Missouri to Greenville
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/65:12 pmMCI - GSP
1 stop21h 41mMultiple Airlines
Mon 3/104:35 pmGSP - MCI
1 stop17h 40mMultiple Airlines
Deal found 2/19$212
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/251:48 pmSTL - GSP
1 stop7h 07mDelta
Tue 4/15:47 amGSP - STL
1 stop4h 27mDelta
Deal found 2/19$287
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/317:00 amMCI - GSP
1 stop6h 10mDelta
Thu 4/35:46 amGSP - MCI
1 stop5h 01mDelta
Deal found 2/20$297
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/316:15 amMCI - GSP
1 stop3h 50mSouthwest
Thu 4/312:00 pmGSP - MCI
2 stops6h 55mSouthwest
Deal found 2/20$302
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/206:42 pmSGF - GSP
1 stop3h 59mAmerican Airlines
Thu 3/64:18 pmGSP - SGF
1 stop6h 40mAmerican Airlines
Deal found 2/20$304
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/81:51 pmSTL - GSP
1 stop4h 17mAmerican Airlines
Sat 3/158:38 pmGSP - STL
1 stop4h 18mAmerican Airlines
Deal found 2/19$307
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/203:20 pmSGF - GSP
1 stop4h 54mUnited Airlines
Thu 3/66:00 amGSP - SGF
2 stops9h 30mUnited Airlines
Deal found 2/20$310
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/169:36 amMCI - GSP
1 stop4h 55mAmerican Airlines
Mon 4/214:16 pmGSP - MCI
1 stop7h 40mAmerican Airlines
Deal found 2/19$332
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/311:45 pmSTL - GSP
2 stops7h 15mSouthwest
Thu 4/35:10 pmGSP - STL
1 stop4h 50mSouthwest
Deal found 2/18$342
This United deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2510:03 amSTL - GSP
1 stop5h 48mUnited Airlines
Tue 4/110:30 amGSP - STL
2 stops12h 18mUnited Airlines
Deal found 2/19$363
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/73:29 pmMCI - GSP
1 stop6h 08mUnited Airlines
Tue 4/810:30 amGSP - MCI
2 stops10h 19mUnited Airlines
Deal found 2/19$372
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/69:50 amSTL - GSP
3 stops34h 20mMultiple Airlines
Mon 3/103:55 pmGSP - STL
1 stop25h 47mMultiple Airlines
Deal found 2/19$385

Find flights from Missouri to Greenville within your budget

Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Missouri

Fly to

Greenville

Route

Depart

Return

Price

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Thu 3/6

5:12 pm-3:53 pm

1 stop21h 41m

Greenville

Mon 3/10

4:35 pm-9:15 am

1 stop17h 40m

$212

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 3/25

1:48 pm-9:55 pm

1 stop7h 07m

Greenville

Tue 4/1

5:47 am-9:14 am

1 stop4h 27m

$287

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Mon 3/31

6:15 am-11:05 am

1 stop3h 50m

Greenville

Wed 4/2

7:50 am-3:05 pm

1 stop8h 15m

$297

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Sat 3/8

1:51 pm-7:08 pm

1 stop4h 17m

Greenville

Sat 3/15

8:38 pm-11:56 pm

1 stop4h 18m

$307

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Fri 3/7

7:00 am-2:19 pm

1 stop6h 19m

Greenville

Mon 3/10

5:20 pm-9:44 pm

1 stop5h 24m

$317

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Wed 4/16

9:36 am-3:31 pm

1 stop4h 55m

Greenville

Mon 4/21

4:16 pm-10:56 pm

1 stop7h 40m

$332

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Mon 3/31

1:45 pm-10:00 pm

2 stops7h 15m

Greenville

Thu 4/3

5:10 pm-9:00 pm

1 stop4h 50m

$342

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Tue 3/25

10:03 am-4:51 pm

1 stop5h 48m

Greenville

Tue 4/1

10:30 am-9:48 pm

2 stops12h 18m

$363

Kansas CityGreenville

MCI - GSP

MCIGSP

Kansas City

Mon 4/7

3:29 pm-10:37 pm

1 stop6h 08m

Greenville

Tue 4/8

10:30 am-7:49 pm

2 stops10h 19m

$372

St. LouisGreenville

STL - GSP

STLGSP

Lambert-St Louis

Thu 3/6

9:50 am-9:10 pm

3 stops34h 20m

Greenville

Mon 3/10

3:55 pm-4:42 pm

1 stop25h 47m

$385

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 18 results
1
2

Best time to book a flight from Missouri to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Greenville

Get recent, data-driven insights about flights from Missouri to Greenville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Greenville?

Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $329). Flying from Missouri to Greenville in March is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to GSP?

Find hourly flight availability from Missouri to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Greenville as you normally would.

Rainfall in Greenville by month

Plan your trip to Greenville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

Temperature in Greenville by month

Plan your trip to Greenville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated February 20, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Missouri to Greenville to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

8.0
Very good

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Comfort

8.1

Entertainment

7.6

Food

7.1

Overall

8.1

Crew

8.7

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Greenville from Missouri?

    Most people fly into Greenville (GSP) if they book a flight to Greenville from Missouri. Greenville is conveniently located just 10.4 mi from Greenville’s city center.

  • What are the cheapest airlines to fly from Missouri to Greenville one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $169. Southwest flights start at $199 while deals on United Airlines start at $209 one-way.

  • What are the most popular routes from Missouri to Greenville?

  • Can I find deals for flights from Missouri to Greenville that include hotel bookings?

    Yes. In addition to deals on Missouri to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Greenville.

  • Can I find deals for business class flights from Missouri to Greenville?

    Yes. Cheapflights offers flight deals from Missouri to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville (average of $329). Flying from Missouri to Greenville in March is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Simpsonville
Seneca
Anderson

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Alternative routes for Missouri to Greenville

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Missouri to Greenville

Discover the top 4 airlines that operate flights from Missouri to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$245Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$271Average$403FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$303Average$399FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$346Average$396FlexibilityNo cancel feeOn-time63%
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