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$204+ Cheap flights from Iowa to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSP
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Iowa to Greenville

Keep the following information in mind while searching for Iowa to Greenville flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$259
(American Airlines)

One-way from

$204
(American Airlines)

Popular in

November

Cheapest in

January

Average price

$475
Provider with most accurate pricing for Des Moines-Greenville flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Greenville flights.
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From Iowa to Greenville
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One-way flight from Iowa to Greenville
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Highest demand for flights based on searches. 11% potential increase in price ($54 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Iowa to Greenville

Cheapest flights from Iowa to Greenville
Explore the most affordable flight options available from Iowa to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/63:25 pmMLI - GSP
1 stop6h 32mAmerican Airlines
Sat 3/86:31 pmGSP - MLI
1 stop4h 33mAmerican Airlines
Deal found 2/19$259
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/239:02 amDSM - GSP
1 stop11h 19mAllegiant Air
Fri 3/2810:05 pmGSP - DSM
1 stop17h 33mAllegiant Air
Deal found 2/20$281
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/15:50 amMLI - GSP
1 stop3h 49mDelta
Tue 5/611:45 amGSP - MLI
1 stop5h 35mDelta
Deal found 2/19$283
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/610:32 amDSM - GSP
1 stop6h 03mDelta
Mon 3/1012:00 pmGSP - DSM
1 stop8h 09mDelta
Deal found 2/20$297
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/146:00 amCID - GSP
1 stop7h 03mAmerican Airlines
Tue 4/154:16 pmGSP - CID
1 stop7h 52mAmerican Airlines
Deal found 2/18$298
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/297:00 amDSM - GSP
2 stops7h 37mAmerican Airlines
Sat 4/512:40 pmGSP - DSM
1 stop7h 21mAmerican Airlines
Deal found 2/20$302
This United deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/53:34 pmMLI - GSP
1 stop4h 40mUnited Airlines
Sun 3/96:40 amGSP - MLI
1 stop4h 39mUnited Airlines
Deal found 2/19$329
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/248:10 amCID - GSP
2 stops9h 55mUnited Airlines
Tue 3/45:15 pmGSP - CID
1 stop4h 46mUnited Airlines
Deal found 2/19$339
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/65:30 amOMA - GSP
1 stop4h 29mDelta
Sun 4/136:00 amGSP - OMA
1 stop6h 15mDelta
Deal found 2/20$367
This United deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/73:55 pmDBQ - GSP
1 stop5h 42mMultiple Airlines
Sat 4/126:30 amGSP - DBQ
1 stop9h 55mMultiple Airlines
Deal found 2/20$385
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/128:15 amOMA - GSP
2 stops11h 55mSouthwest
Sat 7/197:20 amGSP - OMA
2 stops10h 10mSouthwest
Deal found 2/19$407
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/233:30 pmDSM - GSP
3 stops27h 58mMultiple Airlines
Fri 3/2810:05 pmGSP - DSM
1 stop17h 33mMultiple Airlines
Deal found 2/20$408

Find flights from Iowa to Greenville within your budget

Customize your flight search to find flights from Iowa to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Iowa

Fly to

Greenville

Route

Depart

Return

Price

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Thu 3/6

3:25 pm-10:57 pm

1 stop6h 32m

Greenville

Sat 3/8

6:31 pm-10:04 pm

1 stop4h 33m

$259

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sun 3/23

9:02 am-9:21 pm

1 stop11h 19m

Greenville

Fri 3/28

10:05 pm-2:38 pm

1 stop17h 33m

$281

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Thu 5/1

5:50 am-10:39 am

1 stop3h 49m

Greenville

Tue 5/6

11:45 am-4:20 pm

1 stop5h 35m

$283

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Thu 3/6

10:32 am-5:35 pm

1 stop6h 03m

Greenville

Mon 3/10

12:00 pm-7:09 pm

1 stop8h 09m

$297

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Mon 4/14

6:00 am-2:03 pm

1 stop7h 03m

Greenville

Tue 4/15

4:16 pm-11:08 pm

1 stop7h 52m

$298

Des MoinesGreenville

DSM - GSP

DSMGSP

Des Moines

Sat 3/29

7:00 am-3:37 pm

2 stops7h 37m

Greenville

Sat 4/5

12:40 pm-7:01 pm

1 stop7h 21m

$302

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Wed 3/5

3:34 pm-9:14 pm

1 stop4h 40m

Greenville

Sun 3/9

6:40 am-10:19 am

1 stop4h 39m

$329

OmahaGreenville

OMA - GSP

OMAGSP

Omaha Eppley Airfield

Sun 4/6

5:30 am-10:59 am

1 stop4h 29m

Greenville

Sun 4/13

6:00 am-11:15 am

1 stop6h 15m

$367

DubuqueGreenville

DBQ - GSP

DBQGSP

Dubuque

Mon 4/7

3:55 pm-10:37 pm

1 stop5h 42m

Greenville

Sat 4/12

6:30 am-3:25 pm

1 stop9h 55m

$385

Cedar RapidsGreenville

CID - GSP

CIDGSP

Cedar Rapids

Tue 3/18

8:05 am-9:10 pm

2 stops12h 05m

Greenville

Tue 3/25

5:32 pm-9:36 pm

1 stop5h 04m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 25 results
1
2
3

Best time to book a flight from Iowa to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to Greenville

Get recent, data-driven insights about flights from Iowa to Greenville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to Greenville?

Currently, January is the cheapest month in which you can book a flight from Iowa to Greenville (average of $329). Flying from Iowa to Greenville in March is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to GSP?

Find hourly flight availability from Iowa to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Iowa to Greenville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Greenville by month

Plan your trip to Greenville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

Temperature in Greenville by month

Plan your trip to Greenville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated February 20, 2025.
Read through reviews of airlines operating flights from Iowa to Greenville, such as Southwest, Delta and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Comfort

8.1

Entertainment

7.6

Overall

8.1

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Comfort

8.1

Entertainment

7.6

Overall

8.1

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Comfort

8.1

Entertainment

7.6

Overall

8.1

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Comfort

8.1

Entertainment

7.6

Overall

8.1

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Comfort

8.1

Entertainment

7.6

Overall

8.1

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Comfort

8.1

Entertainment

7.6

Overall

8.1

Boarding

8.2

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Iowa?

    Greenville (GSP), located 10.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Greenville.

  • What are the cheapest airlines to fly from Iowa to Greenville one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $204. Users have also found prices from $264 and $264 on Southwest and Delta, respectively.

  • What are the most popular routes from Iowa to Greenville?

    When deciding which route to take from Iowa to Greenville consider Des Moines - Greenville, Moline Quad-City - Greenville or Cedar Rapids - Greenville as they are the most popular.

  • Can I find deals for flights from Iowa to Greenville that include hotel bookings?

    Yes. In addition to deals on Iowa to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Greenville.

  • Can I find deals for business class flights from Iowa to Greenville?

    Yes. Cheapflights offers flight deals from Iowa to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Greenville (average of $329). Flying from Iowa to Greenville in March is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Iowa?

Book flights to Iowa if you plan to visit one of these locations
Simpsonville
Seneca
Anderson

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Alternative routes for Iowa to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Iowa to Greenville

Discover the top 3 airlines that operate flights from Iowa to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$345FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$246Average$380FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$318Average$512FlexibilityNo cancel feeOn-time69%
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