$293+ Cheap flights from Des Moines to Greenville (DSM - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GSP
mar. 8 — mar. 151
1 adult, Economy
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Find cheap flights from Des Moines to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated marzo 3, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $293 (Delta) |
Popular in | November |
Cheapest in | January |
Average price | $421 |
Find flight deals from Des Moines to Greenville
Cheapest flights from Des Moines to GreenvilleExplore the most affordable flight options available from Des Moines to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 3, 2025.
Explore the most affordable flight options available from Des Moines to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 3, 2025.
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/247:20 amDSM - GSP
1 stop7h 19mDelta
mié. 3/267:00 amGSP - DSM
1 stop4h 40mDelta
Deal found 3/3![Delta logo]()
$293
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/242:07 pmDSM - GSP
1 stop4h 00mAmerican Airlines
mié. 3/264:17 pmGSP - DSM
2 stops6h 41mAmerican Airlines
Deal found 3/3![American Airlines logo]()
$298
This United deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/263:28 pmDSM - GSP
1 stop4h 18mUnited Airlines
dom. 3/306:30 amGSP - DSM
1 stop5h 14mUnited Airlines
Deal found 3/3![United Airlines logo]()
$410
This Mytrip deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/116:30 amDSM - GSP
1 stop7h 34mAllegiant Air
dom. 4/132:52 pmGSP - DSM
2 stops33h 16mAllegiant Air
Deal found 3/2![Allegiant Air logo]()
$416
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/117:00 amDSM - GSP
2 stops10h 35mSouthwest
dom. 4/1310:25 amGSP - DSM
2 stops14h 30mSouthwest
Deal found 3/2![Southwest logo]()
$518
Find flights from Des Moines to Greenville within your budget
Customize your flight search to find flights from Des Moines to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 3, 2025.
Fly from
Des Moines
Fly to
Greenville
Route
Depart
Return
Price
Des MoinesGreenville
DSM - GSP
DSMGSP
Des Moines
lun. 3/24
7:20 am-3:39 pm
1 stop7h 19m
Greenville
mié. 3/26
7:00 am-10:40 am
1 stop4h 40m
$293
Des MoinesGreenville
DSM - GSP
DSMGSP
Des Moines
lun. 3/24
2:07 pm-7:07 pm
1 stop4h 00m
Greenville
mié. 3/26
4:17 pm-9:58 pm
2 stops6h 41m
$298
Des MoinesGreenville
DSM - GSP
DSMGSP
Des Moines
mié. 3/26
3:28 pm-8:46 pm
1 stop4h 18m
Greenville
dom. 3/30
6:30 am-10:44 am
1 stop5h 14m
$410
Des MoinesGreenville
DSM - GSP
DSMGSP
Des Moines
vie. 4/11
6:30 am-3:04 pm
1 stop7h 34m
Greenville
dom. 4/13
2:52 pm-11:08 pm
2 stops33h 16m
$416
Des MoinesGreenville
DSM - GSP
DSMGSP
Des Moines
vie. 4/11
7:00 am-6:35 pm
2 stops10h 35m
Greenville
dom. 4/13
10:25 am-11:55 pm
2 stops14h 30m
$518
Compare providers for flights from Des Moines to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Greenville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Travel insights for flights from Des Moines to Greenville
Get recent, data-driven insights about flights from Des Moines to Greenville including ideal travel times, pricing trends, and more.
What is the cheapest month to book a flight from Des Moines to Greenville?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Greenville (average of $329). Flying from Des Moines to Greenville in March is currently the most expensive (average of $396). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to GSP?
Find hourly flight availability from Des Moines to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 3, 2025.
When flying from Des Moines to Greenville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 15% versus a flight in the morning.
Rainfall in Greenville by month
Plan your trip to Greenville by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.
Temperature in Greenville by month
Plan your trip to Greenville by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated marzo 3, 2025.
Boarding
8.2
Entertainment
7.6
Food
7.1
Overall
8.1
Comfort
8.1
Crew
8.7
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Boarding
8.2
Entertainment
7.6
Food
7.1
Overall
8.1
Comfort
8.1
Crew
8.7
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Boarding
8.2
Entertainment
7.6
Food
7.1
Overall
8.1
Comfort
8.1
Crew
8.7
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Boarding
8.2
Entertainment
7.6
Food
7.1
Overall
8.1
Comfort
8.1
Crew
8.7
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Boarding
8.2
Entertainment
7.6
Food
7.1
Overall
8.1
Comfort
8.1
Crew
8.7
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Boarding
8.2
Entertainment
7.6
Food
7.1
Overall
8.1
Comfort
8.1
Crew
8.7
Reviews
1 / 20
10.0
Merlyn,Feb 2025
LAX - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsSimpsonville
Seneca
Anderson
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Alternative routes for Des Moines to Greenville
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Des Moines to Greenville
Discover the top 2 airlines that operate flights from Des Moines to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 3, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$286 | Average$401 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$316 | Average$428 | FlexibilityNo cancel fee | On-time71% |