Grand Cayman

$156+ Cheap flights from South Carolina to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Apr 9 — Apr 161
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Cheap flight deals from South Carolina to Grand Cayman

Keep the following information in mind while searching for South Carolina to Grand Cayman flight deals. Data was last updated April 4, 2025.

Round-trip from

$420
(American Airlines)

One-way from

$156
(American Airlines)

Popular in

December

Cheapest in

May

Average price

$774
From South Carolina to Grand Cayman
One-way flight from South Carolina to Grand Cayman
Highest demand for flights based on searches. 25% potential increase in price ($212 potential increase over avg. RT price).
Cheapest flight prices on average. 13% potential price decrease ($76 potential savings vs. average RT price).
Average for round-trip flights in April 2025

Find flight deals from South Carolina to Grand Cayman

Cheapest flights from South Carolina to Grand Cayman
Explore the most affordable flight options available from South Carolina to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2025.

This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/36:20 pmGSP - GCM
2 stops17h 49mAmerican Airlines
Fri 5/912:25 pmGCM - GSP
1 stop10h 25mAmerican Airlines
Deal found 4/4$420
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/15:10 amCHS - GCM
1 stop7h 25mAmerican Airlines
Thu 5/812:25 pmGCM - CHS
1 stop10h 50mAmerican Airlines
Deal found 4/2$421
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/3010:19 pmCLT - GCM
1 stop24h 01mMultiple Airlines
Thu 5/811:30 amGCM - CLT
1 stop19h 44mMultiple Airlines
Deal found 4/4$445
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/17:00 amGSP - GCM
1 stop6h 30mUnited Airlines
Sat 5/101:45 pmGCM - GSP
1 stop8h 15mUnited Airlines
Deal found 4/4$527
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/137:00 amCLT - GCM
1 stop6h 30mUnited Airlines
Mon 8/181:35 pmGCM - CLT
1 stop7h 22mUnited Airlines
Deal found 4/3$540
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/265:23 amSAV - GCM
1 stop7h 02mDelta
Mon 6/3012:40 pmGCM - SAV
1 stop9h 27mDelta
Deal found 4/3$545
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/209:20 amCLT - GCM
Nonstop3h 00mAmerican Airlines
Sat 7/263:05 pmGCM - CLT
Nonstop3h 10mAmerican Airlines
Deal found 4/3$550
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/205:30 amCLT - GCM
1 stop7h 01mDelta
Sat 7/261:00 pmGCM - CLT
1 stop7h 06mDelta
Deal found 4/4$565
This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/110:25 amCHS - GCM
3 stops26h 15mMultiple Airlines
Thu 5/811:30 amGCM - CHS
2 stops33h 39mMultiple Airlines
Deal found 4/2$596
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/13:33 pmSAV - GCM
1 stop21h 57mUnited Airlines
Wed 5/71:35 pmGCM - SAV
1 stop6h 53mUnited Airlines
Deal found 4/3$632
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/308:41 pmCAE - GCM
1 stop15h 19mAmerican Airlines
Sat 9/612:45 pmGCM - CAE
1 stop7h 43mAmerican Airlines
Deal found 4/4$635
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/298:13 pmSAV - GCM
2 stops17h 57mAmerican Airlines
Sat 8/210:55 amGCM - SAV
1 stop7h 13mAmerican Airlines
Deal found 4/3$639

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
Use the filters below to find and compare flights from South Carolina to Grand Cayman that are best for you.

Fly from

South Carolina

Fly to

Grand Cayman

Route

Depart

Return

Price

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Sat 5/3

6:20 pm-11:09 am

2 stops17h 49m

George Town Owen Roberts Intl

Fri 5/9

12:25 pm-11:50 pm

1 stop10h 25m

$420

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 5/1

5:10 am-11:35 am

1 stop7h 25m

George Town Owen Roberts Intl

Thu 5/8

12:25 pm-12:15 am

1 stop10h 50m

$421

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 4/30

10:19 pm-9:20 pm

1 stop24h 01m

George Town Owen Roberts Intl

Thu 5/8

11:30 am-8:14 am

1 stop19h 44m

$445

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 5/1

7:00 am-12:30 pm

1 stop6h 30m

George Town Owen Roberts Intl

Sat 5/10

1:45 pm-11:00 pm

1 stop8h 15m

$527

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Wed 8/13

7:00 am-12:30 pm

1 stop6h 30m

George Town Owen Roberts Intl

Mon 8/18

1:35 pm-9:57 pm

1 stop7h 22m

$540

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Thu 6/26

5:23 am-11:25 am

1 stop7h 02m

George Town Owen Roberts Intl

Mon 6/30

12:40 pm-11:07 pm

1 stop9h 27m

$545

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 7/20

9:20 am-11:20 am

Nonstop3h 00m

George Town Owen Roberts Intl

Sat 7/26

3:05 pm-7:15 pm

Nonstop3h 10m

$550

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 7/20

5:30 am-11:31 am

1 stop7h 01m

George Town Owen Roberts Intl

Sat 7/26

1:00 pm-9:06 pm

1 stop7h 06m

$565

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 5/1

10:25 am-11:40 am

3 stops26h 15m

George Town Owen Roberts Intl

Thu 5/8

11:30 am-10:09 pm

2 stops33h 39m

$596

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Thu 5/1

3:33 pm-12:30 pm

1 stop21h 57m

George Town Owen Roberts Intl

Wed 5/7

1:35 pm-9:28 pm

1 stop6h 53m

$632

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/4

Showing 1-10 of 28 results
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Best time to book a flight from South Carolina to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Grand Cayman

What is the cheapest month to book a flight from South Carolina to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $467). Flying from South Carolina to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated April 4, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and American Airlines from South Carolina to Grand Cayman by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good
8.0
Very good

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
8.0
Very good

Boarding

8.2

Overall

8.0

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from South Carolina to Grand Cayman one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $156. However, be on the lookout for offers from Air Canada and United Airlines, as they are both options that can get you from South Carolina to Grand Cayman for a low price.

  • Can I find deals for flights from South Carolina to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on South Carolina to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Grand Cayman.

  • Can I find deals for business class flights from South Carolina to Grand Cayman?

    Yes. Cheapflights offers flight deals from South Carolina to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $467). Flying from South Carolina to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Grand Cayman

Discover the top 2 airlines that operate flights from South Carolina to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$375Average$578FlexibilityNo cancel feeOn-time71%
DeltaCheapest$460Average$602FlexibilityNo cancel feeOn-timeN/A

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