Grand Cayman

$208+ Cheap flights from South Carolina to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Apr 30 — May 71
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Cheap flight deals from South Carolina to Grand Cayman

Keep the following information in mind while searching for South Carolina to Grand Cayman flight deals. Data was last updated April 25, 2025.

Round-trip from

$462
(American Airlines)

One-way from

$208
(Kiwi.com)
From South Carolina to Grand Cayman
One-way flight from South Carolina to Grand Cayman

Find flight deals from South Carolina to Grand Cayman

Cheapest flights from South Carolina to Grand Cayman
Explore the most affordable flight options available from South Carolina to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/296:00 amCHS - GCM
1 stop6h 04mAmerican Airlines
Thu 7/312:25 pmGCM - CHS
1 stop10h 23mAmerican Airlines
Deal found 4/24$462
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/86:00 amCLT - GCM
1 stop6h 40mMultiple Airlines
Wed 6/1111:30 amGCM - CLT
1 stop19h 47mMultiple Airlines
Deal found 4/25$503
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/227:27 amGSP - GCM
1 stop4h 53mAmerican Airlines
Thu 5/2912:25 pmGCM - GSP
1 stop6h 37mAmerican Airlines
Deal found 4/25$545
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:45 amCHS - GCM
1 stop4h 52mDelta
Tue 12/22:02 pmGCM - CHS
1 stop9h 39mDelta
Deal found 4/24$551
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/209:20 amCLT - GCM
Nonstop3h 00mAmerican Airlines
Sat 7/263:05 pmGCM - CLT
Nonstop3h 10mAmerican Airlines
Deal found 4/25$575
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/295:30 amSAV - GCM
1 stop7h 01mDelta
Sat 8/21:00 pmGCM - SAV
1 stop7h 24mDelta
Deal found 4/25$590
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:30 amCHS - GCM
1 stop9h 55mUnited Airlines
Tue 12/25:35 pmGCM - CHS
1 stop28h 19mUnited Airlines
Deal found 4/24$612
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:40 amCAE - GCM
1 stop6h 51mDelta
Mon 9/2212:53 pmGCM - CAE
1 stop7h 55mDelta
Deal found 4/24$633
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/308:41 pmCAE - GCM
1 stop15h 19mAmerican Airlines
Sat 9/612:45 pmGCM - CAE
1 stop7h 43mAmerican Airlines
Deal found 4/25$635
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/296:33 amSAV - GCM
2 stops7h 37mAmerican Airlines
Sat 8/210:55 amGCM - SAV
1 stop10h 41mAmerican Airlines
Deal found 4/25$639
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/88:20 pmCLT - GCM
2 stops16h 30mSouthwest
Wed 6/1112:45 pmGCM - CLT
2 stops8h 55mSouthwest
Deal found 4/25$685
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/912:33 pmCHS - GCM
3 stops28h 37mMultiple Airlines
Mon 6/1612:50 pmGCM - CHS
3 stops32h 39mMultiple Airlines
Deal found 4/25$722

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
Use the filters below to find and compare flights from South Carolina to Grand Cayman that are best for you.

Fly from

South Carolina

Fly to

Grand Cayman

Route

Depart

Return

Price

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sun 6/29

6:00 am-11:04 am

1 stop6h 04m

George Town Owen Roberts Intl

Thu 7/3

12:25 pm-11:48 pm

1 stop10h 23m

$462

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 6/8

6:00 am-11:40 am

1 stop6h 40m

George Town Owen Roberts Intl

Wed 6/11

11:30 am-8:17 am

1 stop19h 47m

$503

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Thu 5/22

7:27 am-11:20 am

1 stop4h 53m

George Town Owen Roberts Intl

Thu 5/29

12:25 pm-8:02 pm

1 stop6h 37m

$545

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 7/20

9:20 am-11:20 am

Nonstop3h 00m

George Town Owen Roberts Intl

Sat 7/26

3:05 pm-7:15 pm

Nonstop3h 10m

$575

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Tue 7/29

5:30 am-11:31 am

1 stop7h 01m

George Town Owen Roberts Intl

Sat 8/2

1:00 pm-9:24 pm

1 stop7h 24m

$590

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Thu 5/8

6:37 am-11:20 am

1 stop5h 43m

George Town Owen Roberts Intl

Mon 5/12

12:35 pm-9:10 pm

1 stop7h 35m

$596

ColumbiaGeorge Town

CAE - GCM

CAEGCM

Columbia Metropolitan

Thu 9/18

5:40 am-11:31 am

1 stop6h 51m

George Town Owen Roberts Intl

Mon 9/22

12:53 pm-9:48 pm

1 stop7h 55m

$633

ColumbiaGeorge Town

CAE - GCM

CAEGCM

Columbia Metropolitan

Sat 8/30

8:41 pm-11:00 am

1 stop15h 19m

George Town Owen Roberts Intl

Sat 9/6

12:45 pm-9:28 pm

1 stop7h 43m

$635

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Tue 7/29

6:33 am-1:10 pm

2 stops7h 37m

George Town Owen Roberts Intl

Sat 8/2

10:55 am-10:36 pm

1 stop10h 41m

$639

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 6/8

8:20 pm-11:50 am

2 stops16h 30m

George Town Owen Roberts Intl

Wed 6/11

12:45 pm-10:40 pm

2 stops8h 55m

$685

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Showing 1-10 of 23 results
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Best time to book a flight from South Carolina to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Grand Cayman

What is the cheapest month to book a flight from South Carolina to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $467). Flying from South Carolina to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated April 25, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from South Carolina to Grand Cayman by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
8.0
Very good

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from South Carolina to Grand Cayman one-way?

    The cheapest airline one-way is Air Canada, with whom users have recently found tickets for as low as $213. However, be on the lookout for offers from Southwest and American Airlines, as they are both options that can get you from South Carolina to Grand Cayman for a low price.

  • Can I find deals for flights from South Carolina to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on South Carolina to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Grand Cayman.

  • Can I find deals for business class flights from South Carolina to Grand Cayman?

    Yes. Cheapflights offers flight deals from South Carolina to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $467). Flying from South Carolina to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Grand Cayman

Discover the top 2 airlines that operate flights from South Carolina to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$375Average$579FlexibilityNo cancel feeOn-time71%
DeltaCheapest$460Average$627FlexibilityNo cancel feeOn-timeN/A

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