HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Grand Cayman

$228+ Cheap flights from Missouri to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
STL — GCM
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Grand Cayman with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Grand Cayman

Keep the following information in mind while searching for Missouri to Grand Cayman flight deals. Data was last updated febrero 20, 2025.

Round-trip from

$484
(Delta)

One-way from

$228
(United Airlines)
From Missouri to Grand Cayman
Search Deals
One-way flight from Missouri to Grand Cayman
Search Deals

Find flight deals from Missouri to Grand Cayman

Cheapest flights from Missouri to Grand Cayman
Explore the most affordable flight options available from Missouri to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/135:35 amMCI - GCM
1 stop6h 03mDelta
mar. 3/181:03 pmGCM - MCI
1 stop7h 04mDelta
Deal found 2/20$484
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/186:00 amSTL - GCM
1 stop5h 38mDelta
mar. 3/251:03 pmGCM - STL
1 stop10h 28mDelta
Deal found 2/18$484
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/206:24 pmSTL - GCM
2 stops17h 21mAmerican Airlines
lun. 3/243:34 pmGCM - STL
2 stops18h 08mAmerican Airlines
Deal found 2/19$488
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/296:15 amSTL - GCM
1 stop9h 35mUnited Airlines
mar. 4/11:35 pmGCM - STL
1 stop8h 34mUnited Airlines
Deal found 2/19$511
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/256:30 amMCI - GCM
1 stop6h 55mAmerican Airlines
mié. 4/212:45 pmGCM - MCI
2 stops9h 45mAmerican Airlines
Deal found 2/20$515
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/299:10 pmSTL - GCM
2 stops14h 40mSouthwest
mar. 4/112:45 pmGCM - STL
2 stops7h 45mSouthwest
Deal found 2/19$515
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/196:05 amMCI - GCM
1 stop9h 20mUnited Airlines
jue. 3/204:40 pmGCM - MCI
1 stop16h 55mUnited Airlines
Deal found 2/20$526
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 2/239:20 pmMCI - GCM
2 stops14h 35mSouthwest
mar. 2/251:50 pmGCM - MCI
1 stop9h 20mSouthwest
Deal found 2/19$730
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/1612:15 pmSTL - GCM
3 stops33h 05mMultiple Airlines
vie. 3/214:45 pmGCM - STL
3 stops43h 00mMultiple Airlines
Deal found 2/19$763
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/138:05 pmMCI - GCM
1 stop19h 40mMultiple Airlines
lun. 3/172:00 pmGCM - MCI
2 stops20h 35mMultiple Airlines
Deal found 2/20$769
This Justfly.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/196:25 pmMCI - GCM
2 stops19h 35mAir Canada
vie. 3/213:00 pmGCM - MCI
2 stops23h 26mAir Canada
Deal found 2/20$2,050

Find flights from Missouri to Grand Cayman within your budget

Customize your flight search to find flights from Missouri to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Missouri

Fly to

Grand Cayman

Route

Depart

Return

Price

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

jue. 3/13

5:35 am-11:38 am

1 stop6h 03m

George Town Owen Roberts Intl

mar. 3/18

1:03 pm-12:04 am

1 stop11h 01m

$484

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

mar. 3/18

6:00 am-11:38 am

1 stop5h 38m

George Town Owen Roberts Intl

mar. 3/25

1:03 pm-11:31 pm

1 stop10h 28m

$484

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

jue. 3/20

7:13 am-1:25 pm

1 stop6h 12m

George Town Owen Roberts Intl

lun. 3/24

3:34 pm-8:09 am

2 stops16h 35m

$488

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

sáb. 3/29

6:15 am-3:50 pm

1 stop9h 35m

George Town Owen Roberts Intl

mar. 4/1

1:35 pm-10:09 pm

1 stop8h 34m

$511

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

vie. 3/28

5:09 am-2:34 pm

1 stop9h 25m

George Town Owen Roberts Intl

mar. 4/1

3:34 pm-10:53 pm

1 stop7h 19m

$511

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

sáb. 3/29

9:10 pm-11:50 am

2 stops14h 40m

George Town Owen Roberts Intl

mar. 4/1

12:45 pm-8:30 pm

2 stops7h 45m

$515

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

mié. 4/23

6:20 am-12:30 pm

1 stop6h 10m

George Town Owen Roberts Intl

lun. 4/28

1:35 pm-10:19 pm

1 stop8h 44m

$524

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

mié. 4/23

2:04 pm-9:20 pm

3 stops31h 16m

George Town Owen Roberts Intl

lun. 4/28

2:00 pm-12:59 pm

3 stops46h 59m

$639

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

dom. 3/16

12:15 pm-9:20 pm

3 stops33h 05m

George Town Owen Roberts Intl

vie. 3/21

4:45 pm-11:45 am

3 stops43h 00m

$763

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

mié. 3/19

6:25 pm-2:00 pm

2 stops19h 35m

George Town Owen Roberts Intl

vie. 3/21

3:00 pm-2:26 pm

2 stops23h 26m

$2,050

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 12 results
1
2

Best time to book a flight from Missouri to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Grand Cayman

Get recent, data-driven insights about flights from Missouri to Grand Cayman including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Grand Cayman?

Currently, January is the cheapest month in which you can book a flight from Missouri to Grand Cayman (average of $467). Flying from Missouri to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to LAW?

Find hourly flight availability from Missouri to Grand Cayman. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Grand Cayman as you normally would.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated febrero 20, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Missouri to Grand Cayman. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Air Canada
7.0
Good
8,748 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Boarding

8.2

Food

7.1

Comfort

8.1

Overall

8.1

Crew

8.7

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Missouri to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on Missouri to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Grand Cayman.

  • Can I find deals for business class flights from Missouri to Grand Cayman?

    Yes. Cheapflights offers flight deals from Missouri to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Grand Cayman (average of $467). Flying from Missouri to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
Newark to George Town flights
John F Kennedy Intl to George Town flights
LaGuardia to George Town flights
O'Hare Intl to George Town flights
Boston to George Town flights
Dallas/Fort Worth to George Town flights
Miami to George Town flights
Baltimore to George Town flights
Dulles Intl to George Town flights
Reagan-National to George Town flights
Atlanta to George Town flights
Charlotte to George Town flights
Philadelphia to George Town flights
Minneapolis to George Town flights
Los Angeles to George Town flights
Denver to George Town flights
Seattle to George Town flights
Tampa to George Town flights
Orlando to George Town flights
Pittsburgh to George Town flights
Cleveland to George Town flights
St. Louis to George Town flights
George Bush Intcntl to George Town flights
Hobby to George Town flights
Indianapolis to George Town flights
Midway to George Town flights
Cincinnati to George Town flights
Sky Harbor Intl to George Town flights
Raleigh to George Town flights
Columbus to George Town flights
San Francisco to George Town flights
Fort Lauderdale to George Town flights
Detroit to George Town flights
Kansas City to George Town flights
Love Field to George Town flights
Richmond to George Town flights
Austin to George Town flights
Ontario to George Town flights
Milwaukee to George Town flights
Little Rock to George Town flights
Omaha to George Town flights
Hartford to George Town flights
Portland to George Town flights
Lexington to George Town flights
Nashville to George Town flights
West Palm Beach to George Town flights
Albuquerque to George Town flights
White Plains to George Town flights
Providence to George Town flights
Louisville to George Town flights

Top 3 airlines flying from Missouri to Grand Cayman

Discover the top 3 airlines that operate flights from Missouri to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$439Average$596FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$440Average$602FlexibilityNo cancel feeOn-time69%
DeltaCheapest$471Average$585FlexibilityNo cancel feeOn-timeN/A
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.